Conserved Protein Domain Family
HamA

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pfam08878: HamA 
HamA
Hachiman antiphage defense system has been described in Ralstonia solanacearum species complex (RSSC), and is composed of two genes, hamAB, which encode a protein of unknown function HamA, represented in this entry, and an helicase (HamB). Only one strain (KACC10722) from phylotype IV shows this system complete and both genes are organized in an operon.
Statistics
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PSSM-Id: 378078
Aligned: 53 rows
Threshold Bit Score: 85.4468
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_000834167    52 KELAETLFLELVHYCIPHpviakrkalsqtegkdEArlYSELAREARSLFMKyklestltikkgETQEKFEQrv------ 125 Enterobacteri...
WP_012858686    39 NNWALGLRNNYIEEHLLE----------------QAisGTGLAKKEYLEKMI------------FPNPRVPQ-------- 82  Streptobacill...
WP_009835993    28 KLLEDYLVGKLASCYISQ----------------EK--LEERANQTGLAYSE------------LIANKIPD-------- 69  Marinomonas s...
Q0YV14          49 DQFVAAMREFLRTHHSRP----------------EDleRDRLRREAYARQGLt-----------LPLTRFPT-------- 93  Chlorobium fe...
jgi:Rpdx1_0865  56 ERLGYKVAAKIFSEAMPQ-------------------------------------------------------------- 73 
WP_004823893    22 DELKDKIKEQLVEICHGE--------------------YALVSGLNYHSFDEtv--------keLVNHRIPS-------- 65  Peptoniphilus...
USDA:Abu_1332  144 FDMNELLFNEINNKIFNT----------------EN--VLKVASTYTPKTKYtd---------kQKKQKYFDalksigfi 196
EEX19929        50 IDVANIIYNGIVDYAYSD----------------NE--IDLTQLDKLQIRAL------------LSKLKFDPn------- 92 
WP_004611816    54 EDFLVDLMDTIVDWIYSA----------------DK--YAVLKEKETKKGKSeatah--asvqrRARDKFRKgs------ 107 [Ruminococcus...
WP_011805630    51 EDFLRELKNTMCAWVYSK----------------NK--YNKIFQDEMAVRGAdvqnvs-shlqfLVRERF---------- 101 Acidovorax sp...
WP_000834167   126 ------kNANLRYG---EVGELI-SYCIAIHFLKAAQ----LVSKMALKTS-SEMPVFGLDGIHATVDDEGTL----TVF 186 Enterobacteri...
WP_012858686    83 -------GAATMSG---EFGELL-VYDYINYVLEYYV----PRIRYFNKVN-PNTPIHGSDVIGYKMESYNKRskndKLL 146 Streptobacill...
WP_009835993    70 -------KGSVMSG---DFGEIFtLYFLDRQYKDDLK----LIKKWRYKQD-RKKAAPHSDVVLFNIGDLNNPseddFVI 134 Marinomonas s...
Q0YV14          94 -------NPKTRKG---NWTEVL-LCEYVTASCNADL----PVYRLRYNPN-VDQSMKGDDVLAFDLNAHPI-----RII 152 Chlorobium fe...
jgi:Rpdx1_0865  74 -------TPKGRSG---DLGEIL-ATELVEEEIGLRV----PVRRLRYKDG-RNMAMRGDDFIGAGYDAAGE-----KLW 132
WP_004823893    66 -------NINRKVG---VIGELL-LNVMIREFTDIKI----VSPFFNLEER---HVKKGFDIIAVDSNK--------DLW 119 Peptoniphilus...
USDA:Abu_1332  197 sntgvdtSHTTLHG---DIGEFL-MHIMLSKFLSDKSvkkyIYPKLVFKTS-PKMPVYGNDGTIYIEDTK-------EIY 264
EEX19929        93 ------aSESIQLGygfQ-GEVM-LHLLLSHFFHAEK----ALARGYLYSAlENAETKGYDSYLMIENNETI-----FLL 155
WP_004611816   108 ------gNTLLVQG---QFGELL-LFHFIQKCMKAVP----LLRKMKITTS-SQHERFGADAIHYKVENGKN-----III 167 [Ruminococcus...
WP_011805630   102 -------RKGYPQG---QFGELL-LFNFLQHFFKAAP----LLRKMPITTN-QAIERHGADAIHYRPQGGKN-----LVF 160 Acidovorax sp...
WP_000834167   187 YLESKM--TRE---FTSG--------SEQFSKSVSGFEn--DRKSRRNEYRILQDLSNLEslegeERKKAVQYFDpy--- 248 Enterobacteri...
