4IQD,3B8I


Conserved Protein Domain Family
PrpB

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COG2513: PrpB 
2-Methylisocitrate lyase and related enzymes, PEP mutase family [Carbohydrate transport and metabolism]
Statistics
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PSSM-Id: 442003
Aligned: 445 rows
Threshold Bit Score: 152.21
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4IQD_A        16 ELANRFRALVEANEILQIPGAHDAXAALVARNTGFLALYLSGAAYTASk-GLPDL-GIVTSTEVAERARDLVRATDLPVL 93 
WP_017989680   7 REKVKFRDLVSR-KQVFTPCVWDCYSAKAAEMAGFEAILLSGASLGFSmsGVPDL-GLHNQEELVYATDRIADYSPLPLV 84 
NP_711597      7 KKAEMFRSLHER-GTFIMPNAWDAGSARMLVGSGFSAIGTTSAGIAFAa-GLPDH-QILDRDVMLEYVRNIVASVDVPVS 83 
WP_013419043  25 EKVRRFRKRLQAREAFILPEVWDVISARVIGDAGFDIVGISPVSVAWSc-GLLPS-DRVPLDTLVETAKSVAMNFSVPVN 102
WP_013645436   1 MKTKILKNLLNSPETLVMPDAYDPISAKLIENAGFKAVQCSGYSFSIAa-GYNNE-IDVTLDENLEWTRRIVESVDVPVM 78 
WP_014088482   5 HKARLFKELHRRSGTFLMPNAWDAGSARLLSSLGFPAIATTSAGIAFSl-GLPDYaGAVSREAMLERVGQIAAAVDLPVS 83 
WP_088874532   7 EKRAAFRALHQD-GCFLLPNPWDVGSARMLQHLGFQALATTSSGYAWTq-GRPDY--GVTRDDVLAHLRALVPATDLPVN 82 
WP_068032407  10 DKRKTFRELHRS-GCFVIPNPWNVGSARYLQGLGFKALATTSAGHAHAm-GYPDG--AQSRDEVLAHYKELAAATDVPLN 85 
WP_075284142   6 KRRAAFKALHEKGRAFLMPNPFDIGTARILDGLRFDAMATSSAGYAWTq-GVKDAeGLITRDDALGHAADIIAATSVPVN 84 
WP_077296827  10 RHGQQLHALHRQAQPLLMPNAWDAGSAMLLAAQGFAAIGTTSAGIAFSl-GQPDQeSAVPFARMLARIAEIAAAVEVPVS 88 
4IQD_A        94 VDIDTGFGG-VLNVARTAVEXVEAKVAAVQIEDQQLPK-------------KCGHLNG---KKLVTTEELVQKIKAIKEV 156
WP_017989680  85 IDADDGFGD-VVQTFRTCYRLAKAGAGAILIEDTPNERgyarfgrameaatLAGKVDGnvpHEVVSQELWLAKIKASIEA 163
NP_711597     84 ADLESGYGIePDKVAETVRRAISIGVVGCNIEDLSGDN-------------SS---------PLLNAELAAERIHFARQE 141
WP_013419043 103 ADLEGVIGRsMEEIGRAVGAVISAGCVGVTIGDGGRGG-------------QH---------GMASMHDMTAAIKAAKAA 160
WP_013645436  79 ADAEDGYGG-PEVVMETVKKFLQTGVGGLNLEDQIPSR-------------KNGI-------SVVDADLMTEKIRVAKET 137
WP_014088482  84 ADLEAGYGVePEQVGDTIRQAIAVGAVGGNVEDFTGEP-------------SA---------PLFDLALAAERIRAAREA 141
WP_088874532  83 ADYESGFAHeISDLAANVRMAVEAGVAGLSIEDIRADG-------------QP---------GHYDTATAVERIRAARKA 140
WP_068032407  86 ADFENGFADdPDTVAENVTRCIATGVAGLSIEDSPQHG-------------QF---------PLYDFDLALARGKAARAA 143
WP_075284142  85 GDLENGFGDsPDDVVATVKGAIEVGLAGCSIEDYTTDP-------------KH---------PYYDLELAVERIKAAVDA 142
WP_077296827  89 ADLQSGYGDtPAAVADSLSQLMAVGAVGANLEDARPDQ-------------A----------GLFSRADACARIAAARQA 145
