Conserved Protein Domain Family
Mito_fiss_reg

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pfam05308: Mito_fiss_reg 
Mitochondrial fission regulator
In eukaryotes, this family of proteins induces mitochondrial fission.
Statistics
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PSSM-Id: 461620
Aligned: 49 rows
Threshold Bit Score: 214.815
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_011217831  23 LQIREKKDYGSARSIVRIIGKILPLEPCPRPNFELIPLLNS----VDSGNCGSVVPSFADILCVANDEEASYLRF---RN 95 
XP_003759778  22 SVLWSGKPYGSSRSIVRKIGTNLSLIQCPRVQFQLTSHLTEw---SPNQYQGDAVASFADVGWVAREEREVSTRL---RT 95 
G3V9A7        22 SVLWSGKPYGSSRSIVRKIGTNLSLIQCPRVQFQLTSHATEw---SPTHPGEDVVATFADVGWVATDEGECSTRL---RT 95  Norway rat
8_pfamImport   1 SVLWSGKPYGSSRSIVRKIGSNLSLIQCPRVQFQLTSPTTEw---SPSHPREDAVVSFADVGWVAKEEGECSTRR---RT 74 
Q3SZL7        21 SVLWSGKPYGSSRSIVRKIGTNLSLIQCPRVQFQLTSPTTEw---SSSPSGEDAVVSFADVGWVAEEEGECSTRQ---RI 94  cattle
XP_013852174  21 SVLWSGKPYGSSRSIVRKIGTNLSLIQCPRVQFQLTSPTTEw---SPSNPEEDAVVSFADIGWVAKEDGECSTRR---RA 94 
Q9PTD5        22 SVLWSSKPYGSSRSIVRKIGTNLSLIQCPRVQFQLTSQAAEg--nHPHQFREDAVASFADVGWVAQEEGEVSTRL---RS 96  chicken
XP_012427557  22 SVLWSSKPYGSSRSIVRKIGTNLSLIQCPRVHFQLISHVTEg--nTPAQLREDAVASFADVGWIAEEESEVSTRL---RS 96 
CAG04195      12 LAVTAAKSYGSSRSIVRRIATSLPLKPCPRVHFQLYPYNEDanvlIGERRKNGFVASLADIAWLDRDEEDDEGYFvnpRS 91  spotted green p...
XP_001512050  22 SVLWSGKSYGSSRSIVRKIGTNLSLIQCPRVHFQLTSHSTEc---SPNHPREDAVASFADVGWVAREEGEVSTRL---RT 95  platypus
XP_011217831  96 SLWKP----EEEEKMEFFHSLQPVWNPLSPALQQNKRMKS-DGPVGEAAFKKIAALEEELTFLRTQIAAIVGRREPRTSa 170
XP_003759778  96 EVGSKp---APPDEFHFFEKPPNRHLSLPNLAPEDPEPKV-TALANDEALQKINALEHELATLRAQIAKIVTLQEQQSL- 170
G3V9A7        96 EVRSKp---PLENNPPCFEKPPSRHISLPNSSQDKPSPKT-T-LASEEALQKISALENELAALRAQIAKIVTLQEQQSP- 169 Norway rat
8_pfamImport  75 EVRSRq---PLQDDLPFFEKLPSRQFSLPNLSPEDPQQKT--ALANEEALQKISALENELAALRAQIAKIVTLQEQQNL- 148
Q3SZL7        95 EVRSRp---TLQDDLPFFEKPHSRQPSLPTLSPEEPPLQT-STLANEEALQKICALESELAALRAQIAKIVTLQEQQNL- 169 cattle
XP_013852174  95 EVRSRq---PLQDELPFFEQPPSRQFSFPSLSPEEPQLQT-TILANEEALQKICALESELAALRAQIAKIVTLQEQQNL- 169
Q9PTD5        97 EVWSKta-qPLPGELHQPGHSLGRQDSVPNLLHEEPAPRS-TVIANEEAMQKISALENELATLRAQIAKIVILQEQQNL- 173 chicken
XP_012427557  97 EVWTKtt-qPLPGEAHHSRKSPHRQTSLQSPSGEEPVPRS-AVMANEEALQKISALENELASLRAQIAKIVTLQEQQNL- 173
CAG04195      92 GMQAGf--vFRAHQPHPQRKLLPRQRSLPSLHQGARDPQA-PSAANDEAIQKISVLETELAKLRAQIAQIVLAQERATQ- 167 spotted green p...
XP_001512050  96 EVWSQetpsPGPQNLPFFGQPPSRQSSLPNLPRAEPEPKTpTALANDEALQKISALENELATLRAQIAKIVTLQEQQSL- 174 platypus
XP_011217831 171 hAGFFDLSDEPSGLEQRTSPGTAetsaqpdlfssslLFPPPPPPLPsqlfspqpacsplTRPGSNNMRDSDNSANEMKKQ 250
XP_003759778 171 -TAGGLSPTTPTIAPPSPAVPPP--------------PLPPPPPPP-------------PL--PSSRLRQSVSAIDLIKE 220
G3V9A7       170 -SAGCLDSSTPVIV----VPPPP--------------PPPPPPPPL-------------PP--PPLVLHPSTSALDLIKE 215 Norway rat
8_pfamImport 149 --------------------------------------IAG-------------------------LHQSVSSAIDLIKE 165
Q3SZL7       170 -SAGDLESTRPAAAAAPSVPPAP--------------PLPPPPPPL-----------------PSPGLQQSTSAIDLIKE 217 cattle
XP_013852174 170 -SAGDLDSTTSVATAPPSVPPAP--------------PLPPPPPPP-------------PL--PPSGFHQNTSVIDLIKE 219
Q9PTD5       174 -TAAGLSPVASAAVPCVPPPPPP--------------PPPPPLPPP--------------------ALQQSMSAIELIRE 218 chicken
XP_012427557 174 -TTVGSSPLASAAVP-APPPPPP--------------PPPPPLPPP-----------------PPSSLHQSKSAIDLIKE 220
CAG04195     168 ----------PGTPHTLl-------------------------------------------------------------- 175 spotted green p...
XP_001512050 175 --------GAGSFSAPGPGPPPP-------------PPPPPPPPPP-------------PPPPPPPGLSRSMSAIDLIKE 220 platypus
XP_011217831 251 HPGDSKT---TYShSKNQENKDVPNMLDILKDMNKVKLR 286
XP_003759778 221 RRE-KKTsagKILiENSPKKPEVPNMLEILKDMNNVKLR 258
G3V9A7       216 RRE-QRLsagKTLaKGHPKKLDMPNMLEILKDMNSVKLR 253 Norway rat
8_pfamImport 166 RRE-KKA----CAgKSSPKKPDVPNMLEILKDMNSVKLR 199
Q3SZL7       218 RRR-RNAsagKTPvKNSPKKTDLPNMLEILKDMNSVKLR 255 cattle
XP_013852174 220 RKE-KNAragKTSvKNSPKKPAMPNMLEILKDMNSVKLR 257
Q9PTD5       219 RKN-RKTnsgPIPtENGPKKPEIPNMLEILKDMNSVKLR 256 chicken
XP_012427557 221 RKN-QKMnagQNVvENGPKKPEVPNMLEILKDMNSVKLR 258
CAG04195         ---------------------------------------     spotted green pufferfish
XP_001512050 221 RREKKASp-sPSPtENTPKKPDVPSMLEILKDMNTVKLR 258 platypus
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