3Q2O,4IZO,3ORQ


Conserved Protein Domain Family
PurK

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COG0026: PurK 
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) [Nucleotide transport and metabolism]
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) is part of the Pathway/BioSystem: Purine biosynthesis
Statistics
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PSSM-Id: 439797
Aligned: 685 rows
Threshold Bit Score: 327.031
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3Q2O_A        24 QLGRMMALAAKEMGYKIAVLDPTKNSPCAqVADIEIVASYDDLKAIQHLAEISDVVTYEFENIDYRCLQWLEKHAYLPQG 103
WP_012656596  19 QLGKMMAQSAQRMGFKVAVLDPDERCPARfVAHHFVHAPYNDIAGLKALSRYSDVITYEFENINSEALEVIVKENHVPQG 98 
WP_050899585  25 GVCKELTLNAKRMGFRVITYVTTENNDISqLADFTIVDRLDNVEHLQQFAERCKIILFDPRLMDTRLYAFLNKYTELPQG 104
WP_003641337  19 TNGVGLVIAARNAGINVGVYGDNENTETMeLADFRVVGALNDQQQLQNFAERCDMVTYESETIDASVINFLAAHTRVPQG 98 
WP_015432521  18 QLGKMLAQSAQKMGYRVAMFDPNATSCGFaVADWHTVADFNDADALLAFAKKVDVLTYEFENINGEILQTLHSQTNLPQG 97 
WP_046789818  19 QLGKMMAQSALRMGYRVAVLDPSEDAPAKaTSHHFINAAFGDLEALKSLCGMSDVITYEFENIDAEILHTLVDDYYVPQG 98 
WP_072694315  18 SVARLLALSAKKMGYKVGILDPNAKSSASsIADWHLRAELTNEKAFQDLAMKSDVVLYETEAFHSDYLRMMKRTLPVPQG 97 
WP_077139995  19 QLGKMIAQSAVERGFKVIVLDPSGDAVAKsSSDDFVQAEFDDLESIKQFAARCDVITYEFENINAEVLNHLTEHYNLPQR 98 
WP_118989734  18 QLGKMLAQAAQKMGYRIAMYDPNPDSCGFgVAHAHTVGDFNDRDALLAFAKDVDVLTYEFENINGELLKELEQVAYLPQG 97 
WP_003145311  18 QLGRMLAMSAKEMGYKIAVLDPSDRCCAKiFSDVFIQAEFNDFESVEKLCSLSDVITFEFENIDAASLEKLEKKYNIVQS 97 
3Q2O_A       104 SQLLSKTQNRFTEKNAIEKAGLPVATYRLVQNQEQLTEAIAELSYPSVLKTTTGGYDGKGQVVLRSEADVDE--A-RKLA 180
WP_012656596  99 FETVHILQNRLSEKEAIARSGATVVPYRRIEGPADVDAAVREIGLPLVLKTVFGGYDGKGQLVVTEKAQLEE--A-YNMA 175
WP_050899585 105 SEVLEMSQDRVLEKAVIAGMGIDVVPYVTVVSLDDIYENIREVGFPAQLLPT-WGSPNNG-LILKSRSDIPQ--A-NRLL 179
WP_003641337  99 ADALEITQDRSLERAFFSQLNLNVAPSATIVSLDDVYQSIGSIGYPSILKPIQKGLGQNRQLVIKTQTDIVK--A-ADLL 175
WP_015432521  98 TKLLLTSQDRIKEKTWLASLGVPVVNFAEVQAVQDIENFAKSHGYPVIIKTARFGYDGKGQMKIDSQAELLAqqAeVEKL 177
WP_046789818  99 AKTVLTLQNRETEKQAIKDSGARIVPYEKVETPDAIRAFMETHGAPVIVKTATGGYDGKGQYLIESGADLDS--A-GIPF 175
WP_072694315  98 EDLLSISQDRVLQKAFLESNSLNIAPFATIVSIEDVEEAVQSIGYPCVLKANRTDERYKEHVVLYDESDIPR--T-KNLV 174
WP_077139995  99 DEAIKLLQDRYVEKQTLTKAGVHIATYHFVDSKSSLDEAIETIGYPLMLKTQFGGYDGKGQIKMTSDETYEE--A-LQLI 175
WP_118989734  98 SKLLLVSQNRLREKTWLNEIGCPTAAFCEVSSPEDLQAALANFGYPAILKTNRFGYDGKGQYLLKAAEDIDG--V--PFT 173
WP_003145311  98 AEVLRTTQHRYYEKEFARKLDIPTVDYIYVEEDTNVE-----ITKPYLMKTVRFGYDGKGQKKISSSEEVEP-------- 164
3Q2O_A       181 NAAECILEKWVPFEKEVSVIVIRSVSGETKVFPVAENIHVNNILHESIVPARITEELSQKAIAYAKVLADELELVGTLAV 260
