2MLX


Conserved Protein Domain Family
Tig

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COG0544: Tig 
FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) [Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 440310
Aligned: 847 rows
Threshold Bit Score: 168.77
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2MLX_A        12 MQVSVET-TQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAI 90 
NP_662811      1 MQKNITN-VSEIAQELEIILTAEEYQPEYDQQLEEARKSVRIKGFRQGHVPVGMLKRIIGPSIEAEVAEKMASKYFAAIA 79 
WP_012844894   1 MQTEIKE-ISSVEYELRLHVPAEELQPELDRLLRQIRAHVQLKGFRPGKAPLSLVKKLYGDEVALELAERKIREALEQAV 79 
WP_083851400   5 LDIQFNK-INPNHGVISITLHEFDYKSAVAKQFKHYAQTVRLKGFRLGSVPEDLIKKMYGSSILAEELHKIAVASLKNYI 83 
WP_096685807   1 MNISVENdIKNSTSTISMTLYKEDYQEAVSKVLQSYRRQSNVPGFRKGHLPINIIEKKYGKHALIEEVNKILSVELDKYI 80 
WP_012499600   1 MESKFKQ-LSDTEQELEISFSPDEFQPELDKQYKLAQAKAHLKGFRKGKAPLQMIKKMLGRDIQYQVVEELAGKNFESVA 79 
WP_012506499   1 MQHTIKN-VSETEQQLEIILSAEEFNPEVELEIQDAKKNIQIKGFRKGHVPVGLIKKLMGPAIEASVAEKLASKYFGEIA 79 
WP_066205158   1 MEFKLDK-QENSYGLLTVNVTEADYMTEYKSKLKQYAKTANMKGFRPGKVPFSMVEKMYGKQVKMDTFNETVGKAVDTYL 79 
WP_043552741   1 MDTTLSK-ASPVEYELDLHATADELEPKLKEALNAQRKNMDVQGFRKGKVPLGLVKKMHGEAIGYRVAEQFVQEAFEEEV 79 
WP_011746075   1 MQKNITK-VSDTEQELEIILTAEEYGTEYNQELDEAKRTIQVKGFRKGHVPTGLIKKLAGPAIEASVAEKMASKHFGTIV 79 
2MLX_A        91 -IKEK-INPAGAPTY------VpgEYKLgEDFTYSVEFEVYPEVELQ-GLEAIEVEKPIVE-VTDADVDGMLDTLRKQQA 160
NP_662811     80 -EEEK-INPASRAQI------EsyNY-EdGKLTIKISYEIHPEFELK-DFSEYTFTQAEYT-ISDEDVDREIKLILRGHG 148
WP_012844894  80 lEPGT-YRVIGRPRV------LrlDYKPdADLHAVLRFGVRPEFELK-PLDQETIPHLVHQ-VTDEEVEEAIKRLQKEEA 150
WP_083851400  84 -LQEH-ISIFMDP-Ilvt-plQeiHLKNqDTFTFSYEVGLIEKRPIVfE-PNISITEFEIDhVESKLVDEFLEGLQMVHG 158
WP_096685807  81 -KENN-IDVLGNP-Ill---eDniNWDs-DILDFRFEIASVPGFELVmP-KDGKITNYKIK-VSEEDIDKRIEEIALMYG 151
WP_012499600  80 -KEND-LKLVGQAKI------RhyELAEnEKLSIYLIYEVHPAFELK-PFNEYEFKKAEYQ-VSDETVEKELKKLLQSKG 149
WP_012506499  80 -EKET-IKPASRAQL------DnfSF-NdDQLTITLSYEIHPEFELK-DFSGYSFVEDLYT-VSDEDVQNEINLILKGHG 148
WP_066205158  80 -KDNN-VKPLFQP-IykgdfiTpeQLGa--DQTVEFEL-LLPEFELKtE--GVSADTFNLT-VTDADVDNTIVKLKESYP 150
WP_043552741  80 -EETDaIEPLGQPTL------VdlDYELdADLQATLRFGVRPEVELE-DLSSVEITMLDPE-ITEEDVEDEIERLRKEEA 150
