Conserved Protein Domain Family
Gpr1_Fun34_YaaH

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pfam01184: Gpr1_Fun34_YaaH 
GPR1/FUN34/yaaH family
The Ady2 protein in is required for acetate in Saccharomyces cerevisiae, and is probably an acetate transporter. A homolog in Yarrowia lipolytica (GPR1) has a role in acetic acid sensitivity.
Statistics
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PSSM-Id: 426106
Aligned: 155 rows
Threshold Bit Score: 142.616
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EKD12627  58 FGGEFQPGl--------YKPTTERKFANPAPLGLSAFALTTFVLSLINIGVRGVSQSNIVISLAFGYGGLVQLLAGMWEM 129
KIS65995  70 lsRTLTPGghyadddllAIANSHRKIGNPLPLGVFGFSTTTLLLSLYNVQVQGINIPNAVLGFALTYGGLAQFLAGLWEF 149
EKD02960  33 msrfitpgghpadnsqpALPVFHRKFANPAPLGLMGFGGTTLLLSLYNLGARGVEKPNVLVGVALMYGGVCQIICGCMEW 112
EKD03955  33 isrfitpggnpmdtsqpAFPVFHRKFANPAPLGLLAFGGTTFVLSLYNAQARHITVPNVILGLALGYGGLAQIIAGIEEW 112
Q5KF52    41 mtrfitpgghpmdtsqpAFPVFHRKFGNPAPLGLISFAATTFLLSLFNISTRGITVHNVILGMALGYGGLCQIIVGIEEW 120 Cryptococcus neofor...
Q5KD83    75 pidtsQPG----------FPVFHRKFGTPAPVGLIPFVGGAFLLNLYTVQARGVTKPNMILGIALGFGGLGQIIAGILEW 144 Cryptococcus neofor...
Q5KAD0    66 GGNPVDTSq-------pALPNYHRALGDPAPVGLIPLSSGTLLISLYNVQTRGITTPNIILGLALGFSGIVQTIAGILEW 138 Cryptococcus neofor...
EST07377  46 evdssQPG----------FPIYHRRIANPFPLVTIATGAYLLMLGLILVGHRGIRNPAILMALGLPLGMVGNFAACMFSF 115
EGN92059  14 dsyyvqaaspdtppaqpMMQPYQRTYGNPAPLGMLAYGTVFLCSSILTLHAGNVTTPNLVLVFATFYGGISQTLVGMWEM 93 
EKD03979  36 iervitpgghpidfsqpAIPVQHRKFGNPLPAALISFSTGFFFLGLLNIGTRGIVTPHVIFPVLIMFLGITQTLTGWFEM 115
EKD12627 130 AVGNTFGATALSSYGGFWLSLAILLTPgGFDIAAAYsptdstgaatGAGVNDFNNAFGYFLAGWFIFTFILLLCTLRSTV 209
KIS65995 150 ASGNTFGATVFCSFGMFWWGYAVLLIP-FFGFMGTYngqpgiyaqgSPYAAEADNAIGLFLWIWFGITTIYLIASTRGSV 228
EKD02960 113 ACGNTFGTCAFTGYGAFWVSFACINIP-WFGVAKAY----------EKNPNEMAQAVGLYLVMWGIVTCFLLTALLRSSV 181
EKD03955 113 ACGNTFGSTAFTSYGSFWISFGVLYIP-QFEVLTAY----------AGKGHMLDDALAIYLTMWAIITFIFLLGTFRSSV 181
Q5KF52   121 ACGNTFGATAFCSYGGFWLSFAALYIP-QFEVLASY-----------DDPAMLDNALGLYLVAWALVTFILLLACLRSSV 188 Cryptococcus neofor...
Q5KD83   145 ACGNTFGAVTFSSYGAFWLSLSTLYIP-QFGVAAAY----------AENPAMLENALGLYLCVWGIVTVLFLIASHRSSV 213 Cryptococcus neofor...
Q5KAD0   139 ASGNTFAAVALTSYGGFWFSFAVLYIP-QFEVTASY----------ASDISMLANGIGLYLVMWGILTFLFLLASLRSSV 207 Cryptococcus neofor...
EST07377 116 AEGSTFLATTAGTLAGLIGGSSLLFLP-WTGIQATYilgg---tsqAAGLEEYYKAAAMVYFISLIPIFLIFLASMRTSG 191
EGN92059  94 FLGNTFSATVFTTYGGFNFSYGALYLP-QMGLAAAYtv-------dGVVGEEFSHAIGIYLGIWALITFVFCLGAIRTTA 165
EKD03979 116 FIGNTYSATIFVCYGGFIFSYSLIYLP-SMGILEAYtdket-----glprpEFHSAVGIYLGIWAGITFLFIIASLRSSV 189
EKD12627 210 AFFMLFFTLTLAFLMLAVGHL--EASDAgvpqsaCIKAGGYFGIFAAFLAWYNAL------AGIADDSNSF--FVIPVAH 279
KIS65995 229 SLFVLIFLLWVTFIFLGAHAY--TGNAH------LQTAGGAFGIATGFAGFYLGT------ASFLSPYNSF--FTLPVIP 292
EKD02960 182 ALCFTFFVVACAFFCLAAGDL--CASHA------AKLAGGGFGIAGGLGAMYVAL------AGLLDGNTSY--FTLPIgn 245
EKD03955 182 ALFLVFFFLEITFWLLAAGHY--TGHKT------VTKAGGGMGVVTAFTAFYTAL------AGLLTRETSW--ILIPTgd 245
Q5KF52   189 ALICVFVFLDITFWLLAAGYL--APSTN------ATKAGGAFGILTAAVAAYTGL------AGMLTKDTSY--FILPVGD 252 Cryptococcus neofor...
Q5KD83   214 VLICIFGALSLNFFILSAGYL--SESPK------CIKTGGAIGIITAIFGAYTSL------AELVTADTGF--FRVPIgn 277 Cryptococcus neofor...
Q5KAD0   208 ALISLFLMLDLSFWLTAAGYL--SQNEK------ILKAGGGFGIAAAFCGFYVAL------ASLLSGHTSF--FLVPTgd 271 Cryptococcus neofor...
EST07377 192 PTSGAALMIVIALGCLGGGYIkgEANQT------ILKAAGAFFIATGVSLFYAATsvmlaeEGLK---------ILPVFP 256
EGN92059 166 PIVVTLFFTVCALSCLSASSF--TGNAH------LNTAGGALGIVASFGAYYGAL------SLFWTQQTTFsyIRLPPli 231
EKD03979 190 AILSTLVFTCISFALLAAAEI--GGSPS------VKTASGATCMIAGLCGYWSAM------AGYWTPDITY--VQIPPID 253
EKD12627 280 FPW 282
KIS65995 293 LSK 295
EKD02960 246 lap 248
EKD03955 246 lsp 248
Q5KF52   253 LSh 255 Cryptococcus neoformans
Q5KD83   278 ltp 280 Cryptococcus neoformans
Q5KAD0   272 lrp 274 Cryptococcus neoformans
EST07377 257 LPR 259
EGN92059 232 lap 234
EKD03979 254 LSR 256
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