Conserved Protein Domain Family
FGF-BP1

?
pfam06473: FGF-BP1 
FGF binding protein 1 (FGF-BP1)
This family consists of several mammalian FGF binding protein 1. Fibroblast growth factors (FGFs) play important roles during fetal and embryonic development. Fibroblast growth factor-binding protein (FGF-BP) 1 is a secreted protein that can bind fibroblast growth factors (FGFs) 1 and 2.
Statistics
?
PSSM-Id: 461927
Aligned: 38 rows
Threshold Bit Score: 177.559
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_007230364   5 CSTVLLLACCVWVIHAQAQSSQSVANQDnsnqanvhanestpslpskAKQEPQQPNSVWDEPIRFSSKAKDSCTLVISG- 83 
XP_012910191   7 LLLLLLGGCLLVAARRAKGTAGSAAELA--------------------------SGPTGGSSGRFVSPERHACSWQLlpr 60 
XP_006926013  10 LSLLLLSGCLLATAQRDKGVGGSAAESA--------------------------WGHTGGSSGRFVSPERHTCSWQLllp 63 
Q8TAT2        13 SLLLLLSGCLLAAARREKGAASNVAEPV--------------------------PGPTGGSSGRFLSPEQHACSWQLllp 66  human
Q1HCM0        14 TLLLLLGGCLLSAAGRDKGAAGREVTRA--------------------------SRPTVGSSGRFVSPEQHACSWQLlvp 67  house mouse
XP_003783746  11 SLLLLLGGCFLAAGRRDQGAAGSAVEPV-------------------------PPGPRGGSSGRFISPEQHACSWQLllp 65 
XP_005991629   6 ALLTVLLFHCLCSLQEVGAKKEK-------------------------QAGKRGKIK-FPTSGEFITKDSHACTWEISG- 58 
XP_015201750   3 LLCVLAFVLCLYGLPGTEGKRDSRNSTQ---------------------LAKKGRSKSVPSSGELITKDSHRCTWEASG- 60 
XP_003455729   8 VLILLLLIPILTEAKRQPGQEKPDKPRQpp---------------psPQPAKRPRNRSVPGSGELTSKEGHRCVWQTSG- 71 
XP_005806167   7 CCVFLLCLVFLAEAKRTPGQDKRDKPRQpq---------------ssPPPARRSRNRSVLSSGELSTKQGHRCTWQTSG- 70 
XP_007230364  84 ---QgDFTKLRVSCKNK----GKSYWCDFLGKPNLCRPYnKNPRHYFTQVMWELRKLPNACQGPRVYKPQMC--RTAGDE 154
XP_012910191  61 vpgpaAGSELALSCRDPa---GALQQCAYRGEPERCAAYvARGPHYWKQVLGGLRKKRRPCQDPAPLKARLCagKKGH-G 136
XP_006926013  64 apgqvVGSELALLCQGPd---GARQHCAYRGEPERCAAYaTRGSLYWKQVLGRLRKKPRPCQDPAPLKARLCagKKGH-R 139
Q8TAT2        67 apeaaAGSELALRCQSPd---GARHQCAYRGHPERCAAYaARRAHFWKQVLGGLRKKRRPCHDPAPLQARLCagKKGH-G 142 human
Q1HCM0        68 apgtpTGGELALRCQTPg---GASLHCAYRGHPERCAATgARRAHYWRRLLGALRRRPRPCLDPAPLPPRLCa-RKTA-G 142 house mouse
XP_003783746  66 tpgaaEGSELALRCQGPd---GARHQCAYRGEPERCATYtARRSHYWKQVLGALRKKRRPCHDPSPLQARLCagKKGH-G 141
XP_005991629  59 ---D-EEISLLVICPQQ----DNNYWCKYTGQPHQCLSYnTRTSQYWKQILGKLKKKKNACE-DKTLKSRIC--KRGPTE 127
XP_015201750  61 ---E-GEVTLLINCNHQ----DQTYWCQYLGKPTLCPVYnSKSSQYWKQVVSKLKKKKNPCEGDKILKTRLC--KKSPVE 130
XP_003455729  72 ---E-GLVSLLVNCSIEtqgdLQRYWCRYAGKPDLCQAYgVKSSQYWKQLVGKLKKRQNACEGEKVLKAKTC--KKAPAE 145
XP_005806167  71 ---E-GLVSLVVNCSTEsegdAERYWCRYAGKPNLCQAYsMKSSQYWKQLVGKLKKRENACEGEKVLKAKTC--KKAPGE 144
XP_007230364 155 AQMVFHNSwp-----ktTTSAPVTAPQDRSQSQPKQPQPpktsat--------pkpptAAKAVPKTPKQp-TKPVLPRKP 220
XP_012910191 137 AELRLVPHgsspvrptaAVFPRDPEPPARSRGRLREPAPgpaggsrlpesksprgkpsE-KTKAGKRKA--TSDPEEERP 213
XP_006926013 140 AELRLVPHafppagptaAGYLRDLKPRARSWGRPQEPAIrpaarvpplpssppkgkpsKKKTKGGKRKA--ASAAVEERP 217
Q8TAT2       143 AELRLVPRaspparptvAGFAGESKPRARNRGRTRERASgpaagtpppqsappkenpsERKTNEGKRKA--ALVPNEERP 220 human
Q1HCM0       143 SDLHSPAHpslp-----arpSEPPRSRARSPARSRQSVRspssqp--------ekkplLVKSNSGGRKA--GSDPVPEPP 207 house mouse
XP_003783746 142 AELRLVSGasqpahptpAGFPGEPKPRARSRGRSREHAAglaps----------vrpkEKKTKGDKRKA--ASDPHEERP 209
XP_005991629 128 AHLRLVEK---------SFSSG-KEERGKSKASGRKKDSektaveskd--elvntgvsEKRGKTGKRKSkpYPTSAKQAE 195
XP_015201750 131 SHMKLSEK---------SSADARAEDSAKGKGGGRKKEAa---------------------pEVADRKKekKPPVAEK-- 178
XP_003455729 146 AHMKLAQR---------SGEDDKKGGKEGGKKKPAGKSVggg--------------rmdKRKKKEEETE--EKKKRREER 200
XP_005806167 145 AHMKLAQR---------SG----EEDKNAAKEGGKKKGEaga--------------ksSDGGKVEKRKKkvKEDEAEKKK 197
XP_007230364 221 SKTTta-kpTTEpENRATKLAEEYCWSGIQNVCAYFIGWFLN 261
XP_012910191 214 LGTRp----DPDgLDENAKLTETYCAEKWHSLCNFFVNFWNG 251
XP_006926013 218 LGTRp----DPDgLDENAKLTETYCAEKWHSLCNFFVNFWNG 255
Q8TAT2       221 MGTGp----DPDgLDGNAELTETYCAEKWHSLCNFFVNFWNG 258 human
Q1HCM0       208 AAAGf----QPNgLDQNAELTETYCTEKWHSLCNFFVNFWNG 245 house mouse
XP_003783746 210 MGTGp----YADaLDENTELTKTYCAEKWHSLCNFFVNFWNG 247
XP_005991629 196 ATTSpagevNDDdSEFNEDLAEAYCAEKWHSLCSFFVNLWNG 237
XP_015201750 179 ---EdfgevNDEnAESEMEPVENYCADGWHSLCNFFVKLFDG 217
XP_003455729 201 TEAEd----EEG-MQSDMEPVQAYCSEGWHSVCSFFVKFFEG 237
XP_005806167 198 R--EertefDDEgMVNDMEPVQTYCSDGWHSVCSFFVKFFEG 237
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap