5XUY


Conserved Protein Domain Family
ATG101

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pfam07855: ATG101 
Autophagy-related protein 101
Atg101 is a critical autophagy factor that functions together with ULK, Atg13 and FIP200. Atg101 has been shown to be a HORMA (Hop1, Rev7 and MAD2) domain protein with an open conformation.
Statistics
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PSSM-Id: 462290
Aligned: 98 rows
Threshold Bit Score: 117.641
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5XUY_B        11 SVEGRQVEEAMLAVLHTVLLHRSTGKFHYaaagtysigtvgtQDVDCdfI-DFTYVRVSSeeLDRALRKVVGEFKDALRn 89 
XP_004233428  12 DVEHFEIREVLRCILHTIMFHRALGLLRP-------------KDVDLelF-DITYTQCGDveVEKKIEEKITLFIDRVEk 77 
XP_006338230  12 DVEQFEIQDVLQCILHTIMFHRASGLIYP-------------KNVDLelF-EITYMQCNDvvIERKIDEKITQFIDKVKk 77 
XP_002310165  12 EVEHFEIREVLRCILHTIVFHRALGLVRP-------------KDIDLelF-DITYVQCGEveLEKKIEEKIDQFISWVEk 77 
EFH42984      12 EVESFEIREVLRCILHTIVFHRALGLIRP-------------KDIDLelF-EITYVQCGEieVEKKIDEKIEQFINWIEk 77 
KRH04713      12 ELEHFEIREVLRCILHTIVFHRALGLVRP-------------KDVDLelF-DVTYVQCGEaeLEKKIDEKIEQFVCWVEk 77 
XP_002270399  12 ELENFQIREVLRCILHTIVFHRALGLVRP-------------KDIDLelF-EITYVQCGDaeVERKINEKIDQFISWVEk 77 
EFN56906      14 ELEQHQVHEVLRILLHTIVFNRALGPVKP-------------VERDSelF-AVTWVECGDpeVSRKVEEKIGQFGAWVQr 79 
XP_002501928  12 rCEAFQAKETLRAVLHTILFARTLGVVRA-------------RDVDSelF-DLTYTTCGDpaVERHVEERLDALVRWLAk 77 
XP_003057605  12 RCEARQAKEALRALTHTILLARALGPCAP-------------SDVDSalFpDLTYVTCGDadVERVVEARLGAFASWTAk 78 
5XUY_B        90 --SGGDGL--------GQMSLEFYQKK-KS--RW-PfSDECI-PWEVWTVKVHVVA-Lat------------------eQ 135
XP_004233428  78 ---hPNRK--------NQICLSFCEVKnKQa-SWfTtKVERF-YWEHWYINLNVAHhPkghpgkshls-kvvdpgesasE 143
XP_006338230  78 ---hPNQK--------HQICVSFYESKnKQt-SWfTkKVEHR-YWEHWYVNLNVAHhPkpdsgksrds-kvvnpeesapD 143
XP_002310165  78 ---hPNKK--------SQICLSFYETKnKHp-SWf-nKTERL-FWEQWYVNLHVTQhTkahsgkshhskpmvdlgetvsE 143
EFH42984      78 ---hPNKK--------SQICLSFYEVKsKQp-SWfTnKIERL-YWEQWYINLNVLQpAkppvgkshhs-klvmdpgeasE 143
KRH04713      78 ---hPNKK--------SQICLSFYEVKnKQa-SWfSnKIERL-YWEQWYINLNVAQhPkahsskyhhs-kvvdpgegalE 143
XP_002270399  78 ---hPNKK--------SQICLSFYEVKnKQa-SWfTnKIERR-SWEYWYINLNVAQhPkahsskshhskavvdpgesasE 144
EFN56906      80 ---nPGKR--------GQVCLSFYEKRqRQ--SWfStAEERL-YWEQWVLEVAVAEpPpaefeeq--------qafaasS 137
XP_002501928  78 qdRADDTV--------AQVCLSFYETKdKRggGWfGgGDERV-YWEQWRVPIEVVGgdea---------------lmnvA 133
XP_003057605  79 rgRDVARRggdareiyARVCVSFFERDrGDrgGGlGgSGSGSgAWEQWRIPIEVTLeSgdggeg---------ddaaaaR 149
5XUY_B       136 ERQICREKVGEKLCEKIINIVEVMn-RHEYLPKM 168
XP_004233428 144 ERSARRTVLESSLREVMFQIIKFVneKKDHIPAI 177
XP_006338230 144 EREAWHSGLELSLREVLFQIINFVkeKKDHIPLI 177
XP_002310165 144 DRGVRREALEASLHEVLFQIIKFVneKKDHVPPI 177
EFH42984     144 ERSSRRTLLEQSLQEVLFQIIKFVneKKDHVPPI 177
KRH04713     144 DRNARSAALEASLREVLFQIIKFVneKKDHVPPI 177
XP_002270399 145 DRSLRRAALEASLREVLFQIIKFVneKKDHIPSI 178
EFN56906     138 LRAQRRQRLQAAIEEGLTCIVRAVndKRDHIPPV 171
XP_002501928 134 DREAKSAELQQTIVAATQHVLGLVneRKDHIPPV 167
XP_003057605 150 AREERSLALRDEIRGAITHALTLAneRVAHVPPV 183
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