Conserved Protein Domain Family
MRI

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pfam15325: MRI 
Modulator of retrovirus infection
MRI, or modulator of retrovirus infection, is a family of eukaryotic proteins that regulate the activity of the proteasome in the uncoating of retroviruses.
Statistics
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PSSM-Id: 434635
Aligned: 11 rows
Threshold Bit Score: 97.1748
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6AYH4        57 MNEAEMVDVALGILI-EGRKQEKPWEQPSLVAPDKLQLSPPCSESPHTSSp----GSSSEEEDSRTDSPAL--GLSPARG 129 Norway rat
XP_003791649  56 LNEAELVDVALGILI-ESHKQEMPWKQLSQGGSDNPERSPTCSTSPHTSS-----GSSNEEENSGKDTPSP--GLGPSLG 127
XP_873785     55 MNEAEVVDVALGILIeEDRKQEKPLEPPPLAGADKPERSPA-SPAPPSPSprwsrSEDSEEEDRGADGPAP--------G 125
XP_019663892  57 MSEAEMVDVALGILI-EAREQEKPWESPTLAGADKPELSPTCSTLSPSSP-----GSRSEDEDNGKDALPP--GLKPPQG 128
XP_010598738  56 MNEAEVVDAALAVLI-EGRKWEKSLEQKAPAKADKLELSPRSLRSPWSP------GGRSEDKDNGEDSLPP--SLGPSQE 126
XP_007504425  58 MNEAELVDVALGVLV-ECRKQEKPLEHTLLLGTDKDQTAQP--ESPWAS------GSRSDGEEEVDDTPQT--HPSSKQE 126
XP_023609279  58 MSEAELVDVALGVLI-ENRQQEKALEQRPLAGTAEPELSPTCSEGPASPE-------TSEGEDSGEAALPP--GLGRPQG 127
XP_004851279  55 MNEAELVDVALGILI-EGRTQEKPWEELAVAGAEKTELCPTGSRSPHTSS-----GGNSDEEDSGNHGLRPeaGPSPSQR 128
XP_008256363  53 MNETELVDVALGILI-EDGKQEKAGELPSLLGADKPEGSPS--PSPHTSS-----GSSSDEEEGEDDAPVP--GLSPPNT 122
XP_016813674  56 MNEAEIVDVALGILI-ESRKQEKACEQPALAGADNPEHSPPCSMSPHTSS-----GSSSEEEDSGKQALAP--GLSPSQR 127
XP_003475590  55 MNEAEMVDVALGILL-EGHAWEKPQEELAVGGTEKAELCPAGPWSPHTSS-----GGNSEEEDSENDRPTL--GLSSSQR 126 domestic guinea...
Q6AYH4       130 PEASNSPCSRSP-------------EEgkeEEDELKYVREIFFS 160 Norway rat
XP_003791649 128 PGVSDSACSGSP-------------EK---DEDELKYVREIFFS 155
XP_873785    126 PAGSDTACSRSL-------------EE---DQDELKYVREIFFS 153
XP_019663892 129 CTGSDPACSRSP-------------EEd-eDEDVLKYVREIFFS 158
XP_010598738 127 LGGSDSTHSESQ-------------KE---EEDALKYVREIFFS 154
XP_007504425 127 CSASGYKKGSGD-------------EE---NEDALKYVREIFFS 154
XP_023609279 128 PAGLEPACSSSP-------------EE---DEDAFKYVREIFFS 155
XP_004851279 129 PETFTSACSRSP-------------EQq--EEDVFKYVREIFFS 157
XP_008256363 123 AGGRRP-EEEEK-------------EE---EEDVLKYVREIFFS 149
XP_016813674 128 PGGSSSACSRSP-------------EEe-eEEDVLKYVREIFFS 157
XP_003475590 127 PGMPTSACNRDPkqeeeeevkeekvEEeeeAEDVFKYVREIFFS 170 domestic guinea pig
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