Conserved Protein Domain Family
Intg_mem_TP0381

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pfam09529: Intg_mem_TP0381 (this model, PSSM-Id:430666 is obsolete)
Integral membrane protein (intg_mem_TP0381)
This entry represents a family of hydrophobic proteins with seven predicted transmembrane alpha helices. Members are found in Bacillus subtilis (ywaF), TP0381 from Treponema pallidum (TP0381), Streptococcus pyogenes, Rhodococcus erythropolis, etc.
Statistics
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PSSM-Id: 430666
Aligned: 79 rows
Threshold Bit Score: 73.8271
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
umc-mjc:MYB_02935  17 YAKLFFYipvVFAIVALIGMHLFRKsLRTWYANQTLNIDspsfKKiKIIFLSVGLFIWLFSyvsrvallEA--------- 87 
CCZ65555           23 GVHFIWI---AGIAISIFLLCKVY---LRLAKNKRLQML----NAfVLLALCCTFTQDAIL--------TV--------- 75 
WP_014080075       29 PVHLLWL---GVCAGLLLLFLHYY---KRWGGRRRLLAE----RGiGIFLVGLEVYRIAVL--------AL--------- 81  Roseburia ...
WP_082413830       52 PWHLLWL---SVIFAICVRYVWIY---KKGDERKKRRMD----GLtACSLVVWIVVRAIYI--------AV--------- 104 Roseburia ...
CDA25120           27 IWHILCL---LLCLAVTVVSLHWY---WKAKAQKKQKFE----KTiAMSLVGWMILRAIYI--------AV--------- 79 
WP_117784459       34 WIHICWL---VGIIFVCIVTGYYY---RKADAAVQDRIL----KIlTGICLCLELGKDFYL--------IW--------- 86  Clostridiu...
CCX67206           25 SRHFAAVfccGFGVAFALGLF------LKCSKKRQDVLL----KAtALSLLAGNLLRDLFL--------FS--------- 77 
CCX85894           22 VCHILWL---SAIILTGILLVRWY---CKQSEKMCHRIR----AViGILLPVMAIYRDGIL--------VI--------- 74 
WP_014025032       21 ADHFFAL---AILALISFGLIRAY---LRANDGRRKLLR----LLvASFTLLLEIIRDIIL--------VM--------- 73  Lactococcu...
CDE05210            8 AAHIGLF---VFAAAAVLFLRLILRdRSEKARK----------LVlIVICCVNIVCFFAYK--------FAlsrdaefla 66 
umc-mjc:MYB_02935  88 ---NDYFNKWEYLPLHLCRILVLA-TATALIFN-----KTNYVKYWVVPAFIGSSLALASPQisistetylqtintnfpt 158
CCZ65555           76 ---TGHMNARM-LPFHLCDLATFF-YLFLQMRIlrtghCDSLAEIALCLFMPGAVLGILFPV------------------ 132
WP_014080075       82 ---IGKMSLYQ-LPLHLCSMAGFL-CCLHAFFK-----WDWLGQVLYTLCLPGTVLALLFPD------------------ 133 Roseburia ...
WP_082413830      105 ---IHEAFLYE-LPFHLCSMAGIL-CAVHCLTK-----WKWLGQVLYTICLPGTVLALLFPN------------------ 156 Roseburia ...
CDA25120           80 ---IGENFLYE-LPFHLCSMTGIL-CGIHCFTK-----WKWLGQMLYALCLPGAILALLFPN------------------ 131
WP_117784459       87 ---IGEMGISY-LPFEMCGLAIFV-ELGFAFFH-----RKFLGEVMCVISMPGAMAALLFPD------------------ 138 Clostridiu...
CCX67206           78 ---VHRMSLAY-LPLHLCSFAIFVyLLQAFLPErflpfRRALGEIGLVLLMPGTICALIFPD------------------ 135
CCX85894           75 ---TGHWGIGF-LPLHLCSMAMWI-APLYIFTN-----KRFLGVIYVLLCLPGAVGALLFPD------------------ 126
WP_014025032       74 ---THQFLYAD-LPFQLCGLGIFI-IVFDAMRS-----TKTSRELLYSLTLPGAIFALVTPN------------------ 125 Lactococcu...
CDE05210           67 vsgIEKFNWFNELPIQLCNINMFL-IPIGLIAK-----KRPILGFSFFVAPLGAAMALFFPEaafng------------- 127
umc-mjc:MYB_02935 159 ldlnkekfSsffpgLHWSYDSHFFWEFLITHLICLVLPIFLQIIQPSKHKLttKILVKSILILFTYALFIFFLSWII--- 235
CCZ65555          133 --------W-----NVYPPFHYMTIHGFIYHALIILYPWLLFVSGNVRPRT--KHIWQPVLFLCCIVPPVYLFNKKF--- 194
WP_014080075      134 --------W-----VRYPAIHFITIQGFTFHAGIVLYVICQLLQHNIIPRL--AALWKVIVFLLVVVPPVYLFDKKF--- 195 Roseburia ...
WP_082413830      157 --------W-----NFYPVIHFITLEGFLFHMGIVLYVAGKLASHEIRPDF--AKLWQVVLFLTAVVIPIYCFDKRY--- 218 Roseburia ...
CDA25120          132 --------W-----NAYPLIHFISLEAILFHLGIILYVTCLLTSHEIVPQM--KKMWQVIVFLAVVVPPIYVFDKKY--- 193
WP_117784459      139 --------W-----TRYPLFNYMHINSFLIHGLLVLIPVLVLTSGRYKPSI--KRIWQIFLFLFTVVPSVYVINRIW--- 200 Clostridiu...
CCX67206          136 --------W-----TAYPLWNFMCIHSFVWHAVLVFYPLALFLSGRLRPTI--RHLWYPVLYLGIIVPPTAVFNHFT--- 197
CCX85894          127 --------W-----NMYPVWNYMHIHAFLSHGLLVIFGCMLIISGEMIPTW--REFYIPIVFGAIGFTIIHRVNLMF--- 188
WP_014025032      126 --------W-----VTNNFINVFVWQSFLIHCLLISYVLMRLIAGDLVPQW--REFWRSAIFLAIVVPICAVLNQVW--- 187 Lactococcu...
CDE05210          128 ----------------yslfLPRMLGFCLTHLVILICGISLAALGLYRPKF--SDFPGILITFICLAIGAHCVNLILrat 189
umc-mjc:MYB_02935 236 ----FTelnnhhvdtktfiawnpNWLYLGKVG------LgelkTFGKWPYVLFSLTIIFLTLFwlvfF 293
CCZ65555          195 ----DS-----------------NYMFINYPPant-plKiladQIGN-PGYLLGYAIFIFLMI----L 235
WP_014080075      196 ----HA-----------------NYMFVNV-PspgsplEwlasFLGN-PGYLAGYAVLMLLCM----V 236 Roseburia hominis
WP_082413830      219 ----DV-----------------NYMFVNW-PsagsplVwlvdRMGN-PGYLIGYAALVFLCM----L 259 Roseburia faecis
CDA25120          194 ----QV-----------------NYMFVNR-PsggsplEwlaqWMGN-PGYLLGYAGLILLCI----F 234
WP_117784459      201 ----GC-----------------NFMFLCY-PsngspfLsvylQHGY-VPYLITYAVTVILCI----L 241 Clostridium sp. AF15-31
CCX67206          198 ----GC-----------------NYLFIMT-PlkgtplEllysRMG--ACWRIGYALLVLAVI----L 237
CCX85894          189 ----RT-----------------NYWFLNE-PsadsplIwiqhITGS-KWYQLGYFMFCVGIVavwmc 233
WP_014025032      188 ----NQ-----------------NFFFLRT-PvpgsplEpisnMFG--SYYILGLIFIVLIFW----L 227 Lactococcus garvieae
CDE05210          190 vcpyA------------------NYFFTYHvdi--silNlfwsWIPLPLLYLLPGIVILLAYMllvsL 237
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