Conserved Protein Domain Family
CCDC144C

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pfam14915: CCDC144C 
CCDC144C protein coiled-coil region
This family includes the human protein CCDC144C and the ankyrin repeat domain-containing protein 26-like 1 found in eukaryotes. Its function remains unknown, however, it is known to contain a coiled-coil domain which corresponds to this region. The ankyrin repeat which features in this protein is a common amino acid motif.
Statistics
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PSSM-Id: 464371
Aligned: 32 rows
Threshold Bit Score: 301.521
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGW08323      904 NQRLQDEIAMLRLEMDTVKTHSQEKEKKYLEDIKTANEKSDKLQRMIKLNEETftktIFQYNGQINNLTtENTMLSSKLE 983 
XP_007668847  903 NQKLQEEIAILKLEVDTARVQNQEKESRYVDENEALKEKNEDLQKELKLNEEAltkrMFQYNGQLTVLTaENAMLRSQME 982 
XP_012815407 1382 NSNLQEEMNVLKLELDHVRSQNQQEESKYMDENENLKEKIADLRRDLKMNEETltqtVIQYNSQLHALKtENTMLCSKLE 1461
XP_014349263 1192 NRTLQEEMLVFKLELDRVRARNQEEESLHLEEKEMLKEKVEDLKGELKLSEEAltqtVFQYNGQLNTLKtESAMLNSRFE 1271
XP_015207761 1870 NRSLQDEVAMLKLDLDRAKAHNQQEEAKYSEENEALKEKVEDLKRDLKLNEEAlaqtVFQYNSQLSALKtECSVITSKLE 1949
XP_022527643 2121 VCTLQEELSCVRAELDRSHCHSQQEESRLSEERDALRERLEDARRDLKLNEEAltqtVFQYNGQLSALKaECSVVSAKLE 2200
3_pfamImport    1 SVTLQDQLTTLRSDHERLRANSSLKESHLSDENEALKEQLEDVRRDLKLNSEAltqtVFNCNNQVTTLKsELAMATSRLE 80  
XP_025764799 1510 TASLQEQLTILRTDSERLQTQSSLNESHLIEAREILKEELEEVRRESQLNNETmaqvVFNYKNQVTTLKsELAITTTRLE 1589
CAF98417      102 IATLQEQLTTSKRDLEHSCANSSLRECTLSEENRVLKDQLEDARRDLKLNSESlkntVFNSNNEVSSLKsELSETRTRLE 181 
XP_008109382 1371 NQILQDELSVLRLELDRIRIQHQEQESKYLEENEALKEKIEEL----KLNEDAltqtVFQCNGQINISKtEAAMLTTKLE 1446
EGW08323      984 NEKQNKERLETDIESFRSRLASAMHDHAeIQTSKRDLEIAFQRARDEWVRLQDKMNFDMSNLRDNNEILSQQLSKTEKKL 1063
XP_007668847  983 NEKQNKDRLETEMESYRSRLSTAIQEHEkSQVAKSDAERKFQRERDEWLRLQDKLNHDLSNLRDTNGVLSQHLSQAESKA 1062
XP_012815407 1462 HEKQGKDRLETELESIRSRLTSTLQEVErNQALKIEVERTLQRERDEWLRSQDKLNHELSTIRENNNNLSQQLIRAETKS 1541
XP_014349263 1272 HEKQSKEKLETEVESVRSRLTSALQEVErCQAAKSDAERTLQRECDEWLRLQEKRDREISSLRETIDRLSQKLSKVETKA 1351
XP_015207761 1950 HEKQAKDKLETELESVRIRLTSALQEVErSQAAKADLERTLQRERDEWLRLQEKHNSEATSQRESINSLSQQLGKAEAKA 2029
XP_022527643 2201 HERQTRQQLEAEAEASRARLQAALQETErCQALRTEAERALQRERDEHQRAQDKRSMESGSQRDTIQSLSQKLSKAEARA 2280
