Conserved Protein Domain Family
NBP1

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pfam08537: NBP1 
Fungal Nap binding protein NBP1
NBP1 is a nuclear protein which has been shown in Saccharomyces cerevisiae to be essential for the G2/M transition of the cell cycle.
Statistics
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PSSM-Id: 400720
Aligned: 12 rows
Threshold Bit Score: 266.582
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CCH61144         1 MFDSVQKLVTDLFnsgdnyerKHRRDPRKVD-------YGNLNDIKARSRYFPKSSHRPssnnisntrnnti-------- 65 
XP_002496485     1 MLESVRGFIGDILg-------YQATDPRKKE-------YGSLDDVRTSNRQGGSGSHARld------------------- 47 
Q6CPH9           1 M-ENLKQYWNSWW---------YENDGRKSDkyplktrY----------------------------------------- 29  Kluyveromyces...
Q758V0           1 MLEPLKNIVSDFW---------LKTDTRKRE-------YGSLDEWKQQRGQERIGRPRR--------------------- 43  Eremothecium ...
ybcl:Ecym_2805   1 MFQPLKDMMMDMW----------SGDSRKKE-------YGSLEEWKQIKQNDRIGRPR---------------------- 41 
EDO18369         1 MLDSLKGFVDDFFgkg--nqdYDEDDGRKRD-------YGELSELRDRRKRRRAVAAKErnrmlrmkrgdpgvadeiysr 71 
XP_003687256     1 MLESVQGMARGFFgqd--sedRTPVDGRKHE-------YGDLEYMKAQRRKRMADRSSSarahlmrevngn--------- 62 
CCE93899         1 MLESMKRYLGDVL----------GNDPRKRE-------YGDLEDVRRERQERSPIRDRSra------------------- 44 
P52919           1 MLKSVQGLWKDFFg--------IRDDGRKRE-------YGSLDEVRKRSALRSRRKQM---------------------- 43  Saccharomyces...
Q6FSI5           1 MFETIKDLFAGVV---------TTSDRRKKE-------HGSLADIKRRSMNKRK-------------------------- 38  [Candida] gla...
XP_003954878     1 MMKSIQAFVNDFFh------nAENEDERGRQarrssvvHNDMGMRIRKKSNKIRNAHKL--------------------- 53 
XP_003677678     1 MLQSVQHFFTEFFnrs--pknIDNCGRRKKY-------YNGLKGMRRKERGRSLKRRSDsvlhr---------------- 55 
CCH61144        66 ------pnridrvkfedfQNDSRS--KSIKRSSNKNSKNYVTDKHRNLLTHNHDKIPtlkrkqlktrklhnyfLKKSSLY 137
XP_002496485    48 ----------------rnRLRRRR--AIASNGDSANSRKYVRPQDGNRVNKMRNPSAr---------------TGPGTLS 94 
Q6CPH9          30 ------------------RGTKTS--DRYYKVQKPNTTRASRLRREPEVSEYRKPNP----------------AENGSQP 73  Kluyveromyces...
Q758V0          44 ------------------RASTRY--KVTKPSAVHQSALPLPVERPGAAAVRRNER------------------------ 79  Eremothecium ...
ybcl:Ecym_2805  42 ------------------RATGRY--KVTKHSAVHKSVLPIQQNRRDGVFLKQQRQRqeqeeq-----rdqqqQQNDESP 96 
EDO18369        72 srgsrvqhrsleggvhkpRNSDSA--SASSAANNYNGGTRRRQYREVSPEFVTGVPP----------------RNNGRLR 133
XP_003687256    63 ------esgevllntvrnRNRGGV--KKSVNGERRKGRMYQEKVEREMLAGRIARNQ----------------RNPGTLT 118
CCE93899        45 ----------------rvGPRSKN--RPTANFAGNGSRRMLRKERMARSNGIVKKKPpv-------------rDNSGGLK 93 
P52919          44 ------------------RPTGKSvlKRPRKVTDRKTEEKIRTNRRK--------------------------TPKRRLT 79  Saccharomyces...
Q6FSI5          39 ------------------RALGHN--KSITNTDQRNAEYLNKLKMRNSIRGKVGKPPlrggymn--svdikpdTKESRAR 96  [Candida] gla...
