Conserved Protein Domain Family
COG2374

?
COG2374: COG2374 
Predicted extracellular nuclease [General function prediction only]
Statistics
?
PSSM-Id: 441941
Aligned: 441 rows
Threshold Bit Score: 79.2947
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_045111709  527 IEIKIATQNVLNFFNs-------pFGgeenkhgenrgadSQSEYTKQKAKIVAAVRGLDADIIGLMEIENNSfn----df 595 
NP_603788      25 DEAYIASFNILRLg-------------------------aAK---KDMPQTAKILQGF--DIVGLVEVINRDg------- 67  
WP_011921592  734 DTFDVVTYNMEFFgapt-------------------sayGPADKALQMQNAVKVINKLDADVYVVQEISSd--------- 785 
WP_015425020   42 NTLDVITWNLRNF---------------------------PEg--TDLTTLKEMISALNAEVIAFQEIMDy--------- 83  
WP_041557793 1396 KTFDVVAWNIEWFgdetn----------------sptvgNPLSDAIQKDSVLTILKKMDADVYAVEEISDd--------- 1450
WP_013752234  960 DSFDVVAWNIEWFgdenn----------------appagRPMSDEIQRDSVRTVLRRLDADVIAVEEIADd--------- 1014
WP_084694874  756 TTLDVMTWNMEFFgatq-------------------pdfGPNNEELQLQNAARLLDSVRADIIAVQEVSDe--------- 807 
WP_058884881  737 KTLDIVTWNIEWFgdekk----------------spaagNQNSDEIQKEKVKQILLNLDADIIAVQEIIDi--------- 791 
WP_075095638   26 DYLKIGAWNIENLgg-----------------------rvPN---QHPAAIAEHLLVADVDILALEEIWDTDgvpetmts 79  
WP_103426873   34 RVLLIATWNVRAFGGltekwvaaeDD-------------SPKRDLQSLHTIAAIVRRF--DVVALQEVKGNL-------- 90  
WP_045111709  596 SAIKDLvdsvnEYYTqdrpskehysdsiskrYAFVgfdSN-GDlvldk----edsigSDAITSGMLYRpksVSLKD---V 667 
NP_603788      68 --VEELvdelnKASDe--------------kWDYHi-----SPfgv--------gssKYKEYFAYVYKkdkVKFIKs--E 116 
WP_011921592  786 AAIDDLitqmnVN-Gk--------------sFNKVv-----STswsyswetnpsdpnYPPQKLVVIYDtktTTLKNt--R 843 
WP_015425020   84 NAFMDLaed-------------------ipyYAACv-ySA-----------------TDTYRLAYLYDtrsVTLNNq--Y 124 
WP_041557793 1451 VLFGQMvse-------------------mngYDYVl-----SEavsyp-----ndatGTQQKVGFIYNtatVSVVAt--K 1499
WP_013752234 1015 ILFAELvdg-------------------legYDYIl-----SDavsn------ptgtPPFQKLGFIYKtatVNLVKt--Q 1062
WP_084694874  808 NQLQQLvdm-------------------lpgYARIc-----SDrysysf--ngpdpsFPAQKLCFIYNtevISVVDd--R 859 
WP_058884881  792 DLFKELiae-------------------lpaYDFIl-----SDavsyp-----nstsGMPQKLGFIYKksvVNLKSs--T 840 
WP_075095638   80 PALDQIfqrvnEGDDa--------------dWTYVl-fANrTD--------------GPERHTGIAWNrkrATMVGepmK 130 
WP_103426873   91 KALRHTlk----lLGp--------------nWGLLl-----TDvtr--------gspGNDERLCFLYDrrtVQPSGlagE 139 
WP_045111709  668 KV--ISMPNQqdkpvvnd---ygevvknYKgevlesgKNYQRDSLAVTFTInqTg--K-DLTVAVNHLKSK-GStcaeew 738 
NP_603788     117 GFykn------------------------------gkSSLLREPYGATFQI--En---fDFTFVLVHTIYG--------- 152 
WP_011921592  844 Vm--FKEFYDelragtks--ltnypgtnSNf------fSSGRLPYMVTLETnlNgvkN-EIKFVDLHARAN-SGt----- 906 
WP_015425020  125 Ti--FENDSN----------------------------PFPRPPYILDITw--Nn--S-NYFIINNHFKAY-GDny---- 164 
WP_041557793 1500 Pl--LASIHPyynggdatalsdypdadkTRf------yASGRLPFLMTADVtlGgvtK-QFDIVALHARAN-SSs----- 1564
WP_013752234 1063 Al--LATIHPlynggddsa-lvdypsttDRf------yASGRLPFLMTADVtiNgttE-QIDLIALHARAN-GSt----- 1126
WP_084694874  860 Vi--FEELYDaaragqtdllnnypsgdaSSf------wSSGRLPYMLTVDAtvEgvtE-RIHLINIHAK---SGs----- 922 
WP_058884881  841 Pl--LKAIHPyyngndesalqdfpdpkkSRf------fASGRLPFLMTADItiDnqtK-EVNFIVLHARAN-TSa----- 905 
WP_075095638  131 VpvaFASDA-----------------------------TWNRIPHAVKFSAg-Eg--KtDLVLIPLHMKSN-RVd----- 172 
WP_103426873  140 Lv--VPQEQLdkrd-----------ieeGAl-----rEQFARTPYAVSFRA--Gs--Q-TFILVTLHVLYGeSA------ 190 
WP_045111709  739 dgvdlGt-KTslkfnedkslvkdDDFQGSCENFRVAAAVQLGTEMAKI-------EGDKVLVGDMNSYAQE-HP-MLVLT 808 
NP_603788     153 --------NN----------------E----SQRKAENFKMVDVYDYfqdr-dkkENDIFIAGDFNLYALD-ES-FKPLY 201 
WP_011921592  907 -----DisR---------------------YNMRKYDVEVLKDSLDTHy-----gDSNIILLGDYNDDVKA-S--V---I 949 
WP_015425020  165 ----iDesDS-----------------WDEEMRRRLACQKLDNYISTSl-----sDKKVIVLGDLNDQIAEpED-YNVFL 217 
WP_041557793 1565 -----GpqSR--------------------YDMRKYDVEVLKDTLDAQf-----aDSNLIVLGDYNDDVAF-T--VADEV 1611
WP_013752234 1127 -----QsqNR--------------------YDMRRYDVEVLKDSLDVQf-----sDRKIILLGDYNDDVDE-T--VADEV 1173
WP_084694874  923 -----GfsD---------------------LSRRAYDVQALKDTLDQYy-----pNANLILLGDYNDDVDA-S--I---G 965 
WP_058884881  906 ----aKaqSK--------------------YDMRKYDVETLKKELDANf-----pTKNIVLLGDYNDDVDQ-TV-VANDV 954 
WP_075095638  173 --------DS-------------MPGLPATEQIRRQEAEALVAQLPAIkah--fhDEDIVLLGDTNCLSET-EPaLVAYK 228 
WP_103426873  191 -------------------------------EARTPELRAIAEWLDEwardvnawGHNLIALGDFNIDREG-DErYEAFT 238 
WP_045111709  809 nipagtevkaarntfigkkpqygqdgaiitDSf----GYLN------AV-SI---KD-A-HGW-SYSY-----ND--HIG 864 
NP_603788     202 ------------------------------KHsd--kiTYA--------------IDpAiKT--TIGT-----KG--RAN 226 
WP_011921592  950 a-----------------------------GQpssyqSFVTdtnnykALtLE---ISqA-GAY-SFLS---------SGG 986 
WP_015425020  218 -------------------------------------SFLNkpeeyyFA-DMpiaLSpT---YsNVSY-----PS--SLS 249 
WP_041557793 1612 s-----------------------------STvstfdAYVQdtvnytILtKV---LSeG-DYR-SYVF---------REN 1648
WP_013752234 1174 p-----------------------------TTessfiAYVQdsenynVVtSV---LSdA-GFR-SFVS---------REN 1210
WP_084694874  966 s-----------------------------GEta-yqLFMqae-dydVLsYS---LSaA-GMR-SYIT---------QDN 1000
WP_058884881  955 i-----------------------------GNattydAFVQdasnytIVtSA---LSkA-NFR-SYAS---------REN 991 
WP_075095638  229 ------------------------------EA-----GFTD--------------LNsAn----VVTYd----KGmyR-S 250 
WP_103426873  239 ------------------------------AT-----GLTV---------------PdDlNDvpRTIFtdedeEG----K 264 
WP_045111709  865 SLDHALI------TQSLK-D-RLVDatdw--hinAaes---piYdYNEdr-----kdNkadefyvdDAYRSSDHDSAIIV 926 
NP_603788     227 SYDNFFF------SQKYS-Q-EFTGssga-ldfsGdnpkqmreI--------------------------ISDHIPVFIV 271 
WP_011921592  987 FLDHITI------SNELF-D-QYi---------nEsia---vyDpRNdi-------aNy--------TTTTSDHGPVIAR 1031
WP_015425020  250 HIDHILI------TNELF-E-DFENagsycrtilAen----wmLsWNTy------------------SSTISDHRPVGIR 299 
WP_041557793 1649 MIDHITV------SNELS-A-SYi---------dGsvs---vgYeFyd--------tDy--------TTTVSDHFPVSAR 1692
WP_013752234 1211 MIDHIAI------TDELF-D-NYi---------eSsas---vgYqFyd--------eDy--------AFTASDHFPVSAR 1254
WP_084694874 1001 VIDHITI------SNELF-D-EYl---------pGsea---lvIpFNyi-------tNy--------VNTTSDHLPVVAR 1045
WP_058884881  992 MIDHITI------SNELT-N-NYl---------lGsek---vhYeFyn--------nLy--------EKTTSDHFPVSVR 1035
WP_075095638  251 PFDRILI------PSGQQ-EfR-----------------------YSNqyv---ltpTss----qdHRRKLSDHFLVLTA 293 
WP_103426873  265 FYDQIAWftagegRPALSlDyRTSg-----------------sFdFREvalprrglsNr------sLSWRVSDHYPLWTA 321 
WP_045111709  927 LS-YK-H 931 
NP_603788     272 VE-TS-K 276 
WP_011921592 1032 FN-LK-Q 1036
WP_015425020  300 IS----K 302 
WP_041557793 1693 FI-LE-E 1697
WP_013752234 1255 FI-FD-T 1259
WP_084694874 1046 FE-LT-P 1050
WP_058884881 1036 LQ-LN-D 1040
WP_075095638  294 VRvLQdD 300 
WP_103426873  322 FGl---- 324 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap