2506138 1 MTSLSSQ-PAYTLVFDPSP---SMETYSSTDfq--------------kaLEKGSDEQKIDTMKSILVTMLEGNP---MPE 59 baker's yeast 19074327 1 MGIKDAFgMDGIRKLFNDD---SFVANPLGRsqi------------vkyISSSNIKKQIQGARSLVSRMQCGED---LFE 62 Encephalitozoon cu... 19173437 1 -MQASLY-LNTSMRMRKDE---IMQKLRSS-------------------SEQ--D--KIEGMKQMIAQMSQGED---FSS 49 Encephalitozoon cu... 19114708 1 MSNLSFF-QTLSGLAENAK---QIAKSSSLSfeenels----hsdllrlLNSNSDAGKLEAINFILAQMMHGEN---MSL 69 fission yeast 19112195 1 ---MSCW-TLVQQDFLEAP---SVDALKTS-------------------LESKNDYVKISAMKTILRVVINGDS---LPS 51 fission yeast 19113227 1 ---MSS--SSSHFSSTAAD---LLAVFSSD-------------------NKDKSANKRISALKKAIAGISYGYD---MSS 50 fission yeast 19112066 1 -MVPKLF-QSSRFKAFKKS---ETSELQKG-------------------LVSQYAYERIDAVKRTIAAMTVGKD---VSS 53 fission yeast 1703169 6 HRIASAL-DTAKVITREAA---AVATSKLGEssytyysqninpqqlvtlLNSRNSREVRDAMKRIISIMASDDDsidVQL 81 baker's yeast 1168342 1 ---MSDQ-KVFARYKANEI---VTDLQHFGv-----------------kKFKSNITRRKNALRKIIANLVLGNYg-eMSV 55 baker's yeast 549719 6 KRIKKFL-KDSIRIAPKISgkgELSELRTG-------------------LVSQYPQTRKDAIKKTIQQMTLGKD---VSS 62 baker's yeast
2506138 60 LLMHIIRFVMpSKNKELKKLLYFYWEIVPKLAEdgklrHEMILVCNAIQHDLQHPNEYIRGNTLRFLTKLREAELLEQMV 139 baker's yeast 19074327 63 LCNDVIKATD-TRDVEFKRMLNLYLVRYTQGWP-----AKQLICINTMLKDFGDESSEIRHCAIQDSGLLGDGAVIKNYI 136 Encephalitozoon cu... 19173437 50 LTHKITKETLvVRSNELKRLFYYYLELLPKARGtq-sfEEMLLLSNQVRKDLEHPNEYVRGFVMRFVSTLDDQELVGNFY 128 Encephalitozoon cu... 19114708 70 YFPDVVKLVA-SENPEIRRLVHIYLLQYAEFNP-----DLALLSVNTVQKTLYDKNPLTRSTAIRVMSSIRVPAINGIVL 143 fission yeast 19112195 52 ILMHVIRFVMpSRNKELKKLLYYYWEVCPKYNNdgtmkQEMILACNSFRNDLQHPNEFIRGATLRFLCKLKEPELLDPLI 131 fission yeast 19113227 51 LFPSVISSME-SNNLELKKLCYLYLKIYASVKP-----TEAKRAVKLILNDIYSSNPMIRSLALRTLTSVNIKNFWVAAM 124 fission yeast 19112066 54 LFPDVLKNLA-TRDITLKKLVYLYLINYAKTHP-----DLCILAVNTFVKDSEEYNPTLRALAIRTMGCIRVNKIIGYLA 127 fission yeast 1703169 82 YFADVVKNIT-TNDTKVKRLIHLYLLRFAENDP-----NLTLLSINSLQKSLSDSNSELRCFALSALSDMKMSSLAPIIL 155 baker's yeast 1168342 56 LFSELLKFWQiEDDLEVKRICHEYIRVIGALKP-----QQAREALPFIMDDFKSRDEKLQIMALRTLVLVPVKELSDQAF 130 baker's yeast 549719 63 LFPDVLKNIA-TIDVEQKKLVYLYVMNYAETHP-----ELCILAVNTFITDAQDPNPLIRCMAIRTMSMIRVDKILEYIE 136 baker's yeast
2506138 140 PSVLACLEYRHA--YVRKYAILAVFSIFKVSEHLLPDA-KEIINSFIVAETDPICKRNAFIGLAELDRE---NALHYLEN 213 baker's yeast 19074327 137 NPLKEHGTSGLA--ETRRKVADSLRNYFRRDPRLFHAEgLCDLLKDLVFDEDADVCASALSSVRVLEEE----TRVLSTE 210 Encephalitozoon cu... 19173437 129 KLIKDNFNHPNT--YVRRNAYFCLGEIF-LKMDMYKEV-PDLLYHALLRDLDPNCLREAFVSLHLTDPE---LALKYAGE 201 Encephalitozoon cu... 19114708 144 LAIQQCITDTAD--RVRQSAALAITKCYSLDPSYKSQL-EEHIKTLLS-DNSPIVVPAALFTFEVVCPEkleIIHPYYHR 219 fission yeast 19112195 132 PTVRQCLEHRHA--YVRKNAILAVFSIYQVSNHLIPDA-ASLAEDFLAAESEGTCKRNALIVLFTIDPE---KAKAWLLA 205 fission yeast 19113227 125 DPIVRLLDDTDP--YVRKTAAIGIAKLYSYDKKMVESSgLIDHLKEMLSDESSVVVANSLAALMNIVNS----STGFKLT 198 fission yeast 19112066 128 DPLRKALKDEHP--YVRKAAAVCVVKMYDLDREYCASNgFIEQLQALVSDPNPVVVANAVRSLAEIHDQd--PEKGYFNV 203 fission yeast 1703169 156 HTVKKLVTDPSA--MVRGEVALAIIKLYRAGKNDYHEE-LLDILKELMADTDPKVISCAVLAYKECYADhleLLHGHFRR 232 baker's yeast 1168342 131 DCIISLVNHKSPpeQVTRTAIYALLDLDEIDHERVLGLsSILHDIVKAQSSSPEVIVAALHTLYSIHEKn-aNMEPFRIP 209 baker's yeast 549719 137 TPLRRTLHDDNA--YVRKTAVICVAKLFQLNKDLCVELgVVEDLVNALDDSNPLVIANATAALIEIHNMd-mDAVDLSSL 213 baker's yeast
2506138 214 NIADIENLDPLLQAVFvqfir-qdanrTPALKAQYIELLMELLSTTTS-DEVIFETALALTVLSANPNVLVPAVNKLIDL 291 baker's yeast 19074327 211 EIHRLLRVGIESGN--------------REVLGSLLEVMKNRAEDFPDpSPLLQLLRSCCPRIFYLASSLIISIDPSYRQ 276 Encephalitozoon cu... 19173437 202 VSLSIPS----ELS-------------TAIVEKIKDERLLERFLFSED-SMTAFEAGMSIHRMSNDEQLLKRSTDTILRC 263 Encephalitozoon cu... 19114708 220 ICTLFPQMN--DWDKV-----------VALKTLVRYARLTLPEPSTPS-THSDLKELLESIKSCFFSLLPSTIIAGARAF 285 fission yeast 19112195 206 NFEQIPSLNASSLLVIiefirkvvltkADGLEKLRFQSLLVSLTATNN-SSVVFEAATSVINVFPDAESLKLAASRLLAL 284 fission yeast 19113227 199 FSREISNKLVKSLTDC-----------SEWLQVAILDALIFYVPQKPG-EAESFAERISPWLQHGNAAVCMGAVKVILYL 266 fission yeast 19112066 204 VYTMTDRLMVALSECN------------EWGRITILNSLARFRTSDIK-EAEYVCERVVPQFQHANSGVVLSAVKVIMVH 270 fission yeast 1703169 233 YCRIIKQLD--SWSQS-----------YLIELLIKYCKQYLPKPTVVDkSSEGSPRSCPLPDKYNEIEYPSYEVVNDPDL 299 baker's yeast 1168342 210 LELAFDMLELLPELN-------------EWNKATVLEVLTTSVVPQHYlDTHEMIELALPYLQQVNTYVVLNSLKFIMYL 276 baker's yeast 549719 214 IQSHVSQFLLALNECT------------EWARIIILGTLSEYSAKDSL-EAQDIIDRVTAHLQHVNPAVVLATIKVIVRN 280 baker's yeast
