221053708 1 MEDLSEVFDIYAICACCKVtppndgiknepfgprtfR-GLGNNGALPWkCNSVDMKYFSSVTTYVDeskyeklkwkrery 79 66356564 7 RTFKMSKKNVSIVVAASVL-----------------SrGIGINGQLPW-SISEDLKFFSKITSNNC-------------- 54 71653378 14 EGTRLALRAFSLVVAVDEH-----------------G-GIGDGRSIPW-NVPEDMKFFRDLTTKLRgkn----------- 63 72391754 20 KISRPPLRPFSVVVASDEK-----------------G-GIGDGGTIPW-EIPEDMQYFRRVTTNLRgkn----------- 69 145535888 1 ---MTTNKTFSMVLAMTLN-----------------G-GIGYQNRLPW-KLKEDLQRFKKITT----------------- 41 154331155 18 SFAFPSLRCFSIIVAVDEQ-----------------H-GIGDGKTIPW-QVPEDMAFFKDQTTLLRnkk----------- 67 156084246 2 SNSYEGCGDLTIFVAVALN-----------------K-VIGHKNQIPWpHITHDFRFLRNGTTYIPpev----------- 52 157864294 18 DFAFPSLRAFSIVVALDMQ-----------------H-GIGDGESIPW-RVPEDMTFFKNQTTLLRnkk----------- 67 118349035 1 ----MKTRHFDIVLAQTLK-----------------KqGIGYKNSLPW-RLPNELKNFKKITTETK-------------- 44 209878892 13 SEDLKLQKPVIIIVAASTK-----------------EkGIGKGNNLPW-SIKEDLKFFREITCSTIeqsqd--------- 65
221053708 80 lqreasvgnvethcggdtvetednTTKLQNVVVMGRSSWESIpkQYKPLPNRINVVLSKTLTH--------------EQV 145 66356564 55 ------------------------DSNKKNALIMGRKTWDSI--GRRPLKNRKIVVISSSLPQ--------------DEA 94 71653378 64 ---------------------vkpSPAKRNAVVMGRKTWDSIppKFRPLPGRLNVVLSSTLTTqhlldglpdeekrnLHA 122 72391754 70 ---------------------vkpSPSKRNAVVMGRKTWDSLppKFRPLSNRLNVVLSRSATKeqllagipdpikraEAA 128 145535888 42 ----------------------------GGIVIMGRKTFESM--NSKPLPNRVNVVISKNMKS----------------- 74 154331155 68 ----------------------ppTEKKRNAVVMGRQTWESVplKYRPLKGRLNVVLSSKATVdellaal-pegkrtAAA 124 156084246 53 ---------------------lskNPDIQNVVIFGRKTYESIpkASLPLKNRINVILSRTVKE----------------- 94 157864294 68 ----------------------ppTEKKRNAVVMGRKTWESVpvKFRPLKGRLNIVLSSKATVeellapl-pegqraAAA 124 118349035 45 ------------------------NKGLQNAVIMGKNTWEALpkKQQPLKDRLNIVISTTMQE--------------GQI 86 209878892 66 -------------------dkentKIEKVNAIILGRKTWDSM--KRIPLKNRKVIVLSRTLQRc------------dNKN 112
221053708 146 KEKVFIIQSIDDLLLLLKK----LKYYKCFIIGGAQVYKECLNR---NLIKQIYFTRI-NNAYQCDVLFPQFDEGQFRMT 217 66356564 95 DPNVIVFRNLEDSIKNLMNd---DTIENIFVCGGESIYRDALKD---NFVDRIYLTRVaLEDIEFDTYFPEIPETFLPVY 168 71653378 123 DSIVAVNGGLEQALRLLASpnytPSIETVYCIGGGSVYAEALRPpcvHLLQAIYRTTIrASESSCSVFFRVPESGTEAAA 202 72391754 129 NDVVAVNGGLEDALRMLVSkehtSSIETVFCIGGGTIYKQALCApcvNVLQAIHRTVVrPASNSCSVFFDIPAAGTKTLE 208 145535888 75 SNEVQVFPRIEDALQFYN-----TSHQKLYLIGGKRIFEEGLAT---DKCSDVHLTRI-GVETKCDVYLNKNIFSTFQVN 145 154331155 125 QDLVVVNGGLAEALHLLARpphcSSIETAYCVGGAQVYSDAMTApcvEKLQEVYLTRIyATAPECTRFYPFPPTNAAAAA 204 156084246 95 VPGCLVYEDLSTAIRDLRAn---VPHNKIFILGGSFLYKEVLDN---GLCDKIYLTRL-NKEYPGDTYFPDIPDTFEITA 167 157864294 125 QDVVVVNGGLAEALRLLARplycSSIETAYCVGGAQVYADAMLSpciEKLQEVYLTRIyATAPACTRFFPFPPENAATAW 204 118349035 87 ADHSYACKSLDSALNFLEQq---NQIQDALVIGGAKLCQQALSD---QRLRQIHLTRV-GVEVECDVFMQKDYLKNFDMI 159 209878892 113 DSGVSIVKSLDEAINLCNNd---ISIHKIVICGGESIYRECIEK---NIVETIYLTRVsTSKKEFDTYFPNIPESFVPIL 186
221053708 218 Sv----------SEVYNNKGTTLDFVIYSKvggevdggaSNgstmdmdsgsencenvkcgapncntsgcispnctstree 287 66356564 169 M-----------SQTFCTKNISYDFMVFEK---------QEkktlqncdp------------------------------ 198 71653378 203 GiewqretiseeLTSANGNETKYYFEKLIP---------RN--------------------------------------- 234 72391754 209 GlelvresitdeRVSTGAGGKKYQFEKLVP---------RN--------------------------------------- 240 145535888 146 Kt----------SQTKSENGINYDYQHLIN---------KN--------------------------------------- 167 154331155 205 Wdlaw----tqgRQRSETGGVEYEIRKYVP---------HN--------------------------------------- 232 156084246 168 I-----------SPTFSTDFVSYDFVIYER---------KDcktvf---------------------------------- 193 157864294 205 Dlas-----sqgRRKSEAEGLEFEICKYVP---------RN--------------------------------------- 231 118349035 160 Ev----------SETQSENNLNYDFTRYFN---------KN--------------------------------------- 181 209878892 187 M-----------SQTFCCNDISYDFMIYEN---------EIlkpikrnir------------------------------ 216
221053708 288 kwrkcspacqwkksnADVEEDDLVYFSFNNKVGEKNPEHLQDFKIYNSVKIKQHPEYQYLSIIYDIIMNGNKQGDRTGVG 367 66356564 199 -------vrgqlksiDDTVDLLGEIFGIRKMGNRHKFPKEEIYNTPSIRFGREHYEFQYLDLLSRVLENGAYRENRTGIS 271 71653378 235 -----------------------------------------------------REEEQYLSLVDRIIREGNVKHDRTGVG 261 72391754 241 -----------------------------------------------------SEEEQYLNLVGRIIDEGCTKCDRTGVG 267 145535888 168 -------------------------------------------SHEQSYIDEEHQENQYLDMITKIMKEGVSKDDRTGVG 204 154331155 233 -----------------------------------------------------HEERQYLELIDRIMKTGIAKEDRTGVG 259 156084246 194 ---------------------pdppFDQLLMTGTDISVPKPKYVACPGVRIRNHEEFQYLDILADVLSHGVLKPNRTGTD 252 157864294 232 -----------------------------------------------------HEERQYLELIDRIMKTGIVKEDRTGVG 258 118349035 182 -------------------------------------YKGQVDPSLFKKMYKPHQEYQYLELIDEIIKNGHVKTDRTGTG 224 209878892 217 ------ntsceseviIPFENVLDKIFGERKISLRNKVPKDDIISYPSIII-RDHPEFQYLDMLSNVLQNGHYRENRTGIN 289
221053708 368 VMSKFGYMMKFNLNEY-FPLLTTKKLFLRGIIEELLWFIRGETNGNTLLKKNVRIWEANGTREFLDNRKLFHREVNDLGP 446 66356564 272 TYSIFGQMMRFDMRES-FPLLTTKKVAIRSIFEELIWFIKGDTNGNHLIEKKVYIWSGNGSKEYLERIGLGHREENDLGP 350 71653378 262 TLSIFGAQMRFSLRNNrLPLLTTKRVFWRGVCEELLWFLRGETYAKKLSDKGVHIWDDNGSRAFLDSRGLTEYEEMDLGP 341 72391754 268 TRSLFGAQMRFSLRNNrLPLLTTKRVFWRGVCEELLWFLRGETNAKLLSDKGIHIWDGNGSRAFLDSRGLTDYDEMDLGP 347 145535888 205 TMSIFGQTMRFNLAQS-FPLLTTKKVFFRGVVEELLWFLRGNTNGKLLLDKGVKIWEGNGTREYLDTIGLQHRQEHDLGP 283 154331155 260 ILSLFGAQMRFSLRDNrLPLLTTKRVFWRGVCEELLWFLRGETNAQLLADKDIHIWDGNGSREFLDSRGLTANKEMDLGP 339 156084246 253 AYSKFGYQMRFDLSRS-FPLLTTKKVALRSIIEELLWFIKGSTNGNDLLAKNVRIWELNGRRDFLDKNGFTDREEHDLGP 331 157864294 259 TISLFGAQMRFSLRDNrLPLLTTKRVFWRGVCEELLWFLRGETSAQLLADKDIHIWDGNGSREFLDSRGLTENKEMDLGP 338 118349035 225 TISQFGKLMRFDLSKS-FPLLTTKNVFWRGVVEELIWFIKGSTNSKILSEKGVKIWDGNGSREFLDQLGFKNREEGDLGP 303 209878892 290 TYSIFGASMRFDLRES-FPLLTTKNVALRIIFEELMWFIKGDTNGNHLLDKKVFIWAGNGSKEYLNKVGLGYREENDLGP 368
221053708 447 IYGFQWRHFGAEYTNMYDNYEDKGVDQLKNVIHLIKNEPTSRRIILCAWNVKDLDQMALPPCHILCQFYVFDG--KLSCI 524 66356564 351 IYGFQWRHYNGEYKTMHDDYTGVGVDQLAKLIETLKNNPKDRRHILTAWNPSALSQMALPPCHVLSQYYVTNDn-CLSCN 429 71653378 342 VYGFQWRHFGAAYTHHDANYDGQGVDQIKAIVETLKTNPDDRRMLFTAWNPSALPRMALPPCHLLAQFYVSNG--ELSCM 419 72391754 348 VYGFQWRHFGADYISCKEDSEGKGVDQIANIVKSLIENPDDRRMICTAWNPAALPRMALPPCHMMAQFYVSNG--ELSCM 425 145535888 284 VYGFQWRHFGAKYKDCQTDYSNQGVDQVKEIIQLLKNNPDSRRIILSAWNPIDLKQMALPPCHVMSQFFVANG--KLSCM 361 154331155 340 VYGFQWRHFGAQYKGFEANYDGEGVDQIKSIVETIKVNPNDRRLLLTAWNPCALHEMALPPCHLLAQFYVNTDakELSCM 419 156084246 332 IYGFQWRHFGAEYLDMHADYTGKGIDQLAEIINRIKTNPNDRRLIVCSWNVSDLKKMALPPCHCFFQFYVSDN--KLSCM 409 157864294 339 VYGFQWRHFGADYKGFEANYDGEGVDQIKLIVETIKTNPNDRRLLVTAWNPCALQKMALPPCHLLAQFYVNTDtsELSCM 418 118349035 304 VYGFQWRHFGAEYKDMHTNYKGKGVDQLQDLINTIKKNPDSRRMIMNAWNVKDLPLMALPPCHVMSQFYVNDN--KLSCM 381 209878892 369 IYGFQWRHFNAEYKTMHDNYNGQGVDQLANLIESLKKNPYDRRHILSAWNPSAVKYMALPPCHILSQFYVDNNn-RLSCS 447
221053708 525 MYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQPAQFIHILGNAHVYNNHIDSLKVQLNRIPYPFPTLKLNPEVKN--IE 602 66356564 430 LYQRSCDLGLGSPFNIASYAILTMMLAQVCGYEPGELAIFIGDAHIYENHLTQLKEQLSRTPRPFPQLKFKRKVEN--IE 507 71653378 420 LYQRSCDMGLGVPFNIASYALLTILIAKATGLRPGELVHTLGDAHVYSNHVEPCNEQLKRVPRAFPYLVFRREREF--LE 497 72391754 426 LYQRSCDMGLGVPFNIASYALLTFLMAKASGLRPGELVHTLGDAHVYSNHVEPCRKQLKRVPRPFPFIVFKQDKEF--LE 503 145535888 362 MYQRSCDFGLGIPFNIASYALLTYMLAKECNLNLGEFVHVLGDTHIYSNHVEALKKQIERVPYPFPLLKIKGNKS---LF 438 154331155 420 LYQRSCDMGLGVPFNIASYALLTILMAKATGLRPGELVHTLGDAHVYRNHIDALKVQLERTPNAFPTLVFKREREF--LE 497 156084246 410 MHQRSCDLGLGVPFNIASYSILTAMVAQVCGLGLGEFVHNLADAHIYVDHVDAVTTQIARIPHPFPRLRLNPDIRN--IE 487 157864294 419 LYQRSCDMGLGVPFNIASYALLTILIAKATGLRPGELVHTLGDAHVYRNHVDALKAQLERVPHAFPTLIFKEERQY--LE 496 118349035 382 MYQRSCDMGLGIPFNIASYALLTHMIAQVTNMQVGEFIHVLGDAHVYSNHVDQLKIQLERAPYPFPLLKINNNKQYnsIE 461 209878892 448 LYQRSCDLGLGCPFNIASYSLLCVMIAHICGYEPGEFIHFIGDVHIYENHVEQLKQQIKRLPRPFPQLRLKRKVDK--VE 525
221053708 603 DFTISDFTIENYVHHDKIAMEMAA 626 66356564 508 DFKWEDIELIGYYPYPTIKMEMAV 531 71653378 498 DYEEGDMEVIDYAPYPPISMKMAV 521 72391754 504 DFQESDIEVIDYSPYPVISMEMAV 527 145535888 439 DYTYEDFELVGYNAHDKIEMKMAV 462 154331155 498 DYELSDMEVIDYAPYPPIKMEMAV 521 156084246 488 DFTIDDIVVEDYVSHPPIPMAMSA 511 157864294 497 DYELTDMEVIDYVPHPAIKMEMAV 520 118349035 462 DFTLEDFELIGYNYHPKIQMKMAV 485 209878892 526 DFIWEDIEIIGYYPHPTIRMEMAV 549