Conserved Protein Domain Family
TFP_LU_ECD_UP
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cd23627: TFP_LU_ECD_UP 
extracellular domain (ECD) found in urinary proteins (UP1-3) and similar proteins
The family includes UP1 (also called liver regeneration-related protein LRRG05), UP2 and UP3, which are secreted proteins containing an extracellular domain (ECD) that belongs to Ly-6 antigen/uPA receptor-like (LU) superfamily and exhibits a snake toxin-like fold (also known as three-finger toxin/3FTx fold or three-fingered protein/TFP domain fold).
Links
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Statistics
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PSSM-Id: 467147
Aligned: 7 rows
Threshold Bit Score: 115.427
Created: 28-Nov-2018
Updated: 27-Apr-2023
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P81828        18 SLLALQCFRCTSFDSTGFCHVGRQKCQTYPDEICAWVVvTTRDGKFVYGNQSCAECNATTVEHGSlIVSTNCCSATPFCN 97  Norway rat
NP_001030122  18 SLLALQCFRCESLDSTGLCRVGRRICQTYPDEICAWVVvTTRDGKFVYGNQSCAECIGTTVEHGSlIISTNCCSATPFCN 97  Norway rat
P83121        18 SLLALQCFRCISFDSTGFCYVGRHICQTYPDEICAWVVvTTRDGKFVYGNQSCAECNATTVEHGSlIVSTNCCSATPFCN 97  Norway rat
NP_001244024  18 SLQALVCFECGNLNSMGICNFRTAVCYAHPGEVCASVL-TYKDGKFVYGNQSCAECSGRTVEHGSlIVSTNCCSATSFCN 96  Norway rat
P81827        18 SLLALQCFRCESLDSTGLCRVGRRICQTYPDEICAWVVvTTRDGKFVYGNQSCAECIGTTVEHGSlIISTNCCSATPFCN 97  Norway rat
AEZ68748      18 SLLALQCFRCNSFDSTGFCHVGRHICQTYPDEICAWVVvTTRDGKFVYGNQSCAECNATTVEHGSlIVSTNCCSATPFCN 97  Norway rat
XP_003754733  18 SLQALQCFLCNRYSSEGNCVTGRLICQTKPDEICATVV-IYKDGKFDYGRQKCAECFSGTIEHGSrTVTTNCCSGSSFCN 96  Norway rat

P81828        98 M 98  Norway rat
NP_001030122  98 M 98  Norway rat
P83121        98 M 98  Norway rat
NP_001244024  97 I 97  Norway rat
P81827        98 M 98  Norway rat
AEZ68748      98 M 98  Norway rat
XP_003754733  97 R 97  Norway rat
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