3HUL


Conserved Protein Domain Family
ThrB

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COG0083: ThrB 
Homoserine kinase [Amino acid transport and metabolism]
Homoserine kinase is part of the Pathway/BioSystem: Threonine biosynthesis
Statistics
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PSSM-Id: 439853
Aligned: 452 rows
Threshold Bit Score: 153.331
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3HUL_A         2 SLRIRVPATTANLGPGFDSCGLAL------TLYLTLDIG-AEa---DSWYIEH--NIGGGIPHDET-NVIIETALNLA-- 66 
NP_718967      2 SLTVYAPASMGNVGVGFDLLGAALapidgsLLGDRVTIAaAd----GGVSLTQvgGWAHKLPSNPEdNIVHQCAVFFLka 77 
WP_013344284   2 AVTVYAPASMGNVSVGFDLLGAALapvdgsLLGDRVSVAaAd----QGLSLRCcgAYADVLPPDPAsNIVLRCAERFIer 77 
WP_008306761  11 MLRAFAPASTGNVSLGFDLLGAALkpidgtVLGDEVDLAl-----aDEFSLEVkgAFAHKLPADHDtNIVTRCYQHFVkv 85 
WP_007636333  10 ILRAYAPASIGNVSLGFDLLGAALkpidgsLLGDEVDIEi-----aEQFSLVVtgRFADKLPPDPDsNIVTRCYQHFIav 84 
WP_062482266   9 PVQAYAPASIGNVSLGFDLLGAALkpvdgsRLGDEVKIHp-----aGAFSLEVkgTFAHKLPADSEeNILTQCYRHYHnq 83 
WP_089073247   5 KVSSYAPASIGNFAIGFDIMGLSItpydneKLGDVVEVLeYDesmkVSNCLVVsgNYAKSLPELPNkNIVYHCLQAFNei 84 
WP_108603269   2 AVTAYAPASTGNVSLGFDILGLALkptngaLLGDRVTIFaTa----DEFELSLagRFANKLPSDAKqNIVYDCFVGFQae 77 
WP_115718684   8 VLKVFAPATSANLNVGFDSLGVALapikgePIGDIFGIEe-----aAIDSLDVfgAYAHEL---KGtNIVEKALWRFRel 79 
WP_127020440   2 K-SYFAPASTGNFSVGFDLLGAAFepvdgsLFGDELRIHsEq----SELSLTLtgRYVHQLPKDTDdNLVLKCFYAFEka 76 
3HUL_A        67 --P------NLTPHHLVMTCDIPPARGLGSSSAAVVAGIELANTLAEL-----NLSKEEKVRIAAEIEG------HPDNV 127
NP_718967     78 lgK------ENRGVALTLEKNLPVGSGLGSSASSVVAALYALNEHFGC-----PYDKQALLELMGEFEGkisgsvHYDNV 146
WP_013344284  78 lgL------EGVGLKLTLEKNLPIGSGLGSSASSVVAALAALNAYFDS-----PLDDQALLHLMGELEGeisgsvHYDNV 146
WP_008306761  86 mgEkg---vELPAVRMILHKHLPIGSGLGSSAASVVAALHGLNEFYGQllgnvPFNQHELLLIMGELEGqisgsvHYDNV 162
WP_007636333  85 leQqghaksAIPLLKMTLHKHLPIGSGLGSSASSIVAALHGLNQFFAEyfgkiPFTENELLLIMGELEGqisgsvHYDNV 164
WP_062482266  84 aeQqg---hQLEPCAMLLYKNLPIGSGLGSSASSVVAALDGLNTFYGE-----LFDQQRMLLMMGELEGqisgsvHYDNV 155
WP_089073247  85 lkKkn---iEQKNIQLHLIKNLPIGSGLGSSASSVVASLSALNYLYNK-----LLNPDELLILMGKMEEkisgtfHLDNV 156
WP_108603269  78 laAqg---kAIPAVNMQLEKNLPIGSGLGSSASSIVAALAALNAFFEY-----PLDKETLLRLMGKLEGqisgsiHYDNV 149
WP_115718684  80 taI-------KTPVAMHLEKGMPIGSGIGSSAASVVAAVMGINRYFGS-----PLDAEEEKSLMAELEGelsggvHWDNL 147
WP_127020440  77 idR------TLPRLQLELVKNLPVGSGLGSSACSIVVACYAFNDYFGK-----PLDDYQLLQLMAQLEGgvsgsvHYDNV 145
