3AU2


Conserved Protein Domain Family
PolX

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COG1796: PolX 
DNA polymerase/3'-5' exonuclease PolX [Replication, recombination and repair]
Statistics
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PSSM-Id: 441401
Aligned: 226 rows
Threshold Bit Score: 463.509
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3AU2_A         1 M-----------RNQELARIFEEIGLMSEFLG-Dn---PFRVRAYHQAARTLYDLDTPIEEIAEKG---KeaLMELPGVG 62 
AFU60427      15 K-----------KNSDVAKVMRDLGFLTEVGE-DdpnaQFRARAYYRAADTIASLPEDVAVMYSRNgikG--LLEIPSIG 80 
WP_010876189   1 M-----------KNHLVAHILNRVADYMELAG-D----EFRTKAYRRAARTVEFLNEDIEEVAARG---R--LQELPGIG 59 
WP_012514481   1 Ma----------STKDIAKLFKEMALAAEFLG-En---KFRVLAYQKVADILFEIDKDIKSVDELKeylT--TNQIHGIG 64 
WP_012674658   1 Myl--------nINKEIAKIFRDMAHIYEFLDd-----KFRALAYQKAAQVLEDLPDDVRNYIALG---K--LSEIRGIG 62 
WP_012675702   1 My---------nINRDLANIFKKMAAIYEFLDd-----RFRAMAYQRAAHIIEDLPEDIRNYIVSG---K--LYMIRGIG 61 
WP_013537816   1 M-----------KNKELAQIFEKWADILEFMG-Dn---PYHVRAYRNAARLINDLSEDIEVLAREG---K--LSQLPGIG 60 
WP_014218550   1 MelitvskktekHNPELAAIFHQMASCYRYLGaKh---RFRVMAYDSANRTINNLKNDISEYAGKNd--G--LHELKGIG 73 
WP_075054954   1 M-----------KNGQVAKALRDIGFLTEVED-Aen-aQFKSRAYYRAADSIEALEQDVAGVYEKGginA--LLELPGIG 65 
WP_068550088   1 Mn----------RNKELARILNRIADFLELKG-El---VYKINAYRRAARAIESISEDIEEIYKRG---E--LYEIPGVG 61 
3AU2_A        63 PDLAEKILEFLRTGKVRKHEELSRKVPRGVLEVMEVPGVGPKTARLLYEGLGIDSLEKLKAALDRGDLTRLKGFGPKRAE 142
AFU60427      81 KAIAAKIEEYIKTGKVHTLEKMKAEIPINIDELYGLEGVGPKTIRALYDKLQVKNLADLEKAAREGRLRTVPGFTERKEQ 160
WP_010876189  60 RNIAGKIEEILSTGSLQLLERLSEEYPVDLDSLLSVEGVGPRTVKLLYEELGIKTLADLEEQARRHRIRRLRGMGEKREA 139
WP_012514481  65 ESSLEKIEEYLKTGRIKKHYEFLQKVPKELLDIMDAPGIGPKTLKTLYDVFGIKNKEELLKALDDPRIKTIKGFGPKKIE 144
WP_012674658  63 THTQEKIIEYIKTGKIQKYEELKKLVPPDFLELMDVPGFGPKTLKRIYQELGISTKEELIKALKDGRVAKLKGFGPKKVE 142
WP_012675702  62 PSIASKIEEYVKTGKIQKFEELKKQVPEDFIELIDLPGFGPKTLKKIHDELGISTKEELVKALKDGRVEKLEGFGPKKVE 141
WP_013537816  61 QRLQAKILEFLRTGKIEEFEKLKQQVPDTIFTLLDIPGVGPKTVKLLYEELGIRSIEDLKRAIERGELLKLPGFGPKRVE 140
WP_014218550  74 ESIGEKIIEYLHTGKINTFDQLKKKVPLGLLELMDINGLGPATVKTLHRRLHINNKEELIAAIEAGKLENLKGFASKKVE 153
WP_075054954  66 KAIAAKIEEYLKTGRIRHLDELKEKIPIDIGQLGAIEGVGPKTLKAIYEKLKVTDMAGLEKAALEGRLKTVPGITARKEQ 145
WP_068550088  62 ERIAKKIEEFIKTGTISKYEELRKEFPEELAQLLDVPYLGPKTLKLAYEKLGVKSLEDLKRVLEDGSLARLPGMGPKKVE 141
3AU2_A       143 RIREGLALAQAAGKRRPLGAVLSLARSLLEAIRA-LPGVERAELCGSARRYKDTVGDLDFLVASREG--ERAVEGFVRLp 219
AFU60427     161 DVLKKIEFFRTGRGRHIIGEVYPLIKQIEKSLLQ-VAGVKNAVAAGSVRRMKETIGDIDYLVAASDP--EPVMDFFTKMp 237
WP_010876189 140 MILRNIELARSRISRRPLAYVVPLASRIKAGLLE-LEGVQRVEVAGSIRRGRETVGDIDILVTATDP--EAVMDHFTSMd 216
WP_012514481 145 NIKRGIALFEQSKERMFITEAYSLAQDILSYMKG-CKEIINISVAGSLRRMKETIGDIDILVSTKKEdfPKVHEYFKAYk 223
WP_012674658 143 NMLKGLELYEKSKERLLLWEALNIANTIVEKLKT-LKEIKNIELAGSLRRKKETIGDIDILISCDDKdrEKVIDFFINLe 221
WP_012675702 142 NMLKGLQMYEISKRRIILWEALQISEYLKEKLKSgLKEIKKIEVAGSVRRRKETIGDIDILVTAEDKyrSKIMDFFTSIe 221
WP_013537816 141 KIKKGIELLEKSGGRILLGVAVFIADRIVNHLKE-HSAVERISVCGSTRRMKETVGDIDILASGKNN--LEIVEAFVNLp 217
WP_014218550 154 NIKRGLKLFKQAHSRMLLWDAQRTGEDILQQVLQ-LPGIKKAALAGSLRRKKETIGDIDIVATADKKdwKKIVTRFASLp 232
WP_075054954 146 DILKKIEFTKKNGGRSIIGEVWPLAKKIEARLKG-LEGVRHAALAGSARRMKETIGDLDYIVCASEP--ENVMDFFVKMp 222
WP_068550088 142 NIKKGLELYLKGSDRMLLGEALELAEYVIGQLKD---YCDRISYAGSLRRMKETIGDIDILAVGNKR---EIMDRFVSId 215
3AU2_A       220 qVKEVYAKGKERATVFLk---NGLQVDLRVVPPESYGAGLQYLTGSKAHSIRLRALAQEKGLKLSEYGVFR--GEKRIAG 294
AFU60427     238 eVQEVFGRGPAKAFVRLt---SGIDADLLVVPEESWGSALQYFTGSKEHSVELRKIALSKGLRLNEWGVFK--GEKRVAG 312
WP_010876189 217 eVEEVVVRGPRKSTVRLr---EGLDCDLRVFDDEVFGSALLYFTGSWEFNVELRRRAISSSMKLSEYGLFR--GDERVAG 291
WP_012514481 224 dMEQVIGSGETKTSILLk---NSKQVDLRVLKEEEWGSGLQYFTGSKEHNIKIRDIAKEKGYKISEYGIFEisSGKRLGG 300
WP_012674658 222 dVKEVLAKGDTKASVIIk--eKDRQVDLRVLKPDEWGSGLQYFTGSKEHNVHLRDYAKSIGLKISEYGVFDakTGEKIAG 299
WP_012675702 222 eVSEVLVKGPKKSSVIMkfegKERQVDLRIFNDDEWGAALQYFTGSKQHNVHLREIAKEKGLKINEYGVFDakTDKKIAG 301
WP_013537816 218 nVKEVLWKGPKKATVIVe---EGEQVDLRVIEPDSYGAALQYFTGSKAHNIHLRTICLKMGYKLNEYGLFK--GDKRIAG 292
WP_014218550 233 qTDRVLAKGDTRAAIVLk--gSGTQVDLRLVQAHEYGAALLYFTGSKEHNIALRALARAQGYKLNEYGVFDavTDRKLPG 310
WP_075054954 223 eVEEVKSRGPAKAFVRLa---GGIDCDLLAVPEESWGSALLYFTGNKEHNVELRRIAIARGLRLNEWGAFEn-NDRRVAG 298
WP_068550088 216 kVTEVIAKGETKSSVLIg----TRQVDLRVVEEDQWGAALQYFTGSKEHNVHLREIAKEKGLKINEYGVFKvaSGVKIAG 291
3AU2_A       295 ETEEEVYAALGLPWIPPPLREDQGEVEAALEGRLPKLLELPQVKGDLQVHSTYSDGQNTLEELWEAAKTMGYRYLAVTDH 374
AFU60427     313 AAEEEVYQALGLQWMPPEMRENAGEIELARQNRIPKLVEYGSLKGDLQVHSENSDGTATIEEMARGAKAFGLDYIAITDH 392
WP_010876189 292 RTEAGVLEALGLSYIEPELRENRGEVEAAARDELPELVTPLDIRGDLHMHSLFSDGIDSMEQMAEYASVLGREYIAITDH 371
WP_012514481 301 EKEEDIYKILDMVMPPPEIREDKGEIELAMQGIVPELVGYDDIKGDFHMHTTYSDGKASLRQMVQACYELGYRYIVISDH 380
WP_012674658 300 DTEESVYKAVGMQWIPPELREDRGEIEAALKNSLPKLVELSDIKGDFHCHSTWTDGFNTILEIGQYIKENFKYEYLVITD 379
WP_012675702 302 ETEESVYQSVGLKWIPPELREDRGEIEASMRDALPDLVELKDIKGDLHVHSTWSDGVVSIKEIIDFVKKKYRYDYIAITD 381
WP_013537816 293 RTEEEIYSALGMDTPPPEIREDTGEIEAAQEHRLPKLVGYNEIRGDLHLHSTWSDGASTIEDYVKRALEMGYSYIAISDH 372
WP_014218550 311 TTEEEIYRLFDLQFIPPELREAGREIETARKKHIPGLLQLKDMKGDLHLHSTWSDGADEIETIARYICKEFPAYEYIVIT 390
WP_075054954 299 ASEEEVYKALGLAWIAPEMRENAGEIDLAAKGRLPSLVEYGSLRGDLQVHSDNSDGTATMEEMALAAKEFGLDYIAITDH 378
WP_068550088 292 KTEEEVYAVLGLPYIPPELREDRGEIEAALEGRLPEIVPYEGIKGDFHVHSNWSDGGFSIEEIARAAKSVGLKFVAITDH 371
3AU2_A       375 SPAVRVAGGPSPEEALKRVGEIRRFNETHGPPYLLAGAEVDIHPDGTLDYPDWVLRELDLVLVSVHSRFNLPKADQTKRL 454
AFU60427     393 TKSLALAGGLDGQELLEQAQKIAELNDRLEGGFRVLASAEVNIMKDGSLDIADNVLDKLDIVGAAIHSHFNLPVEAQTER 472
WP_010876189 372 ARYIDDPDAYFRAAERIEEIDVLAGVEVSILHDGNLEVPDGALKNFDLVIASIHDPGNLTERLLAAMDHDPVSIIGHPTG 451
WP_012514481 381 TKSLRVAGGLDEEGFRNQWKEIEQVQKEYKDMTLLRGCEVDILEDGSLDLPDSFLEEFDYVIASIHSHMSPSTDNTKRVL 460
WP_012674658 380 HSKAVRVAHGLTEDDVLKQIEEIDKVNKIIGYPLLKKGIEVDILLDGSLDLSDEILSKLDWVVASIHTNFNRDNTDRIIK 459
WP_012675702 382 HSKSQRVAHGLDEGRLLEEINEIKLLNKMIGFDFVKTGIEVDILLDGSLDLPDDVLSKLDWVVASVHSHFNRDNTDRIIK 461
WP_013537816 373 SKSLRVAGGLTEEELLKRNYEIDKLNERLGGKITVLKGAEVDILPDGSLDYPDEILVQLDFVIAAVHSRFNQDNTERILK 452
WP_014218550 391 DHSPSERVAHGLQPADFTDLFREIERINKKLGKNLVKKGAEVDILANGSLDLPNELLQHLDWVVASIHSGFKKDNTERLL 470
WP_075054954 379 TKSLAMAGGLDEQELLDQAQKIAELNDRLDGIRVLSSAEVNIGKDGSLDIANNVLDKLDIVGAAIHSHFGLSMEEQTARL 458
WP_068550088 372 SKSVKIAHGLDEERLLKQIEEIDRLNKQLKGFKILKGIEVDILPDGSLDLSDEVLSKLDWVVASVHSRFNEDATERILSA 451
3AU2_A       455 LKALENPFVHVLAHPTARLLGRRAPIEADWEAVFQKAKEKGVAVEIDGYYDRMDLPDDLARMAYGMGLWISLSTDAHQTD 534
AFU60427     473 LTRAAKNPNVDILFHPTGRLINKRLGYPVDIEQVIEVAKDTGTVLEIDAHYDRLDLKDEYARMAVKKGVKLVVDSDAHHP 552
WP_010876189 452 RVLGSPEPVVDIERVIEGAAEAGVALEVNSNPLRIDLRDTHVKMAVDMGCKIAINSDAHSRGALENISWGVITARRGWAE 531
WP_012514481 461 KACHNKYVNQIGHPTGKNYGYRDGYILNMEEVIKAALDTNTALELNIPRADLSPDNIRLAVERGVIISIVTDSHSSSYLR 540
WP_012674658 460 AMENPYVNVIGHPTGRIFGTREGYQLSDEVFKVAKETGTALEINSQPLRMDLPDIMVKKAVDMGVKLVISSDSHSLSNFH 539
WP_012675702 462 AMENPYVNVIGHMTGRLIGLREGYPVDMNAVIKAAKETGTALEINAQPRRMDIDEIWIRKAVEEGVKLVISTDAHNLGNF 541
WP_013537816 453 AINNPYVNAIAHPTGRIIGQREGYPLDIEKVIKAAAETGTALEVNSYYNRLDLRDAHCRMAVKAGVTLVINTDSHHTDHM 532
WP_014218550 471 KACANKYVNCIGHPWGRLINRRDGYDVDWNKLFEILNKTGTAIEINAQPDRLDLPDYLVKEAVAAGVMIAIGTDAHALTQ 550
WP_075054954 459 VNAAKNPSVDIIFHPTGRLINRREGYPVDIARLTDVAKDTNTALEIDAHYNRLDLKDEYVRMAVRKGVKLTIDSDAHHPV 538
WP_068550088 452 MRNPYVTCIGHPSGRMLFQREGYPVDWERVFEEAARTGTCLEINAHQDRLDLTDVLARKAKEFGVKFAIGTDSHHIGQFW 531
3AU2_A       535 HLRFMELAVGTAQRAWIGPERVLNTLDYEDLLSW 568
AFU60427     553 IHYAFLMFGVAQARRGWATPADVLNTLPADRLLK 586
WP_010876189 532 AGDVLNTMGLRGFMKWLRR--------------- 550
WP_012514481 541 FMKVGVGLARRGWALKERVLNTKPLEEVRAFVRK 574
WP_012674658 540 YIQLGVYIARRGWAKKEDVINTLSWKEVEKFVKD 573
WP_012675702 542 AFMEIGVYIARRGWAEKKDILNTGSWKDIQRFIT 575
WP_013537816 533 WMMKLGVGTARRGWVEGRSVLNTRPLSELKAFVA 566
WP_014218550 551 FDFMQLGVSVARRGWCEKANILNTHSWKRMEQFR 584
WP_075054954 539 HYAFLQFGIGQARRGWATAADVLNTMPADRLLKA 572
WP_068550088 532 MLRLGVGVARRGWLTVDDVLNYWDLRKIRAFINK 565
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