3ADB_B 13 LIILTGLPGVGKSTFSKNLAKILSK--NNIDVIVLG-SDLIR------ESFP--VW-KEKYEEFIKKSTYRLIDSALKN- 79 Methanocaldococcus ... Q86H29 3 LIVLSGPPCSGKTTRAKELYEHFTN--LGKKVIIIN-EESLLi-----NKNEg-YK-DSLTEKMTRGSLKGATDRNLSKd 72 Dictyostelium disco... O46079 3 LVVITGLPASGKSTRARQLRDHFVE--RGRKVHLISeNEAVPka--gfGKNS--HTgDSQKEKVVRSDLKSEASRHLNQe 76 fruit fly Q7Q9K5 3 LIVITGLPRSGKTSRAKELEKYFTEl-GKGPVHIVS-EADCIarsgcgVKES--FT-DTGKEKQIRASLKSEAMKLLTKs 77 Anopheles gambiae s... Q5I0L7 3 LVVVCGLPSSGKSRRTEELRRALTG--EGRSVYVVD-DASVLg-----AQDStvYG-DSAGEKALRAALRAAVERRLSRq 73 Norway rat Q6FME7 3 LVLMCGFPLSGKSTVARELAGYLRE--KGANVVVHS-DETLGhkgretREED--YN-DTHAERKLRNEIMSAVRRDLSRs 76 [Candida] glabrata Q96EK9 3 LVVFCGLPYSGKSRRAEELRVALAA--EGRAVYVVD-DAAVLg-----AEDPavYG-DSAREKALRGALRASVERRLSRh 73 human Q6LX62 2 LIILTGLPSVGKSTFSKAFSKKMAE--KNIDNIILG-TDLIR------ESFP--VW-KESYEEFIRDSNNYLIKEALENk 69 Methanococcus marip... Q9LMH0 3 LVVICGQPCSGKSIAAVTLAETLKEseTKQSVRIID-EASFHl-----DRNQn-YA-NMPAEKNLRGKLRSDVDRSVSTg 74 thale cress CAP38298 3 LIIVTGHPASGKSTIVDRLAQKFSE--SQKECQIIR-DDAYGs----fSRKN--YE-FANKEKDLRSWIRSEVQQNLTKn 72
3ADB_B 80 YWVIVDDTNYYNSXRRDLINIAKKYNKNYAIIYLKAS-----------------LDVLIRRN-----IERGEK------- 130 Methanocaldococcus ... Q86H29 73 TVVISDSLNYIKGYRYELYCIARAAGTRLLVLYCNTP-----------------RDLAKKWN-----QERDQSv------ 124 Dictyostelium disco... O46079 77 DLVILDAGNYIKGYRYELYCMSKVSRTTQCTVFTCIP-----------------QEEAWTFN-----SQRTAPdelpgds 134 fruit fly Q7Q9K5 78 TLVIMDGTNYIKGYRYEIFCMSKNARTTQCTVHCAMT-----------------VEQRNARR-----EEIVQSsss---- 131 Anopheles gambiae s... Q5I0L7 74 DVVILDSMNYIKGFRYELYCLARAVRTPLCLVYCIRPgwpsrglpvpgacessdPAVSVSWRpradyGEKTQAvgaveqr 153 Norway rat Q6FME7 77 TIVIVDSLNYIKGFRYQLHCECKNSNTGFMLVHCMAT-----------------YADILKRD-----ENGEESp------ 128 [Candida] glabrata Q96EK9 74 DVVILDSLNYIKGFRYELYCLARAARTPLCLVYCVRPggpiagpqvaganenpgRNVSVSWRpraeeDGRAQAagssvlr 153 human Q6LX62 70 FSVIVDDTNYYNSKRRDLMNIAKECDTNYVTIYLKAP-----------------LNLLLKRN-----IERGQK------- 120 Methanococcus marip... Q9LMH0 75 EIVIVDSLNSIKGYRYELWCIARAAGIRYCVVYCDVD-----------------EAHCRQWN-----KERSDRge----- 127 thale cress CAP38298 73 KVVICDGLNYIKGYRYELFLAAKMSKTTYCVIQVTPS-----------------SDTCHWLN-----EQKPEGe------ 124
3ADB_B 131 --------------------------------------------------IPNEVIKKXYEKFDEPGKKYKWDEPFLIID 160 Methanocaldococcus ... Q86H29 125 -------------------------------------------------aYSEKLLDELTNRFEVPNPKNRWDSPLFTLE 155 Dictyostelium disco... O46079 135 erv--------------------------------------qpvdnsdvpYTRETFDALCQRYEEPQSNNRWDSPLVVVL 176 fruit fly Q7Q9K5 132 ------------------------------------------------geLDAETFDALCQRYEEPQDTSRWDRPLFTVY 163 Anopheles gambiae s... Q5I0L7 154 aisplanggvptavpkeldp----kdilpsnppavmtpeseksaepapcaFPPELLESLALRFEAPDSRNRWDRPLFTVV 229 Norway rat Q6FME7 129 -------------------------------------------------rWGKELLDQLIQRFEEPDASNRWDSPMATVV 159 [Candida] glabrata Q96EK9 154 elhtadsvvngsaqadvpkelereesgaaespalvtpdseksakhgsgafYSPELLEALTLRFEAPDSRNRWDRPLFTLV 233 human Q6LX62 121 --------------------------------------------------IPNEVIKNMYEKFDTPGTKYAWDLPDITVD 150 Methanococcus marip... Q9LMH0 128 ------------------------------------------------dgYDDGIFEDLVRRFEKPERRNRWDSPLFELY 159 thale cress CAP38298 125 -------------------------------------------------rYSREIIDQLLMRYEKPDTKFRWEQPLFEVK 155
