Conserved Protein Domain Family
CCDC28

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pfam13270: CCDC28 
Coiled-coil domain-containing protein 28
This entry includes CCDC28A and CCDC28B. CCDC28B modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation.
Statistics
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PSSM-Id: 463822
Aligned: 17 rows
Threshold Bit Score: 87.717
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CUT99652      35 EEKMLRLLEDFEAGKIVSVGADCPYDKLDAVREQQEELMLLHFELDNKMQSTAgpisgRNRQQARRllmeegrkTSRSNL 114
EFX68198      90 ETALIQLVNDFHSGKLQAFGRHCSTDQMEAIRDQQEKLARLHFELGAQHDVNA-----Q---------------QTSDNM 149
XP_015789957  74 EQGLLRLLSDFHSGKLQAFGQDITFEKMESVREQQEKLARLHFDLNNQQELHD-------TEDGRR--------LAKENM 138
EKC35245      57 EHGLLQLLEDFHCGKLQAFGGSMTFDKMDQIREQQEQLARLHFEMDIQQDMQR-----RDTDEGRA--------AANDKL 123
XP_001630907  15 ERGLLELMDDFNHGRLHAFGRDFTLEKMDKVRELQERVAQQHFELDNAETEAD-----EDEV------------SSARNL 77 
XP_027706417 237 ERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELP-----EDKRKIA----------SDANL 301
XP_014741124  85 EGGLLGLLSDFHSGKLQAFGKECSFEQLEHVREMQEKLARLHFGLDVCVEELP-----EEQKKAA----------ADRNL 149
NP_001139045 118 EGGLLNLLNDFHSGKLQAFGKVCSFEQLEHVREMQERLARLHFSLDSHVEELS-----EDQRKNA----------SDRNL 182
XP_310166    155 ERALLGLLEDFHSGKLKAFGSGCTMEQMTSIREQQESLAKLHFDLGMTEAFTG-----GSNNP--Nndn---elQAQSNM 224 Anopheles gambi...
XP_016970098 110 ERALLGLLDDFHSGKLKAFGSGCTMDQMTKIREQQESLAKLHFELAAAEE------------DSLEhgnefntnKAQENM 177 Drosophila rhop...
CUT99652     115 STLVNKLEALSHSIQ 129
EFX68198     150 NELVSALEHLSQTIE 164
XP_015789957 139 SKLIESLQQLSFSIE 153
EKC35245     124 KKLVDKLHSISSSmy 138
XP_001630907  78 EKLMKNLEGLSSTIQ 92 
XP_027706417 302 DRLLSDLEELNSSIQ 316
XP_014741124 150 DQLLAHLEELSSSIQ 164
NP_001139045 183 EHLLSNLEELSTSIQ 197
XP_310166    225 KKLVQKLEQLSFSIE 239 Anopheles gambiae str. PEST
XP_016970098 178 LQLMQRLEQLSISIE 192 Drosophila rhopaloa
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