Conserved Protein Domain Family
HMG-box_EGL13-like
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cd22042: HMG-box_EGL13-like 
high mobility group (HMG)-box found in Caenorhabditis elegans protein egg laying defective 13 (EGL-13) and similar proteins
EGL-13 may act as a transcription factor that is required for uterine cell fate decisions in Caenorhabditis elegans. It controls genes required for the specification and differentiation of O(2) and CO(2)-sensing neurons and for maintaining URX sensory neuronal cell fate.
Links
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Statistics
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PSSM-Id: 438848
Aligned: 16 rows
Threshold Bit Score: 157.37
Created: 11-Apr-2019
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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putative DNA
Feature 1:putative DNA binding site [nucleic acid binding site]
Evidence:
  • Comment:based on the structure evidence that Mus musculus SOX-4 binds DNA
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1          # ## ## ##   #  #   #      ###  ##  #  ##                 #         # ####   
Q23045        327 NHIKRPMNAFMVWARDERRKILKAYPDMHNSNISKILGSRWKGMSNSEKQPYYEEQSRLSKLHMEQHPDYRYRPRPKR 404  Caenorhabditis ...
NP_726612     383 PHIKRPMNAFMVWAKDERRKILKACPDMHNSNISKILGARWKAMSNADKQPYYEEQSRLSKLHMEQHPDYRYRPRPKR 460  fruit fly
EEC19583      231 PHIKRPMNAFMVWAKDERRKILKACPDMHNSNISKILGARWKAMSNSEKQPYYEEQSRLSKLHMEKHPDYRYRPRPKR 308  black-legged tick
SVE84797      400 PHIKRPMNAFMVWAKDERRKILKACPDMHNSNISKILGARWKAMTNADKQPFYEEQSRLSKVHMEKHPDYRYRPRPKR 477  common water flea
TRY74020      661 PHIKRPMNAFMIWAKDERRKILKACPDMHNSNISKILGARWKAMSNTEKQQYYEEQARLSKVHMEKYPDYRYRPRPKR 738  Tigriopus calif...
AAD40686       56 PHIKRPMNAFMVWAKEERRKILARHPDMHNSNISKILGSKWKTMSNAEKQPYYEEQARLDKAHLEKYPDYKYKPRPKR 133  purple sea urchin
XP_006812626  501 PHIKRPMNAFMVWAKEERKKILSMHPDMHNSNISKILGAKWKAMSNADKQPYYEEQARLSKAHLEKYPDYKYKPRPKR 578  Saccoglossus ko...
NP_999637     435 PHIKRPMNAFMVWAKEERRKILARHPDMHNSNISKILGSKWKTMSNAEKQPYYEEQARLSKAHLEKYPDYKYKPRPKR 512  purple sea urchin
TPP64140      767 THIKRPMNAFMIWARDERRKILKAYPDMHNSNISKFLGARWKAMSSEAKQPYYEEQTRLSRQHMEEHPAYRYRPRPKR 844  Fasciola gigantica
KAE8749468    207 PHIKRPMNAFMVWAKDERRRILKSHPDMHNSEISKILGTHWKQMSNEEKQPYYEEQSRLSKQHMEKHPNYRYRPRPKR 284  western flower ...

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