Conserved Protein Domain Family
Lung_7-TM_R

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pfam06814: Lung_7-TM_R 
Lung seven transmembrane receptor
This family represents a conserved region with eukaryotic lung seven transmembrane receptors and related proteins.
Statistics
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PSSM-Id: 369089
Aligned: 14 rows
Threshold Bit Score: 256.482
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002596415 319 EEEGLYNLRfhncynkhsvedSKSKVTISMQVDVVEMNNDNYLSAGEVPLPPVYLTMMGVFFLTGCLWIHILRKRKGDVF 398
Q9Y7Y9       136 SQSGYYCIW------------SHSKKMLPYQALVNWQNAYGGLPASQFPRMPISGGITIAYSVILALWMFFRFQYKHSIV 203 Schizosaccharom...
P32857       157 KETGFYCVTa-----------fRSSTSTKFNAVVNFRNAYGQLAGTEINKLPLYGLLAVAYVVAMALYSFAFWKHKHELL 225 Saccharomyces c...
P38745       152 NKTGYYCVTt----------sSFISSSSKFKATVNFRNAYGQLDASEAYKMPIYAFLAVAYAVCTLVYSWLCWKHRHELL 221 Saccharomyces c...
O13989       141 EQSGLYCVFtap----------leGSSEAYKITVTWENYFGNLDATDYPHLFLNPILLAINCLIGIWWSFIMFRYRHDLL 210 Schizosaccharom...
Q8BUV8       214 DQEGLYSLYfhkcsg-nnvkpGEQASFS-LNIAITEKNPNSYLSAGEIPLPKLYVSMALFFFLSGTIWIHILRKRRNDVF 291 house mouse
Q22938       169 PRDGIYYMIikvvg---ksfpSSPNSNTNVTISVQWKAPYGYLSAIDWPLLRFYKIMCVFYSALALIWVYCCIKYYRDIL 245 Caenorhabditis ...
Q9VQ34       160 KEDGIYEIEvn--------iaAGPSAQFSAVVHIEFLGPHGFISAIDWPFLPFYLIMCIVYVIFGIIWLFVSFAQWRDLL 231 fruit fly
Q8BKU8       175 QKDGFHIFIvsik-------tekTDAVWDLNVSLSMVGPHGYISASDWPLMIFYMVMCIVYILYGVLWLLWSACYWKDIL 247 house mouse
O04088       179 KKTGLYTVYfmtc--------dpelDGATIRGRTVWKNRGGYLQGEKAPLKKFYASMLLAYVVLGLVWFPQVAQYWKDGI 250 thale cress
XP_002596415 399 KIHYLMAALVMVKAMSLMFHAVNYHFIAVEGSP---EEAWAVLYYIVYLTRSLLLLISIVLIGTGLTFHNHILpadSRNV 475
Q9Y7Y9       204 TVQKAIMFLLIFSCAQQAVTSIVLDTENLRNRGn-fTWLGETLVSILFACQLVLDLALLLILSWGYTRYSTNM---RDRL 279 Schizosaccharom...
P32857       226 PLQKYLLAFFVFLTAETIFVWAYYDLKNEKGDTa-gIKVYMVFLSILTAGKVTFSFFLLLIIALGYGIVYPKL---NKTL 301 Saccharomyces c...
P38745       222 PLQRYILVFCIFLTADTIFVWMYYIIENQKGNSsvaLHVYMVFISIFSAGKMTFTLLLALLISLGYGIVYPKL---DRTL 298 Saccharomyces c...
O13989       211 QVQKYISGVVALSIVCTMVSTGYFYFANSKGYTt-gSKVFAFFLSLAQSARQSYFGFLLLIVSLGYSIVVPSL---GSLL 286 Schizosaccharom...
Q8BUV8       292 KIHWLMAALPFTKSLSLVFHAIDYHYISSQGFP---IEGWAVVYYITHLLKGALLFITIALIGTGWAFIKHIL---SDKD 365 house mouse
Q22938       246 RIQYWIGGVIVLGMVEKAFFLSEYATMNDTGSS---IDGILEVAEIVSCAKKTMSRVLVIIVCVGYGVVKPRL---GQTL 319 Caenorhabditis ...
