Conserved Protein Domain Family
PAP2_containing_1_like
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cd03390: PAP2_containing_1_like 
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.
Links
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Statistics
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PSSM-Id: 239484
Aligned: 57 rows
Threshold Bit Score: 152.759
Created: 28-Dec-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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active site
Feature 1:active site [active site]
Evidence:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                                                     
AAS50282   91 ITLSHPFAQvq------------rVNDAMLVVYSFVVPLAVIIvvsllfa------------------------------ 128 Ashbya gossypii AT...
EAL44542   45 VNVLYPYRDs-------------tFSEAVAGIVIYASTILIIIafqik-------------------------------- 79  Entamoeba histolyt...
EAL49461   45 PSYHYSKHEn-------------tFTRNMTITIDFFIPLICIIllclk-------------------------------- 79  Entamoeba histolyt...
EAL51301   49 PNYMFSKLNd-------------vIPRTMNVIINFYIPICVIAiisiy-------------------------------- 83  Entamoeba histolyt...
AAX69988   53 TDISHKKGKstf----------psGTLFSMEFIPIGLYLLFEAlrarlarkgewyldvketdqlidgattrvemlepeg- 121 Trypanosoma brucei
CAJ03579  190 GSLRTPFANtyh----------ehTGSRESAAVADALPSRATAsapcrqkahty-------------------------- 233 Leishmania major
CAJ07230   55 PSRADTFPD---------------YSLALMVVFSIVFYVIFIWylvrplqqffgepldwyciggadavasg--------- 110 Leishmania major
EAN78764   53 LSINNSFAEke------------tFPDWSLVVMALVSCLFIFIiekmreryspvgewymdeqlpepssnsitsstnvlse 120 Trypanosoma brucei
EAN99987   48 TSISQPPSHt-------------eTSPTYSVLIAVILVIFIYAtgeyftwre---------------------------- 86  Trypanosoma cruzi
EAO00018   72 PALIYFVVElirallwrpdtrpshGPSTSLDLVTNALETRNSErmnmrrchteeadggtvin------------------ 133 Trypanosoma cruzi

Feature 1                                                                  #      #           
AAS50282  129 -------------------------------dpshryyLLYISVLGLFLSFLSDMIITNYIKNWIGRCRPDFLERCMPre 177 Ashbya gossypii AT...
EAL44542   80 ---------------------------------rlsfkHTIFTFIGLGASVTTWLMFVQGGKIYAGRPRPNMYALVAQgk 126 Entamoeba histolyt...
EAL49461   80 ---------------------------------nhyisGLFNSILSFIFNDSLNGTITQLYKIFAGRPRPFYFNGCNPsl 126 Entamoeba histolyt...
EAL51301   84 ---------------------------------qknieKGLTVLIPFLNSEMIVGIIIQLLKRYSGKPRPFYNTYCIEhy 130 Entamoeba histolyt...
AAX69988  122 ---krseganaakagrypdespegnkendpkrlmtcleATNYWVLAHGFSIILAVCLVEILKVYAGRLRPDFLDRLKKan 198 Trypanosoma brucei
CAJ03579  234 ---------------------------alvhpwqrfllHVHIWFLTQAFSVVFALMVVSAIKVYAGRLRPDFLSRLRNeg 286 Leishmania major
CAJ07230  111 -----------egnayaepdtvantrqprvrdmqtgrgLVYPWLRAQLWSVGMDSCATAVLKVYAGRLRPDYLSRLKSag 179 Leishmania major
EAN78764  121 eraanrggasvrernglenlppapsferkvqrkfivdqVINLWILSVVFAFFFSLGIVDVLKIYAGRLRPDFLDRLRReg 200 Trypanosoma brucei
EAN99987   87 ------------------------------hgkhmvakHLNAWILVQSFSVSLDYCIVNLCKLYAGRLRPDFIHRLAKeg 136 Trypanosoma cruzi
EAO00018  134 --------------------tsdgeeaggnarwwlfleKLNHWLLAQAFSVTLSMFIVDITKLYAGRLRPDFLARLENeg 193 Trypanosoma cruzi

