Conserved Protein Domain Family
AsnB

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COG0367: AsnB 
Asparagine synthetase B (glutamine-hydrolyzing) [Amino acid transport and metabolism]
Asparagine synthetase B (glutamine-hydrolyzing) is part of the Pathway/BioSystem: Asparagine biosynthesis
Statistics
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PSSM-Id: 440136
Aligned: 639 rows
Threshold Bit Score: 208.152
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_015775424   1 MCGIA----------GFCSSGk--HEVRYIKA-MTEVIRHRGPDDEG-AVV-----FEemgssplvckgddtptsaelsv 61 
WP_066843971   1 MGALLiaaaadlgdgGWCSQDggaSRDRIa---NSLGLGLGGPVGSAi-------aPG---------------------- 48 
WP_012792506   1 MSAIY----------GIIHKNgdpVSQETAHT-MATAMRHRAIDGEG-SWH-----EG---------------------- 41 
WP_012875097   1 MSGIV----------GVISFTd-pVPSDLVKRiVASGMHRCGSAAAKh--------LG---------------------- 39 
WP_108383459  21 VSGFV----------AIARLDgtpVDVDAVER-AVSVITHRGPDGRR-SLV-----DG---------------------- 61 
WP_126535374   1 MSDFA----------GLWRLDgrpVDDHDVSR-LARGLEARGIG-PArVWR-----EG---------------------- 41 
YP_425943      1 MAAFC----------GVVRMDdepADADEAAS-MAGAF-AAAPGGRPtLRR-----DR---------------------- 41 
WP_014748460   1 MSFFA----------GLVGTEpvpAEGSDGLD-GIAATYGG--GGRAsVWR-----GD---------------------- 40 
WP_060685144   1 MSAIHaiw----drqGVLt-------AEVIER-MLQAAEGYGNS-AGr-WEvihmpEG---------------------- 44 
WP_108880571   1 MSGIG----------AIFWKDgrpAERAVIER-LGQGLRPYGRTAQT-VRT-----SG---------------------- 41 
WP_015775424  62 ipyspkflidsviqrgvKVALGHRRLSILDLSSLGHQP----MCTQDGRYWIVFNGEVYNYIELRAELEKLGHTFISRTD 137
WP_066843971  49 -----------------ALLFARPPLRDAPPARLGARPrpwsAHVGPDGARVLFAGELQDREALLARLPA---APAGKGD 108
WP_012792506  42 -----------------HVVLGQCMLTFKAADKTQRIP----LV--TDDLVIVADIRIDNSPYIRKLTN----SPKDATD 94 
WP_012875097  40 -----------------QVAVGCAELKITCEDFEDDQP----LSFNGGRSWVVMDGRLDNRDELFDLLAVRS-QQSSISD 97 
WP_108383459  62 -----------------SVALAHLQHRTTPWp--TGFP----LQ--DGRVLVTGAARIDNRAALRDRL---GPFDDPVSD 113
WP_126535374  42 -----------------SFALVHRQHVFTPEDERERLP----LAGPSGGV-LVADVRLDFRSELAAALGF-ADEEAARPD 98 