Q9VQ34       232 RIQFWIGGVILLGMLEKAFFYAEYQTLTNKGVA---VQHAELVAEFVSCAKRTLARMLVIIMSLGFGIVKPRL---GPML 305 fruit fly
Q8BKU8       248 RIQFWIAAVIFLGMLEKAVFYSEYQNINSTGLS---TQGLLIFAELISAVKRTLARLLVIIVSLGYGIVKPRL---GTVM 321 house mouse
O04088       251 QLHSHINFVIAFTMGELAFLYLDFVYLDSAGTS---PMEVTVWAITLSSMRKALSRLLLLVISSGFGIVRPTL---GGIT 324 thale cress
XP_002596415 476 RALCLLFLPLQVLAnvAYIITESTEEGNSQYRLWREVFILVDLlcCGAilFPVVWSIRHLQEaSQTDGKA-AISLQKLKL 554
Q9Y7Y9       280 FTEAKIPLIICFFA--LFVVRFFAITIQSIHLGLWFCFFFLTAciSAL--YILFGAFVALPS-TLRALVE-QRYYTLHSI 353 Schizosaccharom...
P32857       302 MRRCQMYGALTYAIciGFLIQ--SYLTDMEAPSPLILITLIPM--ALAliIFYYMIIRSMTK-TVIYLKE-QRQIVKLNM 375 Saccharomyces c...
P38745       299 LRRCQIFAIFTFAVcvAFLVQKYSQNSESLSNL--ILITAIPL--VLClfAFYYLTLSSMNK-TMTYLRE-QNQVVKLNM 372 Saccharomyces c...
O13989       287 RKCQILAGLQFVSScfF----LSSLFISPSNKESLVILFAAPVflITLf-AMFLWIVLALNN-TIRDLRI-RKQTVKAQM 359 Schizosaccharom...
Q8BUV8       366 KKIFMIVIPLQVLAnvAYIIIESTEEGTTEYGLWKDSLFLVDLlcCGAilFPVVWSIRHLQEaSATDGKA-AINLAKLRL 444 house mouse
Q22938       320 NQVAGVGLVYFIFCsiEGIARVSKNTVEAT---RQKQFAALPL--VLTemIIFYWIFTSLAS-TIRMLRL-KRNDIKLNV 392 Caenorhabditis ...
Q9VQ34       306 HRVVGVGTLYFVLAcvESYLRITNVKTDRS----ELLVASIPL--AVLdtGICWWIFTSLVQ-TTRTLRL-RRNMVKLSL 377 fruit fly
Q8BKU8       322 HRVIGLGLLYLIFAaiEGVMRVIGGSKHL-----AVVLTDIVL--AVIdsIFVWFIFISLAQ-TMKTLRL-RKNTVKFSL 392 house mouse
O04088       325 LKMLLIGVLCFVISesLGLAMQFGNISEN-----GMNYLMLSW--AILetCFIQWIFRSLSK-TLKKLKLnKRNITKLQL 396 thale cress
XP_002596415 555 FRHFYVMIVCYIYFTRIIVYLLKITV-----------PFQYEWLGQ-FFA-ELATYVFFVMTGYKFRPASNNP 614
Q9Y7Y9       354 YKIFRIMVLCGVVTIFSFSLVALIFCsntnn-nstnkLWKIRWYFL-DGWiDGVHLTYLITLSSLWRPSQENP 424 Schizosaccharomyces po...
P32857       376 YKKLLYIIYASFLSVLAGSIVSSFIYvgmntidmiekNWRSRFFVT-DFWpTLVYFIVFVTIAFLWRPTDTSY 447 Saccharomyces cerevisi...
P38745       373 YRKLIILCYISLFILFLGLLVSTFAYvgmdtvdmieqYWKTEFLIT-DTWpSFVYFLVFVIFAFFWRPTSTSY 444 Saccharomyces cerevisi...
O13989       360 YTRLWIVICFGIVAYASIVAANAILIgiygqmnyylkYWKLLWFLNyGYT-DILVLILMLTILYLWRPTENNR 431 Schizosaccharomyces po...
Q8BUV8       445 FRHYYVLIVCYIYFTRIIAFLLKFav---------pfQWK--WLYQ--LLdETATLVFFVLTGYKFRPASDNP 504 house mouse
Q22938       393 YRHFANTLAFSVIASVIFMLWS-MIYhifp---tcrvDWKELWVDT-AFW-HVLFCFILVVIMILWRPSQNNQ 459 Caenorhabditis elegans
Q9VQ34       378 YRHFTNTLIFAVIASVIFMLFA-LRLrrve---nctpGWRDIWVDT-GFW-HILFSVLLLVIMILWRPTNNNQ 444 fruit fly
Q8BKU8       393 YRHFTNTLIFAVLASIVFMVWT-TKTfria---kcqsDWMELWVDD-AFW-SFLFSVILIVIMFLWRPSANNQ 459 house mouse
O04088       397 YKMFATVLVIMVVLSFAWIYVE-VYLyss-----lsqFWKVKWIVP-TLW-YILSYAMLVLICLFWPPSEKPM 461 thale cress
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