3DLU,1KVV


Conserved Protein Domain Family
SRP19

?
pfam01922: SRP19 
SRP19 protein
The signal recognition particle (SRP) binds to the signal peptide of proteins as they are being translated. The binding of the SRP halts translation and the complex is then transported to the endoplasmic reticulum's cytoplasmic surface. The SRP then aids translocation of the protein through the ER membrane. The SRP is a ribonucleoprotein that is composed of a small RNA and several proteins. One of these proteins is the SRP19 protein (Sec65 in yeast).
Statistics
?
PSSM-Id: 460383
Aligned: 199 rows
Threshold Bit Score: 64.8054
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
3DLU_A                 5 VVWPSELDSRLSRKYGRIVPRSIAVESPRVEEIVRAAEELKFKVIr--VEEDKLNPRLsgideELrt------------- 69  Pyrococ...
Q9YDZ7                19 ILWPAYFDSTLPRRLGRRVPRDMGVPSPKPEDVAEAARRAGFEAV---VE-ESSYPRL-----WWrv------------- 76  Aeropyr...
jgi:Nmar_0519          8 VIWLDYFNKNLKKSKGRRLGLEKCVFDPSLKELTDAAKAAGFEITe--SDDKVRFPKRp----FVr-------------- 67 
goetting:Ngar_c15270   8 VLWLDYFNKNLKRRQGRKVNREQAVFDPTVQELAEAAKAAGFQFSdqeVNDNARFPRRs----FTr-------------- 69 
BAJ47268               8 ILWPVYFDSKSSRKQGRRVSRGLAVQRPSADDLAAACRRLGYEVE----KNDAAYPRR-----WSrr------------- 65 
WP_014736738          11 VIYPHYIDCSSTRSEGRRVPKSLCVPNPTLEEIEKAARRLGFEVE---VEADKKYPRM-----WRk-------------- 68  Thermog...
licsiro:TALC_00338    10 TLWPEYFDAERTRAEGRRLPLSLCVKRPSLDMIAKGAITLDLDYK---IYEDKCYPGD-----WIak------------- 68 
WP_022532979          10 VLWPEYFDSGLTRAQGRRLPTALCVKQPSLDMIAKGAILLDLEYR---VIEDKSYPSD-----WPsk------------- 68  Candida...
EHY64888               5 RIYPIYFNRGIKRSQGRKVPFSSNSKPVTLQQLLKALIQLKIEYK---VE-TKQHPKHs----YAlcaeclpaatkpeev 76 
EIJ87917               5 RIYPIYFNSGIKRSQGRKVPFRNNAKAVTLQQLLKALNQLKIEYT---VE-TKQHPKHs----YElcaqflpstskpeev 76 
3DLU_A                70 -------fGMIVLES--PY-GKSKSLKLIAQKIREF 95  Pyrococcus furiosus
Q9YDZ7                77 -------rRRIVVLApeDV-SKTDIIKAVATELRKI 104 Aeropyrum pernix K1
jgi:Nmar_0519         68 -------sGYVVLPK--GS-SKTKILNKISEKLVAK 93 
goetting:Ngar_c15270  70 -------sGYVMVAKke-gvKKSQVIDAVAEKIVQR 97 
BAJ47268              66 -------tGYVVVKPrp-kiSKNMFLKMVAEELRKH 93 
WP_014736738          69 -------aGRVVVNK--VF-SKTRLLKLISMELKKT 94  Thermogladius calderae
licsiro:TALC_00338    69 -------kGCVRVEK--GKmKKGEILPKIGEVLVKN 95 
WP_022532979          69 -------rGCVRVEK--GKmKKSEILPKIGEILVKN 95  Candidatus Methanomethylophilus alvus
EHY64888              77 erlfsttgGSVMIT---TD-SKRQLIKEINDLLSTN 108
EIJ87917              77 erlfsttgGAVKIT---TD-SKRQLIKDIDNLLNGS 108
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap