Conserved Protein Domain Family
PRK04346

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PRK04346: PRK04346 
tryptophan synthase subunit beta; Validated
Statistics
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PSSM-Id: 235288
Aligned: 888 rows
Threshold Bit Score: 530.794
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
284164144  11 ERDSEATF--------GDYGGQYVPEALMPALQELEEAYERyvLENEDGFMDEFRERMRDFGGRPTPLQRADRLSERY-D 81 
302340591   5 DSKKSGYF--------GRFGGAYVAEVLRPALLELETAFGK--AMKDQSFLAELDRIGKEYIGRPTPLLHAKNASRAIgG 74 
32266914    7 TESKNGYFgeakggnhA-FGGQYIPEILLPALKELEKAYHG--VFVSKAYKKELKSLFKHFVGRPTPLIYAHNASKILkN 83 
291276804   5 THSKNTFFgk------qkFGGQYVPEILYPALKELEEAYHS--IFASKEFKKEFDELCKHFIGRPTPLVYARNASRILhN 76 
261414592   4 TTSNNGFF--------DKFGGKYVAEIIRRPLDDLEAAFNK--YIHDPEFLEELRIIQRDYIGRETPLYFAPTATKLLgG 73 
256830581   5 SDMLPRHF--------GPYGGRYVPEMLVPALEELEQGYQK--YKDDPEFTAELTDLYQNYCGRPTPLYFAENLTRELgG 74 
296125404   2 KNSNKGFF--------GKFGGRFVPEALEKLLIELEEAFAH--YINDKEFLSELEELRADFIGRPTPLMYAKNLSEKIgG 71 
300871925   2 ITSENGFF--------GEFGGRFVDEKLEKKLIELEEAFKF--YIKDKDFLNELEELRSDFLGRPTPLMYAKNISESIgG 71 
225619712   2 KNSNKGFF--------GKFGGRFVPEALEKLLIELEEAFLH--YINDKEFLSELEELRADFIGRPTPLMYAKNLSEKIgG 71 
188585354   1 -MTKIGFY--------GEFGGQHVDEALKPSLEELTEFYYK--YKDDSDFYKEFEYHLHTFGGRPTPLYYAKNLTEKLgG 69 
284164144  82 REIYLKREDLVHGGAHKLNNALGQVLLAKYMGKERIIAETGAGQHGTATAMAAAHLDMPCEIYMGRTDVNRQRPNVYRMR 161
302340591  75 AEMYIKLEGLANTGAHKINNAVGQAMLAKRMGKTRIIAETGAGQHGLATAAACARLGLECVIYMGEKDHRRQRPNVMYME 154
32266914   84 -DIYLKFEGLANTGAHKINNALGQVLLAKHMKKKRVIAETGAGQHGLATAAACARLGLECEIFMGEIDIARQRPNVFNME 162
291276804  77 -DVYLKLEGQAITGAHKINNALGQAMLAKKMGKTRVIAETGAGQHGLATACACAKLGLECEIFMGSIDMARQRPNVLNME 155
261414592  74 AQIYIKLEGLANTGAHKINNAIGQCLLAKKMGKTRIIAETGAGQHGLATAAACAKLGLECVVYMGEVDVRRQQPNVATME 153
256830581  75 CKIYLKLEGLAHTGAHKINNALGQALLAKRLGKTKVIAETGAGQHGLASATVAARFGLECRVFMGEVDVRRQYPNVYAMK 154
296125404  72 AKIYVKLEGLANTGAHKINNSIGQALLAKKMGKKKIIAETGAGQHGLATAAACAKLGLECSIYMGEIDVKRQQPNVASME 151
300871925  72 AKIYVKLEGFAHTGAHKINNSIGQALLAKRMGKKKIIAETGAGQHGIATAAACAKLGLECSIYMGDIDVRRQQPNVASME 151
225619712  72 AKIYVKLEGLAHTGAHKINNSIGQALLAKKMGKKKIIAETGAGQHGLATAAACAKLGLECSIYMGEIDVKRQQPNVASME 151
188585354  70 GKIFLKREDLNHLGAHKLNNTIGQILLAQKMGKQEIVAETGAGQHGVATAAVSAKFGFNCTIFMGALDAKKQPLNVFRME 149
284164144 162 MNGAEVNPVEAGSGTLKEAINETMRDWATTVENTHYVIGSVVGPHPFPKLVRDFQAVIGREAREQIRE-KAG-RLPDSVV 239
302340591 155 FFGATVIPVKGGSGTLKDAVNEALRDWAGSFSNTHYLIGSALGPAPFPAIVKAFQSVIGRETEQQLSE--AG-VKADLLV 231
32266914  163 LFGAKVHSVSSGSKTLKDAVNEALREWSKRSDDSFYVLGSALGPYPYPDIVRDLQSVISKELKKQTKA--YFsSLPDILV 240
291276804 156 LFGAKVRSVDSGSKTLKDAVNEALREWSKDMHQTFYVLGSALGPYPYPDIVRDLQSIISKEVKKQVKYyFKG--LPDFMV 233
261414592 154 MYGAKVVPVTSGSRTLKDAVNEAMRDWATNFQNTHYVLGSALGPAPFPDIVRTFQSIIGEEVKRQAAErNID--I-AAVV 230
256830581 155 LLGAEVIPVTDGTRTLKDAVNATLKYWIQNLKDTHYILGSALGPFPYPVIVRDFQSVIGREARAQILE-REG-RLPNHLV 232
296125404 152 LYGANVVSVTRGGRGLKDAVDAALEDWVKDLKDTHYLLGSAVGPSPYPDIVRTFQSVIGRELEKQIEQ--KN-LNVKAMI 228
300871925 152 LYGANVVSVKRGSRGLKDAVDAALEEWIKDLDDTHYLLGSAVGPSPYPDIVRTFQSIIGRELEKQIAE--KN-LKVKSMF 228
