Conserved Protein Domain Family
PRK05731

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PRK05731: PRK05731 
thiamine monophosphate kinase; Provisional
Statistics
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PSSM-Id: 235583
Aligned: 303 rows
Threshold Bit Score: 252.06
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
298490181  12 DIGEQGILERLQRFCPpe---iiGDDAAVLAitaqeSLVVTTDMLVDGVHFSDITTSPEDTGWRASAANLSDLAAMGAFP 88 
14520605    4 SMREGEIISLFMKHFErh---slGDDAGFIkln-nsWLLVTSDMLVWKTDV-PDFMTPEDAGRKVVTMNVSDIAAMGGRP 78 
18978249    1 -MKETEIIKLFQEELKsk---vlGDDAGFIklg-drWLLLTNDMLVWRTDV-PDFMTPEEAGAKVVTMNVSDIAAMGGKP 74 
57640825    1 -MRESEIIELFLKHLKrhgelplGDDAGALkig-deWLVATNDMLVRKTDV-PDIMTPEQVGFKAVTMNVSDVAAMGAEP 77 
212223565   1 --MEREIIELFMKYLKkqgdlplGDDAGAlri--gdEWLVATNDMLVGKTDVPDIMTPEQVGFKAVTMNVSDIAAMGARP 76 
242398574   1 --MEREIIELFMRHLKlqgdlplGDDAGAIkwk-neWLVVTNDMLVRTTDV-PDIMTPEQVGFKVFTMNVSDVAAMGATP 76 
240102493   1 -MMESEIIELFIRHLKrqgdlplGDDAGA-LrlgdrWLVATNDMLVRKTDV-PDIMTPEQVGFKAVTMNVSDMASMGAEP 77 
13541833    1 ---------------------------------------------MIGKFF--------------ASINLSDVAAMAGIP 21 
16081636    1 ---------------------------------------------------MPDGTDPHLAGRFMASINLSDIAAMAGHP 29 
288932586   2 EREIIDIAKRIFKFEEe-------DAGFFkfg--daYIVIANDMLSRSFDF-PSKLLPKQIGWKAVTASVSDLAAMGAKP 71 
298490181  89 LGITVGLGLPGDLAVSWVERLYQGMTECLQKYNVPILGGDIVRSPITTLAITAFGQANpNFI-IRRSTAQVGDAIIVTGI 167
14520605   79 MAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTNEADD---IIIDGGSLGiGKRlLLRSNAKPGDLVCVTGD 155
18978249   75 IGFFFSLGLPRDINEKTLREIAKGIKRGTKRYNVEVLSGDTNESNELVIDGGAIGEAErI---LLRSGAKPGEVVCVTGD 151
57640825   78 IGFLFSLGLPEGLDEDYIEGIARGIGEALDYYKIPVLSADTNEADDLIIDGIALGKTKrL---LTRSGAKPGDLVCVTGD 154
212223565  77 IGFLFSLGVPRGFDGLYLEGVAKGIGNALEFYEIPVLSADTNEADDLIIDGIALGRTRhL---LTRSGAKPGDLVCITGD 153
242398574  77 IGFLFSIGVPRDFERDYLEGISRGIARASEFYRTPIISADTNEACDLIIDGIAVGKTKrL---LTRSGAKIGDLVCVTGD 153
240102493  78 LGFLFSLGIPGDLDSDYLEGIARGIGEALDFYGLPVLSADTNEADDLIIDGAALGITErL---LTRSGAKPGELVCVTGD 154
13541833   22 ISFMTAYSISPEIEISFLEDIESGIMKVLKMYDVDFIGGDLKEGMDLILTGIAIGKQKkTLT-RKRSDIGRKQMVAYTNK 100
16081636   30 ISFMTAYSVSPDLDMEYLEAIEEGMMSVLRKYSVDFIGGDLKEGDDLTLVGIAIGRQTkKLT-RKRSDIAKGQMVGYTNR 108
288932586  72 IYFSYSLGLS-REEISFVEDLMKGIREALDFYGMKFLSGDTNESTELVLDSVAVGIARnL---LLRSNAKVGDAVCVTGD 147
298490181 168 HGASRAGLELLLNPQI-CQNleseekaaliKAHQRPNPRLDVIPILQEIftspcpiSISGMDSSDGLADAVLQICRASRV 246
