6SN5


Conserved Protein Domain Family
Omp85
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pfam01103: Omp85 
Omp85 superfamily domain
The Omp85 protein superfamily contains bacterial outer membrane proteins, which can function as protein translocases or as membrane protein assembly factors. The family includes the membrane bound beta barrel of proteins such as BamA and TamA from E. coli.
Links
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Statistics
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PSSM-Id: 460065
Aligned: 44 rows
Threshold Bit Score: 130.169
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6SN5_A 425 NWLGTGYAVGINGTKN-------------D-YQTYAELSVTNP---YFTVD---------------GVSLGGRLFYNdfq 472  Escherichia coli
Q8F3T2 560 NLNGTGQKISGRLEf--------------GpFRRLFQITWTEP---WLYNK---------------PWSLSLSLFYSsri 607  Leptospira interrogans
O83346 462 NFLGKGNEISVNATLG-------------S-EAQSLKLGYVER---WFLGS---------------PLTVGFDFELThkn 509  Treponema pallidum s...
O51735 460 NFLGEGYYFAARLNl--------------SfLEQSLSLTFRDN---WFFQK---------------RWTVGGFIDFShsv 507  Lyme disease spirochete
Q2YPP8 334 NLFGRGERLRFDAKVSgiggsqdnsfdpkN-YTYLLGASFAKP---GVYTP---------------DTDFVATLDAK--- 391  Brucella abortus 2308
Q92LN9 318 NLFGRAESLRIEGSVDrlget----tdvaG-LDYSAGILFAKP---GAFGP---------------ASTFTASVKAA--- 371  Sinorhizobium meliloti
Q9A7W6 329 NRQKRADtttya-------------lrfaK-LEQRLGAEISLP---HWRRP---------------QQTLKLNSSVF--- 373  Caulobacter vibrioides
Q9RXD5 506 NAFGLGHSFGVRLGavq----------nqAgQNWVGSLNYTIPwldLDFAD---------------FRKNRTSLSFGvgs 560  Deinococcus radiodurans
Q8KC70 551 NLYGTGNSAGVWAKIG-------------Q-KNNRFNLEFSMPrigSTPLTmftraffdqrdfetrQLALIGQSGLQa-- 614  Chlorobaculum tepidum
Q8KBW3 349 NLFGAGQQLKLSTNYG------------------------------RQLSS---------------DTNVLSSLSA---- 379  Chlorobaculum tepidum

6SN5_A 473 ----------------------------addADLS-DYTNKSYGTDVTLGFP----IN-------EYNSLR-----AGLG 507  Escherichia coli
Q8F3T2 608 ynvgavs---------------itennnqqsIKEQaIYSRDGVGFTVGIGHRifinWThfhryspSIYAST-----NPSS 667  Leptospira interrogans
O83346 510 lfvyragsygng-----lphpytsreqwassPGLAeSFRLKYSRFESAIGAHtgyqWY-------PRYAVIrvnggVDFR 577  Treponema pallidum s...
O51735 508 ntayqdingpifsgkrevpdpftsweeyrdaKSFSdFNAMNYSLLKLSFGAFtgytFSnylgkqtLLGTLQ-----TALK 582  Lyme disease spirochete
Q2YPP8 392 -------------------------------REVLdAYTETSINAKTGFTQI----FS-------DELSGA-----LYAN 424  Brucella abortus 2308
Q92LN9 372 -------------------------------IVDPdAYSAKTVTAAAGAAFE----LS-------PEDTFS-----VGAE 404  Sinorhizobium meliloti
Q9A7W6 374 -------------------------------RNDTdAYNETGATVGVDLTRR----RQ-------TTAYRT-----FGVS 406  Caulobacter vibrioides
Q9RXD5 561 dvggn------------------ialldankEDTGrDYTTRTNGFSLGLGRNitpnLT-------ASANVA-----FNNR 610  Deinococcus radiodurans
Q8KC70 615 -------------------------------TGEPrSLGIQRYGITTSFGTR----IG-------KNGRLT-----ADFT 647  Chlorobaculum tepidum
Q8KBW3 380 --------------------------------DQYdKLIPYEFNIKADLVIPrlgkQG-------SYYNGT-----VEYA 415  Chlorobaculum tepidum

6SN5_A 508 YVHNSLSNMQPQVAMWRYLysmge---------------------------------------------hpstsDQDNSF 542  Escherichia coli
Q8F3T2 668 LVSDQVLAEVRRG------------------------------------------------------------------- 680  Leptospira interrogans
O83346 578 VVKNFYDKDNNQPFDLTV---------------------------------------------------------KEQLN 600  Treponema pallidum s...
O51735 583 YVFYDNEVNRPSNYYLR----------------------------------------------------------DNYKT 604  Lyme disease spirochete
Q2YPP8 425 ASQGHFVDDVFGK------------------------------------------------------------------R 438  Brucella abortus 2308
Q92LN9 405 VGWAD-VDDAFGS------------------------------------------------------------------N 417  Sinorhizobium meliloti
Q9A7W6 407 FDLSQ-TKEQVNRNGLI----------------------------------------------------------AGRKL 427  Caulobacter vibrioides
Q9RXD5 611 TSYLEPKQEGETSNLDDAAa------------------------------------------------------TALLPA 636  Deinococcus radiodurans
Q8KC70 648 VQNAQSYIRDNIDEPF-------------------------------------------------------------ATG 666  Chlorobaculum tepidum
Q8KBW3 416 QSKLPVLLDSKRELIRATYstrptrvskldfdffelevarkdslrgfqqlfkndlaqniginpadpvavnrgldSLLQTR 495  Chlorobaculum tepidum

6SN5_A 543 KTDDFTFNYGWTYNKLDRGY-FPTDGSRVNLTGKVT---------------------I---PGSDNE--YYKVTLDT-AT 594  Escherichia coli
Q8F3T2 681 WQFRSQISNGIAYDIRDNVF-NPTQGYDLLFQIDNV---------------------Gq-aLGGQSH--FDQYRVLA-EY 734  Leptospira interrogans
O83346 601 WTSINSFWTSVSFDGRDFAY-DPSSGWFLGQRCTFN---------------------GlvpFLEKEH--SFRSDTKA-EF 655  Treponema pallidum s...
O51735 605 FRFENSLSLSAAWDTRNSTS-LSNNGFLLKQQFDFF---------------------Gg-fLFGQSH--FIKSSTTF-ER 658  Lyme disease spirochete
Q2YPP8 439 DFTTAGLEGNLLYDSRNNKP-DPSSGFYLVGNIQPF---------------------Ye-fHYGNF---ATRFTAEG-RT 491  Brucella abortus 2308
Q92LN9 418 SYITAALPFEYVRDARDDKL-NPTEGYRALINAKPS---------------------Ye-iEGKTF---FSSFEASA-SG 470  Sinorhizobium meliloti
Q9A7W6 428 NLATLAGLAAYAWDFSDDIL-DPKRGWRLETRAEPT---------------------Yv-aGDTSVP--YLKLAGQG-SA 481  Caulobacter vibrioides
Q9RXD5 637 TSLTTRLSGNLNYDNTDNVN-FPGRGVRAYGALGYN---------------------Vg-rAGDAPL--SWTDGEIGvSG 691  Deinococcus radiodurans
Q8KC70 667 NVNLASIGGQFTFDNRDSSF-LPSGGRYTNIRYTST---------------------Sa-lLNNADS--FWQFSALHe-- 719  Chlorobaculum tepidum
Q8KBW3 496 LNQTFRLRYSLSNREKSTRSkRSPIWNFSVTAEESGsllwlidkyidkksyagftdsDp-qIFGTPYnqYVKLDTQL--- 571  Chlorobaculum tepidum

6SN5_A 595 YVPIDDd--hKWVV-------LGRTRWGYGD-GLG--------------GKE-MPFYENFYAGG----------SSTVRG 639  Escherichia coli
Q8F3T2 735 YHTWFDy--sFFGLfrnnalrRWRVVQEFRSsSLFtyqrvpyygkqdpiQKPyIQLQDLQFLGG----------YESLRG 802  Leptospira interrogans
O83346 656 YVTLL----------------------NY---PVS--------------AVWnLKFVLAFYTGVsvqtyygrrkSENGKG 696  Treponema pallidum s...
O51735 659 YFSLLGyedvFTPYfdiiltlRSVYSNILPPlGNGf-------------EIEiQPHHHIILSEN----------FMQARG 715  Lyme disease spirochete
Q2YPP8 492 YHGFGQt--dRVVL-------AGRLKVGSIV-GGS--------------IAD-LPPSQLFLAGG----------GGSVRG 536  Brucella abortus 2308
Q92LN9 471 YYAFGTe--kRFVL-------AGKLGAGVLVgGDE--------------LSD-IPATRRFFLGG----------GGSVRG 516  Sinorhizobium meliloti
Q9A7W6 482 YLPFGKq--dSTVL-------AARVKLGAIL-GAG--------------LLD-VPASRRFFSGG----------GGSVRG 526  Caulobacter vibrioides
Q9RXD5 692 YYGFGGrikrSFGLetyrqvlAARANTGT--------------------TTGtFPDGTGYFIGG----------SNPLAS 741  Deinococcus radiodurans
Q8KC70 720 ---------eNFSI-------SSATTLQLTAlAGT--------------SSEeVPLSEKFFLGG----------TGNAYS 759  Chlorobaculum tepidum
Q8KBW3 572 --AVTKnlspKRQV-------AARIALGWMS-PYG--------------KADtTPEDHRFYAGG----------SNSMRG 617  Chlorobaculum tepidum

6SN5_A 640 FQSNTIGPKAVyfphqasnydpdydyecatqdgakdlckSDDAVGGNAMAVASLEFITPTPFISdkYansVRTSFFWDMG 719  Escherichia coli
Q8F3T2 803 WFYNDAKYPA------------------------------EWRDGAATRMMFGSELRFPIEPTL------LWLVAFFDAG 846  Leptospira interrogans
O83346 697 NGVRSGALVIDgvlvg------------------rgwseDAKKNTGDLLLHHWIEFRWPLAHGi------VSFDFFFDAA 752  Treponema pallidum s...
O51735 716 WGILKNIY---------------------------------------SSFVNTVQISIPLLKNi-----lVWDAFFIDFA 751  Lyme disease spirochete
Q2YPP8 537 YGYRNIGVSAG----------------------------NGNIIGGRSLVEANGEVRTRItd-------sIGAVAFVDAG 581  Brucella abortus 2308
Q92LN9 517 YSYQEISPRDA----------------------------DDELTGGRSYVSGSLEARIAVtd-------tIGVVPFIDAG 561  Sinorhizobium meliloti
Q9A7W6 527 YAYQAIGPRLS----------------------------DNTPQGGISLVETSFEVRQKItd-------rWSGVAFVDAG 571  Caulobacter vibrioides
Q9RXD5 742 RELRGLEDG---------------------------------QLFGTNYFSSSLEYRYDFGLSGgvAq-gLYGVLFADYG 787  Deinococcus radiodurans
Q8KC70 760 YRFIGLKDS---------------------------------DLIGNNIAVAGAMLRYKVPMQL--Lf-pTSLTLSYNIG 803  Chlorobaculum tepidum
Q8KBW3 618 WVFGTLGPGSCpn-------------------------aAVSNFGADIKAELGLEYRIQFFKVF--Gq-eSGIALFTDAG 669  Chlorobaculum tepidum

6SN5_A 720 TVWDTNWDSSQYSGypdys------------dpsniRMSAGIALQWMSP-LGPLVFSYAQ-PF----KKYDG-DK----- 775  Escherichia coli
Q8F3T2 847 ALYEEVNRATGVRKdlfetydq-------rvreaqmKDPVGYYLANNYNlTALRKADYTFeEL----NNPANlVLsgnn- 914  Leptospira interrogans
O83346 753 MVYNIESQSPNGSSsasssssssssssrttsseglyKMSYGPGLRFTLP-QFPLKLAFAN-TF----TSPGGiPK----- 821  Treponema pallidum s...
O51735 752 S-YSLEGQENSLFRpfs-----------------sfAFSWGTGIRSLLP-QLPLSFVIAY-PFyfdnDKVNSyYK----- 806  Lyme disease spirochete
Q2YPP8 582 YV--GEKSFPDFSEq--------------------mRVGVGGGLRYLTS-LGPIRLDVAV-PL----NRRSG-DP----- 627  Brucella abortus 2308
Q92LN9 562 TV--SDSTAPDFSDi---------------------rAGAGIGLRYATP-FGPIRLDFAV-PL----NKYPG-GT----- 606  Sinorhizobium meliloti
Q9A7W6 572 AI--GTHETPQREDf---------------------rAGAGLGVRYDLG-FGPIRADIAA-PL----GRRKG-DP----- 616  Caulobacter vibrioides
Q9RXD5 788 GVWNSGEAFRSAYGv---------------------GAGVQLNLGFGGAqLPSLRFDYGY-SG----QNAQK-------- 833  Deinococcus radiodurans
Q8KC70 804 NVWEKRKQMSISKL----------------------IQGVGAGLVWDTP-IGPAQFTVAK-PF----AFERDdVNdsar- 854  Chlorobaculum tepidum
Q8KBW3 670 NIWDRTGPYAFSLRslt----------------qdfAWDWGAGLRIGSP-IGPFRFDFAW-KL----HDPANpQPwrfsq 727  Chlorobaculum tepidum

6SN5_A 776 ---AE-QFQFNI 783  Escherichia coli
Q8F3T2 915 valDKfRFSWGV 926  Leptospira interrogans
O83346 822 ---TKkNWNFVL 830  Treponema pallidum subsp. pallidum str. Nichols
O51735 807 ---YYsGFKFFL 815  Lyme disease spirochete
Q2YPP8 628 ---NY-GFYVGI 635  Brucella abortus 2308
Q92LN9 607 ---DY-GIYAGI 614  Sinorhizobium meliloti
Q9A7W6 617 ---KF-QIYLSI 624  Caulobacter vibrioides
Q9RXD5 834 ---PNgRFHFRI 842  Deinococcus radiodurans
Q8KC70 855 idfTDtVFYFSL 866  Chlorobaculum tepidum
Q8KBW3 728 tklTDfTFNFGI 739  Chlorobaculum tepidum
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