Conserved Protein Domain Family
DUF6399
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pfam19936: DUF6399 
Family of unknown function (DUF6399)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000967) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide, in particular the calyculin A biosynthetic gene cluster from uncultured Candidatus Entotheonella sp.. This family appears to be predominantly found in proteobacteria and cyanobacteria.
Links
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Statistics
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PSSM-Id: 437768
Aligned: 12 rows
Threshold Bit Score: 198.711
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EGV18510                259 MLDDLIPALYLERVAARSTRAEPRHRLRALSAQRLAPLQQlsHPIQ-SLDPQTRHHLEQVAGECADLFQRSSSCVEGRNG 337
ORU93959                322 VIDALLPVVYWHHQLHKTQNRQLREKYQQAWKSSSAVLRQ--HPLTdALSVCKLQHWLTWAEWMVQHFHRSSSAVEGRNG 399
ORU92833                 39 LTSCLLPVVYWHHKMEQSKKPKAKKKCRKAWEQASIEIKV--HPFSeSLSISEMERWLTWAENMVRQFHRSSSAVEGRNG 116
ORU94954                311 LTTVLLPVVYWHHKVEQTKKPKVKEKYRKAWEQATDLFKE--HPLSaTLSESEMQHWLTWADNMVRQFHRSSSAVEGRNG 388
WP_015203604            157 LLGYFLPHFYWLSVIKQTKNPALKEIYTQVSRHYLRHLLE--HPLTsKFSKNEWIHWRSWAEQMSAQFQRSSSAIEGRNG 234 Crin...
ESA34171                227 VLMALLPWVYWTQQADKTRQPALKHRYQQAASSTFDRLLE--QSITlQLDANELECWVLWCRDFCAKYQRTSSAVEGRNG 304
WP_006526961              9 VKHQLLATAYWYQQSQRADNSQLREKYEKAYHNARQTWLV--HPLTlNLTPESQNDWWNWALWMVSKFQRCSSPIEGRNG 86  Gloe...
ETW99195                202 MDTLLLPLMYWQEQASHTREPRRKAEILKALKATQAAFEA--HTLTqYLSSDVLEGWKQWAMEHVRAFQRASSAVEGRNG 279
ASC72638                368 LTVGLLPLCYWQYQSQRTDKPTLKAQYRDAYQRAHNVLKA--HPLTrTLEAEVYRYWYSWASEMVTKFQRTTAAVEGRNG 445
WP_009150015            417 MHEQLIPARYLERVATRQSRAEERDRLEALSERLLAPLRApdHPFQ-QLDAATQATLEQVAGDCADVFQRSSSAVEGRNG 495 Thio...
EGV17470                400 VLEQLIPAIYLERVAARSTAAETRHRVQAVSTALLDALRRadHPLQ-RLAPANSARVEQVAGACADLFQRSSSCVEGRNG 478
PRJNA354524:THSYN_09675 400 LLTQLIPALYLERVANRSTLAEPRHRLHALSRQLLEPLRQrdHPLQ-ALPEAERARLEQVAGDCADLFQRSSSSVEGRNG 478

EGV18510                338 FLALYQHGHHRLGPSKQQVLTALHNFAIKRPDGTTAAERFFAQPHPSLFEQVLERMPWPARPARRRPR 405
ORU93959                400 SLSKMYHNGRGISESRLKALTVIHNYGLKRRDGTTAAQRFFEQDSPDLFSWILDEMGELPLPRQARPK 467
ORU92833                117 CLSQMYHNGRGLSEKRLKALTVIHNYGIKREDGTTAATRLFDIEFPGLFSWLLDEMGELPLPRKGRER 184
ORU94954                389 CLSQMYHNGRGLSEKRLKALTVIHNYEIKRENGTTAAMRLFGTNFPDLFSWLLNEMGELPLPRKERGV 456
WP_015203604            235 YLSRLHHCGRGISSAQLRVLTVIHNFDIQRADKTTAAQRLFNQEFPALFDWVISQMGDLPLPRKSYQI 302 Crinalium epipsa...
ESA34171                305 YLSKLHHASRGFSEQSLKGLTIIHNFDLKRPDGTTAAQRLFGHPFPDVFEWILEHIGDLPMPRRSSKT 372
WP_006526961             87 YLSQIHHNRRGLSSQRLKVATVIHNYVIRRSDGTTAAERLFCLKFPDLFEFLVHHLGELPQPRRARKS 154 Gloeocapsa sp. P...
ETW99195                280 YLSQMQHNHRGLPKRRYQVWSALHNFDCHAADGSTPASRFFRHEFPDLFETVLAQIDELPRPRERRQV 347
ASC72638                446 YLGQIHHSRRRLSDRQLQVMSVIHNFDLKRLDGSTAAQRLFKQPHPDLFQTVLAQMHDLPLPRQRAKA 513
WP_009150015            496 QLSLFHHGRHRLSERKLSALTAIHNFHIRRSDETTAAERLFGCAHPSLFEEVLKRTPLPPPARRRRAR 563 Thiorhodovibrio ...
EGV17470                479 QLSLHHHGRHRLSDRRLAALTAVHNFHIRRPDSTTAAERFFGRTHPALFEQLILRVPLPPRPRRRRPR 546
PRJNA354524:THSYN_09675 479 QLSLHHHGRHRLSDRKLEALTAVHNFHLRRPDGTTAAERFFGRAHETLFAQVLQRMPLPPPPARRRPR 546
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