2GD9,3IA4


Conserved Protein Domain Family
FolA

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COG0262: FolA 
Dihydrofolate reductase [Coenzyme transport and metabolism]
Dihydrofolate reductase is part of the Pathway/BioSystem: Folate biosynthesis
Statistics
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PSSM-Id: 440032
Aligned: 945 rows
Threshold Bit Score: 59.8665
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2GD9_A        10 RIILDLAVTLDGFIEg-KNG-E-VD--------WcixDPDXG--FTDFLNQiDTILYGRKSFDLWgqyipknedpdteke 76 
WP_012663231   2 KVILVMAMTLDGKIArdSNH-S-AD--------Wt-gKDDKKk-FVEITKRaGAMIMGSKTFDTIgr------------- 56 
AKM81755       6 EVILIAAMSIDGFIAp-LDK-EsLPst-----aWt-sKEDKDf-FSQKSKEiGLMIMGSKTFETIgk------------- 63 
WP_014729960   2 KVIAVFASTLNGKISlsEDD-K-TE--------Wt-sREDKRy-FKSLTSSvGIVIMGRKTHEAIgr------------- 56 
WP_045087699   2 KVILIMVQSINGKVRliINK-N-QP--------Ws-sQEDKKh-FSKVTKEiGVVIMGRKTFEEIgk------------- 56 
WP_109760290   4 SFTLTVATSRDGFISr-STG-E-PPq------aWa-sAEEQAlfFRDVE-AsDWAIMGRHTHQAAd-------------- 58 
WP_014450659   4 KIRLLAVTDIRGTIAisDDD-R-IE--------Wg-sPEDKRl-FKEITTQsGVVVMGRKTYEAIgr------------- 58 
WP_009512971   2 VVTLLAAQSLDGWITr-HGK-Ggd--------sFt-sEDDKIh-FRQFLREsDACIMGRVTWEASrer-----------l 58 
WP_055048896   9 SIEGHAIVSVDGMIAa-ADG-S-MPpalrneadW-------Ri-FQAALDAaVLVVLGRLGHE----------------- 60 
WP_014956042   2 KVILLMAVTADGMIAr--NSmQlVD--------Wt-gKADKQy-FVDVTRKaGAMIMGSKTFDTIgk------------- 56 
2GD9_A        77 lwK--LvHsKKKYVFSRTQN-----E-Id----------nQ--AIFI-Nd---NILEEVNKLKKNP--GKDIWLYGGASL 130
WP_012663231  57 ----aLpG-RKNIVMTRNRS-----RkSd-----------Gn-LIFT-Dq---PPDLILKGLDREG--FSEVALIGGTQI 108
AKM81755      64 ----aLqD-RVSIVMTSQPErytshNd-------------Pd-LLFT-Ne---TPKEILENLSSQE--VEQVALCGGASI 118
WP_014729960  57 ----aLpD-RLNIVLTRNPDy---yRp------------sEn-LIFT-Ss---TPKELLEDLEKKG--HDEVCLIGGAET 109
WP_045087699  57 ----pLdK-RKNIVLTGEPEkyqklEkTy-----------QgsLFFT-De---KPESLLNRLEKEG--YQTVALIGGPTI 114
WP_109760290  59 -----RpD-RRRIVLSSTVAg---wQrpt--------qlwLdpSDLTpF----DLPALVEAV--HPl--SRGLILGGTRV 113
WP_014450659  59 ----kLpG-RYNVVLSSKAHf----Rce-----------aPd---LVlNg---SVNNVVKILFERG--FTDMCVIGGQAV 110
WP_009512971  59 riEa-RpD-LRRVVLTREPGrhaaeA-RvgvgvdvvgeagRapLAFT-Ae---EPAEVVRRLREAG--LQRCALLGGGQV 129
WP_055048896  61 --RhpNpG-RRRLVLTRSVQa---fErd----------pgDslTQLW-NpagiGIADVLARL---GieQGTVAVTGGTGT 120
WP_014956042  57 ----vLpD-RKNIVMTRNKK-----RtSq----------nTd-LIFT-Dq---TPKQVLKELEAQG--LTCATLVGGSVV 109
2GD9_A       131 ITTFINlgLVDEFRLSIHP-VVLgEGk-PLFI-D------V-Kq--R-------------IN-LKXVNTR-----Tf--- 176
WP_012663231 109 NSLFAQanLIDEIFVTVVP-IFFgRGl-SLFDcE--------Md----------------NQ-LELLGTE-----Ii--- 153
AKM81755     119 YSLFLEkgLVDKMFLTVEP-FIFgEGv-KLFK-G------E-Ie----------------QE-FSLLKQN-----Rl--- 163
WP_014729960 110 FDHFADlgLVNELHITFEP-IIRt-GiaGLgE-T------M-Er--D-------------LD-LSLKEFR-----Kl--- 155
WP_045087699 115 NALFLEknLIDEIYLTIEP-VIIe-GdlSLFS-Y------V-Qg--T-------------YQ-FKLNEVI-----Nl--- 160
WP_109760290 114 HEWFLAhdAIDRVHLTVEP-VAFgTGl-PIFT-D------Q-GtgdP----------------VVVFTSRgyaieSdall 167
WP_014450659 111 FSQFLKsgMVTDLHLTIEP-IILpDGl-NLFS-N------I-Dk--Q-------------FL-LRLEKTH-----Il--- 156
WP_009512971 130 YGAFLAagLVDEISVTIEP-RIFgSGt-PLAS-G------P-Tr-gAdgagavgreflldVR-LELVKAA-----Pl--- 189
WP_055048896 121 FDLFLP--LYDRFVLSEVReLELpDGi-ACFS-KghprlvLpGaglE-------------ARdMELID-Rg--------- 173
WP_014956042 110 NTLFLQenLVDEIHLTIVP-RFFgKGm-SLFN-E------I-Ld----------------TR-LELMEVK-----Ki--- 154
2GD9_A       177 sSg---VVqiVY 185
WP_012663231 154 sDq---SLvlRY 162
AKM81755     164 nEk--gTLllEY 173
WP_014729960 156 gE----AIltVY 163
WP_045087699 161 nNd---AIllKY 169
WP_109760290 168 nAagtrYVtler 179
WP_014450659 157 nSk--gSIyiHY 166
WP_009512971 190 gTgtsgALgvVY 201
WP_055048896 174 ------VLqtQW 179
WP_014956042 155 dEg---HVllIY 163
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