225619712 152 LYGANVVSVTKGGRGLKDAVDMALEDWVKDLKDTHYLLGSAVGPSPYPDIVRTFQSVIGRELDKQIQE--KN-LNVKALI 228
188585354 150 LLGAKVIKVESGNQTLNDAVNEALSYWVENLENTHYLLGSCVGPHPYPTIVRDYQSVIGREAKVQINE-LEG-KNPDHIV 227
284164144 240 ACAGGGSNTMGTFHEFVPdcadprfanessgrsprDDDV------ALYAVEAGGSSLeidaEEGlaPNSATLS-TGTD-- 310
302340591 232 ACVGGGSNSIGFFSPWID-----------------EPTLnehlktRLLGAEAGGKGR----APG--EHAARMDgSGKE-- 286
32266914  241 ACVGGGSNAMGFFTHYLK-----------------EERV------RLIGVEAGGIGD----KEG--ENAIRIN-TINAse 290
291276804 234 ACVGGGSNAIGFFHAFLK-----------------EKV-------QLIGVEAGGRGM----QRG--EHAARMQgTEDAhv 283
261414592 231 ACVGGGSNSIGVFTPFIE-----------------DKNV------RLIGAEAGGVGP----NVG--ENAARMT-GNASre 280
256830581 233 ACVGGGSNSIGLFHPFLQ-----------------DTGI------RFHGAEAGGRGP----AIG--DNAARFG--GKPkv 281
296125404 229 ACVGGGSNAIGFFEPFIE-----------------RENP------KLIAVEAGGISM----NLG--ENAIRMQ-NPYAkd 278
300871925 229 ACVGGGSNAIGFFEPFIE-----------------KTDI------ELVAIEAGGIGS----NIG--ENAVRMN-NQYAkd 278
225619712 229 ACVGGGSNAIGFFEPFIE-----------------RENP------KLIAVEAGGISM----NLG--ENAIRMQ-NPYAkd 278
188585354 228 ACVGGGSNAIGLFSAFID-----------------NSEV------KIHGVEAGGKSL----TKG--DHAATLT-QGEP-- 275
284164144 311 GVLHGAMTKLLQSEEGQIMESHSVSAGLDYAGVGPELSYLAETGRVTPVSVDDEAALNGFHRLSRLEGIIPALESSHALG 390
302340591 287 GIFQGYKSLFLLDEDGQVYGTHSISAGLDYPGIGPRLAWEHEQGRIEFTRVSDEQALEALRFFAKTEGTLFALESAHAGY 366
32266914  291 GIAQGYKSLFLQDKDGQLSDTHSISAGLDYAGIGPQLAHLYEVGRVEFQSATDKEALEALSFFAQYEGIIPALESSHALA 370
291276804 284 GIAQGYKSIFLQDDEGQLSPTHSISAGLDYAGIGPQLAHLGSIGRVKFDSATDNEVLEALKFFAKHEGIIAALESSHALA 363
261414592 281 GIVQGYKSRFLIDEDGQSMPTRSISAGLDYMGIGPQLAALGESGRVEFTAILDKEALEAVKFFARNEGILFALESAHAGA 360
256830581 282 GIVQGYKSYFLQDESGQLQNTHSVSAGLDYAGVGPELAWLHDQNIIEFAPITDVKALDAFKRLTRLEGIIPALESSHAVA 361
296125404 279 VAAQGYMSKFILKENGEISETMSISAGLDYPGVGPQLAYLGEAGRIEFTYATDKEAINAVKEFARNEGVIFALESAHAGA 358
300871925 279 HVAQGYKSKFILKENGEISDTMSISAGLDYPGIGPQLAYLGDIGRIKFLSATDMEAINAVKEFAKHEGVIFALESAHAGA 358
225619712 279 VAAQGYMSKFILKENGEISETMSISAGLDYPGVGPQLAYLGESGRIEFTYATDKEAINAVKEFASHEGVIFALESAHAGA 358
188585354 276 GMLHGAYTYYLKGEGDAPHDTHSISSGLDYPGVGPEHSHLKASGRASYVAVTDQEALEAYRDLAFCEGIVPALESSHALA 355
284164144 391 YVEE-AHD-ELGDLVVVNVSGRGDKDLETVL---------------------------------E 420
302340591 367 AAMQeAKRlGPGKVIVINMSGRGDKDLFITAanekpkewaeflrreaeals-------------- 417
32266914  371 AVIRlCKDi-KGKKIIANISGRGDKDIFITAk-------------------------------aL 403
291276804 364 GAMKlCKN-HQGKKIIINISGRGDKDIFITAkhlqpaiwaeflq--------eeiarikdahkeV 419
261414592 361 AAMKiAKElPKDKALVINMSGRGDKDIFITSpvfrpekwkeflkaelvrlennedihdaeimtrK 425
256830581 362 RAIElAPTlPKDEIMIVNISGRGDKDIFITAmeldrenwiaflenevrhgk-------------- 412
296125404 359 KAIEyAKQyTKDDVIIVNMSGRGDKDIFITSpifradkwkeflks------elerleknidihkF 417
300871925 359 KAIEyAKKcSKDDVIIVNMSGRGDKDIFITSpifrakrwkeflqdelnrlennidihnfk----- 418
225619712 359 KAIEyAKQySKDDVIIVNMSGRGDKDIFITSpifrpnkwkeflks------elerleknidihkF 417
188585354 356 YLNKlAPNtDKDELIIVNLSGRGDKDVEAVAkh-----------------------------tgL 391
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