XP_003954878    54 ------------------RPKEHG--NRIGKISGASRNVALSKRYTN--------------------------KSQRSFS 87 
XP_003677678    56 --------------elypSLSSEN--KHFKTVSDPKPSRQLKT-RRNRIEKTYNNYPkv------------ktVKDSLLR 106
CCH61144       138 SIWEFILQIFSNDAHDLKSIRNTSKPLI-----------ESPDISTSNDKLIRDRIGRSQAFRNKIQEFKkkdrtSSKQQ 206
XP_002496485    95 KLMKSIKNVFSTEDQDLTLMQQACGNTNamlp---paarRGAHQGAEGRKKLRDRIVRSEAFKRKLLEIK-----YDDRM 166
Q6CPH9          74 STWSKIKSLFDSNRRDITELKQAYLDY------------RLPNTEPSNTQADIDRLVVNERFKKKLLERK-----YERNM 136 Kluyveromyces...
Q758V0          80 TWWDRLCGVFSAEQRDLHGMRDAFANYRlp--------pTEELEGRRRRGTASQRIARSETFKKRVLEKM-----YDDRM 146 Eremothecium ...
ybcl:Ecym_2805  97 TWWERLTSVFSSEQRDLYDMKNAFTNYRlp--------fTNEHESRRRRATNSQRIARSETLKKRMMEKI-----YDDKM 163
EDO18369       134 TLVNSIKSVFSNDTQELNMMQRASENLNvlv------pvSPALSEREERMLIQDRIIRSEVFRKKLMEKR-----HDDVL 202
XP_003687256   119 KILSAIKTIFSPEAENMGRMKRVSESLDqllpesnrisdSARCSQMEERRRMRERIGRSEAFKRKLLEKR-----NDEAL 193
CCE93899        94 SIWRSLKTVFSSEDQDLDLMQRACSNVTsmi------psKNKISGPEERRQLKERIARSEAFKRKVLQVK-----YDDKM 162
P52919          80 KIFQTIRDVFSNDNENMSKMQNVCGDMTril-----kkrSQGRPSYMDTDTAKSRILRSDAFKRKISELK-----YNKQR 149 Saccharomyces...
Q6FSI5          97 MVLNAVKSIFSNEDQTL--MNMASTDINkllr---------nqgyDKNQENLKDSILRSNAFKKKVTELE-----YNKRM 160 [Candida] gla...
XP_003954878    88 TFFKFIKSMFSNDEQNLRRLKNECSNIYvn-------spNLESKTNEEYRKIKNRIESSDAFKRKLNELK-----YDRTQ 155
XP_003677678   107 SLLSRLGTLFSNNEYSMERMQKTCNNISai-------vqPNPLKSGEEQEILVRRITASKAFQKKLKDIQ-----YDKQM 174
CCH61144       207 PKRLRKRLPINIDSARllrnppiskkthn--------ttipynednltlNNKYFDEVNQLKRKIKKLASELENKDSELEK 278
XP_002496485   167 LEQVRRGRSVSGSRRRigeg-------------------------yqgiEPLQDDKVGLLQRKLQELDSKVQDMDKELQI 221
Q6CPH9         137 LNELRRGRQPYRRNREhrps--------------------------vnsPINHADEVILLRKKLDELEQRLSDAVEELVI 190 Kluyveromyces...
Q758V0         147 LEQLRAGSRGRRPERPa-------------------------------lPGSDADQVVLLQNRLHKLERQLFETQKELEL 195 Eremothecium ...
ybcl:Ecym_2805 164 LQQLRETGNPNKRAERllg---------------------------lnlSNSESDQVVLLQNRLRKLEQQLFDTQKELEI 216
EDO18369       203 LEQLKRGRSKTVDTPGyvs---------------------------ssnLNITNDQVTLLQKKIDDMEEKITSLTKELQI 255
XP_003687256   194 LDQLKRGRPSYRQNDDidrenetidaefssdakndisrrdynrkvksrnLNIVDDQVFLLQKKVDSLESKLNIVEKELYL 273
CCE93899       163 LQELRRGRSRQRSEDPv-------------------------------gSNLTDDQVTLLQKKITHLETRLKNALEDLQI 211
P52919         150 ISELRSGSSDGSSGKDr-------------------------------nQSLYLDREILLQRQIKKRDEKIKALESKLQS 198 Saccharomyces...
Q6FSI5         161 LRDLRRSGVSGNYNIIr-------------------------------dDDLEEDRYLLLQKKYQKIKKRLYEVEQELKS 209 [Candida] gla...
