Conserved Protein Domain Family
COG2509

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COG2509: COG2509 
FAD-dependent dehydrogenase [General function prediction only]
Statistics
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PSSM-Id: 441999
Aligned: 411 rows
Threshold Bit Score: 227.303
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_045532500   1 Mirlselkldlsalplpvegdadsvhplsalrslaaqtlgvpeaqianvhvhkrsfdarsvqlrvvfvidlqltdtelea 80 
NP_833487      1 M------------------------------------------------------------------------------- 1  
WP_012543959     --------------------------------------------------------------------------------    
YP_003317015     --------------------------------------------------------------------------------    
WP_013047507     --------------------------------------------------------------------------------    
WP_014162469     --------------------------------------------------------------------------------    
WP_014807579   1 M------------------------------------------------------------------------------- 1  
WP_014643610   1 M------------------------------------------------------------------------------- 1  
WP_015326183   1 M------------------------------------------------------------------------------- 1  
WP_066743321   1 M------------------------------------------------------------------------------- 1  
WP_045532500  81 ellqrhagrshiqpspdmrwhapasapaDWplasEQRPVVLGFGPCGLFAALALAQ--MGLKPLVLERGRPVRQRTADTW 158
NP_833487      2 -----------------------------------YDVTIIGAGVSSIFMAYSLAK--SNKKVLILDKGKALEDRHCPLD 44 
WP_012543959   1 ----------------------------------MSKVVIIGAGPAGIFCGLRLSEvlSGEDITIIEKGKPIDKRHCPLL 46 
YP_003317015   1 ----------------------------------MYDVIMVGAGPAGILAARELVK--AGKRVAVVDKGRDIGSRHCPLK 44 
WP_013047507   1 -----------------------------M----KYDVIIVGSGPAGVFAAMELVK--SDKKVLILDKGKLIKERKCPIL 45 
WP_014162469   1 ----------------------------------MYDAVIVGAGPAGLFAAREMIR--GGLKVAIVDKGRNIQNRTCPMK 44 
WP_014807579   2 ----------------------------AN----RYDVIVVGAGPAGLFAALELSK--ANLSVLLVDKGKTLEERKCPLK 47 
WP_014643610   2 -----------------------------------EDIIIIGAGVSSIFFAHKLVQenNNLSIRIIDKGKPLMERKCGLD 46 
WP_015326183   2 -----------------------------------KRITIVGAGVSGLFLAYTLLQkdRKLQIQIIDQGRPLKKRSCPLQ 46 
WP_066743321   2 ----------------------------TK----SYDAIIVGAGPAGLFAAMELAN--KGKKVVVIDKGRSIESRKCPMK 47 
WP_045532500 159 GLw-RK-QQLQPeSNVQFGEGGAGLFSDGKLYSQIK-----------DP-RWLGRKVLQEFVAAGAPPD----------- 213
NP_833487     45 EG--KVc-NCTT-CDKYFGFGGLGK-SEGKFNYTNGfggelekkvgkEGfLQLMAEVDEILCQFGGSSVskystenssl- 118
WP_012543959  47 LN--GKcVSCEP-CSMISGWGGAGAYSDGKLNITGEiggflneilgeRRfGSFVPEVLKYFYDHGAPKDldnvaerpevd 123
YP_003317015  45 EGkvNRcVQCNP-CNVVCGWGGAGAYSDGKLTLTPEfggnlesycgrEElVRLIGQVDRVYVEHGASQElfspdsnlams 123
WP_013047507  46 EGlsPVcVNCNS-CNIVSGWGGAGTASDGKLTLTTGfggnleecigeDAlENMIRYVDDTFVSFGADKKyyeptgeivkd 124
WP_014162469  45 DGrsDKcLHCKP-CNIICGWGGAGAFSDGKLTLTPEfggnldkyigrAAlISLIDEADKEYLKHGASPQvfepdpafard 123
