Conserved Protein Domain Family
Msap1
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pfam17077: Msap1 
Mitotic spindle associated protein SHE1
She1 seems to be related to the spindle integrity function of the Dam1 complex. She1 is a dynein regulator and limits dynein offloading by gating the recruitment of dynactin to the astral microtubule plus end. Aurora B phosphorylates She1, modulating its potency against dynein.
Links
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Statistics
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PSSM-Id: 293682
Aligned: 2 rows
Threshold Bit Score: 373.534
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q6CNI5   1 MDkENmppllDGHQMIEYIGVSKRLGNNVLQELEQRASNLLPnvspektrLMHLGHDSEMK---------NSISMKFQDK 71  Kluyveromyces lactis ...
Q6FUD9   1 MN-EN-----DSNEIIEQLGISKRLGNSILDELNQRASETNP--------LLRKHEDTDNEeerpaestpTAHNLVFNKV 66  [Candida] glabrata CB...

Q6CNI5  72 HEKRFQVMDSIDTHYSLA---------KYSGMPQTPgkrkngsdadetsvavnlgspgsvkkkqksvgnvfsPVTDITHR 142 Kluyveromyces lactis ...
Q6FUD9  67 HNLNFENLTDKDPDFTIHndplhkkkyKYSPIKRVP------------------------------------EVNEITKK 110 [Candida] glabrata CB...

Q6CNI5 143 IRRLRVRITTPNERERTERDRRRNIISN-------TPLsrqrqlheSIPTFAQPTATSLKRKQmnNPLHKLVASDNNNVE 215 Kluyveromyces lactis ...
Q6FUD9 111 IRRLKLRSSSNLSSSGGSPEKRTTNASNveqktelAPL--------KTPNFLRPTFNSMNRAK--DTSHKVESSRRTYGN 180 [Candida] glabrata CB...

Q6CNI5 216 SQPKPKPAKPRHGDIFR-NLNQSEKQASHPRSAP----VPKQQRIPQSKS-VFERLYEQSTISRSNSSKnlLKQEkttss 289 Kluyveromyces lactis ...
Q6FUD9 181 LLPPTSRAIPAVKEAVRqDYTKRSISIQLPRKSPappkIPEQRSISDSSSnVFERLYKQTTMSRSNSMA--FDQQ----- 253 [Candida] glabrata CB...

Q6CNI5 290 dgNTSQIPRSKTqhdlhggmknarltkSTTLQNVALDR----PQWR 331 Kluyveromyces lactis NRRL Y-1140
Q6FUD9 254 --NRKQLPKSRT---------------ITGLSSVVGDKhrtfPSKH 282 [Candida] glabrata CBS 138
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