Conserved Protein Domain Family
Tsc35

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pfam15079: Tsc35 
Testis-specific protein 35
Tsc35 (also referred to in the literature as Tsc24) is essential for spermatogenesis in mammalian male reproduction. It is expressed in the testis from day 35 onwards in mice.
Statistics
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PSSM-Id: 464490
Aligned: 9 rows
Threshold Bit Score: 271.715
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_019651914   1 MSAKKAELKKASL--------SKNYKAVCLELKPEPTK------------------------------------TYDYKG 36 
XP_023609794   1 MSAKKAELKKANL--------SKNYKAICLELKPEPIK------------------------------------TCEYKR 36 
XP_019831562   1 MSAKRVEPKKTSL--------SKNYRAVCLELKPEPIK------------------------------------TYDYKG 36 
Q5T0J7         1 MSAKRAELKKTHL--------SKNYKAVCLELKPEPTK------------------------------------TFDYKA 36  human
XP_017460128   1 MSAKR----KTNL--------KKSYKAVCMELKPELTQ------------------------------------IYDVKG 32 
Q14BK3         1 MSAKNAELKKTNL--------KKNYKAVCME--PKLTQ------------------------------------IYDFKG 34  house mouse
XP_003474679   1 M-AKRADLKKTILvkeehcwmNKNYKAVCPKLKPETTK------------------------------------TYNFKE 43  domestic guinea...
XP_003785860   1 MSAKRAEPKKANL--------SETYKAICLELKPEPTIlrsvfeampparpeirgeviwsqgsiaisgsqdlsqTCTYKG 72  small-eared galago
XP_023405005   1 --------midrltsncfslqSKNYKTACLELKAEPTK------------------------------------TYDYKG 36  African savanna...
XP_019651914  37 VKQEGPFTKPGGTHELRNELREVREELKEKMDEIKQIKGVMDKDFDKLQEFVEIMKEMQRDMDEKMDVLVNIQKNSKLPL 116
XP_023609794  37 IKPEGPFTKTGGTRELKNDLREVREELKEKMEEIKQIKCVMDKDFDKLQEFVEIMKEMQKDMDEKMDVLINIQKNSKLPL 116
XP_019831562  37 AKQEGPFTKPGGTKELKNELREVREELKEKMEEIKQIKDVMDKDFDKLQEFVEIMKEMQKDMDEKMDVLINIQKNSKFPL 116
Q5T0J7        37 VKQEGRFTKAGVTQDLKNELREVREELKEKMEEIKQIKDLMDKDFDKLHEFVEIMKEMQKDMDEKMDILINTQKNYKLPL 116 human
XP_017460128  33 LKQEGLCIRKGMTQELKNGLREVREELTEKIEEIKQIKNLMDKDFDKLHEFVEIMKEMQQDMDEKMDVLINIQQNNKLPF 112
Q14BK3        35 FKQEGLLIRKGMTRELKNELREVREQLTEKMEEIKQIKDIMDKDFDKLYEFVEIMKEMQQDMDEKMDVLINNQKNNKLPF 114 house mouse
XP_003474679  44 VQHKGPFAKTGMTQELKNELREVREELKEKMEEIKQIKDIMDKDFDKLHEFVEIMKEMQKDMDEKMDVLINIQKDNKLPL 123 domestic guinea...
XP_003785860  73 VKQEGLPTKTGVTRELKNELREVREELQEKMEEIKQIKTIMDRDFDKLHEFVEIMKEMQKDMDEKMDVLINIQKNNQHPL 152 small-eared galago
XP_023405005  37 VKQEGPTTKIGGTKELKNELREVREELKEKMEEIKQIKDIMDKDFDKLKEFVEIMKDMQKDMDEKMDVLMNIQKSNKVPL 116 African savanna...
XP_019651914 117 RRGPKEQ-QELRLVGKTDTDPQLRLKKVDGA---DGTPLSLHKKMMALQKTKKDPLDSLHQCGPCCEKCLLCALKNSYNQ 192
XP_023609794 117 RRGPKEH-QELRQIGKSDTDSQHRLKKLEGV---EGASLSIHKKNMALQKLKKDPLDSLHQRGTCYEKCMLCALKNNHNQ 192
XP_019831562 117 RRGLKMQ-QELRLIGKTDTEPQLRLRKMDGA---GGAPLSLHKKMVARQQPK-DPMDPLHQCDSCFEKCLLCTPQNNYDR 191
Q5T0J7       117 RRAPKEQ-QELRLMGKTHREPQLRPKKMDGAsgvNGAPCALHKKTMAPQKTKQGSLDPLHHCGTCCEKCLLCALKNNYNR 195 human
XP_017460128 113 QNQPKEQ-QKFRKRGKMGKNSQVIIMEES-----DEVSLASE-KMVVLPKTTNNPMDPLH----ACEKCLLCALKTTCNQ 181
Q14BK3       115 QNQAKEQ-QKFWQLGKMDKSSQAMITEEP-----DGVPLACD-KNVVPPKPTRNPLESLHPCQSCCEKCLLCALKTNRNQ 187 house mouse
XP_003474679 124 QRGSRDH-HDHRLMGMTDIDPQLRLKRVDRA---NRTSLPLH-KMMEPQKPKKDPMDSVHQCRSCCEKCMLCALKTNYNQ 198 domestic guinea...
XP_003785860 153 RKGPKEElQELGLMGKSNTDPQLRLKKMDGA---DGAPSALPKKTLASQKPKKEPLDPRHPCRTCCEKCLLCALKNNYNQ 229 small-eared galago
XP_023405005 117 RKRPKEQ-QELRSMEKTDSDPPFRLNRMDKV---DRAPSVRLRKIMAPQKVKQDTLDSIH-CRTCetstpglgtfltldi 191 African savanna...
XP_019651914 193 GsrKLPYQAWPPFSS 207
XP_023609794 193 G--RLPHRGWAPSSS 205
XP_019831562 192 G--KLPYHAWASFSP 204
Q5T0J7       196 G--NIPSEASGLYKG 208 human
XP_017460128 182 G--RPSHHAWAPFSP 194
Q14BK3       188 G--RPSHHAWVPFSP 200 house mouse
XP_003474679 199 G-------------- 199 domestic guinea pig
XP_003785860 230 Avplkeascplaans 244 small-eared galago
XP_023405005 192 qcclliqlyfnssat 206 African savanna elephant
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