Conserved Protein Domain Family
COG5028

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COG5028: COG5028 
Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
Statistics
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PSSM-Id: 227361
Aligned: 7 rows
Threshold Bit Score: 861.02
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
731688     1 MSQqn-iLAASVSa--------lSLDESTVHTGGASSKKSRRPHRAYHNFSSgt--------vPTLGNSP---------- 53   baker's yeast
19074042     --------------------------------------------------------------------------------      Encephalitozoon cu...
19074065     --------------------------------------------------------------------------------      Encephalitozoon cu...
19115643   1 MSQedafYGKGSYgassgnsnipPQGFQPVYPVAGQLDNTAPYVGAVAEGTAegivsngeyavGAMGAAPtniigsvdqq 80   fission yeast
19112268   1 MAYp---gQFGNYg--------nPETYRQNVAGNIASYGGPEIDTQLAAQMN-----------AQMYIQQg--------- 49   fission yeast
731857     1 MSH----HKKRVY----------PQAQLQYGQNATPLQQPAQFMPPQDPAAAgm-------syGQMGMPPqgavpsmgqq 59   baker's yeast
1730731    1 MSH----HKKRVY----------PQAQVPY----------------------------------IASMP----------- 21   baker's yeast
731688    54 YTTPQLNQQDGFQQPQAFTPKQFGGFNNG------SGSVMSt--------PVMVSQERFgaseaSSPYGQS--MLDMTAP 117  baker's yeast
19074042     --------------------------------------------------------------------------------      Encephalitozoon cu...
19074065   1 ----------MHSRDFASQAMHQAGKQFP---------------------KAFESQRK---------------------P 28   Encephalitozoon cu...
19115643  81 PPVSHTSHKSRRQYPAEVFELTNTLAASPappslsEPSYVMartp--sssPYPHDRAEVgtkslSAQFGGMslGADGAAA 158  fission yeast
19112268  50 SAMAPQPRRARRHKDAHAYDMSLTDAEPAl-----AP-VMS---------PAIPPSMNYptpstPSVLPESfsNDTNLLD 114  fission yeast
731857    60 QFLTPAQEQLHQQIDQATTSMNDMHLHNVpl--vdPNAYMQpqvpvqmgtPLQQQQQPM-----AAPAYGQpsAAMGQNM 132  baker's yeast
1730731   22 --IVAEQQQSQQQIDQTAYAMGNLQLNNR------ANSFTQ----------LAQNQQ--------FPGSG---------K 66   baker's yeast
731688   118 QPTSHIVPTQRFEDQAQYLQRSFETCRDSVPPLpTTQFYCVDQGSCDPHLMSLSMYNIPESEHLRAATKLPLGLTIQPFS 197  baker's yeast
19074042   1 -------------------MEHRGSGFEADCQD-EEGSVSNSIVDES-SYYRSTVLAIPEKQDIIRMCGIP--LVINVVL 57   Encephalitozoon cu...
19074065  29 KMKIPDFPSELEKDQE---SFFSFDTSIQPPPLsTTNCFITETTNTDPNLLRSTMYTLPTDTDTFESMEIPFGLVLNPFN 105  Encephalitozoon cu...
19115643 159 MPTNELVSVDLYNQTP-EISDLTSPPPPINLPL-SYSATGAATSNCPPKYVRSTINCVPTTNSLLKKSKIPFALVIRPYT 236  fission yeast
19112268 115 PAALPSAPEVRYEDQQLFKNQIFNTMEKGSPPMsTTDFVGYEQGNSSSKFVQFTSYAIPATNDVCNASGIPLGMIVQPFA 194  fission yeast
731857   133 RPMNQLYPIDLLTELPPPITDLTLPPPPLVIPP-ERMLVPSELSNASPDYIRSTLNAVPKNSSLLKKSKLPFGLVIRPYQ 211  baker's yeast
1730731   67 -VVNQLYPVDLFTELPPPIRDLSLPPLPITISQ-DNIVTPSEYSNVPYQYVRSTLKAVPKTNSLLKKTKLPFAIVIRPYL 144  baker's yeast
731688   198 TLTPndaEVPTIPLPMDGT--PLRCRRCRAYANPKFQFTYDS-SVICNICRVKMQVPGEHFA-------PMGPNGQRSD- 266  baker's yeast
19074042  58 ENYE---EEGIPLCSED----IVRCECCKSYLNPFVEIIPPGlKWRCNVCLAINDLATAFQVtsrtaahDSGAFDPRANa 130  Encephalitozoon cu...
19074065 106 QKAM------ATELDKNIS---VRCWQCQSYVN-IFTRIEGS-VFYCNICNSKNQAREGISNe-----iTRYSTIEYVDr 169  Encephalitozoon cu...
