Conserved Protein Domain Family
Peptidase_M76

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pfam09768: Peptidase_M76 
Peptidase M76 family
This is a family of metalloproteases. Proteins in this family are also annotated as Ku70-binding proteins.
Statistics
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PSSM-Id: 430811
Aligned: 118 rows
Threshold Bit Score: 141.142
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001568808  36 DVCEAAVDYVLRNV-NTIQYMIQSIEEITGkPFLRDR-IKCLPlaprngapcvstrgltpdrvyagyiwrsgrsdC---Q 110
XP_002903803   4 yECEDAVQVALQQRrPQHIFLAQQHREGKS-AVPAID-FVCLD--------------------------------Crddg 49 
EEB15206      51 KVCEKNVLSAINDN-PLIKLLMGALKKAGC-PVNLRRhIVCEE--------------------------------CstlV 96 
XP_015791003  68 EMCEYQVLSVIKNY-PLIKLLERAMKAHGC-ELDYRRhFSCEP--------------------------------CvgkM 113
EFX67841      50 TTCERNVYNCFENS-PLVKLMYSALKASGC-EIDLRRhIACEV--------------------------------CdvsV 95 
EEC20274      70 fwCERNVQKCFENS-PLVKLMLSALKSAGC-EVNIRRnVCCEP--------------------------------CdkaV 115
1_pfamImport   1 -RCEKTVYKCFKTG-KLVQLMAGALKASGC-EIDLRRhIVCEV--------------------------------CdpkV 45 
XP_001846255  70 iKCERNVYKCVKNS-PMVKLMMGALKSSGC-AIDIRRhIACEV--------------------------------CdvsV 115
EFA00208      60 iKCERNVYKCIKQS-PIIKLMMGALKSSGC-PVDIRRhISCEE--------------------------------CdpsV 105
XP_008202847  54 iKCERNVYWCLRNS-PLVKIMLGALKSSGC-EFDFRRhISCEV--------------------------------CdskV 99 
XP_001568808 111 -AK---D--------VVLLEDHVarlfstkhaatflkkekgdnectllspstsrtaaaaasspsttasppqlerllvesq 178
XP_002903803  50 pEGnarAffsappptVVFCANRL--------------------------------------------------------- 72 
EEB15206      97 -TG---Gydqe-fnqIVLCQNTM--------------------------------------------------------- 114
XP_015791003 114 -TG---Gydif-fnqIVVCSNKY--------------------------------------------------------- 131
EFX67841      96 -SG---Gydpk-lnqIVVCQNVV--------------------------------------------------------- 113
EEC20274     116 -TG---Gydpe-lnqVVVCQNSA--------------------------------------------------------- 133
1_pfamImport  46 -SG---Gydpe-lnqIVVCQNSS--------------------------------------------------------- 63 
XP_001846255 116 -SG---Gydpv-lnqVVVCQNIA--------------------------------------------------------- 133
EFA00208     106 -SG---Gfdpv-lnqVVVCQNGA--------------------------------------------------------- 123
XP_008202847 100 -SG---Gydpv-lnqVVICQNVA--------------------------------------------------------- 117
XP_001568808 179 lPVLEQVERSIRHELVHAFDDARGAIEYSDCMHQACSEIRAARLSgDCFVGQEMRKg---rFNFFEG-----GQKCVRRR 250
XP_002903803  73 -HSVREVEETMVHELIHAYDFTVRKMDITKSDILACSEIRSARES-ECYQKAKLLEtvlpdVEFFKKsarwlNSRCVREH 150
EEB15206     115 -KGRRMPEVTLVHELIHMYDHCTKEMDLKNLEHLACTEIRAANIA-HCSFLSSFFLggsslFSIKDT-----HQYCVKKK 187
XP_015791003 132 -MSKGQFMGTIGHEMIHMYDACRAKLDFTNPEHVACTEIRAANLM-HCSIPGSIYKgttplYRWSDT-----QKECVREK 204
EFX67841     114 -RNKGIIQGILTHEMIHMFDACRHQLDFKNIHHLACTEIRAANLT-HCSFMSAMFQgdaspIRIRKQ-----HAECVKMK 186
EEC20274     134 -RRRGMVQGILAHELLHMFDQCRAKMDLKNIDHLACTEIRAANLF-HCSFMSAFLEgsaspFNIAKT-----HGECVKRK 206
1_pfamImport  64 -KSEGIVHGILVHEMIHMFDFCNNNVDFKNIDHLACTEIRAANLT-HCSFLSAMLQgdvspWNIKAK-----HQECVKAK 136
XP_001846255 134 -RNEGIVQGVLTHEMIHMFDYCRNDLDFKNIDHLACTEIRAANLT-HCSFMSAWTQgdaspFNIKEA-----HQNCVKTK 206
EFA00208     124 -KKPAHVQGVLLHEMIHMFDYCRHDLNFRNLDHLACTEIRAANLA-HCSFMSAWVQgdaslFNIKAT-----HGDCVKSK 196
XP_008202847 118 -KRKGYVQSVLTHELIHMFDYCKNDLDFKNIYHLACTEVRAANLA-HCSFLSAWTYgtaspRNIKER-----HKECVRQK 190
XP_001568808 251 AVIAVDRNP-VCRGf-SERAVDTVFRKCYSDYEPFA 284
XP_002903803 151 AVRSTSSMFpa----eAHDEVDKMFEQCYADLSPFK 182
EEB15206     188 AAQSLMLSR-NLDFdvALMIVLRVFDKCYNDLEPVG 222
XP_015791003 205 AFLSLIASLpELDHseAYKTIDKVFERCYNDMDPFG 240
EFX67841     187 ALGSVMAVRpDVTKeeALAAIDKVFTKCYNDLEPIG 222
EEC20274     207 AVQSVIAVR-GITEqeARAAVDKVFAKCYNDLEPVG 241
1_pfamImport 137 ALESVLAVR-KVTIkeALEAVERVFPKCYRDLEPIG 171
XP_001846255 207 ALNSVLAVR-KVSPeeAIAAVERVFPKCYNDLEPIG 241
EFA00208     197 ALSSILATR-NVSTeeAVDAIERVFPKCYRDLEPVG 231
XP_008202847 191 ALTSVLALK-NVTKdeALEAINKVFPKCYDDLEPIG 225
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