YP_425943     42 -----------------AGAFAAVSLPLTPEDRFDRQP----WTGRDGRITLLFDGRLDDRAGLIDRLGLDGKRAEGMAD 100
WP_014748460  41 -----------------SAAMVHVPRPVTPEDRLDRFP----AAFAGGTSRLVFDGRLDNREDVIRALALDPARAVRLGD 99 
WP_060685144  45 -----------------QIFLGVNNLLLDDKDIRSLQP----VSTKERTRYAAMDGQLFNYHDIKNQLVSEGAVFGSMSV 103
WP_108880571  42 -----------------SCGVVFALRGTTGMDDKASQP----LQANDGRHLFVFDGRLANRAEIARDLGGSSFRSDRVSD 100
WP_015775424 138 TEVILASYAQWGEECLSRFNGMWAFCIYDSQARTLFLARDRFGVKPFYYWTSpTGLFAFASEIKQFTVLPGWRAMLNSQG 217
WP_066843971 109 DALYAAALAHLGSECDRFINGHYAAIAWYPEQRRLRLVRAPLDAPPLHYWQD-GKRIVAASTPRAAI-AAGADPAVDEEH 186
WP_012792506  95 IELLLAAFRTWGQHCVYYLNGEFAFCIWEREHNRLFLATDRVGFKSLYYYDT-PDVFIFCTEQKGLLAAKPLPHYFNEES 173
WP_012875097  98 CRLAAMVYQRWGEHCVSKLVGNFALIIWDDRAKSMFCAVDHLATRPLFYTLN-TKRFVVASTIKQILQVPGISDEIDDTY 176
WP_108383459 114 AALVLAAYRQWGRACPVHLVGAYAVAIVDRAADRVFLARDHAGLRPAFLART-ADRVAVASDIEPLLALEWVTTAVDDGV 192
WP_126535374  99 GALVLGALERWGEAGVSRLYGDFALAFWQPGERRLVLARDPLRDRSLFVHRG-AALIAFATRMRPLLALPDIPRDIDENA 177
YP_425943    101 GALVAAAYERWGTAILAGLAGFWVLAVWDAAARRLVLARDPMGGRSLFYHRQ-GPVITFAASTLALLRLPRVERVLDETV 179
WP_014748460 100 GALVMAALERWGIDACPRLIGAFAFAWWNESLRRLVMAADASGGRTIFAHSD-GRRLRFASRPLAVLAFPGMARQVDETA 178
WP_060685144 104 AEVWMKWEEKTENSQYSEINGDFAGFYVDKSvNKLKIVDNSYSSKQIFNYQS-ENFWVFSTSLYSIIASGLTDkALDQVE 182
WP_108880571 101 ADLAFQSWLMGGDAAVKKWSGEFSFICWDAHEETLLACRDHIGLRALCYHET-PQRVVVASAPRAVLSLPDVERAIDEQK 179
WP_015775424 218 AYDFLVFGITd--HTEETMFAGVYQLRPGYCVTLS-VDnvnglspGksLPA---RA---WYDLR--PRpfAGRFDCAVRE 286
WP_066843971 187 LADALFLNFr---DARRGWFCGIHRVAAGEVVEIG-PG-------G--VTR---RQ---YWKVEdmPAvrFARDSDYVDA 247
WP_012792506 174 LITYHFrd----gDPVATHTKYVYALLGGYGLTLE-DR-------C--IRQ---VR---YWNPSp-GKysFDDGEECAWE 232
WP_012875097 177 ILANLCLQSTlphHTSLTPYTSIRRLLPGHAIVTDiNG-------R--QRI---TR---YWRPEelPVlySSPRSEVIER 241
WP_108383459 193 VVEGLVGAAs---SAARTIYADVDRLPAGTSATVT-TD-------G--IER---RR---HWRPEaiDPldLPSDRAYEVG 253
WP_126535374 178 VADRLILNTa---DPEQTLYPAIRRVPQGHVFTVT-AE-------H--TAK---RR---WWTMPqpGGlrFPGHEATVAA 238
YP_425943    180 LGDLLMLTMg---ERDRTFYRDISRVPSAHLVVCT-PE-------G--TVI---DP---FWHPPvgGElrLPRDEDYVEA 240
WP_014748460 179 MAHLLLARPi---PAGATPFRGVFRLPPAGLLVWK-DG-------H--HSI---SR---YWRPDpgRRivYRDPRDYVEA 239
WP_060685144 183 VAKLLSQGYV---SEGATIYKNVKNLTWGTQLQLS-CGk-----dGwlFSTnvcKSvdnYFSAQ---------TETDAEG 244
WP_108880571 180 IADQLVQLFh---DGERTYYKDIRRVLPGHLFRVS-PA-------K--TES---TR---YWSLDevPDvrYARDEDYVEA 240
WP_015775424 287 FRDLFEQSIALRLRADAPIGSCLSGGLDSSSIVCVLNDLlrkqgvQaLQKTFSA----CS------DVDR-FDERKWIDL 355
WP_066843971 248 VEHAMRNALRETAAEFDRPAVQLSGGLDSQAVASFAMKVlpk---dtpLKAYCWvpqdGYqal-pwPGAh-GDETAHASA 322
WP_012792506 233 MRKLLTTVVKNRISTDRPIGITLSGGLDSSSIACLLAKElaa--vnkPLYAFSSvlpeTAq---------gKDERAYIER 301
WP_012875097 242 VRATFKEAVRSQFRSCAAVMPTFSGGLDSSSIVCMAVLLqre--sglPCKGFRPvse-------tyKTGtvADESSFRRA 312
WP_108383459 254 FRELFDRAVADRCRGP-AVGSLLSGGLDSSAVTCAAAGHr------sQIPTYSL----GF------DATpvSDEREYARA 316
WP_126535374 239 AEAVIDRALASGVRAVGPVGTCLTGGMDSATVTLFARRHlp----peRLIALTRvpggp--tapddASHy-HDESPRAGA 311
YP_425943    241 ARELLERAVRANLRSLRPVAVLGSGGLDSAGVAATAARLla----prPLPLYCRvpptDWsgp-elSTSy-PDERPKLAA 314
WP_014748460 240 ARELLDQVVAANLRAIDPVACQLSGGLDSSAVAATAARLss----prVLHTLTAqpdpSApmpaerPRGf-YDEGPFAAA 314
WP_060685144 245 LKEALIDTLFMETSGDKNIGLLFTGGQMSTTLAALGREAg-----IrPALAYGL----AV------DPSE-VDQRYADYK 308
WP_108880571 241 GLELFNEAVRSQVAGEPRVGTFLSGGLDSSSVAVTALDHlsd---nqALPAFTWvpsrDWdg--rcRDGsyGDETPFIED 315
WP_015775424 356 VVGKT-RVDAHYVYPAP----DSLF-EESPAITWHQDE---PFG-STSIYAQWNVFRLAAQNgVKVILDGQGADEQLCGY 425
WP_066843971 323 FAAMHpAVDLELVDTGD----LPLD-HQEETFFLLAGLa--PMg-AGNMHWGHEILRRAAAAgHGVVLDGHYGNNGFSYD 394
WP_012792506 302 ILQHCpNIIPTFVDAAA----FGPF-DDISDAFNHDETfpnPF-----FYMDHAILRAAKEKgVGVLFTGYGGDHWVSWQ 371
WP_012875097 313 AIKMy-GLDVIEFPGDD----LWYMrDLVEGTFPEPDE---PFGaYLVRAEMQVYADVAWRSgCNVLVFGYGGDELMQGT 384
WP_108383459 317 VVDHV-GARSTVVDGDA----PGPF-ADAEAMLSAVGR---PI--RGNTTYLHWRLYRAAAAdVDVVLGGFGGDAVVSHG 385
WP_126535374 312 FAAGQpGLNWHAVGDDG----LDWGeADRRRWFLETGV---VADnRINGAWFLPLARFMAARgGRVILTGGGGNFFYSYD 384
YP_425943    315 LAALHpNLRVMSVEQAG----PHRFdEDQTCLFQRYGL---AARaADNIGWLLGAVDQARAAgHRVLLTGDYGNTTLSAP 387
WP_014748460 315 TAALYpNITPHYLPAGA----ITPGeEDATALFRQFGV---PMRnFTNFGAWQPLYARAKALgASVILTGTAGNCTLSWK 387
WP_060685144 309 FAEDT-SYEEGLALYQDllteKSL--EHWEDYISQMEv---PCL-RMSGFIHYLLAQFIDGRs-EVVLSAEGGNTLLGAD 380
WP_108880571 316 ICNLHpRIKPHFVRSEG----HGLF-HQLDDFLDYSGV---APRnAINLCWIHDINMAARDQgLNVLLDGGMGNMSLSWS 387
WP_015775424 426 ------HGFFGPR-LVtlfrnsqfnillqdlvgmhrlhgysiadsl-----kfmlpyvlsdsctqllrriggythcrpew 493
WP_066843971 395 g----lTGPAT---WLrqgrpgrawrevrrrggkgsdarrflsqa------vmphlpirlrrklrgmrgraldpfdswcp 461
WP_012792506 372 g----hTVIYN---MLtagryqlvyqlimefaeqeqrhpfqiv-----------krelaaqtsiyralrgrrrkslngta 433
WP_012875097 385 s-----YFLGD---YLrqlkikelihgiwsesrwpnlnvttlllryailpmvpplfwrfsinirghnrrwnpetewyipg 456
WP_108383459 386 l-----GRLTD---LArrghwlglarelrarahhrgespwrrlytd-----avrplvprsarrlarrlrdgdpierlspv 452
WP_126535374 385 g----gLVELA---LLrqgrigallrllagrarnyrpgllalvk--------srmlapceprrmrawrkgwdapwshlsa 449
YP_425943    388 g----rGAPMA---LLrqgrlmalarelagwrrqrgwswpkvar--------etllyripglsplrslgrnpgswrswtl 452
WP_014748460 388 s----eALLAD---LAaagrfvelarqlhglrrhghrpwpqir------------qnllryvvpararrqmqrlrgtgea 448
WP_060685144 381 natfgfGLYLEKYdLLkswipmikklegvlpsksflpvkk-----------------hldlihllgrhidespsitaqnl 443
WP_108880571 388 g----eGVLLE---RWqngdyanllrdvfagpggakgvyrrlthmll---friapdwvhrryaqlrgdrgslplwrrrsv 457
WP_015775424 494 LNYGHLqae--avDPFQKLgAR------------E--GNI--------A----EHSRA-QLLSSNLQMLLHWEDRDSMAH 544
WP_066843971 462 MRRDYAer-----agVLER-SAsa-----------ghDPlfldlassrEw---RAATL-AGGQG--DGADTR-LALELLH 517
WP_012792506 434 LRKGFIrk---yrQMIDLRpvt-----------------------dvfEt---MMDNV-MSGRV--GQLPAMLSNRNEAY 481
WP_012875097 457 IPPWLSvqqciksgIFARV-WKefpehy--------------tplpsrAq---HLVWL-RQNNF--SLWLD--NYVFMPK 513
WP_108383459 453 IDRDRAra-----vaWPDR-LRqaq---------vtpSPLa-------ThrerQVAGL-ARPNW--QFDLEAANALGAAA 507
WP_126535374 450 LNPTFAve-----tkLLDR-LDlsryrsrsgpprPsah-------------atRLWF---HGDE--TIGDWS-VAYRALT 504
YP_425943    453 TRPEAVra-----lgLEAR-ARaagapgfpmpttTpa--------------asRALIL-ERYGR--LRGDLA-AQTTAVD 508
WP_014748460 449 wRKRALlt-----adLEAL-VEpvavtdsvlistDraDydr----------rsRIAYL-DRYFA--NCQWLA-GHPY-VT 507
WP_060685144 444 FSl-----------------YGes---------aEg-D-Mg-------Sd--yKALREwQFKQDLPGRLYVESSQFYRQN 486