XP_003954878   156 IEKIRKTTRLNKHARSpr------------------------------kNGVLDDRLKLLNKEVQDLKRRLHDKSVELE- 204
XP_003677678   175 LTQLKSRVPDKNISYRsql----------------------------ssNNITEDKIRLLSIKNRELETELNKTKDLLQL 226
CCH61144       279 IRIQLKFANEKNQLREDLLDDAKLDNGYLISRRQIKNLEKQN--VKPK-EELIYSPVR--IPNPKYTSSPMNKPGTYDSN 353
XP_002496485   222 TQKKLKFAQEKNTLLESLLDDANIDSEYVKSRRDIKNLQKEN--LKPE-AELPPSPRR--SVNPLFTSSPMRKPPSVQDQ 296
Q6CPH9         191 TKKKLEFVQQKNNLLEELFDDGKMETEYVKSRRNITNLQNSE--RKPElKQLPRSPSPvlHVDPMFTSSPIRATNNILGE 268 Kluyveromyces...
Q758V0         196 AKKKLMFAHEKTKLFESLLDDANVDDDYVKSRRRITNLRATTd-NQPAlRSLSPSPQRpyPVNPLFTSSPIRQVN-DSPR 273 Eremothecium ...
ybcl:Ecym_2805 217 ANKKLTFAQEKTKLFESLLDEANVDNEYVKSRRRISNLRTTA---EPQlRSLSPSPKRpyPLNPLFTSSPMRAHNADSPG 293
EDO18369       256 SKKKLKFAKEKNLLLQSLLDDANIDSEYVKSRRDIKNLQKEN--LIPE-TDLPPSPKR--TVNPLFTSSPMRKPTIEANE 330
XP_003687256   274 SKKKLKFAKEKNSLLESLLDDANIDSEYVKSRRDIKNLQKEN--LIPE-ADLPPSPRR--TVNPLFTSSPMRKVSGSTKK 348
CCE93899       212 TQKRLKFAKEKNTLLESLLDDANIDREYVKSRRDIKNIQRDN--LKPD-TELPPSPRR--TVNPLFTSSPMRNIATREEP 286
P52919         199 LQEALNYSNEKYRILEDLLDSSNIHPSYTKSRRTMSNLARENdeIKPLkIDLSPSPIR--RTNSLFTSSPMKT------- 269 Saccharomyces...
Q6FSI5         210 VQDSLRYSQEMNALLQETLDKANIDDAYLKSRRQIKNLQKEN--VLPE-RELSPSPRR--PIDPLFTSSPVRKSRNGEEN 284 [Candida] gla...
XP_003954878   205 -------------LVDARLDTALKDNKWLRSRIADMELTEEKgsNISQ-HKMPHISTS--FKDSLQYSSPTK-------- 260
XP_003677678   227 TKKDLKFAKDKNDLLQSLLRDEKTDEKFLQYKAHVLNSSTGN-------------PGR---NDGYLASSPSSQENRDNDF 290
CCH61144       354 PFNyi------gePKTPYLYDKY-RKLPETEQLNKlqiqeti---psndndSGEDISLSPVAVDISKYS 412
XP_002496485   297 EQEqvqg---qgqDPTQNFYSKY-PKIPETELLVQ----------------GRDRTSMSPIRIDYSKYS 345
Q6CPH9         269 GSPqh-------vQQHDNFYEKY-PRIPKTERLDNyrsslan--heddyqdRHAENSLSPVRVDYSKYS 327 Kluyveromyces lactis
Q758V0         274 KQI----------NKPDDFYAKY-PTIPKTELLNKqpse--------naaaGRAKESLSPVRIDYSKYS 323 Eremothecium gossypii
ybcl:Ecym_2805 294 KHP----------NDIHDFYAKY-PSLPKTEVLNNkgsa--------pdqiSNSSESLSPVRIDYNKYS 343
EDO18369       331 DDDmnt-----gdIGPDEFYSKY-PKIPETETLTQ----------------HGKEKSLSPIRIDYSKYS 377
XP_003687256   349 NEEev------gkPTTSEFYNKY-PKIPETEKLKQ----------------DIRERSLSPINIDYSKYS 394
CCE93899       287 ASS------------TTDFYNKY-PKIPETETLAN----------------NQRSDSLSPIRIDYSKYS 326
P52919         270 -------------------YNRD-GNIPEMQPLQEnispacptppyrsretEKEDETLSPISVDFSSYL 318 Saccharomyces cerevisiae...
Q6FSI5         285 GSKpktdykhspiKETSNFYDKY-PKLPETEQLAQ----------------DKGNHSLSPIRIDYSRYS 336 [Candida] glabrata
XP_003954878   261 -------------------FKRYdSNILESDEIKDilkqygd---dkdynsDDDTGSLSPIRIDYSKYS 307
XP_003677678   291 GTP--------------NYYNRY-PKIPSTEVLKKnhg-----------rhDHHNNSLSPIRIDFTKYS 333
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