Conserved Protein Domain Family
Trypco1

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pfam19493: Trypco1 
Trypsin-co-occurring domain 1
Trypsin-like peptidase effector in the classical NTP-dependent ternary system (vWA-MoxR-VMAP) frequently co-occurs with one of two proteins (Trypco1 or Trypco2) which are mostly mutually exclusively. This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000703) is described by MIBiG as an example of the following biosynthetic class, saccharide, in particular the kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus.
Statistics
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PSSM-Id: 466108
Aligned: 273 rows
Threshold Bit Score: 41.0677
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:GEI7407_1338          7 IR-L--EDG---TVI-YM-EtTeniqAPAvktpssqgasevpreltradygagdkgwgrasvapVANGDrppQ------- 71 
WP_048867735              5 ITtIlgADG---EEI-YI-QyD----EQDsdel---------------------------qavgYIDDI----------- 37  Scyt...
ESQ11646                  7 LE-L--PNG---VVV-YMnA-V----DDPvesatspqppg-------------spvshrqsadgAEGIEdrlI------- 54 
KKJ00562                  8 IT----DES---GNVqPI-TiV----ENDedlatvpaa------------------elgddresYGLLE----------- 46 
OUC14679                  6 LI-L--EDTdatYDV-LV-E-At---QPIqpnqp-------------------------lddleSYDPN---Akrsltip 48 
ERN41367                 10 FV-YtdDHG---NQYeIFvEaR----DVGlpeask-----------------------dllgdqHDGRG---D------- 48 
EGW54316                  7 IR-L--ADG---RLI-MV-E-M----EQGdlalp-------------------------gsgaaPTDLP---Aga----- 40 
KQU75925                 13 LS-VevDA----TDV-IV--------TPPpagl---------------------------vergGLVER----------- 40 
PRJNA354524:THSYN_09425   8 IN------G---QTI-LV-E-V----ADLkveg---------------------------qsadNRREP----------- 33 
KQR54061                 10 IG----DD----VKI-AVaA------EQRg---------------------------------pQLVAD----------- 30 
jgi:GEI7407_1338         72 ----EAALQNFQA-IEHTIRTYtAYTLNAF----RQ-VAvaN----IDKVTMEFGLKVGGEMGvP---YITKGTAESNIK 134
WP_048867735             38 ----KERTERLTKmTVSTVRSYsKLVLDSV----KE-GI--ThtttPTKVTLEFGLQAGGETGvP---FVTKGTAQANVK 103 Scyt...
ESQ11646                 55 ----DAATAKAEA-LTGVIKGIaQMIPTAF----EH-AGga----eVEKVTLSFSIKAGGKAGiP---LVTEGSAEGSIG 117
KKJ00562                 47 ----DRAIAKLKD-IHSTIQAYsRYAIGAF----QN-LPga----eVEEVTLKFGITIEGSTGlP---LLTGGSAGANFE 109
OUC14679                 49 ttlpPEVRVKLAD-VHRTIQGYtQYAIGAF----KNlAI--Adv---eEVNLKFNIKISAEGGi---pVIASGKTESDFS 115
ERN41367                 49 ----DIPEVKMQR-ATDMIRGYtTYAVSAF----KE-FSaa----rVEEITLKFGLKIGGKVGiP---YITEGSAESNLE 111
EGW54316                 41 --eaTGLSDNISS-AIGLLRNQiSAVADTV----QE-ALv-Sn--rPDELKVELTIGFKGESQpi--pVILTGATSGGLK 107
KQU75925                 41 ----GVVADKVRD-IGQEMRSLlSAVTRPV----RE-ALea---tqPDSWSVELNLGFKGEAGiP---CLTKGEANGSIK 104
PRJNA354524:THSYN_09425  34 ----TAASAESGD-MTDRIDQLlKALTTPVqaacQA-AG-------AAEWSLRINIGFGGKAAlP---FIASGEANAAVR 97 
KQR54061                 31 ----KDITARLSS-VTDSIEVVaKAALDAV----KK-AL-------PDKATVELSFGLAIEEG-KllaLLGKGKAEASIT 92 
jgi:GEI7407_1338        135 ITVECSF 141
WP_048867735            104 VTIEWDF 110 Scytonema tolypothrichoides
ESQ11646                118 VVLECRY 124
KKJ00562                110 IEVKCKP 116
OUC14679                116 IEVKCKF 122
ERN41367                112 IQVKCTF 118
EGW54316                108 ITASWKR 114
KQU75925                105 VSASWKK 111
PRJNA354524:THSYN_09425  98 VTAKWKP 104
KQR54061                 93 VTLEWSR 99 
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