7F73


Conserved Protein Domain Family
TMPIT

?
pfam07851: TMPIT 
TMPIT-like protein
A number of members of this family are annotated as being transmembrane proteins induced by tumour necrosis factor alpha, but no literature was found to support this.
Statistics
?
PSSM-Id: 462288
Aligned: 40 rows
Threshold Bit Score: 299.506
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
7F73_A       291 EREWHELEGEFQELQETHriykq-kleelAALQTLCSSSISKQKKHLKDLKLTLQRCKRHAS-------------REEAE 356
EFC40706       9 NEDWSECSTDQEKIESSFdklikekradlFYSESDVKKKAEKQKKRLRSCVAMIESVEKAg--------------SSNEE 74 
XP_001783309  23 EDRVASLAKSCRSLKEAA-----------SAHSSRWQHEADTLSKQAINHVSTLKKLQVDVGsas-------ekdEIDQQ 84 
ERN08213      11 LEEVSHLLDRAKELQDSA-----------SSFLSKMKHEEQSILQRVSALQSDLKKLQACVAsas-------aseTLDKR 72 
XP_002518967  14 EEEVERVVEQAKQVQEAA-----------ASLISRSTNDEQSLRQRALSLESSIRRCRSLFDsll-------srnLIHPK 75 
Q93XX0         4 EEEVKQIIDEVKELHDSA-----------ASFISSSSQQELSLRQKASAVDSSIRRLHSTIVsn----------kNLDPK 62  thale cress
XP_004352427  16 KKELEELEKSQNGVKEKGlkfke-qiavgFKSLDEICNTLDKQEKESSKLLQRITLLQSGGG-------------DKSND 81 
Q54IK2        34 KNEVFELKKSHEQCKEKGikvkk-dindvFKHADDITNTLAKHEKESSQLISRIKHLNAK---------------EKQLD 97  Dictyostelium d...
EGC34020      31 KNEILELKRSNLSCQEKGikikk-eindvYKQVDDIAGTLAKHEKESSHLQSRLKQILTK---------------EKQID 94 
XP_018674989   8 LEEAARLAEAARELQEAA-----------AILISRTRNEEQSLRQRAVALESDLRRLQSSLDstvrkkgqsatggGVDPK 76  wild Malaysian ...
7F73_A       357 --LVQQMAANIKERQDVFF--DMEAYLPKK-NGLYLNLVLG-NVNVTLLSNQA-KFAYKDEYEKFKLYLTIILLLGAVAC 429
EFC40706      75 --LIKDLQEKKLKIKHYIKklDVINKQTLNtGGKFVELFLGkESSAVLVGDDSkKFNFKKEYESFKYKCTVWNIPFTLLL 152
XP_001783309  85 --TADKLEEELYRARTMLYngEVSSLLPAKaNGVFLRMLLG-PTNVRATLKDG-RYKVKEEYNAYRDRTALMFLAFPVIL 160
ERN08213      73 --EAEKLEEELSRAKCMIAdgDVSSLLPSKsNGKFLRMFLG-PISVRATRKDV-QLKVKEEYNNYRDRTAVMFLLFPFAL 148
XP_002518967  76 --LADKLDEDLQRARCMMVdgDAAAFLPSKaQGGFLKMFLG-PINVRASRKDV-QLKVKEEYNSYRDRTALLFLLFPSLL 151
Q93XX0        63 --LVEKLEEDLHRARCMLVdgETSSFLPSKpQGRFVRMFCG-PVNVRALRKDV-QLKVKEEYNRYRDKTALLFLFFPATL 138 thale cress
XP_004352427  82 --AVVEMKQKIQSIKTSIK--QSKKTFTPEtGGVFVRLFLG-QVNVKHYREGE-RFRLKTEYEKFKFKTNPQFILFVALL 155
Q54IK2        98 --ITKELSAHLDQIKVNVK--RAKVSFTPEtGSIFVRLFLG-QVNVKHMRENE-KFRLKQEYEKFKKKTNPQFILFVVLL 171 Dictyostelium d...
EGC34020      95 nnIIKELTDDLEQIKMNVK--RSKGLFTPEtGSIFVRLFLG-QVNVKHLRENE-KFRLKTEYEKFKKKTNPQFIIFVVLL 170
XP_018674989  77 --IAEKVDEELCRARCVINdgDVASLLLSKtHGRFLKMFLG-PVNVRATRKEV-QLKVKEEYNSYRDRTAFLFLLFPSTL 152 wild Malaysian ...