3HUL_A       128 APAVLGNWVVGAKLdGEDFYVR-HLFPDCALIAFIPKAELLTSESRGVLPDTLPFKEAVQASSIANVMIAAILRNDMTLA 206
NP_718967    147 APCYLGGMQLMLNV-PGAICEAiPSFKQWYWVVAYPGISLSTAMMRKLMPEQYDKSVVIDFGRYLSAFVHASYQQNAQLA 225
WP_013344284 147 APSFLGGLQLMLPE----RAQPvPSFDNWYWVVAYPGITLSTAKMRALLPKQVEMATAIRFGQQLAAFIDACHRQDEETA 222
WP_008306761 163 APCYLGGLTLMAEQ-ADTLALQlPTFKHWYWVACYSGITVSTAAARDILPKQVSMPNTLKFGRQLAVFIDALYRQDEKLA 241
WP_007636333 165 APCFLGGLTLMAEH-KEQVALQlPMFENWYWVSCYSGMNVSTAAARNILPKQVSMSNTIQFGRQLAVFIDALYRKDEKLA 243
WP_062482266 156 APCYLGGLVLMAEQ-ADNIAINlPVFEDWYWVACYSGIKVSTAEARRILPQQVALKDTLTFGRQLGVFVHALHSGDRKLA 234
WP_089073247 157 APSFLGGLQLILSN-G--LSKRlEIFDSWLYVIAYSGEKINTIDARSVLPQNLPLRAHIEHTKNLSSFLVGLQTKNENLV 233
WP_108603269 150 APCYLGGLQLMVES-EDKVSITlPCFDDWYWTICYSGASVSTAAARDILPKEYSTKTTIDFGRQLAVFTHALYAGDKPLA 228
WP_115718684 148 LPCLLGGLCLHD--------AKlPVPEEWVWLLAYPGIRLETKAMRAILPKAIPLSDATAQASRLGRFVDALYRSDPQLA 219
WP_127020440 146 APSFYGGLLLMLPD-SPLLCRAlPWFEHWQVVLCYPGTVLSTKEARAVLPQQLTLKHSIAFAGMLSRFISALYAKDETEA 224
3HUL_A       207 GEMMErDLWHEKYRSQLVPHLAQIRDVAKNQGaYAACLSGAGPTVLVFAPRNl-ANK----LQTSLQTl--EidadVLLL 279
NP_718967    226 IQVLK-DVLAEPYRAAAIPGYDNARAALAELGmLTTGISGSGPTLFSVTDDLatANAakawLEANYLTdagGf---AHVC 301
WP_013344284 223 LAMLQ-DVLAEPHRAAHIPGYQAARGHLSDLGcAAVGISGSGPTLFAVARNRaqAEAaaeyLGQHYIMnerGl---VRVC 298
WP_008306761 242 VSMMT-DVIAEPYRKSLLPYFDESREFAMQNGaMAFGISGSGPTVFAVCDNLeqAQTistwLEENYIQndtGf---SHVC 317
WP_007636333 244 AAMML-DVIAEPYRKSLLPRFDESRAFAEQHGaIAFGISGSGPTVFAVCDNIenAKIinqwLTYNYIQndtGf---SHIC 319
WP_062482266 235 AAMMQ-DVIAEPYRKKLLPGFDEARAFAIQQGaLAFGISGSGPTVFAVCDDLarAEKinqwLSAHYIQnadGf---SHIC 310
WP_089073247 234 LDNIK-DVIVEPNRRVLMPNLVYAREELKKIGcLNTNISGAGPTIFNIVKDIktANTvktwLEQNYINkknGf---VKIC 309
WP_108603269 229 ASMIK-DVLAEPYRKSLLAGFDDARAYAESQGaLAFGISGSGPTVFAVSESAeaAENirawLQDNYCQnefGf---SHVC 304
WP_115718684 220 AALMF-DPIVEPHRAPLVPGFGPLKDQLINKGaLSCGLSGSGPTMFAVFDNMasAKAal-tEAQHWVApnqGf---AHLC 294
WP_127020440 225 FAALQ-DLVAEPARQHLMPELLPIREKLTAQGiGHVGISGAGPTIFAVCQNDaqAKFsadyLQQYYAKnsdAi---TTVC 300
3HUL_A       280 DVEGSGAEV-----FRE 291
NP_718967    302 RLDEQGTRR-----VD- 312
WP_013344284 299 QLPQQGIQIwqedvINA 315
WP_008306761 318 QLDEQGAVA-----KDI 329
WP_007636333 320 QLDTSGASI-----SHS 331
WP_062482266 311 QLDPQGSTA-----KKV 322
WP_089073247 310 KLNSGGAVY-----TDS 321
WP_108603269 305 KIDNDGTAI-----TED 316
WP_115718684 295 RVDELGARF-----LES 306
WP_127020440 301 HLARQGARAl------- 310
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