Conserved Protein Domain Family
CDP-OH_P_transf

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pfam01066: CDP-OH_P_transf 
CDP-alcohol phosphatidyltransferase
All of these members have the ability to catalyze the displacement of CMP from a CDP-alcohol by a second alcohol with formation of a phosphodiester bond and concomitant breaking of a phosphoride anhydride bond.
Statistics
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PSSM-Id: 460049
Aligned: 230 rows
Threshold Bit Score: 51.7877
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CDB04989           26 GITPNFIT--------TTGFVLnLVATAMFIYaaelaeteaYAWIGWAGGVILFAGLFDMMDGRLARMGGMSSTFGALWD 97 
jgi:Bcell_3610     46 RLTPNMVT--------VIAGLFgIGAGLSFIF----------EQWILGAILLQLHHLMDGADGNLARLTNRCSDFGAKLD 107
jgi:Pmen_0010      26 GVTANQVTlaaalisvLLGVLLaAFSHVVWLFa-------------lIPLWMLLRMALNAVDGMLAREFGQQSKLGAYLN 92 
WP_004079594       25 GLRPDTCT--------VIAFIAsVVAGYAFYL----------SAVFAGVIFVFLNAFFDAIDGAIAREMHIASLKGDFLD 86  Methanopla...
Q12U02             25 GISPNALS--------VASLVCaALAGISFYFsv-----dnPLGALIAIFFVALNSFLDALDGAVARYLRTDSKKGDFLD 91  Methanococ...
WP_012545889       22 PVNPNIIT--------FIGMIItSSSGFVIPF-----------NLFLGGILILAGGVFDLIDGIVARVNGRTTKFGALFD 82  Thermodesu...
RogerUC:Ahos_1182  24 GVKANEIT--------IIGLVLsIIYFIVLYI---------SKNPLYGVILLALSSFSDALDGEVARISGTAGNKGAFLD 86 
Q7LXU6             27 KVSANFIT--------MLGLIFaIVYYFEIMR----------SNTTLGIIFLVFSALMDAIDGEVARVSKTVSPLGSFLD 88  Saccharolo...
jgi:Cylst_0955      4 KLIPSGLV--------LFRFLI-SPFLLWDALd--------GKTSIWFIVGFVAAFLSDIFDGIIARRLGVSTAQLRQAD 66 
WP_016481654        2 RHTPYVLI--------VLRVLL-GPTIFWISQi--------NVHSSWLALALIAAFLSDIFDGVIARRLKIVTPALRVAD 64  Chthonomon...
CDB04989           98 STLDRYseLCTLFGICyyll---mqqnDWQwagVVTFAAMv----------------GSVMV---------SYVRARAe- 148
jgi:Bcell_3610    108 QWVDQIvrLVLFVSITfvvd-----vpmWA---KVLFVATiy--------------iDVIVVhkfvlpfmrKYTIVRSkw 165
jgi:Pmen_0010      93 ELCDVVadSALYLPFAllp------gvSPL---LVVTVVL-----------------LAVIS---------EYAGVLGp- 136
WP_004079594       87 HVLDRYadIVMICGIFags------laPWT---VGVFALT-----------------GVIMS---------SYLGTQAq- 130 Methanopla...
Q12U02             92 HVIDRYsdVFIICGMFfgg------hvQWQ---IGTIAIV-----------------CVLLT---------SYLGTQAq- 135 Methanococ...
WP_012545889       83 STLDRIadGFIFLGIAwhffninddiaLYL---TILCMI------------------ASFLI---------SYVRARAe- 131 Thermodesu...
RogerUC:Ahos_1182  87 SSLDRVedTLFLSPLV-----------LYFqpvLVSLLVG-----------------ISLII---------PYLRARAe- 128
Q7LXU6             89 STLDRIedILYISAFIflgf----------ssyLVAIAVG-----------------LSLTI---------SYIRAKAe- 131 Saccharolo...
jgi:Cylst_0955     67 SWADVC--LFSSIFVS-----------AWLvyqSVLITYSlp--------------lLMVVF---------AQLIWWIvn 110
WP_016481654       65 SRTD-----------------------AWYfawILITLWRtrrrllqpyllwialeiGLQIF---------SYLFDYVky 112 Chthonomon...
CDB04989          149 ---------GlDIECKVGlm-qRPERVVVtaVGAIFCGVCanvw------vlvvPMIIIAVLANITAFW 201
jgi:Bcell_3610    166 kqwff-----------srgiipAFDIFLI--YFLIS------------------LFAIINNLEMLVFIV 203
jgi:Pmen_0010     137 ---------MiGASRRYDgpmgKSDRAFC--FGVLGAGVAtgl---------lpALWINLLLALILVLL 185
WP_004079594      131 ---------AvGAGRFYGgilgRADRLVL--TIAAGIIFIafpgyiaglnafgwLMVIFGLLGHFTAIQ 188 Methanoplanus limicola
Q12U02            136 ---------AlGIGRFYGgimgRADRLVL--ILIASLAYYiyseaifgytiigwSLVVIAIGSHITAIQ 193 Methanococcoides burt...
WP_012545889      132 ---------GlGISCNVGii-eRPERLIFlaFGCLTGLLFp-------------ILLVLTILSWATVIQ 177 Thermodesulfovibrio
RogerUC:Ahos_1182 129 ---------AlGIKAEGRgiieRGERIIF--TMIILILLFfnft------ftiyVFYLFIALSIVTVIQ 180
Q7LXU6            132 ---------SlGLKMEGRgiieRGERIIF--VFVILLLYIivskq-----vslyLFYLFMLLTAITVIQ 184 Saccharolobus solfata...
jgi:Cylst_0955    111 lvkygkpasYhTYSAKFWg-------ITL--FIAIVALFGf------------dYTGIILWLTCIVGFI 158
WP_016481654      113 rr----itsLhAYSAKVWg-------LTL--FLAIYTLLI--------------YRRAFPWIDIAIGTG 154 Chthonomonas calidirosea
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