Feature 1                                         ###                                         
AAS50282  178 glekdvlygi-------evctttdtdrllEGFRTTPSGHSSESFAGLGYLFLWLSGqlltespa-vgawrkavAFIPLMA 249 Ashbya gossypii AT...
EAL44542  127 ---------------------------ekDAWKSFPSGHSAASFCGYTYLSLYIAGelrifsdr-pelwrmipVIIPMFL 178 Entamoeba histolyt...
EAL49461  127 ----------------------------yTCTKSFPSGHSSFSMAGLLFLSLFLYFyfkksnihlnslssvffCGLPSFL 178 Entamoeba histolyt...
EAL51301  131 ---------------------------kpTCNHSFPSGHTAYAFQGQVFLSLILLEfiskykqs-nnlivqfiVFLPCVW 182 Entamoeba histolyt...
AAX69988  199 vtegtdpk------------dlcdiakarDGRLSFPSGHSSCAFSVCTPMALYFLSvlhafsga--svwrtlvGLSPIYL 264 Trypanosoma brucei
CAJ03579  287 yspqstg--------------vdwcavpkEGRVSFPSGHSSISFSAIVPFCFYVLHslrafrrsgvslwriftGLLPLIL 352 Leishmania major
CAJ07230  180 ysssmshlpdpqtnpdyycalmdahpalkEGRLSFPSGHSSTSFAVCTVVCLFFIAhlrpfarh-asftrliiCLLPISV 258 Leishmania major
EAN78764  201 fnatspp--------------snacslarEGRLSFPSGHSSCAFAAFTPLTMYFLGlsrafnsg--pvwriilSMFPIYL 264 Trypanosoma brucei
EAN99987  137 itesnfnqf----------thdqicgaarEGRLSFPSGHASSSFAGFVPLVLYLLCrtgtlrtg--afytaaaSLLPLIF 204 Trypanosoma cruzi
EAO00018  194 ysekstg--------------vdwckvarEGRLSFPSGHAAISFSSIVTLVLFFVGhlqvfyfa--splrlflSMLPLIL 257 Trypanosoma cruzi

Feature 1            #     #   #                   
AAS50282  250 AAVIALSRTQDYRHHFVDVILGSILGMWIAWWSYRRN 286 Ashbya gossypii ATCC 10895
EAL44542  179 AGIIVLTRTRDYYHNFSDVLAGSIIGILSACIGYFSK 215 Entamoeba histolytica HM-1:IMSS
EAL49461  179 AIIIAVTRTRDHYHHFSDILGGSILGGFVAIISFFST 215 Entamoeba histolytica HM-1:IMSS
EAL51301  183 AFVVGLTRFYDHHHAISDILAGGIIGAFIAFTTYYVY 219 Entamoeba histolytica HM-1:IMSS
AAX69988  265 ACACAISRTRDNRHHFADIVAGSLIGMGTGLLAVAVF 301 Trypanosoma brucei
CAJ03579  353 PIAVAVSRTRDNRHYFDDIVAGSAIGIVSAVIAVGAT 389 Leishmania major
CAJ07230  259 SLMCAVSRTRDNKHHFSDIIAGSLIGVVSAFLSFYGS 295 Leishmania major
EAN78764  265 AICVAASRTRDNRHHFSDILGGSVIGLVIGAFSVNIF 301 Trypanosoma brucei
EAN99987  205 PLVVSISRTRDNKHHFSDIVGGAVVGTFSALFSVFLS 241 Trypanosoma cruzi
EAO00018  258 PIVVAVSRTRDNRHHFSDVLAGGIIGTGCALLSVTVL 294 Trypanosoma cruzi

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