4M3O


Conserved Protein Domain Family
RPAP2_Rtr1

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pfam04181: RPAP2_Rtr1 
Rtr1/RPAP2 family
This family includes the human RPAP2 (RNAP II associated polypeptide) protein and the yeast Rtr1 protein. It has been suggested that this family of proteins are regulators of core RNA polymerase II function.
Statistics
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PSSM-Id: 461212
Aligned: 117 rows
Threshold Bit Score: 41.8127
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4M3O_A        54 RFLTKQDYADLVQERNLVKRCGYPLCSKSQarVRdpf-adVQMTNFLRQ-----NNPYAYL-------------TEYCTK 114  Kluyveromyces ...
CRZ24385      40 NSLDQNSWMEVIEERYLGRMCGFPLCANSVevKN--------SQKYRIDlknkkVFERSAEi------------DKFCSQ 99  
P30641        39 PHLHCLGWDEVVEERYVNKQCGFPSCQKAPpkIT-------RNQMFEIDrkegkIFEFRKQr------------AKFCSE 99   Caenorhabditis...
EGT56786      38 PILHGIAWDEVIEERFVNKQCGFPACPRALpqRS-------KSQMYQIDkkegkIYEFCKQr------------NKFCTE 98  
CCF52538     139 LFLSSSSWGQILEERKLAGKCSYPPCSKPSpsAGa-----GGRGKFRISlrnksIKAVEDLdlgeagntwddvrDYFCSK 213 
EST05240     123 RILSSSSWGQVLEERHLAGHCAYPPCTNSAptTGr-----GGEGRFRISlgaksVKALEDVdlgeagntwddvrGVFCGK 197 
XP_012191123 616 LYLSASSWGQILEERKLAGKCSYPPCTNDSpsSAasglgrQREGKFRINlrtkqVKSREELelgqagntwdelrEFFCSK 695 
EOR02948      72 PLLSAASLARIEHERHLADLCAYPTCSNRPrgAYg-----SARDTLRIDrislsVYSQNSSt-----------dIAFCGS 135 
EKC99188     101 SYMHAGQYAEVEHERHLNGLCSYPLCSNPPaaPY------RAHKRFQISaraktIKEVEGNa-----------dEGFCSK 163 
Q5KAM5       114 SHFTPPQYLEITHERHLNSLCSYPVCPNPPyrPY------SSSRRFVIStrartIKPKEGNe-----------eEGYCSK 176  Cryptococcus n...
4M3O_A       115 AHFRCSQFYQFQLS 128  Kluyveromyces lactis NRRL Y-1140
CRZ24385     100 ECFFRSASVRTQLD 113 
P30641       100 MCYQKSSFVRKQLD 113  Caenorhabditis elegans
EGT56786      99 RCYQKYFFVREQLE 112 
CCF52538     214 SCYARSEWILRWVL 227 
EST05240     198 ACYARSEWVLRWVL 211 
XP_012191123 696 QCWARSEWILRWVL 709 
EOR02948     136 VCQQRAQWARTRCV 149 
EKC99188     164 KCRVKSQWVRENLG 177 
Q5KAM5       177 KCRARSGWVEGKLD 190  Cryptococcus neoformans
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