WP_014807579  48 MGlvPTcAHCNS-CSLMCGWGGAGAFSDGKLTLTPHfggnlekyvgkEKlLALLDEVDSIWMEHGANSAplfepdpefas 126
WP_014643610  47 EGl--ScTCGED-CNKYIGYAGLGK-SEGKFNYTNDfggdlgrkigeERtLELMKEVDRTLQRFGAESVglystknell- 121
WP_015326183  47 EEt-KQcVSCNK-CDQLSGLGGVMAKSEGKFNYTTDfggklatklntDTaFKLQNKVDQILYSLGTDKTthystknpkl- 123
WP_066743321  48 LGs-QEcVQCRP-CNVVCGWGGAGAFSDGKLTLTPEfggnleeycgrEKlLSLIAEADEMYLRHGASKTlfepsgdlakr 125
WP_045532500 214 ------------ILYQAHPHIGTFRLVKVVQALREQIIALGGEIRFEQRVSSLLLEpceqtvseglqtaaqpdsqpalha 281
NP_833487    119 --tkraeacglqMLTTEVRHLGTTLSSNIFQQLYEFLL-TKIKIQFHIDVQHILKQ------------------------ 171
WP_012543959 124 dwrkrarllgmkLITFPIIHLGTDKTKEVLANMYDTLRNRGVNIIFDTEVEDILTE------------------------ 179
YP_003317015 124 -vmdrarrsglqVIPATIRHMGTDRSKDILSSIMREL-EGGADIILGKAVSEVLVE------------------------ 177
WP_013047507 125 -tiqkaasrgikIIPARIRHIGTDASRMVLNNMYEEL-KEKCDILMNTEVKEVVVH------------------------ 178
WP_014162469 124 -vavrassaglrIIPARIRHMGTDRSKDILKSMYDEI-ASGCDVYMNQAVEKVLVV------------------------ 177
WP_014807579 127 svikrgrvaglqVIPAKIRHIGTDRTKEVLRNIYHKL-RDKVDILMNTEVKSILSE------------------------ 181
WP_014643610 122 --aakaeklgleVLSAQVRHLGTQVAVEVFQELYETMK-KHIHFTFETNVISVQSK------------------------ 174
WP_015326183 124 --iqeakehgleVLTTTVRHLGTDLTYKITTNLYHRLK-DRIDFRFNTEVTSIDKQ------------------------ 176
WP_066743321 126 -viaralqagldIIPATIRHMGTDRSKYILGAMYETM-KDNCDVMTGTPVDRVLLKa----------------------- 180
WP_045532500 282 PEqqalRLRAVRVLDqasgtEYVWPCERLVLALGHSARDTFAML-HDAGVALQAKPFSIGVRIEHPQGLIDRARWGrhtg 360
NP_833487    172 ED-----HFTIDTNQ-----G-TVQTKQLVFATGRSGADWLKEMcSSLNISQEQTRVDLGIRVEMKEHQLRSILKD---- 236
WP_012543959 180 DK----KVVGVRTSS-----GDFLKADYVVVAVGRSGADDLTRWvNGLGLHFGTNPVDLGVRVEVPAEVLLPMTDV---- 246
YP_003317015 178 DG----QVLGIRLSD-----GTELRSRMVMLAPGREGAPWMEEAvRRLGLEIESLPVDIGVRVEIPAAWAKEITDQ---- 244
WP_013047507 179 SG----VVEGVVLKD-----GQEINSEYVILAPGREGSSWLEGIvNKYNLPIASMPVDIGVRVEVSDSICQDLTKH---- 245
WP_014162469 178 DN----EAKGVILRD-----GTTIEAKVVLLAPGREGAFWMEEVvKELGIQIKSLPVDIGVRVEIPSEWAEMLTEQ---- 244
WP_014807579 182 DG----KVKGVELAS-----GERLDAEYVLLAPGREGAPWMERTsKELGLSVDSLPVDVGVRVEIPAELAEELTEQ---- 248
WP_014643610 175 AH-----SFLIETDK-----G-NFHSKQLVIGTGKSGGKWLEKQmKDLGLKTGETRLDLGLRIEMKEDQLDSILKE---- 239
WP_015326183 177 N------RFYLQTNQ-----G-IYKTDQLVLATGLTSNNLLGSFpE---VTTFNTRVDLGIRVEMKQKQLASILQD---- 237
WP_066743321 181 DG----SVAGVALEN-----GEELFSDCVLLAPGREGAAWMERTvHALGLEIESLPVDIGVRVEIPAAWAEDITDQ---- 247
WP_045532500 361 hpllgAADYKLVHHAAN-GRAVYSFCMCPGGTVVAA--TSEa-GRVVTNGMSQY--SRQERNANAGLVVAIEPRD-Fpld 433
NP_833487    237 -----TFETKLSYQGE--HFTATTYCMNPKGRIIRK--YEE--GLVMPDGQNFReqGTGTSNLNFTLFIPSYF-PtL--- 301
WP_012543959 247 -----LYEVKLEYYSKAfEDKVRTFCMNPGGEVVKE--HLD--DVITVNGHSYK--EKFLPNTNFAVLVSTYFTEpF--- 312
YP_003317015 245 -----FYEIKAILDTPTfDDKVRTFCMCPNGEVTTEyqTHH--GILTVNGHSNRdeDKKTENTNFAILVSTQFTKpF--- 314
WP_013047507 246 -----FYEVKCLYNTPTfDDRCRTFCMNPSGFVVHE--YNKahDLVTVNGHSLK--NVKSKNTNFAILVTKNFTQpF--- 313
WP_014162469 245 -----FYEVKAILDTPTfDDQVRTFCMCPHGEVTTEylEQH--GILTVNGHSNKngEGKTENTNFAILVSTEFTSpF--- 314
WP_014807579 249 -----FYEVKAIYNSPTfDDQVRTFCMCPYGEVVTEfqSDG--GVVTVNGHSYR--DKKTDNTNFAILVSTDFTEpF--- 316
WP_014643610 240 -----TFETKLRCRGE--GYEATTYCMNPRGRIIRK--YQN--GLVMPDGQNKNeeKTESGNLNFTLFVPRYL-SsY--- 304
WP_015326183 238 -----NFETKLRYQGT--DFTATTYCMNPGGQVVRK--YHQ--GLVMADGQNYAegTAATNKLNFTLFVPRYF-PtS--- 302
WP_066743321 248 -----FYEIKAILDTPTfDDRVRTFCMCPHGEVTTEfqSHH--NILTVNGHSNRenDKKTGNTNFAILVSTKFTKpF--- 317
WP_045532500 434 fpaataaweaafgpergrtyaqqaqalaergqvhpLAGVVLQRDLEARAFVAGGSnyCAPGQRVGDLLAQRASSA--FG- 510
NP_833487    302 -----------------------------------KEANVYASSIIKGINQ-GRD--RIVIQRLEDLLKKQPTAEnsMEh 343
WP_012543959 313 -----------------------------------KDPVAYGKHVAKLANLL-SD--GIIVQRFGDLVNGHRSTPerIKr 354
YP_003317015 315 -----------------------------------KDPNGYGSHIARLANML-GG--TVLVQRLGDLKRGRRSTHdrIAr 356
WP_013047507 314 -----------------------------------NDPIGYATHIAKLANMLAGG--GILLQRLGDLRDGRRSTEarITr 356
WP_014162469 315 -----------------------------------KDPNGYGSYIARLANLL-GG--GVLVQRLGDLKHGRRSTPdrIAr 356
WP_014807579 317 -----------------------------------HDPNGYGVHIARLANML-GG--SVLVQRLGDLKLGRRSTRsrIEr 358
WP_014643610 305 -----------------------------------DKAMQTAQCIIGGINQ-DNE--RIITQRLGDFYANRPSSE--LSs 344
WP_015326183 303 -----------------------------------KQARDYAANIIGRINQ-NRE--RIIVQRWGDLKQKLATTEkrLVa 344
WP_066743321 318 -----------------------------------KDPIGYGSHIARLANML-GG--GILVQRLGDLRKGRRSTHerIEr 359
WP_045532500 511 -SVQPSYQpGVHPTDLAAVLPDYALQALREALPAFGKKIRGFDLPDAVLTGVETRTSSPlRIPRGDNFQSlNVHGLYPAG 589
NP_833487    344 sRIQPTLQ--GDYGDLNQEIPQLYIEGLKEFLLRLEQFIQEPIDQHTLLYGIDGKFYAP-TIKINNHFET-SIHGLFLIG 419
WP_012543959 355 sIVKPSLE-DSIPGDLNAVLPRRHLESIIEFLQVLDQFAPGVGSRDTLLYGVEVKFYSM-RPEISNVLES-EISNLFMAG 431
YP_003317015 357 gLVRPTLK-TAEPGDLSFVLPYRHLKGIMEMIEALDSLMPGINGNHTLLYGVEVKFYSL-KLALSKDLET-NIRGLYAAG 433
WP_013047507 357 gMVKPTAQ--AQPGDLSLVLPHRFLIDVVEFIEALNIIMPGINMNDTLLYGVEIKLYSL-RLELKETLETpAIRNLYMAG 433
WP_014162469 357 gLVRPTLA-SAEPGDLSFVLPYRHLTDILEMIQALDSIIPGINGKHTLLYGVEVKFYSL-KLELDQDLMT-SIPGLYACG 433
WP_014807579 359 gLVKPTLV-EAEPGDLSFALPYRHLKDILEMLEALESIIPHVNDKYTLLYGIEVKFYSL-KLALDSKLKT-SVKGLYAAG 435
WP_014643610 345 nLIRPSLE--AEAGNLVDEIPGLYLRAVLEFMEKLENLIEKPIHPDTLVYGMDAKFYEP-QINTTKDFET-EIEGLFLIG 420
WP_015326183 345 nSITPSLQ--AEPTNLYKEIPKLYLTAIRKFFQALEKLINQPIAANTLLYGLDAKFYQP-EIKLDKNFQT-QIENLYLIG 420
WP_066743321 360 gLVTPTLT-SAEPGDLACVLPYRHLVGITEMLSALDHIIPGINGSHTLLYGVEVKFYSL-KVALDKGLQT-SIKGLYAAG 436
WP_045532500 590 EGAGYAGGILSAAVDGIRVAEALACAALG 618
NP_833487    420 DCSGVTHSLSQAAASGLYVGKYLSDi--- 445
WP_012543959 432 DGAGITRGLFQAAMAGLVVADTIKERCM- 459
YP_003317015 434 DGAGVTRGVIQASASGIWAARAMLRKL-- 460
WP_013047507 434 DGAGVSRGIIQAASSGVVAARSILYQG-- 460
WP_014162469 434 DGAGVTRGVIQASASGIVAGRAIVNRLK- 461
WP_014807579 436 DGAGVTRGVIQASASGLVSARSIIEEINK 464
WP_014643610 421 DCSGVTHSLSQAAASGLYVADRILQKNKG 449
WP_015326183 421 DASGVSWSLAQAAASGIYLGNKLGC---- 445
WP_066743321 437 DGAGVTRGVIQASASGLWAARSILGK--- 462
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