2506138 292 AVKVSDNN----IKLIVLDRIQDINANNvgalEELTLDILRVLNAEDLDVRSKALDISMDLATSRNAEDVVQLLKKELQT 367 baker's yeast 19074327 277 TVFDHLQG----FFDSSDEKLYLVLDYA----ESLIEHVSYDNSCFAIYHNDKRYNKVKKLRLLFRKLDAVSMEEIKRQC 348 Encephalitozoon cu... 19173437 264 LEDLPRCR----EYAIDELLLSTYSFSG------YAMSFLSLIDPYDLSFCSKCFDFVFKISETHEFLQISDFLAFRFMD 333 Encephalitozoon cu... 19114708 286 YYLAPSNQ----MHLIVEPLLQLLLEKP-----IVRTTTLRYISQIVYKTPELFKNHIKSFFLIASDSDDTCLLKINILS 356 fission yeast 19112195 285 ADREADNN----AKLIMLDRISQLAARDksilEDLITDVIPFLSSSDFDVCEKAISIIMGLVSSRNVEDILNHFQKELTK 360 fission yeast 19113227 267 TNYMKDDNrvkeYFMKTQPPLVTLLARK----SSATQYVILRNIQIILEQCPEMFANDIHFFYCNFDDPIYVKLEKLDIL 342 fission yeast 19112066 271 IPLFSSDFtd-fLYKKMAPPLLTLLSTD-----SEIQYVALRNINLILQKRPSIFDVKTRVFFCKYNDPLYIKMEKLKII 344 fission yeast 1703169 300 DLFLQSLN----CLIYSSNPTVILSCCNa---LYQLASPLQMKNTKFIEALVRTVTMTENQGNKEMLLQAIHFLSILDQT 372 baker's yeast 1168342 277 LNYVDVIKe--tLAEKLSNSVIALLDKP----PELQFLVLRNVILLLLSRESSLLRLDISYFFIEYNDPIYIKDTKLECL 350 baker's yeast 549719 281 LPQIEYSSns-lIMKRLSSAFVSLMSTP-----PEMQYVALKNIRIILEKYPELLTKELRIFYVKFNDPLYVKLEKIDIL 354 baker's yeast
2506138 368 TVNNPDQDKAMqyrqLLIKTIRTVAVNfvEMAASVVSLLLDFIGDLNSVA--ASGIIAFIKEVIEKYPqlranilenmvq 445 baker's yeast 19074327 349 RDGELLGTILQ----ESLRADYLIEEP--FKDAQRMDEVIRVLYDADSIA---EKWNGLIREFLAGAR------------ 407 Encephalitozoon cu... 19173437 334 THDASVQNQSFr--vLLLEKMAYFASTysSYNEEMVSEALKSIASDNPEM--SHASLMFLSSCFEIMSrsse-------- 401 Encephalitozoon cu... 19114708 357 -RLLDAQNSSQ----ILPELLYYINS---HPNPSVASTAVKALGDFASAN--ISMAPSCLNTLLLLLK------------ 414 fission yeast 19112195 361 SNGETEKDDGRr--rALTKAIHSCAINfpHTAATAIQYLLSHISDFQSKS--ASSVLSFIKEVMEKFPdlrssnitklll 436 fission yeast 19113227 343 TKIADIHNLDQ----ILPEFVEYASE----IDVELVRKSVKCIGYLAIKI--EERKNDCIDSLIELMN------------ 400 fission yeast 19112066 345 TMLACDENINE----TISELRAYVSE----VELEFVKQTIKCLGDVALKV--PSVINDCISIFLEIYE------------ 402 fission yeast 1703169 373 LFLPYTKKFYVfpkdPIVASIWKIQILstLINESNVKEIFKELKYYVASA--HFPENVVIMAVKSLSRcgql-------- 442 baker's yeast 1168342 351 YLLANKETLPR----ILEELEQYATD----IDIQMSRKSVRAIGNLAVKLd-EDSVHDCVAVLLDLLE------------ 409 baker's yeast 549719 355 VRLVDPSNLKQct-lLLTELKEYAME----YEPEFVSRAIQALSQLGIKYaqESFVSKVLDILLELLE------------ 417 baker's yeast
