Conserved Protein Domain Family
Fra10Ac1

?
pfam09725: Fra10Ac1 
Folate-sensitive fragile site protein Fra10Ac1
This entry represents the full-length proteins in which, in higher eukaryotes, the nested domain EDSLL lies. Fra10Ac1 is a highly conserved protein, of unknown function that is nuclear and highly expressed in brain.
Statistics
?
PSSM-Id: 462858
Aligned: 57 rows
Threshold Bit Score: 133.43
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
EED88579               65 SDFEQLRAHFQFVLPTDDDDNDvnatsnntsgygsTWQQRMVQHYHSHLYKEYVLADLSHVLSkGKVGLRWRTENEVFSG 144
XP_006955776           35 TEFDLIKQNHKFLKDEDLYDSDeevket-teevtdPYAQKLSDKYYDSLYKEFAIADLKHYKT--QISLRWRTKQEVVDG 111
XP_007403156           19 TEFDILKERHKFLRDNTEENER-------------TWEDKLARKYYESLYREYAVCDLKHYKS-GNFSLRWRTEEEVISG 84 
EPT01631               12 SEFEILKASHKFLREDGEADESk-----------lPWDDKLAKKYYDNLYREYAVCDLKHYKS-GNFALRWRTESEVVCG 79 
EMD34006               20 TEFDVLKASHRFLREDEPEGGL-------------TWEEQVAKKYYDNLYREYAVCDLKHYKT-GNFALRWRTENEVVSG 85 
XP_007845380           18 TEFEILKASHKFLREDDEEEGAq-----------lNWEEKLASKYYANLYREFAVCDLKHYKS-GNFALRWRTEAEVLSG 85 
WGS:AAWC:PGTG_19496.3  28 TELDILIERHQFIRDCDEQNL--------------SWEDALAKKTYDQLFKELAVCDLSRWKE-GKVAMRWRTANEVVDG 92 
OAV95765               28 TELDILIERHQFIRDCDEQNL--------------SWEDALAKKTYDQLFKELAVCDLSRWKE-GKVAMRWRTASEVVDG 92 
CAZ82597               44 NERDILEDHHQFIRTDEEAD---------------TEEKRIAKSYYDKLFKEFAMVELARWRE-KQIAMRWRTKQEVLDG 107
XP_011107865           57 TERDLLEEEFQFLRDDEGDAGGs-----------nDTGKEIAKKYYDNLFREFALIDLSRWRE-GQVALRWRTKQEVLQG 124
EED88579              145 RGFRTCGNLKCegvstdqlstagddDSYSakirsalgvgvaenggkvpigvvlpsegasraletylqscsneassygeqs 224
XP_006955776          112 VGETSCANIRC--------------MTREs-------------------------------------------------- 127
XP_007403156           85 AGESTCGNTRC--------------PLHLprnidp--------------------------------------------- 105
EPT01631               80 AGETTCGNTRC--------------ALHEqravd---------------------------------------------- 99 
EMD34006               86 AGETTCGNTRC--------------PLHKehged---------------------------------------------- 105
XP_007845380           86 AGETSCGNTRC--------------KLHEptadfddfa------------------------------------------ 109
WGS:AAWC:PGTG_19496.3  93 KGHFTCANLRC--------------IHHElglkspprslskkahplgafanfe--------------------------- 131
OAV95765               93 KGHFTCANLRC--------------VHHElgpktpprtlsrkphplgafadfea-------------------------- 132
CAZ82597              108 KGQFSCANLSC--------------RNHRstlden--------------------------------------------- 128
XP_011107865          125 LGQFTCASLTC--------------PGHLpstedsaefsld--------------------------------------- 151
EED88579              225 gnhrsdhkkkhkkyrdkrsnyspqslerkeekrlsqlaygiGLHDYevdfayvEHGKKKRELVKVRLCMRCAPLLFV 301
XP_006955776          128 -----------------------------------------KLIPFelpfnykENDIAKNAEVKVVLCRHCSKKLSY 163
XP_007403156          106 ------------------------------------ddpcpPLKTLelpfsyaEDDQSKSALVKVVLCDKCCKNSGW 146
EPT01631              100 -------------------------------------elrpSLKTLelpfsyvEDGAAKFALVKVVLCDRCLKKLMW 139
EMD34006              106 -------------------------------------eiqpALTTLelpfsyvETGENKFALVKVVLCEKCVKKLMW 145
XP_007845380          110 --------------------------------engrghkssNLATLelpftylEHGESKSALVKVVLCEKCVGKLMW 154
WGS:AAWC:PGTG_19496.3 132 -----------------aqhsfipleefsragerseltpqiPLQELqtsfgylEHGVRKLAEVQLNLCKRCAKKMNS 191
OAV95765              133 -----------------qrsfipleefgrdsgrpepssskvLLQELqtsfgylEHGVRKLAEVKLNLCKRCAKKMNS 192
CAZ82597              129 ------------------------------------pdeegGLRSVelnfeyaERGEKKHALVTARVCEECADKLRY 169
XP_011107865          152 ------------------------------averdvnegtvNLETFemnfgyvEKGVKKNALVKVCVCDKCAGKLRK 198
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap