6CAU,3HN7,1J6U


Conserved Protein Domain Family
MurC

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COG0773: MurC 
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Statistics
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PSSM-Id: 440536
Aligned: 944 rows
Threshold Bit Score: 327.408
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6CAU_A        12 IKHIHFVGIGGAGMCGIAEVLANQ-GYKISGSDIKAS-KTTQQLEENGI-KVYIGHEAENIK-NANVLVVSTAIDPENPE 87 
WP_119050991   1 -MKVHFIAIGGSVMHQLALALKRK-GYIVTGSDDEIFePARSNLANAGIlPEATGWFPDKITtSIDAIILGMHAKGDNPE 78 
WP_066402060   1 -MNIHFISIGGSVMHQLAIALKRK-GYQITGSDDEIFePAKSNLEKEGLlPSVIGWFPERITgALDAVLLGMHAKADNPE 78 
WP_013666312   1 -MRVHFIAIGGSVMHNLAIALANK-GYLVSGSDDFIYePSRTNLTKNGLmPEQLGWHPERITeDINAVVLGMHAKADNPE 78 
WP_013613393   1 -MNIHLIAIGGSAMHNLALELHKK-GYQVTGSDDEIFePSKSRLEAAGLlPEKWGWYPERITsRLDAVILGMHAREDNPE 78 
WP_013446504   1 MQRVHFIAIGGAAMHNLAIAICKKnNFQVTGSDDEIFePSYSRLKEHGLlPEQMGWFPDRIHkGLHAVILGMHATEDNPE 80 
WP_014220594   1 -MNVHFIAIGGSVMHQLALALHKK-GYQVTGSDDEIFePAQSNLQKEGLlPKAIGWHPEKITaDVDAVILGMHAKGDNPE 78 
WP_076382057   1 -MRVHFISIGGSVMHQLAIALRQK-GYQVTGTDDEIFePAKSNLEKAGLlPLKIGWQEDMITaDLDAVILGMHAKADNPE 78 
WP_015807398   1 -MHIHFIAIGGSAMHNLAIALHKK-GYQVTGSDDVIFePSAGRLAKYGIlPAQLGWNEDNITpNLDAVILGMHALTDNPE 78 
WP_079555822   1 -MKIHFIAIGGSAMHNLAIALKEN-GAEVSGSDDEIFePSKTRLKKHGLlPETEGWHPEKITkNLNAIILGMHARKDNPE 78 
6CAU_A        88 VKAAIEQRIPIVRRAEMLGELMRYRHGIAVAGTHGKttttsllttmlAEENLDPTYVIGGLLNSTGVNAALG-ESRFIVA 166
WP_119050991  79 LQRARELGLTIYSFPEYIYQESQQKTRLVVGGSHGKttttsmimhvlKNTGKAFDYLVGARLEGFDQSVNIT-DAPVIVC 157
WP_066402060  79 LIKAKELGLPIYSFPEYIYKESQNKTRVAVGGSHGKttttamlmhvlKNAGKSFDYLVGARLEGFNQSVDIT-DAPIIVC 157
WP_013666312  79 LVRAQELGLQIYSYPAYIYEQAKDKTRVVVGGSHGKttitsmimhvlKELGRSFDYVVGAKLEGFETMVKITkDAPLIII 158
WP_013613393  79 LQKAQELGIPIYSYPEYLYEQTKNKLRVIVGGSHGKttttsmimhvlKTCGIEFDYMAGALLEGFDTMVHLSdRSKIAVF 158
WP_013446504  81 LIRAKELGLKIYSLPEYLFQQTRSKTRIVVGGSHGKttttaiilfvqKQLRIDTDYMVGAQIDGFDNMVRLSyESRIAVF 160
WP_014220594  79 LIRARELGLKIYSFPEYIYQESRDKTRVVVGGSHGKttttsmimhtlRKAGKEFDYLVGARLEGFDQSVQVT-HAPIIVC 157
WP_076382057  79 LVKARELGLKIYSFPEYIYQESKQKKRVIVGGSHGKttttsmimhvlQQQHQAFDYLVGAKLDGFAQSVNIT-DAPVIVC 157