2506138 446 tldkvrsakayrGaLWIMGEYAEGESEIQHCW--KHIRNSVGEVPILQSEikkltqnqehte--enevdatakptGPVIL 521 baker's yeast 19074327 408 ------------G-VQERQKYIYLCGRYVDKIpsEVVSIQDLNIPSLTNEti---------------------rfYLNLH 453 Encephalitozoon cu... 19173437 402 ---------sceGdAAGHGSYLEVLVNKINEV--KYGKILRCCFGILRRHa------------------------TKEIF 446 Encephalitozoon cu... 19114708 415 ----------------SHNSLIVTEA--------ASS----LRLLIHNDP--------------------------KEIY 440 fission yeast 19112195 437 slkelragkifrGvIWIAGEYCLTEDDIRVAW--KSIRASLGEVPILASEeqllkdvsnvpeddllidisapastSRKVL 514 fission yeast 19113227 401 ----------------TKVTYVIQEA-----V--IVIR---DILRKYPGS--------------------------YKSL 428 fission yeast 19112066 403 ----------------LNISYMVQEVT---VV--MET-----VLRKYPQK--------------------------IDLL 430 fission yeast 1703169 443 ---------stsWeSHVMKWLIDHMESHNLSA--SVLDAYVNVIRMLVQK-------------------------NPTKH 486 baker's yeast 1168342 410 ----------------FGVDYVVQEI-----I--SVFR---NILRKYPNN--------------------------FKAN 437 baker's yeast 549719 418 -----------------RQDTIKDDC----CI--SLC----DLLRHCPGN---------------------------DKM 443 baker's yeast
2506138 522 PDGTYATESAFDvktsqksvtdeeRDSR-PPIRRFVLsgDFYTAAILANTIIKLVLKFEnvsknktvinalkaEALLILV 600 baker's yeast 19074327 454 RRGVLCLEETLEyl--------rmLQKTsKDRVKMVAseLKARGIRVFGAFCDTKKRDLngt---------cpEEPADTE 516 Encephalitozoon cu... 19173437 447 LRVVEVLESSFG------------HADR--PLYLRNT--QTFLGAFMCIELSEMCRRLEg-------------PKDRVIA 497 Encephalitozoon cu... 19114708 441 LQYLAATYETLE--------------V---PRAKSVT-------LWLISEHILIIPRLV--------------PDVLRIA 482 fission yeast 19112195 515 PDGTYATESAVTsealsaarleavKASKkPPLRTQILsgDYYLAAVLASALTKLVMRFArlsfdkerlnalkaEACLIMT 594 fission yeast 19113227 429 VPILYENLDSLD-----------------EPDAKSAV-------IWILGQYAEEIEDSI--------------T-LLNDY 469 fission yeast 19112066 431 LPYLSRVIEELG-----------------DPRARSSM-------AWILGEFSHVIPTSS---------------KLLSEM 471 fission yeast 1703169 487 LRIIFKLADLLT------------VQTSlADN-ARAG------IVWLFGEIASIEFKIC--------------PDVLRRL 533 baker's yeast 1168342 438 VTELVKHTEVVQ-----------------EPESKNAM-------IWIITQYSDVIPNYL---------------ELFRVF 478 baker's yeast 549719 444 AKQVCAVFNTWS-----------------NPEVLLQSdiAKCNYVWLLGQHPNNFSDLE---------------SKINIF 491 baker's yeast
2506138 601 SIVRVGQSSLVEKKIDEDSLERVMTSISILLDevnpeekkeevkllevafldttkssfkrqieiakknkhkralkdsCKN 680 baker's yeast 19074327 517 CSENVSSILDIKPYYELEEGKLIANDFEKAQC---------------------------------------------EPS 551 Encephalitozoon cu... 19173437 498 VMLRFIEHGKESNTIDMSSQSTIVSCIRSLVS---------------------------------------------CNS 532 Encephalitozoon cu... 19114708 483 VKTFADETLEVKYQILELSVRLYVLSHSEEKQ----------------------------------------------ND 