4N83,4BMO


Conserved Protein Domain Family
RNR_1b_NrdF

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TIGR04171: RNR_1b_NrdF 
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ribonucleoside-diphosphate reductase, class 1b, beta subunit
Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism]
Statistics
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PSSM-Id: 275027
Aligned: 54 rows
Threshold Bit Score: 466.261
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4N83_A         5 YKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSHKEKDLVGKVFGGLTLLDTLQSESGVDALRKDVRTA 84  Streptococcus s...
ZP_03646972   17 VSAINWNRLEDEKDLEVWDRLTGNFWLPEKVPVSNDIPSWQKMSDDEHTLTMHVFTGLTLLDTIQGTVGAVSLIPDALTP 96  Bifidobacterium...
ZP_03994558    9 VSAINWNDIEDEKDLEVWDRLTGNFWLPEKIPLSNDIPSWKTLNADEKLMTNRVFTGLTLLDTIQGTVGAVSLIPDSRTP 88  Mobiluncus muli...
WP_015772022  12 VTAINWNRIEDDKDLEVWDRLVGNFWVPEKVPVSNDIQSWATLTPQEQELTTRVFTGLTLLDTIQGTVGAVSLIPDALTP 91  Jonesia denitri...
WP_010191273  16 VKAINWNTIPDEKDLEVWDRLTGNFWLPEKVPVSNDIPSWKTLTEKEQETTMRVFAGLTLLDTIQGTVGAVSLLPDAVTP 95  Corynebacterium...
WP_011273157  18 vaAINWNSIPDEKDLEVWDRLTANFWLPEKVPLSNDVPSWSTLNDMEKQATMRVFTGLTMLDTIQGTVGAVKLIEDAATP 97  Corynebacterium...
WP_012367584   9 VNAINWNRIEDEKDLEVWNRLTMNFWLPEKIPLSNDIPSWNTLTQAEKQLTIRVFTGLTLLDTIQNTVGAPTLMPDAQTP 88  Proteus mirabilis
WP_012768762   7 lKAINWNRPQDEKDLEVWNRLTANFWLPEKIALSNDMPSWAQLTDAERQLTLRVFTGLTLLDTLQNTQGAPALMADALTP 86  Dickeya zeae
WP_015742248   7 ISAINWNKLQDEKDLEVWNRLTSNFWLPEKVPLSNDIPAWQTLTPGEQQLTIRVFTGLTLLDTIQNAVGAPALMADALTP 86  Cronobacter tur...
WP_012084858  10 VNAINWNRLQDDKDLEIWNRLTSNFWLPEKVPLSNDVQSWQNLGAQERTLTLRVFTGLTLLDTIQGTVGAVSLIPDALTP 89  Kineococcus rad...
4N83_A        85 HEEAVFNNIQFMESVHAKSYSSIFSTLNTKSEIDEIFAWTNTNPYLQKKAEIINEIYLNGTALEKKIASVFLETFLFYSG 164 Streptococcus s...
ZP_03646972   97 HEEAVYTNIAFMESVHAKSYSSIFSTLCSTKEIDAAFDWSERNEFLQKKAEIVLDYYEGDSPLKRKVASTLLESFLFYSG 176 Bifidobacterium...
ZP_03994558   89 HEEAVYTNIAFMESVHAKSYSSIFSTLLSTEEINESFQWSENNEFLQKKAHIVLDYYHGNDAEKRKVASTMLESFLFYSG 168 Mobiluncus muli...
WP_015772022  92 HEEAVLTNIAFMESVHAKSYSTIFSTLISTPEIDEAFRWSEENPHLQRKAEIILEYYRGDDPLKRKVASTLLESFLFYSG 171 Jonesia denitri...
WP_010191273  96 HEEAVYTNIAFMESVHAKSYSNIFMTLASTPMINDAFRWSEENENLQRKAKIVMSYYQGDNPLKKKVASTLLESFLFYSG 175 Corynebacterium...
WP_011273157  98 HEEAVFTNISFMESVHAKSYSSIFMTLASTPEINDAFRWSEENEKLQNKAKIILDFYEGDDPMKKKIASVLLESFLFYSG 177 Corynebacterium...
WP_012367584  89 HEEAVLSNICFMEAVHARSYSSIFSTLCLTTDVDDAYRWSEENTYLQKKSDIILRYYQDSDPLKKKIASVFLESFLFYSG 168 Proteus mirabilis
WP_012768762  87 HEEAVLSNIGFMEAVHARSYSAIFSTLCLTNEVDCAYHWSEHNKPLQSKAALILSLYRHDQPLKKKIASVFLESFLFYSG 166 Dickeya zeae
WP_015742248  87 HEEAVLSNVSFMEAVHARSYSSIFSTLCQTPDVDAAYAWSEENAPLQRKAQIILAHYRDDDPLKKKIASVFLESFLFYSG 166 Cronobacter tur...
WP_012084858  90 HEEAVYTNIAFMESVHARSYSSIFSTLATTREIDEAFAWSEDNEALQRKASIVLEYYHGDDPLKRKVASTLLESFLFYSG 169 Kineococcus rad...
4N83_A       165 FFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLAFNELPEDEQEKLKewMYDLLYTLYENEEGYTESLYDTVG 244 Streptococcus s...
ZP_03646972  177 FYLPMYFSAHAKLTNTADVIRLIIRDEAVHGYYIGYKYQRGLERVSDAKREEMReyTYNLLNELYDNEVEYTESLYERVG 256 Bifidobacterium...
ZP_03994558  169 FYAPMYWSAHAKLTNTADLIRLIIRDEAVHGYYIGYKFQVAMRESSSSRQEELRdyTYSLLTDLYDNEVLYTETLYDTLG 248 Mobiluncus muli...
WP_015772022 172 FYLPMYWSSRAKLTNTADLIRLIIRDEAVHGYYIGYKYQKGLEAVTPERREELKayTFDLLYELYDNEVAYTESLYDGVG 251 Jonesia denitri...
WP_010191273 176 FFLPMHFSSRAKLTNTADIIRLIIRDEAVHGYYIGYKFQQGYQKLSEPEQEEMKgyAFDLLYDLYENEIDYTEDLYDELG 255 Corynebacterium...
WP_011273157 178 FYLPMYWSSHAKLTNTADIIRLIIRDESVHGYYIGYKYQRALENETPERQEELKehTFDLLLELYDNEAQYTEDLYDELG 257 Corynebacterium...
WP_012367584 169 FYLPMYWSSRGKLTNTADLIRLIIRDEAVHGYYIGYKFQNQLLNKSSLEKQNIKdfAFSLLLDLYDNEVKYTEDLYDSVG 248 Proteus mirabilis
WP_012768762 167 FYLPMYWASRGRLTNTADLIRLIIRDEAVHGYYIGYKYQQGLKRLSTPEQRDLQlfAYELLQTLYDNEVDYTHELYDSVG 246 Dickeya zeae
WP_015742248 167 FYLPMYWSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQQGLAQVDDARRESLKtfALDLMMELYDNELAYTEALYRDVG 246 Cronobacter tur...
WP_012084858 170 FFLPMHFSSRAQLTNTADLVRLIIRDEAVHGYYIGYKFQRGLELVDQAKRDEIKdyAFELLYELYDNECKYTADLYDGVG 249 Kineococcus rad...
4N83_A       245 WTEEVKTFLRYNANKALMNLGQDPLFPDSadDVNPIVMNGISTGT-SNHDFFSQVGNGYLLGEVEAMQDDDYNY 317 Streptococcus sanguin...
ZP_03646972  257 LTDDVEKFLRYNGNKALMNLGYPALFPAEacDVNPAILAALSPNAdENHDFFSGSGSSYVMGKAEETDDEDWDF 330 Bifidobacterium bifid...
ZP_03994558  249 LTEDVKKFLHYNANKALMNLGYEALFPPEeiDVNPAILAALSPAAeENHDFFSGSGSSYTIGTAEETEDEDWEF 322 Mobiluncus mulieris A...
WP_015772022 252 LTEDVKKFLRYNANKALLNLGYEALFPKDetDVNPAILSALSPNAdENHDFFSGSGSSYVIGKAVNTEDEDWDF 325 Jonesia denitrificans
WP_010191273 256 WTEDVKRFLRYNANKALNNLGFEGLFPADetRVSPAILSSLSPNAdENHDFFSGSGSSYVIGKAEETTDDDWDF 329 Corynebacterium aurim...
WP_011273157 258 WTEDVKRFLRYNANKALNNLGYEGLFPADetRVSPAILSALNPGGdENHDFFSGSGSSYVIGKAENTVDDDWDF 331 Corynebacterium jeikeium
WP_012367584 249 WTEDVKKFLHYNANKALMNLGYEALFPDEitNVSPAILSSLSPDAnENHDFFSGSGSSYVIGKTINTEDDDWDF 322 Proteus mirabilis
WP_012768762 247 WSGDVIKFLHYNANKALMNLGYEALFPADmtDVNPAILAALSPGAeENHDFFSGAGSSYVIGKAVETEDEDWNF 320 Dickeya zeae
WP_015742248 247 WVDDVSAFLCYNANKALMNLGYEALFPPEmaQVNPSILAALSPGAdENHDFFSGSGSSYVMGKAVETEDADWDF 320 Cronobacter turicensis
WP_012084858 250 LTEDVKTFLHYNANKALMNLGYEGMFPSDmtKVDPSILSALSPNAdENHDFFSGSGSSYVIGKAVATEDEDWEF 323 Kineococcus radiotole...
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