WP_015807398  79 LLKAQKMGLKIYSYPEYIYEQTKNKLRVVIGGSHGKttitsmilhvlNYYKGDFDYLVGAQLAGFETMVKITaEAPLIVI 158
WP_079555822  79 LQAAVEQGIKVYSYPEFLYEQSKNKTRVVIAGSHGKttvtsmvmhalKVNNVDFDYMVGAQLEGFDTMVKISkTAKIAIF 158
6CAU_A       167 EADESDAS-------FLYLQPMAAIVTNIDADHMDTYeGSFDKLKDTFVQFLHNLPfygLAVVCGDDANIREILpr-vgR 238
WP_119050991 158 EGDEYPAStlekrpkFHFLFPHIAILTGIAWDHINVF-PTFDFYLEQFVIFINKIEpggLLIYNDTDPVLKKLVeenkrQ 236
WP_066402060 158 EADEYPASaierrpkFHFLFPHIAILTGIAWDHINVF-PTFDNYLEQFRIFINKIEpegYLIYNEGDQTLKDLVasigrK 236
WP_013666312 159 EGDEYLASaidrrpkFLLYHANIALISGIAWDHINVF-PTYQEYVEQFKLFIESIEekgTLVYNKDDKEVQNLVsn-nnS 236
WP_013613393 159 EGDEYLSSpidrrpkFHHYHPDIAILTGIAWDHMNVF-PTFENYVEQFALFTQQITpngKLIYYENDENLRQIAsr-vpA 236
WP_013446504 161 EGDEYLTSpidprpkFHLYKPHIAVLTGIAWDHINVF-PTFEKYVEQFRKFVDLMEvqgRLVYFEDDKNLNEIAgn-lrR 238
WP_014220594 158 EGDEYPASviekrpkFHFLFPHIAILTGIAWDHINVF-PTFDFYLEQFTIFINKIEpggLLIYNETDTVLNKLVtenkrA 236
WP_076382057 158 EGDEYPASalekrpkFHFLFPHVAILTGIAWDHINVF-PTFDIYLEQFRIFIDKIEkdgILIYNETDPVLKELVnshhrT 236
WP_015807398 159 EGDEYLASpidrrpkFHLYKANIAVISGIAWDHINVF-KTYADYVKQFELFIDTIQpggKLIYCKADHDLVKVVde-atA 236
WP_079555822 159 EGDEYLSSpidlrpkFLWYKPDIALITGVAWDHINVF-PTIEEYNKQFELFIDSVRnegYLTWFENDPVLANLIkn-kdR 236
6CAU_A       239 PVITYGfnedndIRAIDVEQdGMRSHFTvlrkGREPLRLTINQPGLHNVLNALAAIGVATDEGVSDEAISRALKGFSGVG 318
WP_119050991 237 DLRYQP------YNIPPHTI-EKGITTV----SIGTHSGALQVFGDHNLMNLYAAWYACRELGVDEVAFVQAMASFTGAS 305
WP_066402060 237 DIHYYP------YSVPSYTI-SNGETRV----CIEGEETALKVFGNHNLLNMHAAWLVCKQLGISAKAFVHAIGSFTGAA 305
WP_013666312 237 NINKHG------YKLPEFTI-NKGVSYL----KTSKGEIALQIFGKHNLSNLAGAFTVCEWLGISREDFYQAIGSFKGAA 305
WP_013613393 237 SVQAIP------YTSFPHYT-EEGTTYL----AGSL-PTPIQVFGEHNLQNISAAYLACKELGIDETAFLKAIATYKGAA 304
WP_013446504 239 DIVPFG------YTTPKHEV-RNGVTYL----ITKYGDVPLKIFGQHNLQNIEAARLACKQIGVTDEHFYSVISEFSGAA 307
WP_014220594 237 DIRYQP------YSIPAHTI-ANGKTTL----TIEGQTGGLQVFGNHNLLNLHAAWYVCRDLGMDAATFVKAISSFTGAA 305
WP_076382057 237 DIRYQP------YGVPAHTI-ENGKTRI----QLEGVEGDMQVFGNHNLMNLNAAWYACKELGMQAADFVKAISNFKGAA 305
WP_015807398 237 DVEKIG------YGIPEHLI-KDGITYL----MPE--EIPLKIFGDHNLMNLNAAKLICAQLNVNNEQFDAAIQSFTGAA 303