516 fission yeast 19112195 595 SIIRVGQSKFVKYTIDDDSVERIMNCIRAIYSfeelpefqtvflddmrkaf-------sslvaqsdkrqkeadllvnGSD 667 fission yeast 19113227 470 LKGFFDEPLEIQLTLLTAVIKVFLKKPTAAAD------------------------------------------------ 501 fission yeast 19112066 472 ISTMADEDLQIQLALLTAVVKLSLMNGKGNDE------------------------------------------------ 503 fission yeast 1703169 534 IQNFSNEGPETRCQILVLSAKLLSYDIDNFKQaqvtg------------------------------------seenNQN 577 baker's yeast 1168342 479 SSNMFSETLEVQFSILNSAIKFFIRSPTKETE------------------------------------------------ 510 baker's yeast 549719 492 IENFVQEEALTQMSLLMTIVRLHATLTGSMLQ------------------------------------------------ 523 baker's yeast
2506138 681 iePIDTPISFRQFAGVDSTnvqkdsieeDLQLAMKgdaIHATSSSsisklkkiVPLCGFSDPVYAEACITNNQFDVVLDV 760 baker's yeast 19074327 552 --AGEQPLSRGCFSSERVG---------EDVDRASp--VVEDSTAs-------SGHPQPSGLFLRREDEENVWLRFAESQ 611 Encephalitozoon cu... 19173437 533 qgEVSSDGHKRCREGVLDPimlpgtrssDERGLNKlneFLVDSEGgsaemrnvTQLTGLSDPIYVEATTSYTRYEIVVDM 612 Encephalitozoon cu... 19114708 517 leSRD-DVVSLLFNYVLSLihfd--msyDLRDRAR---FYKELAS--------TPSSEFTRRIVLES-KGNSQKEIIASR 581 fission yeast 19112195 668 avQADELLNIRQFQRVIEEkqdl-nfesDIIQATNd-gMVVEDLAskl--dhiVQLAGFTDPVYCEAYVKIQQFDIILDI 743 fission yeast 19113227 502 ---MVTNVLQWCTDEVNDP---------DLRDRGI---IYSRMLS---------ANPELAKKVILAN---MPPVNVGTGM 554 fission yeast 19112066 504 --ELVQKVLNYAINQSSNQ---------DLRDRAF---AYQRLLT--------PENVRKAQKIVCCEKPSVSYNNNLPEA 561 fission yeast 1703169 578 ppYYDFSGSRISQMYNAVLylakyddefDIRDRAR---MISSLFD--------SGKYEIVSLLLQAPKPTARSDDFIVSA 646 baker's yeast 1168342 511 --ELCMDLLKGCIDHENNP---------DLRDKTL---MYWRLLSl-------TKTSRISNAITFESLKSVLDGELPLIE 569 baker's yeast 549719 524 ------SVLELATQQTHEL---------DVRDMAM---MYWRCLS--------MPNNESLVNDLCQN--KLPMISNTLEK 575 baker's yeast
2506138 761 LLVNQTKETLKNLHVQFaTLGDLKIIDTPQKTNVIPHGFHKFTVTVKVSSADTGVIFGNIIYD-----GAHGEDARYVIL 835 baker's yeast 19074327 612 RSTGDRRASEEE------STRLIDTGGLKGILSIAGDEVVLQVDVLERPLVIYYKCKGRLNSIr----IDAEETFPLFTV 681 Encephalitozoon cu... 19173437 613 LFINQTPSYLQNILLDFvTSQGLSATFISTPFSLSSRSVVTKRFTFRIIDASNGFISGSITFRypdecGEYANTVYTINL 692 Encephalitozoon cu... 19114708 582 DYCIGTASLCLN--EDV--MGYEPIPNWADVSDLPPDSVREGIKDVLPINPHTGNIYSNNSPGv----KALSSDNFKRDF 653 fission yeast 19112195 744 LLVNRTDTTLQNLSVDLaTLGDLKVVERPPPMNLGPHAFKSVQATVKVSSTESAVIFGNIVYG-----GKASDEDKIVVL 