WP_108880571 458 INPDFAre-----mhVEDR-MAhygwdffstpvrDt-----------rRv---RGELF-TGSFS--HERADIHQALRAMY 514
WP_015775424 545 SIESRVPFLDYRLVEFVLGLPDEFKV---AGGm--TKLVLRESMREVLPEEIRTRVdKLGFVTPE-EVW-V---R-EI-M 612
WP_066843971 518 GVPMRSPLAYRPLFELTAGIPDEQYL---RDGe--TRWLARRLLKGRVPEQVRTER-RLGIQSSDwP-VrWgreR--EaI 588
WP_012792506 482 GIISAVPLLDRTVLEYMMDVPDQMFV---YNGh--KRSLIRHAMEGIVPDEVLWRK-DKGKYSPDfmarslagisradai 555
WP_012875097 514 GCEARMPFMDRRFVELALMIPTEWKRgfdADGtivTKLILREAMRSILPEAIRERR-DKVNFGRTlAlg----lR--HeL 586
WP_108383459 508 GVEPRFPFFDRRLMAFCIGMPADQSL---RDGv--SRSILRRAVE--LPERVRDRH-HKSSLAPAyR-RaLvdeR----- 573
WP_126535374 505 GIEWRAPLAGREVIEFFAALPQEAFV---RDGr--GRAIARSILAGHRPEEIVRDR-RSGRQLGDwF-AiLtaeR--PrM 575
YP_425943    509 GFELRSPLAYLPLVEFTLRVPSPQFC---RDGr--LRWLARRTLADRLPPEILMED-RLGAQHPEwF-DtLsslR--EsY 579
WP_014748460 508 GCDPRDPLGDRRLVEFCLALPVTIWQ---TNGk--PRSFAREVLKDRLPPRVVDNQ-KRGYQNGDwF-HrLtqlR--PaF 578
WP_060685144 487 GIEVRYPFLNELVLEEGLKSAGHFN------Se--QNATVKQWLKNWAKDKVAARP-HYESRLPL-ANY-L---KsG--K 550
WP_108880571 515 NVETRDPFSDRRLIEWSLGLPEAQSR---RFGq--NRWMIRRMMQDKLPASVLDNP-GGGEQVIDwH-ArLtwdL--PrL 585
WP_015775424 613 PDMFQSKIEQ-TLAVAG-KCFNHESVRSEFAK-----IRCg-----Kkn----fSFWPWRVVNFGEWVQ------RF 667
WP_066843971 589 MAELERL--S-RDpAVA-DMLDLPRLQRWMRE-----WSGen--svGglesariFCAAgRGLTAARYLRfqargng- 653
WP_012792506 556 tqspeyalafekylskpamshlaagtelstirliqgiicskvisilqkngylfegnfs------------------- 613
WP_012875097 587 PKLLNNR--S-WEvVER-GYVEQDGLERALKS-----WRIgmrdf---------lpqicSLLATELWLRqmrtrshe 645
WP_108383459 574 -EQIRQLy-DtTp-DALwRYLDRDACLGALDRaaegpFPAlt---aRv-----yRPGMl-----aAWSHhrpdapKH 634
WP_126535374 576 LAALERL--K-ASrSAG-RVVDLARLERLLND-----WPAda--aaAearrgeyHFVLtRGLETAEFLAwhdrsnt- 640
YP_425943    580 QADLPRL--A-KSpLVA-TLLDLERAGHLLDS-----WPDia--rdAaprhhdhALALvRGLHVARFVRwneggnd- 644
WP_014748460 579 MAELDRL--E-ASaSVR-RMVNLQRIRAVAEN-----WPAda--daAmardaemLDLFaRGIHYSRFIRwvegsna- 643
WP_060685144 551 ADIIKHQLQK-EDALVY-QYLDFKEIQGMLKA-----AEKg-----Kaq----fEDQLWAAAVMGAWLEf-----HF 606
WP_108880571 586 REELEAL--S-DDpDTA-RFIDVKLIQAYLDD-----WPAetpfgsKdrgyafiPVGIcSAIAAGRLVRrtkgsnr- 652
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