WP_079555822 237 NISIEP------YQSLESIA-KNRSTII----RYNNKDYPVPVFGKHNMENMAGALNICLQLGLTADDFLTAMRSFKGAA 305
6CAU_A       319 RRFQVQGEfelgEGNVKLVDDYGHHPKEVEATIKAARQSHPDRRLVMLFQPHRYSR-TRDCFDDFIEVLSQVDQLLLLEV 397
WP_119050991 306 KRLELLAK----NDQTIVYRDFAHAPSKVKATMEAVKQQYPERKLIAVLELHTYSSlNEQFMKEYNGAMDKADAAAVFYS 381
WP_066402060 306 KRLELLSK----NNTTTVYRDFAHAPSKVKATIDAVKEQFPDRKLVALLELHTYSSlNEQFMTEYKDVLNVAEEAAVYYS 381
WP_013666312 306 RRLEYVAD----YAGSVVYKDFAHSPSKVRASIDAVKEQYPNSKLVAIIELHTFSSlNEEFLQEYFDTMKQADEAVVFID 381
WP_013613393 305 KRLQKIAE----QNDTVVFLDFAHSPSKLQATIKAVREQYPRHKLIACMELHTFSSlNAAFLPQYRHTMDLADEAIVFFN 380
WP_013446504 308 GRLQKVAE----TAASVAFVDFAHSPSKLRATVKAVRQQFPDKKLIACMELHTFSSlTDEFLPQYADSMAEADVAFVYYN 383
WP_014220594 306 KRLELLAR----NEQTIVYRDFAHAPSKVKATIEAVKQQFPDRTLIAVLELHTYSSlNEQFMTEYKGAMDPADKAVVFYS 381
WP_076382057 306 KRLELMAA----GKTVNVYRDFAHAPSKVKATIEAVKQQYPTRALYAVLELHTYSSlNEQFMQEYKGAMDKADHAVVFYS 381
WP_015807398 304 KRLELLVS----RNKTNVYKDFAHSPSKLKATIEAVKAQFPDRKLTACIELHTFSSlNKDFLVQYAHTMEAADTAIVYID 379
WP_079555822 306 RRLQQLAE----TSSGVVFYDFAHAPSKVKATVEAVKERFPERNLVTILELHTFSSlNKEFLPQYKDTLQLADEPIVFYN 381
6CAU_A       398 YPAGE-KPIVGADSRTLARSIRLRgqvEPILIDPVEgNLQNIMQNVLQPNDLLLTQGAGNVGAISVE-LAQ 466
WP_119050991 382 GHALElKRMPPLPREKVVEGFGKK---DLAVLNQKE-ELVQWLQSQSYQNANLLLMSSGNYDGIDMLtFAK 448
WP_066402060 382 KHALElKRMPELKKEMVKAGFGKE---NLQVLNQKQ-ELEQWLAERQFDNSVVLLMSSGNYDGMDVEaFAK 448
WP_013666312 382 QNSFRqKNIKPIEALTIKKAFNRD---DIIYFNDAQ-SLEAYISQLDPQGKNVLFMSSGNFGGINLVnLSD 448
WP_013613393 381 PEVVKhKRLPEISSEDVRKGFDDT---QLKVFTDNR-QLLEELTQKNYENSVLLIMTSGNFSGIDIKeLAT 447
WP_013446504 384 PEVVEqKRLAEITPEQVKQAFGGD---KLTVFTDAQ-ALQAALREQQYDNTALLFMSSGNFSGINLTeLAK 450
WP_014220594 382 RHALElKRMPELPAEKVVAGFGKE---GLQVMNDKE-KLMQWLQQQNYKNACLLLMSSGNYDGADMLtFAK 448
WP_076382057 382 KHALElKRMPDLPADIVKAGFAKE---GLQVFTDKD-LLWQWLQQQTYTNASVLFMSSGVYDGLDITgFAA 448
WP_015807398 380 EKTFQhKKMEPFNKNDVQTAFKSN---KLHFFDKPE-ALQDCLLNVNFYRTNLLLMSSGNFGGLDLVkLAR 446
WP_079555822 382 PDVLShKKLATITPKEVANAFGID---EKNIITTAD-QLETYISKTSLNNSNLLIMTSGNLGGIDLKnMVD 448
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