Conserved Protein Domain Family
UBP12

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COG5560: UBP12 
Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 227847
Aligned: 4 rows
Threshold Bit Score: 1054.48
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
731045     57 IEDTESDASAVSsfASANELIAePHAasetnLGtngqdgrnvLEQQRDVVARlieENKETQKEGDKVCIVPKVWYDKFFD 136  baker's yeast
19074341    1 -------------------------------------------MMAEESLDQ---KPASSSGQCEYAVSFAFAKSQGMFR 34   Encephalitozoon c...
19076030   19 SLSEESQSSSNMddISQKSISLgDASeisknLPs--------IAEQKQLIGElvnNQPELELGQVDNYILSYSWYERLCS 90   fission yeast
19075499    1 MASTATQNASTR--YSQIWIDQ-PAS-----LP---------FQDSINLIKE---DKEKWKK-EKTAFLIDYDWFEGYVD 59   fission yeast
731045    137 PDVTDPEDIGPINTRMICR-DFENFVLEDYNRCPYLSIAEPVFNFLSEIYGMTSGSYPVVT--NLVINQTTGelETEYNK 213  baker's yeast
19074341   35 RASCIDGSSNPKVPGPRVDfVPESVWKSMRDGLFVSPACGADVQLQPRSTGKAVLITFMID--ELIPSASAP---GSSKS 109  Encephalitozoon c...
19076030   91 YLAEDGPFPGPVDQEDIADlETGTLKPDLQEEIDFTIISRDVWDLLVRWYGLKGPEFPRET--VNLGSESHPhlVVEVYP 168  fission yeast
19075499   60 FIYGEGDNPGPITQWRLLD-EKNELKHSLEESIDYSIVSASLWHMLVEWFGLEGLAIERKVllVGLAAEQKP--FVDIYP 136  fission yeast
731045    214 WFFRLHYLTEkQDGRKRRHG---------QddSIMYLSMSALNLVRDLVEKSMNLFFEKADhldvnavDFKIWFVSEGSD 284  baker's yeast
19074341  110 VVVKVGWIFS-ILQSLINLG------------DLVPHEAPSHGGGMRRSRRVVNAIVDPTD---------RLFDIVPEIM 167  Encephalitozoon c...
19076030  169 PIFSLTLLST--NAVDANES---------H--KPKKISLSSKSTLEDLLEGVKYTLSLPSD-------QFRLWRVDTDQP 228  fission yeast
19075499  137 INFTLHVLFDpINGENTSYSplyqidepyHsdEPYAFSFSRSDTLRSLYKQVMEAFQI-SDg-----tSFRLWYLNKSNL 210  fission yeast
731045    285 IATDSNVSTFLNSSYEITPLQFLELPIKKLLIPDMFENRLDKITSNPSDLVIEikpiegnHHWPSNYFAYn---KLepAs 361  baker's yeast
19074341  168 GLRLGLDEFMRRYRVLASDGRVLHPLARLDEFENRSVLKISKITRMPDGRVLS--------VDDHMRSIV----R----- 230  Encephalitozoon c...
19076030  229 LHRTIDPSSFIKINSKEIIDFLEKSKTLVELGMDSSCSLVAECMINETWPVDRalrlqflIQQRNNQSSNeeqkQEkrVp 308  fission yeast
19075499  211 SSRFVSLSEFNDQPAIALLSEYAVCMTIFEIDIADGSLLLEFQHPNGEWLSDS-------ITKEQNLTIN----KE--I- 276  fission yeast
731045    362 GTTGLVNLGNTCYMNSALQCLVHIPQLRDYFLYDGYEDEINEENPLGYHGYVARAFSDLVQKLFqnrmsiMQRNAAFPPS 441  baker's yeast
19074341  231 --G-LRNQGNTCFMNSGLQCLMNCWKLSEYFISREYEESLNR--HKAIHASLASAYYDLISQVY------DGNLHAITPV 299  Encephalitozoon c...
19076030  309 GTCGLSNLGNTCYMNSALQCLTHTRELRDFFTSDEWKNQVNESNPLGMGGQVASIFASLIKSLY------SPEHSSFAPR 382  fission yeast
19075499  277 GLCGLYNLGNSCYMNSALQCMIHTHELTKYFLSDSYEKDINYNNPLGMMGKVALSYASLLKMIHh-----TADMHSVSPS 351  fission yeast
731045    442 MFKSTIGHFNSMFSGYMQQDSQEFLAFLLDSLHEDLNRIIKKEYTEKPSLSPGDDVndwnVVKKLADDTWEMHLKRNCSV 521  baker's yeast
19074341  300 GIRKSLGSIYEEYKGNDEQDSVEFITKMLDTLHEALS-----TQSSHP--------------KKKEKEKWWEH---NRSI 357  Encephalitozoon c...
19076030  383 QFKATIGKFNHSFLGYGQQDSQEFLAFLLDGLHEDLNRIYQKPYTSKPDLYEVDEE----KIKNTAEECWRLHKLRNDSL 458  fission yeast
19075499  352 SFKFIIGEFNTYFSGYRQQDSQEFIAFFLDGLHEDLNRIQIKPYFERPDLFDEHPL----HVQRVANQCWDIHTKRNDSI 427  fission yeast
731045    522 ITDLFVGMYKSTLYCPECQNVSITFDPYNDVTLPLPVDTVWDKTIKIFPMNSPPLL--LEVELSKSSTYMDLKNYVGKMS 599  baker's yeast
19074341  358 ITDLFFFCLKSTLTCRGCGSTKVSIEPAVCLSLPIPRSMQHKDNIVVFYESGRRQP--VKIYADASTSIRGLKKLLDAEY 435  Encephalitozoon c...
