4WFD


Conserved Protein Domain Family
Sas10_Utp3

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pfam04000: Sas10_Utp3 
Sas10/Utp3/C1D family
This family contains Utp3 and LCP5 which are components of the U3 ribonucleoprotein complex. It also includes the human C1D protein and Saccharomyces cerevisiae YHR081W (rrp47), an exosome-associated protein required for the 3' processing of stable RNAs, and Sas10 which has been identified as a regulator of chromatin silencing. This family also includes the human protein Neuroguidin an initiation factor 4E (eIF4E) binding protein.
Statistics
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PSSM-Id: 461123
Aligned: 310 rows
Threshold Bit Score: 30.694
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4WFD_H        11 VRSFSKALDELKPEIEKLTS-------------KsldeqllllsDERAKLELInrYAYVLSSLMFaNMKVLGvkd----- 72  Saccharomyces c...
CBN76772     297 LGEVRAQLGTLTESVQPLVSnvtae---igaskDgl-------vYLRTRQQLL--LAYCMNVCFYmVLKAKGepak---- 360
OWZ02783     230 mSELESTTKELEEVVTPAVLklrpvrrksrqlqMgl-------rYLMTRQNLL--LNYSANISFYlLLRAEGksvs---- 296
EDV23942     407 IEDYKEKMEEIGRTLHPLIQfakck---gllssQgi-------sYLETKYQLL--LNYCVNVSLYlAMAAHEsnsefdvs 474
XP_003387620 228 KNSQKEKFDKLSPKAKLISMl------------------------dQLYHL------YKLNIVFYlTLQANQasvv---- 273
A0DDV4       145 wpELKGILKEITQVGKEIKIlkrnc---kkekgSei------kkYLTIRIELM--QSYFGLLWFYlHLRARTrlsq---- 209 Paramecium tetr...
XP_002261311 244 SLNIQKVYNELKENKRLFQFkdine---hnvnqAdink--ntllYLKKKNETM--LTYIIYITYYvFLKIMNayth---- 312
Q7RBX2       236 SLNIEKVFNEINENQKLFQFknine---ndvspSdink--ntllYLKKKNETM--LTYIIYITYYvFLKVMNcyth---- 304 Plasmodium yoel...
XP_001350292 213 SLNIEKVFNEIKENQKLFEFkdine---knvpsSdink--ntllYLKKKNETM--LTYIIYITYYvFLKVMNsytp---- 281
XP_001019939 158 AQEMNISISEVTDKLFPIMDveeakki----------lpgkgqnFLEIRYEIL--ISYTMCILFYlLLKSKGkitn---- 221
4WFD_H        73 --mspILGELKRVKSYMDK 89  Saccharomyces cerevisiae S288C
CBN76772     361 --ghpVVRRLLSLRGLLEd 377
OWZ02783     297 --dhpVLMHLLLLKKQLNK 313
EDV23942     475 lhehpIISTLLEYRHLiae 493
XP_003387620 274 --dhpVMSRIMELQHMLEQ 290
A0DDV4       210 --hhpIFKKINDLKELIEQ 226 Paramecium tetraurelia
XP_002261311 313 --nhpVLDKLIYMNTIIak 329
Q7RBX2       305 --nhpVLDKLIYINTIISK 321 Plasmodium yoelii yoelii
XP_001350292 282 --thpVLDKLIYMNTIISK 298
XP_001019939 222 --nhpVLDKLTKYKTMIER 238
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