WP_012656596 176 DGNVLVAEKRIALDREISITASRNLQGEVVYFPVQENVHRNQILFSTTVKQ--AHEYRAAAIAEVEKIIHKIHFVGTFTV 253
WP_050899585 180 DRGSYILQSQMTDGMEIVASVVKDMNGHQNIYPMVENVYNDGRLTESIVPARCSDTMQNTIVNLVDQIASQLTFLGTISI 259
WP_003641337 176 DWGTYLLESLIPYDKELSVFGAKSGD-TTAFFPTVENRYRNHELVASIVPAQIDSAVNDEMLRITKEISDNLSYTGVFEV 254
WP_015432521 178 LQQPCIAEAFCPFEFEVSVMVARDQHGSVDFFPVSQNEHCKGILFTSSAPAQLSAEQVANVQEYARKIAENGELVGVCGI 257
WP_046789818 176 DETEFVVEKYITLEREVSLTIARSVSGQVIYFPLQENLHKDQILYRTIVPSR--VDYAEQAQKEAERIMKALHFTGAFTI 253
WP_072694315 175 DSGASVLEAWIPFERELCVAIAKDKSNQVLIYPVIEMMYRNDEFYQSVTPARISEDVVVEVNRIAQIVADNIDFQGVIAL 254
WP_077139995 176 DEAPCVAEQFIDLKTEVSVTATRGQDGQLIFFPLQENIHQDQVLFQTKVPSSF-ISYEDKAREEVQKIVNEVHFVGSFTV 254
WP_118989734 174 DDTDYILEAFVQFTYEASVMVSRSIDGRIEFFPITKNQHRQGILYSSLAGSEVSADVIAKMHDAAKRLAEAGELVGVCGV 253
WP_003145311 165 ---QTLLEEFVKLDKEISVVAVKDKD-EVNIVAVVENEHRNNILYRSKVPTTATKEQENLAIEYTKRILSNFDYYGVLTV 240
3Q2O_A       261 EMFATADGeIYINELAPRPHNSGHYTQDACETSQFGQHIRAICNLPLG-ETNLLK-PVVMVNILG-EHIEGVLRQVNr-L 336
WP_012656596 254 EFFIDKAGkLYVNEIAPRPHNSGHYSIEACDYSQFDTHILSVLGYRLPkQIELHS-SAVMYNLLG-QDLD-LMEHLFpeH 330
WP_050899585 260 KFLINKNr-IFVKEVQPGLQHEQNIFNLATNVNVYEETLRSVCGMSLA-DIKLET-PAVMFDVLS-DQMSdIRTQWLi-K 334
WP_003641337 255 AFFLTKSGnLYVKRIVPAMHQAGYVFERATNISMAEQHLRAIAGLPLM-PVKQLM-PVVAAYFTP-AQESGIRTQWQi-K 330
WP_015432521 258 EFFVKKDGgLVVNELAPRPHNSGHYTMESCNVSQYDQHILAITGRALQ-PIYQHR-PALMVNLLG-QHIAD-LPELFnrY 333
WP_046789818 254 EFFVAEDGtLYVNEIAPRPHNSGHYSIEACNISQFDAHVLSILDHPMP-EVYLHQ-DAVMMNLLG-ADLDrLDGELFt-H 329
WP_072694315 255 ELFTTSTGsLYINELVGHPHQAFHYTIDQGELSQFDAHIRAICGWPLP-QKVSHTrPAVM-RLFNyTQLEqAYTQASi-Q 331
WP_077139995 255 EFFISQDDqLYVNEIAPRPHNSGHHSIESCNYSQFDTHILAVAGYPLP-VIKLLS-PAIMINLLG-QQVIDFGEDVLn-L 330
WP_118989734 254 EFFIDEAGgVMVNEIAPRPHNSGHYSIEACNVSQYDQHILAIAGRSIV-PVQLME-RALMINILG-QHMAD-LPEVFshY 329
WP_003145311 241 EFFIS-EGkVIFNEIAPRVHNSGHITMQSATKSQFRAHIEAICGLKVG-KIENk--ETTLYNILG-QDLDY-YIDVYk-N 313
3Q2O_A       337 T--GCYLHLYGKEEAKAQRK--MGHVNILND-----NIEVALEKAKSL 375
WP_012656596 331 P--EWHVHVYGKEARKENRK--MGHITLLLD-----DDTDTYypiyke 369
WP_050899585 335 SnwNFYLNAFLMNKKEEKTK--IGYVLVSGE-----NTDQILEQIDNT 375
WP_003641337 331 T--NWFFNFYHRTLLQAHRApvAGHVLVEAP-----SVKEALEQIEDT 371
WP_015432521 334 P--QAMFHLYNKGDAKPQRK--MGHFTLLGS-----EQDKAEWLVSLA 372
WP_046789818 330 P--EWNVHVYGKTDRKPARK--MGHVTVLTD-----DLEQTIDALDRD 368
WP_072694315 332 Q--DWKFTFYQSDPTDPNTE--KGHVLIPTD-----NINELLVLLSDI 370
WP_077139995 331 E--GSHVHFYGKSDVRPKRK--MGHVTFLSE-----HLNELEHRVQQY 369
WP_118989734 330 P--EAMVHIYDKGEAKAQRK--MGHFTLLSQ-----GPKHLEDILAES 368
WP_003145311 314 N--GGYLHLYEK-EPRQDRK--IGHINFYGDvilggEHD--------- 347
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