19076030  459 IVDLFQGMYRSTLVCPVCNTVSITFDPFMDLTLPLPVKQVWSHTVTFIPADTNLTP--LAIEVVLESKAATIEDLVKYVA 536  fission yeast
19075499  428 IVQLFQGMYKSTLECSICYQKSTAFDPFMYLTLPLPTSAKWRHKVVYVPPFGTQSPveLYLELLMESTVIQMKFQATEKL 507  fission yeast
731045    600 GLDPntLFg-cEIFSNQIYVNYESTESNAQFLTLQELIKPADDVIFYElpvTNDNE---VIVPVLNT---RIEKG--YKN 670  baker's yeast
19074341  436 GVLG---------KVMCIWYDGNRNMLEPADDVVLQDIPQTLFCYEYS------ED---IEYCWVHL-----------KT 486  Encephalitozoon c...
19076030  537 EKSG--CSdyrKILVTETYKGRFYRFLTQLSKSLLMEISEEDEIYLYElerPYEDGsddILVPVYHIsddSTNSAnsYMS 614  fission yeast
19075499  508 QKMGleCG---ELTACDIYRGKVYKVLKNKDK-ISKKIHKWDHVVLYG---STANG---LTIPIVHGckrPAMPGs-YQS 576  fission yeast
731045    671 AMLFGVPFfITLKedeLNNPGAIRMKLqnrfvhlsggyipfpepvgnrtdfadafpllVEkypdvEFEQYkdiLQYTSIK 750  baker's yeast
19074341  487 KRLFMDKS-FKFN---ILIKASGYDGL----------------------------------------------LVLLEMK 516  Encephalitozoon c...
19076030  615 SRDFGHPFvLQLSdneVTDASFISEKLklkyqq-------------------fttlknLKnidslESLELgheDEQVQKG 675  fission yeast
19075499  577 NDVFGFP--LQLN---VRSRNVLTNDL-------------------------------VK-----EIVEL----YRVYAG 611  fission yeast
731045    751 VTDKDKSFFSIKIlsvekeqqfaSNNRTGPNFWtpisqlnLDKATDIDDKLEDvvkdiynysslvdcaegvlmQVDDEGd 830  baker's yeast
19074341  517 KTLACLVSEEVRC----------LLEESSISSY-------FKLENAGKTPREK--------------------------- 552  Encephalitozoon c...
19076030  676 PLDVDMDHSQTPLfemr---vfhDRFEKIPTGWnms-vsnLPLLTERDKKDLEstvdp-----------ldahSIEEEDd 740  fission yeast
19075499  612 -IDVAIGTLQLGL----------KRMESKAGKW--------ECIKEIEVKRFE--------------------IVEEEE- 651  fission yeast
731045    831 tegseAKNfskpfqsgddeenketvtNNENVNNTndrdedmeltddveedastepeltdkpealdkikdsltstpfails 910  baker's yeast
19074341  553 -----QMN------------------FPVAVVIS---------------------------------------------- 563  Encephalitozoon c...
19076030  741 sefkdVAPgsypepsksnentkltakENDRLLIQgdl------------------------------------------- 777  fission yeast
19075499  652 -----IVI-------------------DDKTVIM---------------------------------------------- 661  fission yeast
731045    911 mndiivCEWSELGSNEAFSddkiYnwenPATLPNKELENaklersnAkERTITLDDCLQLFSKPEILGLTDSWYCPTCKE 990  baker's yeast
19074341  564 ------RAHEGKRLLSLFH---------DPLGTIREIGA----------PKPTLQHCVNRFLEKEDLHPSERLHCEGCNG 618  Encephalitozoon c...
19076030  778 ----lvCEWPEKSYQFVFSvapsSpqmgRSLWLESKTILsdkkddsEdSRTITLNDCLDEFEKTEQLGEEDPWYCPTCKE 853  fission yeast
19075499  662 ------CLWNDQQYEKLF-----Y----NCEWIFEKIQF-------H-MESITLEDCLLEFSKPEQLDLQDSWYCPGCKA 718  fission yeast
731045    991 HRQATKQIQLWNTPDILLIHLKRFE---SQRSFSDKIDATVNFPITDLDLSRYVVYK------DDPRg-LIYDLYAVDNH 1060 baker's yeast
19074341  619 KMMFSKKMDLEDLPMYLIIQLKRFQ---YVNSSPMKISTLIEYPLDKFLLNGVEYMV------------IGVCNHDSD-- 681  Encephalitozoon c...
19076030  854 FRQASKQMEIWRCPEILIFHLKRFS---SERRFRDKIDDLVEFPIDNLDMSMRTGSYkls-ekENPK--LIYELYAVDNH 927  fission yeast
19075499  719 FRPATKRLEIWRLPKILVIHLNRFSghgGDLRRRRKRRDLVVYPVFDLNLKQFLSPFikdhewLSSQksMLYDLYAVDNH 798  fission yeast
731045   1061 YGGLGGGHYTAYVKNFADNKWYYFDDSRVTETAPENSIAGSAYLLFYIRRH 1111 baker's yeast
19074341  682 -AVTSSGHYVSYLRK--N-GWYLCNDQKIERVDEVD--KEHTYVLFLERCS 726  Encephalitozoon cuniculi
19076030  928 YGGLGGGHYTAFAKNPDNGQFYCFDDSRVTPVCPEETVTSAAYLLFYRRKT 978  fission yeast
19075499  799 HGFMSNGHYTAYARDASSQTFFKFDDTAICEIDPEDIVTSSAYVLFYRAKN 849  fission yeast
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