Conserved Protein Domain Family
COG7

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pfam10191: COG7 
Golgi complex component 7 (COG7)
COG7 is a component of the conserved oligomeric Golgi complex which is required for normal Golgi morphology and localization. Mutation in COG7 causes a congenital disorder of glycosylation.
Statistics
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PSSM-Id: 431125
Aligned: 4 rows
Threshold Bit Score: 1000.96
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q3T1G7     2 DFSKFLADDFDVKDWINAAFRAGPKDGAAGKADG--HAATLVMKLQLFIQEVNHAVEETSLQALQNMPKVLRDVEALKQE 79  Norway rat
Q7QA49     1 DVSAFSGDDFDVSSWINASYERSQKTATGSVGKEa-FVSSLVSKMQLYVQQINVALEQTGGQVLKNIPKVISDANMLQIE 79  Anopheles gambiae s...
EDW39280   2 DVSALSEATFSPADWINANYKKYIEENGSKDGDAtsFIQSYVAKLQLYVQQVNYAVEESSRQVVSSMPRIAKESTTLHSD 81 
Q9FGN0     4 DLGPFSDEKFDAKRWVNSSCQARHPQDSLEKH-----LVDLEMKLQIASEEIGASLEEQSGGALLRVPRATRDVLRLRDD 78  thale cress
Q3T1G7    80 ASFLKEQMILVKEDIKKFEQDTSQSMQVLVEIDQVKSRMQLAAESLQEADKWSTLSADIEETFKTQDIAVISAKLTGMQS 159 Norway rat
Q7QA49    80 SGLLKQRMNQVQREIAHLQTETGDCMVSLERLDDIKQRLQSSKQCLQEADGWGKLAGELDDLLEKSDIDASSGKLLSLQK 159 Anopheles gambiae s...
EDW39280  82 VSQLQEKMSAMRQEVAAVQNETGECMATLERLNTLQTKLQAAKESLQESDGWGNLLAELEDGFERNDLKGVCEKLIALQK 161
Q9FGN0    79 AVSLRGSVAGILQKLKKAEGSSADCIAALARVDNVKQRMEAAYKTLQDAAGLTQLSSTVEDVFASGDLPRAAETLASMRN 158 thale cress
Q3T1G7   160 SLMMLVDTPDYSEKCVHLEALKNRLEALASPQIVAAFTSQSVDQSKVFVKVFTEIDRMPQLLAYYYKCHKVQLLATWQEL 239 Norway rat
Q7QA49   160 SLAAQVGLHGHSERENLVEYFKNRLEALVSPSVVVALRSMDTAACRRYVGIFEGIGRLAQLKQYYRTVLKTFVQEQWSSA 239 Anopheles gambiae s...
EDW39280 162 SLHAQEQLPGHAERLTQVEDFKNRLEALASPSVVQCFAESNLEQAQHYVQIFASIQRLPQLQQYYRAVQKNLWQQQWKQT 241
Q9FGN0   159 CLSAVGEVAEFANVRKQLEVLEDRLEAMVQPRLTDALTYHKVDVAQDLRVILIRIGRFKSLELQYSKVRLKPIKQLWEDF 238 thale cress
Q3T1G7   240 CQRDl---------------------------PLDRQLTGLYHALLGAWHTQTQWATQVFKNpYE-VVTVLLIQTLGALV 291 Norway rat
Q7QA49   240 IEGSe--------------------------sGGSDVLKEFYDHLVELLKSHLRWSCQCFGE-AT-DCVLAVADALENLD 291 Anopheles gambiae s...
EDW39280 242 LELQgtet---------------------qpqQQQQFLTLYYDQLLEHCQRQVKWCSNLFSEeST-QPFLVIAELLPALQ 299
Q9FGN0   239 DTKQranklanersesqrlssgdefqstssqtSFASWLTSFYDELLLYLEQEWKWCMVAFPDdYMtLVPKLLVETMGVLG 318 thale cress
Q3T1G7   292 PSLPMCLSEAVERAGPEl------------------------eLTRLLEFYDTTAHFAKGLEMALLPHLQD----HNLVK 343 Norway rat
Q7QA49   292 PTRESVVRSALKRATDK--------------------------FWTLTQFSKVNVSMGSLIEGWVRGGPQQdircDDETT 345 Anopheles gambiae s...
EDW39280 300 PTRDAHILQLLKTSNER--------------------------LELLGLFSQVNHSFVLHLNSLLEQSHITl--sDELHR 351
Q9FGN0   319 ASFVSRLNLATGDAVPEtkalakgvmdllsgdlpkginiqtkhLEALIELHNVTGSFARNIQHLFAE--------SELRI 390 thale cress
Q3T1G7   344 VVELVDAVYGPYKPYQLKYGDLEESNLLIQISAVPLEHG----------EVIDCVQELSQSVHKLFGLASAAVDRCAKFT 413 Norway rat
Q7QA49   346 IDRLANSLFVFFGIFLKEYPTLENSQLEASLQGLTIVGT----------APADSVHNLESANAKIIRWALEAVTRCQDIT 415 Anopheles gambiae s...
EDW39280 352 Q--LGEAVFEYFHKFIQQYPRLEETQLSTQVDRLLSNQS----------TPSDAVRHLEESTRKLYEWLKEACERCSAIT 419
Q9FGN0   391 LIDTLKAVYSPFESFKQKYGKMERAILSSEIAVVDLRGAvtrgvgaqgiELSETVRRMEESIPQVVVLLEAAVERCIGFT 470 thale cress
Q3T1G7   414 NGLGTCGLLTALKSLFTKYVSHFTNALQSIRKKCKLDDippns-------------------lfqeDWTAFQNSVRIIAT 474 Norway rat
Q7QA49   416 QNCALLSLGSVLQNYLLTYLDQYNKVQKQLAASQPSQT----------------------------DWNLLQLSVVLLQY 467 Anopheles gambiae s...
EDW39280 420 SDLALCKLITLLNGIFKRQLENFGRIQRQLGLSLGSSSyaa----------------------qseNWSLLQYTMSQLQC 477
Q9FGN0   471 GGSEADELILALDDIMLQYISMLQETLKSLRVVCGVDGtgdgvgskkdasaekressrkmdltsneEWSIVQGALQILTV 550 thale cress
Q3T1G7   475 CGELLRQCGDFEQQLANRILSTAGKYlsdsysprslagfqdsiltdKKSPAKNPWqEYNYLQKDNPAEYANLMEILYTLK 554 Norway rat
Q7QA49   468 LGSFRQAAYELEQTFLQQVLTKHSQL--------------------TAGSARARF-EYRLNTKGEFNELHKLATTFQQPS 526 Anopheles gambiae s...
EDW39280 478 LADFQVQLHQFEHDLHARMATLAAKL--------------------TKQSSRGNItIFQTCDHAARTQLLNAIADYQQKK 537
Q9FGN0   551 ADCLTSRSSVFEASLRATLARLNSSLsislfgtnldhnlshlkseqTAGDLSMAGrASMDVAAIRLVDVPEKAHKLLNLL 630 thale cress
Q3T1G7   555 EKG-SSNhnLLSVSRTALTRLNQQAHQLAFDSVFLRIKQQLLLV-SRMDSWNTAGIGETLTDDLPAFSLTPLEYISNIGQ 632 Norway rat
Q7QA49   527 SES-GRE--YFSEFHQRMKRTCEDIHDTMLQIAFSPITKHFKQIePAATGPTGAAGGTTAMDTLPDYSYAPQEYITLISQ 603 Anopheles gambiae s...
EDW39280 538 AEA-TESlgIFPQIYAALKLQFSETHDITLNILLQPIETHLAHIrPAAETHPSTGI------DMPSFSFAPQESITQIGQ 610
Q9FGN0   631 EQSkDPRfhALPLASQRVAAFADTVNELVYDVLISKVRQRLGEV-SRLPIWSS--VEEQTAFPLPNFSSYPQSYVTSVGE 707 thale cress
Q3T1G7   633 YIMSLPLNLEPFVTQEDSALELALHAGKLPFPPEQgeelpeldNMADNWLGSIARATMQTYCDGILQIPAVTPHSTKQLA 712 Norway rat
Q7QA49   604 YLLTLPQHLEPLLLSPAAALKAVLEVADHRYASNR--------PCADVFLALVVEESEALYVEQIENICSLSVSGAKQLA 675 Anopheles gambiae s...
EDW39280 611 YLLTLPQHLEPLLLAPSALLKQALEVCNVKYTQAI--------PCADVLLSLVVEQCCILYQAQILQIKTLPASAAKQLS 682
Q9FGN0   708 YLLTLPQQLEPLAEGI---------------STNGdsnnedaqFFATEWMFKVAEGATALYMDQLRGIQYISDRGAQQLS 772 thale cress
Q3T1G7   713 TDIDYLINVMDALGLQPSRTLQNIATLLKAKPEEYRQVSK-----GLPRRLAATVATMRG 767 Norway rat
Q7QA49   676 TDIEYFGSVLEEMGQSLGGNLQQTVKLLRAPLESYASAAT-----GCDPELVAAIRQKRN 730 Anopheles gambiae str. PEST
EDW39280 683 VDIEYLSNVLEELGLSINLQLSQILTLLKAAPDQYLTLSS-----GCEPRLVTAIRQMRN 737
Q9FGN0   773 VDIEYLSNVLSALSMPIPPVLATFQTCLATPRGELKDVMKseagnELDCPTANLVCKMRR 832 thale cress
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