3G5O,3D55,2A6Q,6L8E


Conserved Protein Domain Family
PhdYeFM_antitox
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pfam02604: PhdYeFM_antitox 
Antitoxin Phd_YefM, type II toxin-antitoxin system
Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.
Links
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Statistics
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PSSM-Id: 460615
Aligned: 71 rows
Threshold Bit Score: 40.3183
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3G5O_D          8 MRILPISTIKGKLNEFVDAVSSTQDqITITKNGAPAAVLVGADEWESLQE---TLYWLAQPGIRESIAE 73  Mycobacterium tuberculosi...
Q82VL3          3 ITTLSSRELNQDIGRAKRAARNGP--VIITDRGKPVHVLLSYDEYQRIIGq--QENIVDQLGLPSGIED 67  Nitrosomonas europaea
jgi:Pnap_1822   1 MHTWQLQEAKSRFSELVDLTLSEGP-QLVTRRGQDAVVIVSAKDYRRMSGg--APSLLATLLNAPRGES 66 
WP_012205786    1 MKSWPVQDAQDHFNELLEACLTDGP-QVLTRRGADTAVLVPMQEWRRLHPaaePASLKELLLSEVGRAD 68  Delftia
Q8Y121          1 MQSWQMQAAKARFSDVVKRAADDGP-QEITVHGRPVAVVISRALFDRLSGs--GESLVSFMRQSPLADQ 66  Ralstonia solanacearum
Q7NI03          2 QSTWQLQEAKNQFSKVVDLAVTVGP-QIVTRHGEPVAVILSVAQYRKLTVp--RQSLVDFLRSSPLVGA 67  Gloeobacter violaceus
jgi:Gura_0714  12 EREWQLQEAKNRLSQVVDSALHDGP-QTITLRGKPAAVLVSFEEFKKLTQp--RSTLSQFFRQSPLHDT 77 
Q1QFA2         11 SNIWTLADAEVRFSEIIDRAQTRP--QVITRRGHPCAVLVSAEEWARRTAr--KGTLADFLLASPLRQD 75  Nitrobacter hamburgensis X14
Q1QFA3          2 SSTVTAAEVSKNFGAYQDAAVREP--VVITKNGRPRTVLMAYEDFVRLSKr--DRRVQRTIDLSEAEIA 66  Nitrobacter hamburgensis X14
Q02AM0          9 TIVVSALQARSNFGKLLRRVEDEGRsLVIEKRGTPKAVLLSIRDYVRLAAp--EPDVLKLIGEESQRKG 75  Candidatus Solibacter usi...
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