WP_011746075  80 -DEEK-IKPASRAQI------EsvSY-EgDELKIKLSYEIHPVFELN-NYSDYTFTKARYT-ITDEDVQKEIDLILKGHG 148
2MLX_A       161 TWKEKD--GAVEAEDRVTIDFTGsV--D---GEEFEGG-KASDFVLAMGQGRMI-PGFEDGIKGHKAGEEFTIDV--TFP 229
NP_662811    149 TMVTSE--DAAAEGDTVIGDVTK-LdaD---GADIEGS-KNENHHFNLEYLPAD-NPFRMALEGKKAGDVVDVTV--KPK 218
WP_012844894 151 ELVDLPadTPLGAEDYAVVDLQR-L--DeatGAPIIGE-KEEGVSFFLDDPRLR-EELRQALLGKKAGETVRVDL----P 221
WP_083851400 159 QVAHLE---ESAMDTMLYGTLVD-----------STGAiG-ID--IRISIMHIP-EHLREELVGRRVGQKVMLTEesLKH 220
WP_096685807 152 KGQPTK---EINNKTIVKGIISW----------NTDKNhS-VE--STIFMSNLI-EKRIKDFEGAKVGALIHLETenLFK 214
WP_012499600 150 NMVAVE--GAAAPTDIVIGDVQK-LdaD---GTAIVGE-RQENQSFRLEYMKDD-SPFFTALNGVNKGEERRVEV--EVK 219
WP_012506499 149 TLVSVD--EAATSNDTVIADLIK-LdaE---GKEIEEQ-KTENHHFNLEYLPED-NPFKKALTGAKAEETVNVDI--EPK 218
WP_066205158 151 TKKDAE---EVAQADVVTATFKA-----------EAGEyS-KEg-AAFDVDDKLaEGIADQFIGKKVGDVVTLDIdtMYE 214
WP_043552741 151 DLLPLEe-EAAEDTDYVNIDLQR-IdpDt--DTPIIGD-KDEDLTFFLDDDRLK-EELREALVGQKAGDTFRVEL----P 220
WP_011746075 149 SLATVD--EAALGTDTVIGDVEK-LdaA---GEPEEGG-KTENHHFNLEYLPED-NPFRISLEGAKAGETVNVAT--TQK 218
2MLX_A       230 E-E------YH-A-ENLK-----------G-----KAAKFAINLKKVEERELPELTAEFIKRF-Gv-eDGSVEGLRAEVR 282
NP_662811    219 E-E--------------G-----------G-----ETNRFRIEIKEVKHLELPELDDELVKEI-SqqrFEKVEDFRNDIR 266
WP_012844894 222 HgD-----------EE-T-----------Gep--aHAHRYEVRVRETKRRELPALDAEFIQKI-ShgqVSDEAGLRELVR 275
WP_083851400 221 hfp----alLGvSfSDFI-----------AfkkyeSAWPATFTIDKIVQVVPMAIEPALFDLVlGkgvAHSENEFREAIA 285
WP_096685807 215 N-EnhlaiaLNkKnEEID-----------Dii--dDISTISLEIKELLIHQPAEIDKDLLEKIyPdksVSDIEGLKNKVI 280
WP_012499600 220 EeD------VP---EE-------------N-----KKQTFLISVKEIKRMELPELTDELVKEL-SrgkNETVQDFRDELR 271
WP_012506499 219 E-E--------------------------Ge----EKVSYEISVKEVKRMELPELTDELLKEI-TqekFDSIDAFTQDVR 266
WP_066205158 215 D-SkrlglfLGt--EDAD-----------Qf-----TGNFSIEITKITRNHEPELDQDFFNMViGpdkASNEEEFRAELK 275
WP_043552741 221 Q-E------HP-A-HEHAghghphehegdG-----EDRLYEVTVNDVKRRDLPPLDEEFVRRV-TegeLDDLEAFRNDIR 285
WP_011746075 219 --D-------P------N-----------T-----PVVSYRITVKEVKRLELPELTDDLVKEI-TrqrFETVADFTADVR 266
2MLX_A       283 KNMERELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGN------E--KqALELPRELFEEQAKR 354
NP_662811    267 LQLQAHFSDKSEYDLLEAISSKLIEEHPVPTPSAMVAHFQNILLENAKRQVGGQ------FpkGfDEREFFNAMKPNAEK 340