818 fission yeast 19113227 555 YDPDTTEQLMLN----I---STLSSIYHKPPNRFVKG----AQVAYCEPSPVLRLRTRDSNPS--------NTDSRESNH 615 fission yeast 19112066 562 LLDALLCEITTL-------ASVYHKLPESFIGQGKFGADAIQRRAVEELNIEEANVHEAIEKG------ANVENLLDLDF 628 fission yeast 1703169 647 RLETHTPEIKEFFRMLP--WNTEITEVGETGNDIREGAELKDYNKYKKSFSSQSFITNNSARSf---tSSSNAKLTGIND 721 baker's yeast 1168342 570 MNTKLDPTVLEELELNIgTIVSIYLKPVSHIFRLNKT-KLLPQSPILNPNKDLLPVVGNSFPP--------TGANRDRQN 640 baker's yeast 549719 576 FSPEVLEKLLME-------LGTISSIYFKPDSNRRKGKKYVQNIVKGKHIEELESMAKNEISS-----KANDDVLLDFDE 643 baker's yeast
2506138 836 NDV-HVDIMDYIKPATADDEHFRTMWNAFEWENKISVKS-QLPTLHAYLRELVKGTNMGILTPSESLGeddcrFLSCNLY 913 baker's yeast 19074327 682 NLPvINSKFRLTIGKSVYEIHLGIRSLMRPCECQKDEFEkRFKELRDYILLK--EFNMEKTYVVDSYS-----FSFSVLG 754 Encephalitozoon cu... 19173437 693 SEV-KTSVSEFLEPRKMDPDGFRETWKELEWENTYTLKFiTKKTLEEIFGEVSRALNGETLDIECDEDya-vgNIACSTL 770 Encephalitozoon cu... 19114708 654 GDTnAINRPKFVGQQTLEEFYASETSESSEGEYETSTSEsEDEETDDTSQE---EDNEKNSTPDEDTEn----NNTSSIS 726 fission yeast 19112195 819 NGI-PVNIIDYIKPAFIPESQFRSMWTEFEWENKVDISSnEDISLYDFLHKIMKKTNMNCLTPDASLRgd-cgFLSANLY 896 fission yeast 19113227 616 KKY--NHFHQKSQTRRVMEQYDRNSWNPSPFSDESNSNT-FSGKFDSADQE---NLGMPMTPETHLMD------------ 677 fission yeast 19112066 629 TDP--GATSASDSPITSAQPQSGSNSAMDLFMAFEAPSTnNAEPVKARSAT---DDLLGL-------------------- 683 fission yeast 1703169 722 GDSnSISGKGNVNTFTSQNGKKYRLQSLDEFFSDIPERKsKPRKIIKVVEESSDEDEDESEESSDDDE-----YSDSSLG 796 baker's yeast 1168342 641 SES---QSSTKSRKTAMMDDYDKPAEKINQLKGKRKSSSnNPSKLSRKPSTLLRKLSMKRPFS----------------- 700 baker's yeast 549719 644 RDDvTNTNAGMLNTLTTLGDLD-DLFDFGPSEDATQINTnDTKAVQGLKELKLGGDSNGISSGGKNNPd----VSGGNIV 718 baker's yeast
2506138 914 AKssfgEDALANLCIEKdskTNDVIGYV 941 baker's yeast 19074327 755 SRf--yGKHLDGQVILKg--PKRLLGLF 778 Encephalitozoon cuniculi 19173437 771 QN----VCVLVNVCLRR---SEHVHFES 791 Encephalitozoon cuniculi 19114708 727 TK----S--IMDRPLTE---PEPNYWQS 745 fission yeast 19112195 897 ACsifgEDALMSLSVEKs-vSGPISGHV 923 fission yeast 19113227 ---------------------------- fission yeast 19112066 ---------------------------- fission yeast 1703169 797 TS----SSGTSSSHLEL----------- 809 baker's yeast 1168342 ---------------------------- baker's yeast 549719 719 SQd------LLDLF-------------- 726 baker's yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",