Conserved Protein Domain Family
Spexin

?
pfam15171: Spexin 
Neuropeptide secretory protein family, NPQ, spexin
Spexin, alternatively named NPQ, is a peptide hormone and is derived from a pro-hormone. This family of proteins has a role in inducing stomach wall contraction and is expressed in the submucosal layer of the mouse oesophagus and stomach. Spexin, like most peptide hormones, is a ligand for G-protein coupled receptors. Spexin is also thought to have a role in controlling arterial blood pressure as well as salt and water balance.
Statistics
?
PSSM-Id: 464543
Aligned: 6 rows
Threshold Bit Score: 110.018
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
ALD51527      27 APQAHFQRRNWTPQAMLYLKGAQGRRFISEESQRKDLYDRLQLETRSQNMSPLTLSEAAALFLSALRKaAQEegDEEEGE 106
XP_004052903  27 APQRLLERRNWTPQAMLYLKGAQGRRFISDQSRRKDLSDRPLPERRSPNPRLLTIPEAATILLASLQK-SPE--DEEKNF 103
Q0VC44        27 APQRLFERRNWTPQAMLYLKGAQGRRFLSDQSRRKDLSDRPPLERRSPNSQQLTLPEAAAVLLAFLQK-PQE--AGDENL 103 cattle
ALD51526      27 APQAHFQRRNWTPQAMLYLKGAQGRRFISDESQRKDLYGRMQLETRSQNTNPLSLSEAAALLLSSLWK-AQE--VEEENS 103
D3Z752        27 APQRLSEKRNWTPQAMLYLKGAQGRRFLSDQSRRKELADRPPPERRNPDLELLTLPEAAALFLASLEK-SQK--DEGGNF 103 house mouse
XP_013008402  27 APQRLLERRNWTPQAMLYLKGAQGRRFLSDQSRRKDLSDRLPPERRSPNPQLLPLPEAAALLLALLSK-PQE--DREEKF 103 domestic guinea...
ALD51527     107 EKPGYVSDGLLNW 119
XP_004052903 104 DQTRFLEDSLLNW 116
Q0VC44       104 DQTRFLEDSLLNW 116 cattle
ALD51526     104 DHPGYLMDNLSNR 116
D3Z752       104 DKSELLEDRLFNW 116 house mouse
XP_013008402 104 DRS---------- 106 domestic guinea pig
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap