Conserved Protein Domain Family
COX14
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pfam14880: COX14 
Cytochrome oxidase c assembly
COX14 plays an essential role in cytochrome oxidase assembly. The COX14 product is a low-molecular weight membrane protein of mitochondria, but it is not a subunit of cytochrome oxidase. Orthology-prediction methods have identified the vertebrate C12orf62 orthologues to be orthologues of the yeast COX14.
Links
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Statistics
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PSSM-Id: 434280
Aligned: 34 rows
Threshold Bit Score: 34.574
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_001643129  2 SKYAWYTRVTDAVHRLTVLTLVGGSLYMSGGLVYTMYMNGKKYEQQQLasgssklsSDEARELE 65 
Q7PGH2        2 MKRQSRNVLLDRLHRGVVYTCMGLTMYGTYMLGVRVYRYFTVIKPARQ---------AEELKML 56  Anopheles gambiae str. PEST
EEH57064      1 MSTS--TRLMDVAFKAVTGALVGTTVVAGTWFTVTGVSAAMHYDNLARea-----aARKLAQEE 57 
XP_002507999  2 ATKSAGSRLADVVFKAVATGLFATTVVTGGWFAATAASASHHYDRLARea-----dERKARAEA 60 
EFO27343     19 HKRIFTSSVLDKLYSTTVVALIGGALCMTSVALVNVVMYYKVVKPVRE--------ADRERLEK 74 
Q6BTA7        4 SKTPLGVRITDMVHRGTVLGLVGVCVVGIGSITFNIYANSDYARMNKNkl-----aFLKEQYDQ 62  Debaryomyces hansenii
CAR25471      2 ARYPWYTKVTDAVHRLTVLTLIGGSAWMMGSLGYTMYQNGKKYEQKVTqq----leADEKRDLE 61 
Q6FM52        2 ARYAWYTRATDTLHRLTVLTIIGGSLYMTGGLVYTLYMNGKRYEQKVItd-----kKDEMNQLE 60  [Candida] glabrata
XP_453525     2 AKYAWYTRITDAAHRLTVLTLLGGTLYMGGGLVYTLYQNGKKYEEEQLll-----qEQQQQKQD 60 
CAY72108      3 KAYPWYTRATDIAHRLTIVGLVGFTFYMAGNVGWTIYQTGKQNERRLAiq-----kEMEAAKAQ 61
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