19115643 237 SLVE---EDDPVPVVTDTI--ISRCRRCRMYINPFSIFIDNGhRYRCNSCGIVNEVPQSYDW-------DSFRNVQRD-- 302  fission yeast
19112268 195 ELRP---DEAPVPVVDNTNsnPPRCKKCRGYINPFIQFTMASsKWTCNLCGSENSFNDDGFN-------PLVGSQHDG-- 262  fission yeast
731857   212 HLYD---DIDPPPLNEDGL--IVRCRRCRSYMNPFVTFIEQGrRWRCNFCRLANDVPMQMD--------QSDPNDPKS-- 276  baker's yeast
1730731  145 HLQD---SDNQVPLNTDGV--IVRCRRCRSYMNPFVVFINQGrKWQCNICRFKNDVPFGFD--------QNLQGAPIN-- 209  baker's yeast
731688   267 -----LNEKSELLHGTVDFLVPSIYNAIQEKellPLHYVFLIDVSLLANENGSSLAMVEGVRSCIEYISDFQPNCEVAII 341  baker's yeast
19074042 131 aynscYYSRTELRSTVYELEAPPNYSLKTPS---PPFICFLIEVTFESMKCRAVDAVIRSILGGLDPK-SFDPRSRMMFA 206  Encephalitozoon cu...
19074065 170 -----TRGGKEEKSELGNVVSEGLFRTTVVH---GPAFVFGIDITVPTLMDRAFKAIGRLIKDENFQF----LFKKIGMV 237  Encephalitozoon cu...
19115643 303 -----RWQRPELNYAVVDFIAPQEYMVRAPQ---PLVYVFLIDISFVSISSGMVGTASRAILESLDRIPNKEGRAKVAFI 374  fission yeast
19112268 263 -----VESRPELNVGTIDFKVGKDYWIKEDPp-kPARFVFMIDVSYEASSKGLPKVAAEAIRNILYGPVPLDPNVKIAIV 336  fission yeast
731857   277 -----RYDRNEIKCAVMEYMAPKEYTLRQPP---PATYCFLIDVSQSSIKSGLLATTINTLLQNLDSIPNHDERTRISIL 348  baker's yeast
1730731  210 -----RYERNEIKNSVVDYLAPVEYSVREPP---PSVYVFLLDVSQNAVKNGLLATSARTILENIEFLPNHDGRTRIAII 281  baker's yeast
731688   342 VYDNKLRFFNLRPDL--------DNa---------------------QEYIVSELDDVFLPFYNGLFVKPGNSMKIINDT 392  baker's yeast
19074042 207 FFDSSIYLLKKNGDF---------------------------------SIISDATYIPFFLED--DFLLPLDHHLD---- 247  Encephalitozoon cu...
19074065 238 LFSDTVSLIKPSSGV---------------------------------ITEVLLPDRFQLPFISPEFLMDVEDEKLMK-L 283  Encephalitozoon cu...
19115643 375 GVDSALHFFSVSPGAe-------Ea----------------------TQLVVSDLEEPFLPRN-QDLLLNLRECRQGIEN 424  fission yeast
19112268 337 CFDRSVNFFNLSPNLe------qP-----------------------HMLAASDLENPFVPFSSGLFVDPIASKVVIER- 386  fission yeast
731857   349 CVDNAIHYFKIPLDSe------nNEesa----------------dqiNMMDIADLEEPFLPRP-NSMVVSLKACRQNIET 405  baker's yeast
1730731  282 CVDHSLHYFYVPLDDdyevsdedDEesdgeeededeeeedvdnsetiQMFDIGDLDEPFLPMPSDELVVPLKYCKNNLET 361  baker's yeast
731688   393 LIKISGYISTDkySHVPQVCYGSALQAAKLaldtVTGGQGGKIICSLNSLPTIGNGNLSLKRD-------NAHIaHVKCD 465  baker's yeast
19074042 248 -VARVERFFIE--NKSTKNNYGDALRVVQS----ILGATGGCIISFLATHPNMGSGSVD-----------PSQR-ELRCK 308  Encephalitozoon cu...
19074065 284 LVDYVSRIPVG--KGKPKSGVGDCLKIAVS----IAGYCKGSKVAVF-T-------NVQ-----------------DILE 332  Encephalitozoon cu...
19115643 425 LLERFQSMFAT--TRDSSNALGPGLKAAHR----LIENIGGKICCLISSLPNVGVGKLELREDpkllgtnRESS-LLHPN 497  fission yeast
19112268 387 LLDSFPAIFQD--VKIPEPVVGNALEVVKL----LLKETGGKAFVFVSALPTMGLGKLRHREDqrlygtsDEKN-LWNTQ 459  fission yeast
731857   406 LLTKIPQIFQS--NLITNFALGPALKSAYH----LIGGVGGKIIVVSGTLPNLGIGKLQRRNEsgvvntsKETAqLLSCQ 479  baker's yeast
1730731  362 LLKKIPEIFQD--THSSKFALGPALKAASN----LIKSTGGKVEVISSTLPNTGIGKLKKRSEqgilntpKESSqLLSCK 435  baker's yeast
731688   466 NGFYKKLASDFLKSYISLDLYVTNAGFIDMATVGHPVEMTSGILKYYPHFQQET--DAFTLVNDMVTNVSNIVGYQALLK 543  baker's yeast
19074042 309 SVFYKEMSAHLSKQGISVTQFLFPRLGIELPTLSVLNKYTGGMLYYYPNFDGSDpaFTTKLANDLASHLDLNTGLHGMCR 388  Encephalitozoon cu...
19074065 333 H---EEISKQLIEVGCSLNVFST-----QKTSAARLCASTAGRSFVYTPESLTR------LESDLVSLGITKSSYKVRVE 398  Encephalitozoon cu...
19115643 498 DSFYKSFAVECSTSQVSVDMFLFSSQYQDVATLSCLPRYTSGKTQFYHRWNASRseDALKFASELTNYLSMEIELEAVMR 577  fission yeast
19112268 460 DKWYTSLADEYVTAGIGVDIFFTATAYVDVATVGSVATLSGGQIYHYSNFVADR--DGSRLKQDLFRSVTREQGYRVMLK 537  fission yeast
731857   480 DSFYKNFTIDCSKVQITVDLFLASEDYMDVASLSNLSRFTAGQTHFYPGFSGKNpnDIVKFSTEFAKHISMDFCMETVMR 559  baker's yeast
1730731  436 DSFYKTFTIECNKLQITVDMFLASEDYMDVATLSHLGRFSGGQTHFYPGFNATSlnDVTKFTRELSRHLSMDISMEAVMR 515  baker's yeast
731688   544 VRCSTGLSVEQYYCDSSDNTDHDPIIPVLTRDTTLDVLLKYDSKIKTgTDVHFQTALLYTDIDGVRKVRSINTSGAVSNN 623  baker's yeast
19074042 389 VRASRCVFIKEYFGSLHHRSADLLSFSTFFPPHSLNFEIDISKEEGT-KGVCFQVAILRTLRTGERRIRVVNFCIDRVS- 466  Encephalitozoon cu...
19074065 399 AKTSDAVRKLGFYGNTVFEHLGFQDFAQMDDKTTLGMTFSLEEPLQNkSKVYIQVILNFYCFDGSSRTLVMNSSFEASSR 478  Encephalitozoon cu...
19115643 578 VRGSNGLRMSSFYGNFFNRSSDLCAFPSFPRDQSYVVEVVIEDTITK-PFVSFQTAMLHTTCNGERRIRVLTISLPTTNS 656  fission yeast
19112268 538 TRCSNGLRVSKYLGNFLQRTPQDIEFGSLDADKSVTVLFSYDGKLNGaLDAHFQTAVLYTTPSGERRVRVVNYCCAVTSK 617  fission yeast
731857   560 ARGSTGLRMSRFYGHFFNRSSDLCAFSTMPRDQSYLFEVNVDESIMA-DYCYVQVAVLLSLNNSQRRIRIITLAMPTTES 638  baker's yeast
1730731  516 VRCSTGLRATSFFGHFFNRSSDLCAFSTMPRDQSYLFGISIEDSLMA-EYCYLQVSTLLTLNTGERRIRVMTLALPTSES 594  baker's yeast
731688   624 IREIFKFINQNPVMRIMIKDVIKTLGDCDFVKIRRLIDDKMVEILTQYRG-LVSSNSSTQLILP--DSIKTLPAYMLAFE 700  baker's yeast
19074042 467 -RSLYSVVDPYAIAHALALKAFFFES-RSKGGGNEYLNKSMKDIIRAYK---QLSNTTTLLP----ATLEVLPMLVLSLC 537  Encephalitozoon cu...
19074065 479 ISEVYASLSFDTLACIYAKYIAMDES--VVKEHCKKVESTISRSLKYYRNsCCKEASSSQFVLP--ESIKLIPLIYQAML 554  Encephalitozoon cu...