WP_012858686   147 VAEVKT--RSS---ISGNktkictniVTDAITDSNKDRv-rVGESLNAEKLKLLNRGRIK-----EANIVERFQNk---- 211 Streptobacill...
WP_009835993   135 CAESKQkaTAS---AFDP--------ISSAISGYESD----RTGRLAKTLVWLKEKAIDEgn-qdDLTLASRFADe---- 194 Marinomonas s...
Q0YV14         153 VGEAKFrgASS----KKA--------VTDIIESLERS----FRGGLPVSLQFVANRLIVE-----RNEALGRRIEeca-- 209 Chlorobium fe...
jgi:Rpdx1_0865 133 LLKGEA--KSNkvlGKAT--------VTNARKVLNRD----NGRCTPDSLLFVANRLLESnd--pDDNALGRSLRdev-- 194
WP_004823893   120 IIESKAgeLGK---LKTSteka-cerINAAKRDLNTRLnmhNSQLWLNAVNSVRSALDDTs----EKNTIVNILNknss- 190 Peptoniphilus...
USDA:Abu_1332  265 YLEAKF--FSD---LDSA--------VNRAVKSLKAHNe-vCEENITHKIELFRNIKTDE---------LNEIIE----- 316
EEX19929       156 FGEAKF--YLDg--YKRS--------LDSIFNNIDKAL---SDSYFNRNFIAMENHYEHIe----PKSRIREIIDqwrtd 216
WP_004611816   168 LGEAKT--YSSkykFNAA--------FEDALNSILNTY---KTHRDELNLYVHEDFLDEE-----MNEIAEEYLDk---- 225 [Ruminococcus...
WP_011805630   161 IGEAKT--YSSkyrFKAA--------LDDAVDSVIKSF---LNLSNELNLYINDDFIEDS-----LREIAGKIKRn---- 218 Acidovorax sp...
WP_000834167   249 -------ssESSNVRERFVGIIVYNEEAyknkiaiddesplsihldhFKKSYIGSYKDKVKIITEdlska--gatpqKCR 319 Enterobacteri...
WP_012858686   212 ---------TDNPYTLDFFAVAVMDSDL-------------------YSDQVVLDVVNSQHENVK------------CTS 251 Streptobacill...
WP_009835993   195 ---------LNIRYSKIYRAVAIVDRAF-------------------LNDEITKDINLPEKTH--------------SFE 232 Marinomonas s...
Q0YV14         210 ------dlfVRNRLRIDHVGLLASN------------------------HLAPTHVEKNAISSLR------------RIA 247 Chlorobium fe...
jgi:Rpdx1_0865 195 ------glkSLRADRIDHMLFTVSGNGph----------------asLKEDLDATSTNRDHYVVN--------------- 237
WP_004823893   191 -----sclsNDKNVILGGIVFCIFNSTIds---------------ieLRKLHDSILSSNKFSKLK--------------- 235 Peptoniphilus...
USDA:Abu_1332  317 ---------IDENVTENLVLFLICDdy------------------tdYEDILDVIRKNKKLTKLKkd---------yNIL 360
EEX19929       217 plinmaeeaKQHNMNLVYPMLVIFDDKMtey--------------dnLIMDIISYIQTKYNAVQPtltip--ytiffCFF 280
WP_004611816   226 ---------RLQNVEIHLVSIIVYDETKkinlt----------nendIRRQIEEIIEMRYRDFDNskipikeniilkRMT 286 [Ruminococcus...
WP_011805630   219 ---------TLPNVVYELVCIISYQENEknktgnc-----qseieksIEDAVTSHILKHQGALGHfdqg-----tlgKIH 279 Acidovorax sp...
WP_000834167   320 AYIFAL 325 Enterobacteriaceae
WP_012858686   252 ILIIHS 257 Streptobacillus moniliformis
WP_009835993   233 IIVIGI 238 Marinomonas sp. MED121
Q0YV14         248 VISMTL 253 Chlorobium ferrooxidans DSM 13031
jgi:Rpdx1_0865 238 ---IHV 240
WP_004823893   236 LIAIQK 241 Peptoniphilus lacrimalis
USDA:Abu_1332  361 LFVLPI 366
EEX19929       281 MWIIVV 286
WP_004611816   287 YIVFPI 292 [Ruminococcus] gnavus
WP_011805630   280 FIFFPF 285 Acidovorax sp. JS42
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