14520605  156 LGRPLTALLLWMRGEKiPREi--------eEKARNPRARVEEGVKLSSL-------ANSAIDISDGLSKELWEIANASNV 220
18978249  152 LGRPLTALLLWLKGEKiPREi--------aEKMKNPIARVREGLELANY-------ASSAIDISDGLSKELWEISKASKV 216
57640825  155 IGRAFAGYLVWKYGLEvSEStrk----alyEKFLEPIARVKEGIILSKS-------ANSAIDISDGLSKELHLISKMSGV 223
212223565 154 IGRPLAGLLVWKNDLDvSLStke----ilyEKLLEPRARVKEGIKIGNY-------ANAAIDISDGLAKELHLVAEMSGV 222
242398574 154 IGRALAGLKVYFRNLKiGERtrk----vlyEKLLEPKARIKEGQVLSKY-------ANAAIDISDGMSKELHLIAEMSKV 222
240102493 155 LGRALAGYLVWKNGLEvSDAvrk----plyEKFLEPRARVREGSELSKV-------ASSAIDISDGLAKELYLLAEMSQV 223
13541833  101 LGRAASGYIFYKSGYDsVEGi---------NMMLGITPRLEEARIISEYg------AKFMMDLSDGLYSSLNQMKADYGV 165
16081636  109 IGRAASGYIFYKSGYDrKRGl---------SMLLGVEPRISEAIKMSEYg------ARFMMDLSDGLYASLDQMKQDYGV 173
288932586 148 LGRAYCSLLYLLEKVEeIEEki-------lEKFLKPVARVDEGLKLANI-------ANSAIDVSDGLSKELNLLANSSGV 213
298490181 247 GAILeQSKIPlpsafhkwltpgqwlhppqawlNYALYGGEDFELVLCLPPPAALTL---VQKLGAGASIIGTitpgltvi 323
14520605  221 RIIIeEERLPisdsvke---------ivsdpvKVALASGEEFELLFTIPREKVEELd-------iDFKIIGRveggng-- 282
18978249  217 KIVIdPNSLPvhekvke---------ivknpvEVALASGEEFELVFTISQEYLDILsfeFS-------IIGRvekgegv- 279
57640825  224 GIEIsSGKLPirgevyeva-----evigkspvELALASGEEFELLFTVPPEKISELe-------vDFTVIGQvregn--- 288
212223565 223 RIEVdASKLPimeevfeva-----ellrrdplEIALASGEEFELVFTIPPKYTEEL-------SFDFTVIGTvhkgagvf 290
242398574 223 KIIInAEKLPireevfeva-----ellgldpiEVALASGEEFELIFTIPEEHLDQLdfdFA-------VIGRvekgegvy 290
240102493 224 GIEVrPESLPlgkgveeva-----ellgldpfEIALASGEEFELVFTVAPEFVESLn-------fDFSVIGRvtrgkg-- 289
13541833  166 GFKIvEDEVVyddsarkaa-----eisgasvyDIACGYGGDYELLFTVPEENYRDFaqaMESNNIEVHFIGEtwege--- 237
16081636  174 GFRIvRDEIAyddsvnkas-----eisgsdvyDIAGNYGGDYEILFSVDEANYKDFqaaMDSEHIEVHFIGEtwngdn-- 246
288932586 214 MIKVfEDRIPireevlefc-----tsnnlnpiEVALNSGEEYELLFTVSKDKLEDLd-------fEFSIIGEvskge--- 278
298490181 324 lhheneriPDQAL-SLSQ-GFQHF 345
14520605  283 --vyikrgRKIEE-LEVL-GWEHL 302
18978249  280 --ytttgeKVPMR------GWEHF 295
57640825  289 ---gvymgRKPLFp----lGWEHF 305
212223565 291 itteekrmEVPPI------GWEHL 308
242398574 291 lrrngkleKMPVL------GWEHL 308
240102493 290 --iylvddSGKRV-MPKL-GWEHL 309
13541833  238 ---nivfdGKTWTkMKDE-GYEHF 257
16081636  247 ---imfdgNAWHP-IIGR-GYEHF 265
288932586 279 ---gvflvGKEKK-PLLPaGWEHF 298
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