19115643 657 MTDLYASADQVAIAQYLTVRASEKALSSTLNEARDSIISKLVEILEVYKKnLAGQNTGAAIPLQisTNLRLLPLLCLALT 736  fission yeast
19112268 618 SYDTISLAIVEPIVAVLAKIASTNIAAGSLKDTSVRLVEGVVKILSSYRKvAANRLTPGQLVLP--KNLVLLPILILAVL 695  fission yeast
731857   639 LAEVYASADQLAIASFYNSKAVEKALNSSLDDARVLINKSVQDILATYKKeIVVSNTAGGAPLRlcANLRMFPLLMHSLT 718  baker's yeast
1730731  595 AREVFASADQLAITDFMTQNAVTKALNSSMYSARDFITKSLEDILNAYKKeISMSNINSVTSLNlcANLRMLPLLMNGLS 674  baker's yeast
731688   701 KSELMKpnAQSTRGNERIYDLLKYDSLNSAQLCYKLYPQIVPFHVLLEETDLTfyd--anDKLLQINSSSINnls-vrAS 777  baker's yeast
19074042 538 KSIPLRp-VSYTPMDYKSYYIYLITNSYPKLVDTVIYPTLLALH-------------------RLDTIQPLN------LT 591  Encephalitozoon cu...
19074065 555 KNSCFS-----N--DINIECVSRITGFTVEQNLRFFYPRLFAFTDFYIDK--S-----------LEKVKALK------LT 608  Encephalitozoon cu...
19115643 737 KHTGFRr-SSHISSDLRSIALCYLSTLPTPLLMRYIYPTLYSLHDMPIEAGTV-------TEQGVVLPSALN------LT 802  fission yeast
19112268 696 KSSAIR--SGSIHSDIRVSQLREVRAAPIQELMLNLYPNIYALHQLQPTDCLP-------DP-ENTGCLPINmplcvrAS 765  fission yeast
731857   719 KHMAFR--SGIVPSDHRASALNNLESLPLKYLIKNIYPDVYSLHDMADEAGLPvqtedgeATGTIVLPQPIN------AT 790  baker's yeast
1730731  675 KHIALR--PGVVPSDYRASALNRLETEPLHYLIKSIYPTVYSLHDMPDEVGLPd------FEGKTVLPEPIN------AT 740  baker's yeast
731688   778 HSNFINGGCYLIFQGDTIYLWFNENTNRMLLQDLLSVDEslpVSQISLFSGTLPETGT-SINQKASNVIKNWQQVVNKSS 856  baker's yeast
19074042 592 LDCLETNGLYLLDTGVTIFFFVARNCDPSLPDLLFDP-------SIGSERFIFDPERN-EFSDSVCKIIEELRS-NRYLT 662  Encephalitozoon cu...
19074065 609 GESLNSEEIYVLDNSQKIYIYIGKDVDASLKEAIFTD------------KT--------EENEILHRMIDEFYS-YYDSE 667  Encephalitozoon cu...
19115643 803 SALLQSFGLYLVDTHIHQFLYIGKDAVPQLLIDAFGVNS---LADLKAGRFTMPVIDN-PLNVRINAILGKLRSLDKGST 878  fission yeast
19112268 766 RKFIEDGGAFLIVTGQKSYLWFHQRTSPLLLQDLLGVES---LEDIDSLKALELPTLDtVLSVQVRNLLSSLRMQFPSMA 842  fission yeast
731857   791 SSLFERYGLYLIDNGNELFLWMGGDAVPALVFDVFGTQD---IFDIPIGKQEIPVVENsEFNQRVRNIINQLRNHDDVIT 867  baker's yeast
1730731  741 ISLFERYGLYLIDNSAELFLWVGGDAVPELLIDVFNTDT---ISQIPVGKSELPLLNDsPFNERLRRIIGRIRENNDTIT 817  baker's yeast
731688   857 LP--LVLLRPN--VDQY----------YSNVMSQLLCEDKTVNrIESYDNYLVIMHKKIQE 903  baker's yeast
19074042 663 PN--YVLVRDN--GASSv---------YKDIFFTYFVEDESHG-LPSYSRYLDLLRA---- 705  Encephalitozoon cuniculi
19074065 668 LP--VVFVEEG--KGGS-----------EVEFIGYLVEDRLNN-IPSYPDYICELHFKVKS 712  Encephalitozoon cuniculi
19115643 879 IMpsLYLVRGD--GDPQ----------LRSWFFSHFVEDRSEN-SPSYLQFLQTLKEKVRD 926  fission yeast
19112268 843 LH--PQIVRQG--LDGS-----------EGEIFSTLVEDNTRE-GFGYLDFLTKIHESLHT 887  fission yeast
731857   868 YQs-LYIVRGAslSEPVnhasarevatLRLWASSTLVEDKILN-NESYREFLQIMKARISK 926  baker's yeast
1730731  818 FQs-LYIIRGPsiNEPAnlnsekdmasLRLWVLSTLVEDKVLN-CASYREYLQSMKTSINR 876  baker's yeast
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