3ADB_B 161 ------TTKDIDF----------------------NEIAKKL-------------IEKSKEIPKFYVLEENKnKNNNISD 199 Methanocaldococcus ... Q86H29 156 ------PQHTLPH----------------------ELLFKTL-------------FEVQELRPNYATQSQSL-SPANFVH 193 Dictyostelium disco... O46079 177 ------PKDTLDM----------------------EAIYKAL-------------YESQPLPPNQSTYNAPL-GTTNYLF 214 fruit fly Q7Q9K5 164 ------GGEEMEL----------------------ARIHSAL-------------YEQAPLPPNLATQNMPL-SATNFLF 201 Anopheles gambiae s... Q5I0L7 230 g-----LEEPLPL----------------------AEIRSAL-------------FENRAPPPHQSTQSQPL-ASGSFLH 268 Norway rat Q6FME7 160 spetllPTHKQLV----------------------DQVLLGIsdksssrngspspGPMNRLSQNNPTLLKAA-TGADFVR 216 [Candida] glabrata Q96EK9 234 g-----LEEPLPL----------------------AGIRSAL-------------FENRAPPPHQSTQSQPL-ASGSFLH 272 human Q6LX62 151 ------TTEKIDY----------------------NEILNEIle----------iNENKNLKIEEDKIPKSE-PVESDLV 191 Methanococcus marip... Q9LMH0 160 psr-evIDKSSPV------------------------ILEAVtyltkt--vdsktQDVRILQPSIATQAARF-SEANSLY 211 thale cress CAP38298 156 ig---kAEKALPTeidddmsidleypaprfanifdDEIVEWI-------------CNGTQLTENQSTQTVPL-APTNFLH 218
3ADB_B 200 KIDKETRKIVSEYIK----SKKLDKDK-----------------------------IKEVVELRKEFLKKIKk------X 240 Methanocaldococcus ... Q86H29 194 ELETKTQEITSVISDalqsSMVGDYIKvpgtekrv--------------vihsklnLVELRNQRRQFYKFAQ-------L 252 Dictyostelium disco... O46079 215 ELDKIVQAIIKEILGav-kIKAFGQLRipgsrnpv--------------kvatsmnALQLNRLRQKFITSTCha---sqT 276 fruit fly Q7Q9K5 202 ELDKSTQTIIDQIAAar-kIGLDGPVEipqagmra--------------evpanmsVAQLNRHRRQFLNYVKmh----tN 262 Anopheles gambiae s... Q5I0L7 269 QLDQATSQVLTAVMEaqksAVPGDLLTlpgttehl--------------rftrpltLAELSRLRRQFISYTKm-----hP 329 Norway rat Q6FME7 217 LLDAKLTETVRIIVRecqaAQAIGGPQriivsedvrdinddrclfldipadapqltLPRLNRLKRQFVQMNKn------L 290 [Candida] glabrata Q96EK9 273 QLDQVTSQVLAGLMEaqksAVPGDLLTlpgttehl--------------rftrpltMAELSRLRRQFISYTKm-----hP 333 human Q6LX62 192 KIDSLTRNIVGNLIK----TGKIDKKD-----------------------------IKLLSEIRKSFLKDCKki----eS 234 Methanococcus marip... Q9LMH0 212 ELDRATQEIINAIVEqqslGAAISRVTlgnelppi--------------eicrpigLPELRRLRRTFVKLMGqsslsgpP 277 thale cress CAP38298 219 ELDRCTQDVVTVLLNaqrtAVRGQNLTipgasegsn-----------qvkflklrtLPELNRLRHQFVNMSKk------D 281
3ADB_B 241 EEVDADRVLKEFKDLLN 257 Methanocaldococcus jannaschii DSM 2661 Q86H29 253 HPPQPHLIADSFVDFLN 269 Dictyostelium discoideum O46079 277 SPTPLEQVPHLFVQFIN 293 fruit fly Q7Q9K5 263 VSSDISKIPAIFVQFLN 279 Anopheles gambiae str. PEST Q5I0L7 330 NNENLPQLANMFLQYLN 346 Norway rat Q6FME7 291 RDVDLERAAPLFVAYIG 307 [Candida] glabrata Q96EK9 334 NNENLPQLANMFLQYLS 350 human Q6LX62 235 EKLDFEKIEKDFLDYLN 251 Methanococcus maripaludis S2 Q9LMH0 278 LPTDADSAKRRFVDYLN 294 thale cress CAP38298 282 PMSDKEKIINGFVDFLN 298
Jiyao W et al.(2023). "The conserved domain database in 2023.",