3_pfamImport   81 IERQTRETLDSEVESARIRLAGAVKQAElSMAAHTDLERVLLREKEEHQRFKDRITGEAASQREAITSLSQKLARAESGA 160 
XP_025764799 1590 NERQIRDKLEEEVELTRTRLAGAVKDAEhCLASKSETEKALLREKEEHQRLKDRLAGEAASQREEVSTLSQKLAKAESHA 1669
CAF98417      182 NERYTCERLETELESIRTRLSGAEKEAErSHVAKSERESTLLREKEEHQHLKGKLTGEVAILREENSTLSQKLIKAEAQA 261 
XP_008109382 1447 HIKEHKERLEMEINSFHSRLNSTAQELErCQLGKNDAERVLQRERDEWIRLKDKLNHDICTLREASNTMSQQLSKSESKA 1526
EGW08323     1064 NSLEIEFHHTKDALREKTLALKHVQRDLNQTQCQMKEVEHMYQDEQGKVNKYMGKQESIEERLSQLQSENMLLRQQLDDA 1143
XP_007668847 1063 NGLENELHRLRDIIREKSLSLESAQRDLQQTQCQAKELERVCQNEKAQMTKFTVKQESMTERLAQLQSENALLRQQLEDA 1142
XP_012815407 1542 NSLENELRQTNTSLQDKVILSESTQRELTHTCGRIKELEHTLQLEKDKICKSTVKQESLQEKLAQIQSENMLLRQQIEDV 1621
XP_014349263 1352 NGLENELHCATLSVTEKTLLLESSQRDLHQSQSRIKELEHSLQAEKDQLSKHVARQESMHERLAQFQSETTLLRQQLEDA 1431
XP_015207761 2030 NSLENECHRATLSLTEKVLLLETMQREKEQAQSRQKELEASLQAEKDQMSKSLFRQETMQERLVQVQSENMLLRQQLEEA 2109
XP_022527643 2281 NSLENECHRTALSVTEKGVLLETVMREREQAQARLKELEAALQSEREQSTRTSARHEAVQERLAQAQSEAALLRQQLEEA 2360
3_pfamImport  161 NSMENEVHRATLQLTEKSLLLEVLQREKDQGAARIKELESALQSEREQIGRVGARQEAAQERLAQTQSEGMLLRQQLEEA 240 
XP_025764799 1670 NSMENEVHRTTMQLTEKGVLLEVLQREKDQAVAHVKELEKALQTHREEVSCNKACQEATKERLVQAQSEAMLLRQQLEEA 1749
CAF98417      262 NNLENEAHRVTQQLKDKGLLQEVLQREKEQAVTRGLELEKTLHAEREQFSRDRARHEATQERLTQAQSEVMLLRQQLEEA 341 
XP_008109382 1527 NGLENELHQVTYTLREKSLLLESCQRDLNQAQGQVKELENARQAEKDQMNKYIVKHDSMQERLAQLQSENLLLRQQLEDF 1606
EGW08323     1144 SNKADSKDKTIVDIQDQFHDMLSRLQAESQKHRLLLEDRNKELVSECSHLKERMCQYENEKAER 1207
XP_007668847 1143 QNKGIVQDKVVNDVQVLFRDIVDKLHAESDKQILLVEERNKELTCKCSHLREQLYKSETQQADR 1206
XP_012815407 1622 NNKGIIKDKTVSDVQDKFTEIIAKIRADAERQVQIIEERNKDLIIKYNETREQLYRLETEKVER 1685
XP_014349263 1432 QNKGIIKEKVVSDVQDRFSDIYTKLREDSEKQVRMVEERNKELNIKNNDLREQVYKYETEKTER 1495
XP_015207761 2110 QNKGIIKEKVVTDVQDRFSDILTKLRADSEERVHMVEERSKELVAKNIELREQIYKHENEKSER 2173
XP_022527643 2361 NNKGTAKERAATDAQERFADVLNQLRADGEERVQLVEERSKELATKNAELREQNYKLEQEKGER 2424
3_pfamImport  241 QNKGVAKERAVTDAQERFSDILAQLRSDSEERVQLVEERSKELASKAADLRDQIYRLEEEKNER 304 
XP_025764799 1750 QNKGAAKERAVTDAQERFSDILSKLRSDCEERVQLLEDRNKELASKAVDLRDQVYKLEEDKNER 1813
CAF98417      342 QNKGLAKERAVTDAQGHLKDILSKLQSDYEERVQLVKERNKELDSKANDLQDHIHKLQDEKNEI 405 
XP_008109382 1607 QNKSIIKEKVVTDVQDRFNDIFSKLRSDTEKQVQLMEERNKELVTKCDNQREQVLKYEAEKADR 1670
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