Conserved Protein Domain Family
sigpep_I_arch
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TIGR02228: sigpep_I_arch 
signal peptidase I, archaeal type
This model represents signal peptidase I from most archaea, a subunit of the eukaryotic endoplasmic reticulum signal peptidase I complex, and an apparent signal peptidase I from a small number of bacteria. It is related to but does not overlap in hits with TIGR02227, the bacterial and mitochondrial signal peptidase I.
Links
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Statistics
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PSSM-Id: 131283
Aligned: 8 rows
Threshold Bit Score: 105.599
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
jcvi:BA_1287   6 KVISNVISFVLFALMVCLAFVVISSKASGGDPTVMgyqfksVLSGSMEPTFLTGSIIAIEPtKDGSKYQKGDVITFKEKD 85  Bacillus anthra...
P54506         2 KLISNILYVIIFTLIIVLTLVVISTRSSGGEPAVFgytlksVLSGSMEPEFNTGSLILVKEiTDVKELQKGDVITFMQDA 81  Bacillus subtil...
BAC13257       8 RKVGKFIFTCSWIVLITFLAIALVSKANGDDGSILgyqvksVLSGSMEPGIQTGSIIVIDTkANPADYQRGDIVTFTGEE 87  Oceanobacillus ...
BAB82001       4 KKIVNTIYYIVISMLVIILVNNFMSKSD-SIFKAVgfrtysILSGSMEPEINTGDLAIVKS-IDADDVKVGDIITFKYEG 81  Clostridium per...
AAM02244      20 GWKAAVFYVVLGVALGYGLRYGLGFVLGTPDPVVT------VISESMYPYYNVGDVLLVVG-VPYRDIKVGDVIVYRLPG 92  Methanopyrus ka...
AAL62667       3 GWVKDLIWFAG--IVAALLAYSLATGVAWPIAVVS--------SYSMEPTMRVGDFVFLTG-ATCTSIQPGEVVVYVARN 71  Pyrobaculum aer...
BAB66250       1 MKKSDILLLIVIILIYIVVLSGIVQTAS-------------VEGVSMYPIFQNGFLTFYTS---PNNIKIGNIIIYKSPT 64  Sulfolobus toko...
WP_010884691   3 EKGKEVISTLLIILLTLALYFGLRVALHTETPLVV------VVSGSMEPVFHRGDVVLLEG-VRPEEVRVGDVIVYRSII 75  Pyrococcus hori...

jcvi:BA_1287  86 E----KIITHRIIGVK----DTNGKVMYETKGDNNNGPD---LEPVLAENVIGKYADITVPYAGYALNYANSKAGAALLL 154 Bacillus anthra...
P54506        82 N----TAVTHRIVDIT----KQGDHLLFKTKGDNNAAAD---SAPVSDENVRAQYTGFQLPYAGYMLHFASQPIGTAVLL 150 Bacillus subtil...
BAC13257      88 G----MLITHRIQEVQ----NSG--TQFITKGDANNGPD---VSPIPVSNIVGEYSGITIPFVGYVLHFATTAQGAALLF 154 Oceanobacillus ...
BAB82001      82 -----KVVTHRVVEKN----EEG----FITKGDNNNAND---TEIVRGEDLIGKVL-FHMPFLGYVTVFLSKPIVISGLM 144 Clostridium per...
AAM02244      93 Kp---IPVVHRVI--------AKTPEGVITKGDNNPLPD---P-WCP---------------------IRPKEISGRVVL 136 Methanopyrus ka...
AAL62667      72 PmwygNWIIHRVYQKQ----NSGGQCGLVTWGDNNPFPDqrvGEPLVSNNVVGKVLFTVPYIGVFPLVVRPQGIGDIAIA 147 Pyrobaculum aer...
BAB66250      65 Fn---TYVIHHVIKIN----YIDGEKFYVTKGVDNITNP-------QSDNKIGLEPPQGIP---QSQVIGKVAEVNGIVI 127 Sulfolobus toko...
WP_010884691  76 Sr---YPIIHRVRGIKyiyiNGKRELCFITWGDHNPVPD---IYYTPE-------G--------ILDCVPAEAVEAKALA 134 Pyrococcus hori...

jcvi:BA_1287 155 IIPGVFLLGYSAITI 169 Bacillus anthracis str. Ames
P54506       151 IVPGVMLLVYAFVTI 165 Bacillus subtilis subsp. subtilis str. 168
BAC13257     155 ILPGILLVSYSIITI 169 Oceanobacillus iheyensis HTE831
BAB82001     145 VLIAISILWDTFKVD 159 Clostridium perfringens str. 13
AAM02244     137 RIPYVGYPKALLDRY 151 Methanopyrus kandleri AV19
AAL62667     148 AWLGRLFIFGAVTYA 162 Pyrobaculum aerophilum str. IM2
BAB66250     128 SIPYLGYISILFSLL 142 Sulfolobus tokodaii str. 7
WP_010884691 135 VFPRIGIISIKVREL 149 Pyrococcus horikoshii
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