7F73_A       430 RFVLHYR---VTDE----VFNFLLVWYYCTLTIRESILISNGSRIKGWWVSHHYVSTFLSGVMLTW-----PNGPIYQKF 497
EFC40706     153 YFFIQSR---AIDT----LYQLYLTYFYLTLALRENILAVNGSNIKAWWIRHHYLSIFLVITMLTW-----PETAFYQAY 220
XP_001783309 161 LVLKNKIwngCFPAlpvqVYQAWLLFFYTSLALRENILRVNGSDIRPWWVYHHYCAMVMALVSLTWg---hPSCIRKQQG 237
ERN08213     149 LILRYAIwkgCFPAwavqLYQAWLLFLYTSLALRENILRINGSDIRPWWIYHHYCAMMMALVSLTWeikgqPDCYQKQRG 228
XP_002518967 152 LILRSWLwdgCLPAfpvqLYQAWLLFLYTGLALRENILRSNGSDIRPWWIYHHYCAMVMALVSLTWeikgqPNCAQKQRG 231
Q93XX0       139 LILRSYYwggCLPAfpvqLYEAWLLFLYAGLAMRENILRANGSDIRPWWLYHHYCAMAMALVSLTWeikgqPNCVQKQRG 218 thale cress
XP_004352427 156 FMFPSNS---FITT----SWQIWLLYYYVTLALRENILLVNGSSIRPWWIMHHYLSIAGALTNLLW-----PLSTSFTDL 223
Q54IK2       172 LLYPQSS---FVTT----SWQIWLLYYYITLALRENILLVNGSSIKPWWIMHHYLSIAGSLTNLLF-----PLSESFSYF 239 Dictyostelium d...
EGC34020     171 LLYPHSS---FVTT----SWQIWLLYYYITLALRENILLVNGSSIKPWWIMHHYLSIAGSLTNLLF-----PFSEAFTYF 238
XP_018674989 153 LLLRSWVwdaCLPAlpvqLYQVWLLYLYTTLALRENILRVNGSDIRPWWICHHYCAMLMALISLTWeikrqPDCAYKQRG 232 wild Malaysian ...
7F73_A       498 RNQFLAFSIFQSCVQFLQYYYQRGCLYRLRALGERNHLDLTveg-----fqsWM----WRG-LTFLLPFLFCGHFWQLYN 567
EFC40706     221 RPYFLLYALYASIVQVLQYKYQKERLYVRTAIGKSNMMDVAnsd------ssQVvvesSLA-LVFLLPFIFIGQIFQVYN 293
XP_001783309 238 VQLFLGWAVMQGVAMLLQNRYQRRRLYTRIALGKAGRMDVV-----------WGetagVKGqLGILYPLLFILQGFQFFI 306
ERN08213     229 IELFLTWAMMQGVAMLLQNRYQRQRLYTRIALGKANRMDVV-----------WGetasVEGqLWLLYPVLFILQGFEAYI 297
XP_002518967 232 VQLFLQWAMMQGVAMLLQNRYQRQRLYTRIALGKAKRMDVV-----------WGetagVDGqLWLLCPILFILQGFEAYV 300
Q93XX0       219 VHLFLQWAMMQGVAMLLQNRYQRQRLYTRIALGKAKRMDVV-----------WGetagVDGqLWLLCPILFILQVFEAYV 287 thale cress
XP_004352427 224 LPMMTMFSGAQGIVQILTNRYQQGQLYRMVAIGKANIMDVTsenmi--sdpgW-----TPS-ALFLLPFLLFVHCFQMYN 295
Q54IK2       240 LPQVTYFSGCQGLVQILTNRYQQGRLYKLVAMGKANIIDVTgesegwgndpgW-----TPS-ALFLFPFLLFVQFFQLYN 313 Dictyostelium d...
EGC34020     239 LPQVTYFSGCQGLVQILTNRYQQGRLYKLVAMGKANIIDVTgesegwnndpgW-----TPS-AMFLLPFLLFVQFFQLYN 312
XP_018674989 233 VQLFLMWAMMQGVSMLLQNRYQRQRLYTRIALGKAKRMDVV-----------WGetagVEGqLWLLCPILFILQGFEAYV 301 wild Malaysian ...
7F73_A       568 AVTLFELSSH-EECR-----EWQVFVLAFTFLILFLGNFLTTLKVVHAKLQKN 614
EFC40706     294 AYKLFDWGLLhPESFggitvEWQVYANGLLFLILALGNFVTTTEVLVKKVKRV 346
XP_001783309 307 GILLLKTAIV-EDKS-----EWQIVVCGLLLVLMACGNFINTVATLVAKAKIK 353
ERN08213     298 GILLLMTAVT-SSVS-----EWQVVVCGGLLVIMASGNFANTVQTLSAKLRFK 344
XP_002518967 301 GLQLLRTAFV-RVVS-----EWQVIFCGMLLVFMAVGNFFNTVQTLMVKSRFK 347
Q93XX0       288 GLLLLRKTVT-GVVN-----EWQVMVCGILLVVMAVGNFINTVETLMAKSRVK 334 thale cress
XP_004352427 296 GFVFLTYSYFkYHTYy---iEWQVIACGLILVSLGIGNLVTTSNIYLNKWKSY 345
Q54IK2       314 SFSFFAFAYQrSGYV-----EWQVFSCGFIFLCLGLGNLLTTLSVYYQKWKNF 361 Dictyostelium discoideum
EGC34020     313 SFSFFYFAYQrDGNV-----EWQVYMCGLIFLLLGFGNLFTTISVYYQKWKNI 360
XP_018674989 302 GLLLLRTAFV-GVIC-----EWQVIACGILLVLMAIGNFANTMQTLIAKSRFK 348 wild Malaysian banana
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap