7JGG,7JGG


Conserved Protein Domain Family
Duffy_binding

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pfam05424: Duffy_binding 
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Duffy binding domain
This domain is found in Plasmodium Duffy binding proteins. Plasmodium vivax and Plasmodium knowlesi merozoites invade human erythrocytes that express Duffy blood group surface determinants. The Duffy receptor family is localized in micronemes, an organelle found in all organizms of the phylum Apicomplexa. This family is closely associated on PfEMP1 proteins with PFEMP, pfam03011.
Statistics
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PSSM-Id: 428465
Aligned: 92 rows
Threshold Bit Score: 120.456
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7JGG_A      97 VFVPPRRQRMCINNLEKLnvdkirDk-------HAFLADVLLTARNEGERIVQNHPDTN---------------SSNVCN 154 
Q8IIZ4     903 VYMPPRRQKLCVINLEHFken----------tsDDLREAFIKCAAAETYLLWQKYKEDNnggedlqnqlksgkiPEDFKR 972  Plasmodium falci...
Q8I098    1758 ACMPPRRIKLCVINLQYLnek---------kspEELRKAFIQCAAIETYWLWQKYKKDKnggvaqa-klnsgtiPDDFKR 1827 Plasmodium falci...
Q8IAK2    1289 ECMPPRRQKLCLYFLAHK------IetpnlntqEDLRKAFIKCAAAETFFSWYYFKKINdklnkldeklkegeiPPQFLR 1362 Plasmodium falci...
Q8IEU9    1257 ACMPPRRQKLCVYFFANP------SqigsinkqDNLRKAFIISAAAETFRSWQYYKSKNggenlqt-qlkdgtiPDDFKR 1329 Plasmodium falci...
Q8I220     903 VCMPPRRQKLCLYYIAHE------SetknietqDDLRDAFIRTAAAETFLSWQYYKIKNgadakq---ldngtiPEEFLR 973  Plasmodium falci...
Q8I218    1243 ACVPPRREKFCVSLLAKEgifk--------nkgEDIRETFVKSAALETYFAWKRYNDDNkkaeee---lksgtiPENFKR 1311 Plasmodium falci...
Q8IAK3    1247 ACMPPRRQKLCVSGLTQGgki---------ttiEDIRTQFITCAAIETHFAWHKYKKDNvnaere---lnsgiiPHEFKR 1314 Plasmodium falci...
Q8I640    1285 ACMPPRRIKLCIYYLENH------TqkgnikkeFQLREAFIKCAGAEIFLLWQKYKTDNnsdtklqtqlesgqiPEEFKR 1358 Plasmodium falci...
XP_966305 1361 ACMPPRRQSLCIHNLKESnet---------gteQQLREAFINCAAIETFWLWYKYKKDKnvdaekk--leqgeiPSEFLR 1429
7JGG_A     155 ALERSFADIADIIRGTDLwkgt-----nsnLEQNLKQMFAKIRENdkvLQDkypkdqNYRKLREDWWNANRQKVWEVITC 229 
Q8IIZ4     973 QMFYTFGDYRDFLFGTDIsklnk---hteaVKTNIDRIFPPTERT---NDT----------IRKEFWEKNAESIWQGMLC 1036 Plasmodium falci...
Q8I098    1828 QMFYTFGDYRDLCLDTDIsskadtstgvgkVKINIDSVFQKIDIT---NVE----------QRKPWWGKNAEAIWDGMLC 1894 Plasmodium falci...
Q8IAK2    1363 SMFYTFGDYKDICLDTDIslkten-gditkAKSNIDRIIPKKSAK---NPD---------EERKIWWDGIKEDVWEGMLC 1429 Plasmodium falci...
Q8IEU9    1330 QMFYTYGDYRDFLFGTDIskglg---egtaLEKQINILFPNGVRK---IPN--------EKTREKWWTDHGPEIWKGMLC 1395 Plasmodium falci...
Q8I220     974 SMYFTYGDYRDICLNTDIsktvn---dvakAKDKIGKFFSKDGSK---SPS-------GTTTPQDWWQTYGKDIWKGMIC 1040 Plasmodium falci...
Q8I218    1312 QMYYTFADYRDIFFGTDItshd----hildVSKNAKNKLKEKNGE---QKSvi--iiDDEKLLADWWKEHGHEIWEGMLC 1382 Plasmodium falci...
Q8IAK3    1315 QMYYTFGDYRDIFFGTDIsthn----hipeVSQKVITILEKENLT---KSEvk--qkYKNELLDDWWNEHGKEIWDGMVC 1385 Plasmodium falci...
Q8I640    1359 QMFYTFGDFRDLCLGNDIgkad----ntkdISTTVNRILSVTNGE---TQT----------TAENWWEKNAESIWQGMLC 1421 Plasmodium falci...
XP_966305 1430 SMIYTFGDYRDLCLNTDIsakkd---pikiVKNNIQKVFNRNNGP---HKE------GDKEKRKKFWETNKNDIWQGMLC 1497
7JGG_A     230 GARS---NDlliKR--------------------------------GWRTsgksngdnklelcrkcghyeekvptkldyv 274 
Q8IIZ4    1037 ALSYn--SN---DKkmdpdvqkelnst-------ynydtiknnledFANR------------------------------ 1074 Plasmodium falci...
Q8I098    1895 ALSYn--TT---NKnmdynahtklnpt-------ygynaikseledFVNR------------------------------ 1932 Plasmodium falci...
Q8IAK2    1430 GLSHavsNN---DKatvqktlttktiyd----ydtvtfdgttkledFSKR------------------------------ 1472 Plasmodium falci...
Q8IEU9    1396 ALTNglsES---EKktkifddyshdkv-------nqskngnpsledFAKK------------------------------ 1435 Plasmodium falci...
Q8I220    1041 ALTHgvtNT---EKktkikndysydkv-------nqsqngnpsledFAKK------------------------------ 1080 Plasmodium falci...
Q8I218    1383 ALTHe-iDE---EEknkikstysydql-------kkttngttplekFAER------------------------------ 1421 Plasmodium falci...
Q8IAK3    1386 ALCYdtkTK---EFknevrtqltgpnskyqygtvsfgdkqntilskFAER------------------------------ 1432 Plasmodium falci...
Q8I640    1422 GLSHavsAR---DKetvqktltnnpsykyd-lvkfsgsdnpptlekFAQT------------------------------ 1467 Plasmodium falci...
XP_966305 1498 ALEKi--AN---NKktltetynyslv--------kfsgnnsttledFAKT------------------------------ 1534
7JGG_A     275 PQFLR 279 
Q8IIZ4    1075 PQFLR 1079 Plasmodium falciparum 3D7
Q8I098    1933 PQFLR 1937 Plasmodium falciparum 3D7
Q8IAK2    1473 PQFLR 1477 Plasmodium falciparum 3D7
Q8IEU9    1436 PQFFR 1440 Plasmodium falciparum 3D7
Q8I220    1081 PQFLR 1085 Plasmodium falciparum 3D7
Q8I218    1422 PQFLR 1426 Plasmodium falciparum 3D7
Q8IAK3    1433 PPFLR 1437 Plasmodium falciparum 3D7
Q8I640    1468 PQFLR 1472 Plasmodium falciparum 3D7
XP_966305 1535 PQFLR 1539
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