4IQD_A       157 Ap-----SLYIVARTDARGV-----EG----LDEAIERANAYVKAGADAIFPEALQSEEEFRLFNSKV-NA-PLLANXTE 220
WP_017989680 164 Cqg---sDCVVIARTESKLE-----KG----LDDAIERCVRAAALGAEMTYVHGLRTLEECRKVAKEL-PGwKMFGDVAT 230
NP_711597    142 Anaa-gfAFTLTARTDTFLTn---hPNa---LDETIRRADMYRKAGADCLFIPGVNDLETIGNLVRSI-DC-PLNVVV-- 210
WP_013419043 161 Alet-rvPAVVTARTEAFLLe----PPpyspFETAVERAEAYFAAGADCIAVPGVQHIQIIERLSAHV-DG-PLQITV-- 231
WP_013645436 138 AeieakpDFIINGRTDALRStedryEG----LEIAIDRANEYIEAGADLTFITYVATLDEVKQIKKEV-KG-PVTIAA-- 209
WP_014088482 142 Adas-glPFTLTARTDCYLAg---vDDp---FAAAVERANRYREAGADCLFVPGVSDPEVIAALVQAI-DG-PLTVVM-- 210
WP_088874532 141 Idqv-daQAVLVARTEILLSd---pSR----VAEAIDKMVALADAGADCLYAPGLVEKADVMALVRAVaPK-PVNLLV-- 209
WP_068032407 144 Idka-ggDVVFTARTEGFIRg---rPD----LDETIRRLKAFADAGADCLYSPGIKTREQIEATVKAVgGK-PINFLN-- 212
WP_075284142 143 Knrl-apDFVLTARSEGPVQt---qHE----LDETIKRLNAFAEAGADCVYAPELKDKEQIAAVLAAV-KA-PMNVLA-- 210
WP_077296827 146 Adas-gvPFVLTARCDAFLHn---vADp---LSEAIARCQAYRAAGADCLFVPGPADAPTLAALVQGV-DG-PLSVVM-- 214
4IQD_A       221 FGK--TPYYSAEEFANXGFQXVIYPVTSLRVAAKAYENVFTLIKETGSQkDALSn----X-QTRSELYETISYHDFEELD 293
WP_017989680 231 VNG--VPFVRLEEIEALGFNLVTM-HYLEKGSMYGMMDYGRHVFKDRSTryaDEhsmggM-TPAEQKASLERDSGWLDAE 306
NP_711597    211 GLG--KNNFTAADLLSLGVRRISIGGSLARACFYLIHQAALEMFNRGTFnFTETq----L--THKELCDFFAAF-----E 277
WP_013419043 232 Gl---TPAPDLKALNAAGASSVALGTALMRSLLGNLRLKAEEIFAFGQFnNLDKa----I--PADALNDLLR-------- 294
WP_013645436 210 GQPynINEFTINDLKTYNVERVSLPTLLIFTSLYGINLALEHLKKDSLSeMFEEe----LvYPADGLNKIL--------- 276
WP_014088482 211 GLS--GSALSVSQLAALGVRRITIGGSLARATYGLIRQAAVEMKEQGSFsFVDRq----I--PDGELCRFFAAF-----P 277
WP_088874532 210 MRP----GPSLAEIADWGVRRVSVGGGLARAAWGGFLRAAEGLQ-AGSFdGLAAg----A--SGKQLNEIFANF-----T 273
WP_068032407 213 SGA---FGFTVSDLAGMGVRRISVGGTLSRVAMDAFVKSAKAIATDGKFdSFAGt----I--SNQELNAFFSND-----R 278
WP_075284142 211 GRK--NFHLTRKELGDMGVTRVSIGAGLARLAYRAFIAAAEDMKDGGTFgCFDRt----E--TMPEGIPDFESF-----M 277
WP_077296827 215 GLA--GSPLTVAQLAALGVRRISIGGSLARACLGLVRRAAEEMQQHGSFaYASQq----I--PDGELSAFFADR-----R 281
4IQD_A       294 TGIAK 298
WP_017989680 307 DRWKA 311
NP_711597    278 TK-EK 281
WP_013419043     -----    
WP_013645436     -----    
WP_014088482 278 PI--- 279
WP_088874532     -----    
WP_068032407 279 KT-WS 282
WP_075284142 278 KT-RP 281
WP_077296827 282 RAVEK 286
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