WP_012844894 276 KELQARWDQESRELLEQEIMHRLLTLHPIPVPESAVEMVLDEFVEDVRQR--NNgrlpegF----DETAFRHANRALAEQ 349
WP_083851400 286 KIILFDKRAEARHAFYQDLQEALLKDNKVDLPEAFLKRWLMVNNP----EA--------------TLEAI-EEYYDAHKE 346
WP_096685807 281 EEFENYYKTTSDIYLFNQVIEYITESTKISLPKDFLIRSLKSNTS---DDL--------------TEEEM-LSLYEREKI 342
WP_012499600 272 KQIEAYFTNKSEEDLMESVAQKFLEENVFTAPSSLIKMYEDMLLDNAKRQIGg------aFppGfDETYYRAEIRPNAEK 345
WP_012506499 267 QQLEEHFSGKSEQDLLESISSKLIEENPVATPSAMVDSFENMLIENAKRQFGGN------FpaGfDDTELRASMRPNAVK 340
WP_066205158 276 KTIGEVNQQAIDNVTNENVRTALVEANPIALPAELLKTVFKQNNP----KS--------------TDEEV-ENNIGKFEE 336
WP_043552741 286 ERLQEAWDERAREMAQGEVIDKMLELHPVPVPESVIEGYLDSFVKQVEEE--NDgelpedF----DEEHFRQRNRRDAED 359
WP_011746075 267 IQLEEHFGMKSDEELLESISSKLIEENPVSTPKSMVASFANMLVENAKRQFGGK------FpkGfDESQFTESIIPNAEK 340
2MLX_A       355 RVVVGLLLGEVIRTNELKADEERVKGLIEEMAS-A----Y-E---D-PK-EV-I----EFYSkn-kE---LMDNMRNVAL 414
NP_662811    341 HARWLLISQKIAKENNLEVTDEDIKAFAEKEAE-K----EpS---L-TV-DQ-L----LNTYls-tE---FKDYIIDTIL 401
WP_012844894 350 QARWTFIFDKVVETFGIEVTEADIQAFFEKQADpE----S-G---L-SA-EQ-L----RQFYesvpG---LIDQVRSRLL 411
WP_083851400 347 DLRWELLLSNIVRQNNLAVTTSDVVDETKRAYVdYaa-hK-GlqlEeN--DAaIhtgaISFLqg-sEgskYYSKLHNQLS 421
WP_096685807 343 SIKNNLIFDAIAKKYDINVSINEVKDHFKDNILkImggdL-Ad-dQnN--QDmIenmiKRIMed-qE---KVNSVSIKIF 414
WP_012499600 346 HARWMLIRNKIAELNGIEVSDDDIKALAEKEAK-L----T-G---A-EAtEE-F----VNTYfs-eQ---YKPYVIDTLL 406
WP_012506499 341 HAQWMLISQKIAETNNLEVTDEDIKAYAEKEAE-K----NpS---V-KA-EE-L----INTYms-tE---FKDYMIDTIL 401
WP_066205158 337 AVKWRAISDAIAETAEIKVEKEDVEAAALEQIKaQfg-nFm----GdE--DDrMgefvQNYLta-eNg-kYFEQTYEQVY 407
WP_043552741 360 QGRWMLIRDQIVEEQDLEVSNEEIQTFFAEQSGgE----E-Q---V-TA-QQ-I----EQFYqtmpQ---MMEKVEQQIL 421
WP_011746075 341 HARWLLISQKIAELNNVEVTDEDIKTYAEKEAE-K----StP---E-QK-EE-I----MSTYqs-tE---FRDYIADTII 401
2MLX_A       415 EEQAVEAVLAKAKVT 429
NP_662811    402 KEKIYDVIKSKVTIT 416
WP_012844894 412 HQKVFDTLAERFKLE 426
WP_083851400 422 RDRAINFIKKQITIV 436
WP_096685807 415 NEKLLTSFNENLKFK 429
WP_012499600 407 RDKIYEFIKANTKIE 421
WP_012506499 402 KDKIYGIIKSSVTIQ 416
WP_066205158 408 NEKIFGAAKEKVSLN 422
WP_043552741 422 SDKVYDFLFDRLDVE 436
WP_011746075 402 KDKIYDIIKSQVTIT 416
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